Extracts of < em > Thesium chinense < /em > inhibit SARS-CoV-2 and inflammation < em > in vitro < /em >
CONCLUSION: T. chinense can be a potential candidate to fight SARS-CoV-2, and is becoming a traditional Chinese medicine candidate for treating COVID-19.PMID:37675874 | DOI:10.1080/13880209.2023.2253841 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 7, 2023 Category: Drugs & Pharmacology Authors: Juncheng Ma Juanru Wei Gang Chen Xiaowei Yan Hechun Sun Ning Li Source Type: research
Saponins from < em > Panax japonicus < /em > improve neuronal mitochondrial injury of aging rats
CONCLUSIONS: Further research on the elderly population will contribute to the development and utilization of SPJ for the treatment of neurodegenerative disorders.PMID:37667488 | DOI:10.1080/13880209.2023.2244532 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 5, 2023 Category: Drugs & Pharmacology Authors: Cheng Fan Jin-Xin Wang Zhang-E Xiong Shan-Shan Hu Ao-Jia Zhou Ding Yuan Chang-Cheng Zhang Zhi-Yong Zhou Ting Wang Source Type: research
Correction
Pharm Biol. 2023 Dec;61(1):1413. doi: 10.1080/13880209.2023.2254065.NO ABSTRACTPMID:37665171 | DOI:10.1080/13880209.2023.2254065 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 4, 2023 Category: Drugs & Pharmacology Source Type: research
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1 α signaling pathway
CONCLUSIONS: Our findings provide novel insights into the protective effect of Lok on asthma and the underlying mechanisms, providing a theoretical basis and potential treatment possibilities for this patient population.PMID:37655452 | DOI:10.1080/13880209.2023.2244543 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Jiani Liu Li Li Xue Han Yue Chen Juanjuan Diao Source Type: research
Optimization of the proportions of advantageous components in the hypolipidemic "bioequivalent substance system" of Jiang-Zhi-Ning and its mechanism of action
CONCLUSIONS: These findings provided new feasible ideas and methods for the elucidation of the pharmacodynamic material basis.PMID:37655554 | DOI:10.1080/13880209.2023.2243999 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Yumiao Li Yan Zhang Yu Zhang Tianfeng Lin Yanyan Gao Yuan Cai Chang Zhou Leyi Yang Bin Liu Shifen Dong Yanyan Jiang Source Type: research
Bu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway
CONCLUSION: BSTJFs might have therapeutic potential on oxidative stress and mitochondrial damage through the HDAC3/HSP90AA pathway which encourages further clinical trials.PMID:37655754 | DOI:10.1080/13880209.2023.2249193 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Hui Zhang Huihua Wang Qing Zhang Hui Wang Yuhang Zhu Fangfang Wang Jun Lin Jue Zhou Fan Qu Source Type: research
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1 α signaling pathway
CONCLUSIONS: Our findings provide novel insights into the protective effect of Lok on asthma and the underlying mechanisms, providing a theoretical basis and potential treatment possibilities for this patient population.PMID:37655452 | DOI:10.1080/13880209.2023.2244543 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Jiani Liu Li Li Xue Han Yue Chen Juanjuan Diao Source Type: research
Optimization of the proportions of advantageous components in the hypolipidemic "bioequivalent substance system" of Jiang-Zhi-Ning and its mechanism of action
CONCLUSIONS: These findings provided new feasible ideas and methods for the elucidation of the pharmacodynamic material basis.PMID:37655554 | DOI:10.1080/13880209.2023.2243999 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Yumiao Li Yan Zhang Yu Zhang Tianfeng Lin Yanyan Gao Yuan Cai Chang Zhou Leyi Yang Bin Liu Shifen Dong Yanyan Jiang Source Type: research
Bu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway
CONCLUSION: BSTJFs might have therapeutic potential on oxidative stress and mitochondrial damage through the HDAC3/HSP90AA pathway which encourages further clinical trials.PMID:37655754 | DOI:10.1080/13880209.2023.2249193 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Hui Zhang Huihua Wang Qing Zhang Hui Wang Yuhang Zhu Fangfang Wang Jun Lin Jue Zhou Fan Qu Source Type: research
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1 α signaling pathway
CONCLUSIONS: Our findings provide novel insights into the protective effect of Lok on asthma and the underlying mechanisms, providing a theoretical basis and potential treatment possibilities for this patient population.PMID:37655452 | DOI:10.1080/13880209.2023.2244543 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Jiani Liu Li Li Xue Han Yue Chen Juanjuan Diao Source Type: research
Optimization of the proportions of advantageous components in the hypolipidemic "bioequivalent substance system" of Jiang-Zhi-Ning and its mechanism of action
CONCLUSIONS: These findings provided new feasible ideas and methods for the elucidation of the pharmacodynamic material basis.PMID:37655554 | DOI:10.1080/13880209.2023.2243999 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Yumiao Li Yan Zhang Yu Zhang Tianfeng Lin Yanyan Gao Yuan Cai Chang Zhou Leyi Yang Bin Liu Shifen Dong Yanyan Jiang Source Type: research
Bu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway
CONCLUSION: BSTJFs might have therapeutic potential on oxidative stress and mitochondrial damage through the HDAC3/HSP90AA pathway which encourages further clinical trials.PMID:37655754 | DOI:10.1080/13880209.2023.2249193 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 1, 2023 Category: Drugs & Pharmacology Authors: Hui Zhang Huihua Wang Qing Zhang Hui Wang Yuhang Zhu Fangfang Wang Jun Lin Jue Zhou Fan Qu Source Type: research
Novel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/ β-catenin signalling pathway
CONCLUSIONS: SMYA has a protective effect against AS, which may be related to its anti-VV angiogenesis in plaques, suggesting that SMYA has the potential as a novel botanical formulation in the treatment of AS.PMID:37651108 | PMC:PMC10472848 | DOI:10.1080/13880209.2023.2249061 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 31, 2023 Category: Drugs & Pharmacology Authors: Zhongwen Qi Zhipeng Yan Ke Zhu Yueyao Wang Yajie Fan Tingting Li Junping Zhang Source Type: research
