Diosgenin protects against cationic bovine serum albumin-induced membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF- κB pathway
CONCLUSIONS: The results suggest a potential therapeutic benefit of DG against MGN due to the inhibition of the NF-κB pathway, supporting the need for further clinical trials.PMID:38516898 | DOI:10.1080/13880209.2024.2330602 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - March 22, 2024 Category: Drugs & Pharmacology Authors: Shiyan Jia Ruihua Si Guangzhen Liu Qiming Zhong Source Type: research

Elucidating the role of < em > Rhodiola rosea < /em > L. in sepsis-induced acute lung injury via network pharmacology: emphasis on inflammatory response, oxidative stress, and the PI3K-AKT pathway
CONCLUSION: This study provides foundational knowledge of the effective components, potential targets, and molecular mechanisms of RR against ALI, which could be critical for developing targeted therapeutic strategies for sepsis-induced ALI.PMID:38445620 | PMC:PMC10919309 | DOI:10.1080/13880209.2024.2319117 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - March 6, 2024 Category: Drugs & Pharmacology Authors: Lu Jiang Dongdong Yang Zhuoyi Zhang Liying Xu Qingyu Jiang Yixin Tong Lanzhi Zheng Source Type: research