Proliferative Inhibition Apoptotic Induction Migratory Suppression of Piper nigrum Extract on HeLa Cervical Cell Line
Benjaporn Buranrat* (Source: Indian Journal of Pharmaceutical Sciences)
Source: Indian Journal of Pharmaceutical Sciences - December 9, 2022 Category: Drugs & Pharmacology Source Type: research
Supplementation with the Traditional Thai Polyherbal Medicine NawaTab Ameliorates Lipid Profiles in High-Fat Diet-Induced Hyperlipidemic Rats
This study aimed to describe the antihyperlipidemic properties of NawaTab in a well-described model of high-fat diet (HFD)-induced hyperlipidemic rats. Decoction of Nawametho containing equal quantities of Aegle marmelos (L.), Carthamus tinctorius L., Hibiscus sabdariffa Linn., Phyllanthus emblica L., Piper longum L., Piper nigrum L., Terminalia bellirica (Gaertn.) Roxb., Terminalia chebula Retz., and Zingiber officinale Roscoe were prepared. The HFD-fed rats were administered NawaTab for 4 consecutive weeks starting from the ninth week of HFD treatment at a dose of 125 mg/kg (p.o.). Anthropometric parameters, serum lipid ...
Source: Evidence-based Complementary and Alternative Medicine - December 1, 2022 Category: Complementary Medicine Authors: Apichaya Niyomchan Wasapon Chatgat Bodin Chatawatee Thaweeporn Keereekoch Patcharawalai Jaisamut Sasitorn Chusri Nongluk Kunworarath Source Type: research
[ASAP] Novel Bisamide Alkaloids Enantiomers from Pepper Roots ( < named-content content-type="genus-species" xlink:type="simple" > Piper nigrum L. < /named-content > ) with Acetylcholinesterase Inhibitory and Anti-Neuroinflammatory Effects
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.2c06733 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - November 30, 2022 Category: Food Science Authors: Yu-Xi Wang, Zhi-Yong Xu, Shu-Yan Qin, Ning-Ning Du, Guo-Dong Yao, Bin Lin, Xiao-Xiao Huang, and Shao-Jiang Song Source Type: research
The Use of Herbal Medicine in the Treatment of Vitiligo: An Updated Review
The objective of the present review is to provide an
updated overview on the most frequently used medicinal plants in the treatment of vitiligo. A bibliographical search was carried out in scientific databases Pubmed, Scifinder, Scopus, Google
Scholar, and Medline up to October 2021 using the descriptors vitiligo, herbal, medicinal plants, and alternative therapies. In our search, the highest number of published studies comprise
plants commonly used in traditional herbal medicine, highlighting the usefulness of ethnopharmacology in the discovery of new therapeutic agents. The review outlines current understa...
Source: Planta Medica - November 15, 2022 Category: Drugs & Pharmacology Authors: Castillo, Encarna Gonz ález-Rosende, María Eugenia Mart ínez-Solís, Isabel Tags: Reviews Source Type: research
From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders
Aging is described as an advanced time-related collection of changes that may negatively affect with the risk of several diseases or death. Aging is a main factor of several age-related neurological disorders, including neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, and dementia), stroke, neuroinflammation, neurotoxicity, brain tumors, oxidative stress, and reactive oxygen species (ROS). Currently available medications for age-related neurological disorders may lead to several side effects, such as headache, diarrhea, nausea, gastrointestinal (GI) diseases, dyskinesia, and hallucinosis. These day...
Source: Frontiers in Pharmacology - November 10, 2022 Category: Drugs & Pharmacology Source Type: research
De novo transcriptome profiling unveils the regulation of phenylpropanoid biosynthesis in unripe Piper nigrum berries
Black pepper (Piper nigrum L.) is rich in bioactive compounds that make it an imperative constituent in traditional medicines. Although the unripe fruits have long been used in different Ayurvedic formulations, t... (Source: BMC Plant Biology)
Source: BMC Plant Biology - October 26, 2022 Category: Biology Authors: Sweda Sreekumar, Kattupalli Divya, Nisha Joy and E. V. Soniya Tags: Research Source Type: research
Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain with no potential CNS side effects
Curcumin and piperine are major bioactive compounds of Curcuma longa and Piper nigrum, widely consumed as spices and flock medicine. The combinational use of these plants is a common practice in Southeast Asia. S... (Source: Chinese Medicine)
Source: Chinese Medicine - October 23, 2022 Category: Complementary Medicine Authors: Pawana Boonrueng, Peththa Wadu Dasuni Wasana, Hasriadi, Opa Vajragupta, Pornchai Rojsitthisak and Pasarapa Towiwat Tags: Research Source Type: research
Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology
Appl Biochem Biotechnol. 2022 Oct 11. doi: 10.1007/s12010-022-04132-y. Online ahead of print.ABSTRACTMedicinal or herbal spices are grown in tropical moist evergreen forestland, surrounding most of the tropical and subtropical regions of Eastern Himalayas in India (Sikkim, Darjeeling regions), Bhutan, Nepal, Pakistan, Iran, Afghanistan, a few Central Asian countries, Middle East, USA, Europe, South East Asia, Japan, Malaysia, and Indonesia. According to the cultivation region surrounded, economic value, and vogue, these spices can be classified into major, minor, and colored tropical spices. In total, 24 tropical spices an...
Source: Applied Biochemistry and Biotechnology - October 11, 2022 Category: Biochemistry Authors: Debopriya Mandal Tanmay Sarkar Runu Chakraborty Source Type: research
Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology
Appl Biochem Biotechnol. 2022 Oct 11:1-195. doi: 10.1007/s12010-022-04132-y. Online ahead of print.ABSTRACTMedicinal or herbal spices are grown in tropical moist evergreen forestland, surrounding most of the tropical and subtropical regions of Eastern Himalayas in India (Sikkim, Darjeeling regions), Bhutan, Nepal, Pakistan, Iran, Afghanistan, a few Central Asian countries, Middle East, USA, Europe, South East Asia, Japan, Malaysia, and Indonesia. According to the cultivation region surrounded, economic value, and vogue, these spices can be classified into major, minor, and colored tropical spices. In total, 24 tropical spi...
Source: Applied Biochemistry and Biotechnology - October 11, 2022 Category: Biochemistry Authors: Debopriya Mandal Tanmay Sarkar Runu Chakraborty Source Type: research
Molecules, Vol. 27, Pages 6590: Natural Phytocompounds from Common Indian Spices for Identification of Three Potential Inhibitors of Breast Cancer: A Molecular Modelling Approach
haman
Breast cancer is the second most common cancer-related cause of death for women throughout the globe. In spite of some effective measures, the main concerns with traditional anti-cancer chemotherapy are its low bioavailability, physical side effects, acquired resistance of cancer cells and non-specific targeting. Now researchers have taken the initiative to establish natural product-based therapy methods and to identify viable hits for future lead optimization in the development of breast cancer medication. Our study aims to identify the potent phytocompounds from five very popular Indian spices (Zingiber officin...
Source: Molecules - October 5, 2022 Category: Chemistry Authors: Samik Hazra Anindya Sundar Ray Chowdhury Habibur Rahaman Tags: Article Source Type: research
Comparative analysis of the chloroplast genomes of eight Piper species and insights into the utilization of structural variation in phylogenetic analysis
This study performed chloroplast genome sequencing of eight poorly studied Piper species and a comparative analysis with black pepper (Piper nigrum). All examined species were highly similar in gene content, with 79 protein-coding genes, 24 tRNAs, and four rRNAs. They also harbored significant structural differences: The number of SSRs ranged from 63 to 87, over 10,000 SNPs were detected, and over 1,000 indels were found. The spatial distribution of structural differences was uneven, with the IR and LSC being relatively more conserved and the SSC region highly variable. Such structural variations of the chloroplast genome ...
Source: Frontiers in Genetics - September 29, 2022 Category: Genetics & Stem Cells Source Type: research
Molecules, Vol. 27, Pages 6403: Spices Volatilomic Fingerprinting & mdash;A Comprehensive Approach to Explore Its Authentication and Bioactive Properties
This study aimed to establish the volatilomic fingerprint of six of the most consumed spices all over the world (saffron (Crocus sativus L.), cinnamon (Cinnamomum verum), cumin (Cuminum cyminum L.), black pepper, (Piper nigrum L.), sweet paprika (Capsicum annuum L.), and curry (a mix of different herbs and spices)). Based on headspace solid phase microextraction (HS-SPME) followed by gas chromatography-mass spectrometry (GC-MS) analysis, this is a powerful strategy to explore and establish the spice&rsquo;s volatile pattern and unravel the potential health benefits related to the most important VOMs identified in e...
Source: Molecules - September 28, 2022 Category: Chemistry Authors: Sergio Izcara Rosa Perestrelo Sonia Morante-Zarcero Isabel Sierra Jos é S. Câmara Tags: Article Source Type: research
The genotoxic, cytotoxic and growth regulatory effects of plant secondary metabolite β-caryophyllene on polyphagous pest Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae)
Toxicon. 2022 Sep 24:S0041-0101(22)00275-6. doi: 10.1016/j.toxicon.2022.09.016. Online ahead of print.ABSTRACTUse of secondary metabolites as an alternative to organic pesticides is an eco-friendly and safe strategy in pest management. β-caryophyllene [(1R,4E,9S)-4,11,11-trimethyl-8-methylene bicyclo [7.2.0]undec-4-ene], a natural sesquiterpene is found as an essential oil in many plants like Syzygium aromaticum, Piper nigrum, Cannabis sativa. The present study aims at exploring the insecticidal, genotoxic and cytotoxic potential of β-caryophyllene against common cutworm Spodoptera litura (Fab.), a major polyphagous pest...
Source: Toxicon - September 27, 2022 Category: Toxicology Authors: Evani Mahajan Sumit Singh None Diksha Sanehdeep Kaur Satwinder Kaur Sohal Source Type: research
