Bioactive acridone alkaloids and their derivatives from Citrus aurantium (Rutaceae)
Publication date: February 2019Source: Phytochemistry Letters, Volume 29Author(s): Samuel Bissim, Sidonie Béatrice Kenmogne, Alain Tadjong Tcho, Mehreen Lateef, Ayaz Ahmed, Emmanuel Ngeufa Happi, Jean Duplex Wansi, Muhammad Shaiq Ali, Alain François Kamdem WaffoAbstractPhytochemical studies on Citrus aurantium led to the isolation and characterization of a new secotirucallane, namely 1β-hydroxy-3,4-secotirucalla-4(28)-7,24-trien-3,21-dioic acid (1), together with the previously reported compounds citracridone I (2), citruisinine II (3), citracridone II (4), 5-hydroxynoracronycine (5), citpressine II (6), citpressine I (...
Source: Phytochemistry Letters - December 11, 2018 Category: Chemistry Source Type: research
Optimization and characterization of pectin extracted from sour orange peel by ultrasound assisted method.
Abstract
In this work, a Box-Behnken design (BBD) with three variables (ultrasound power, irradiation time and pH) in three levels was applied for pectin extraction optimization. The optimization process showed that the maximum extraction yield was 28.07 ± 0.67% in ultrasound power of 150 W, irradiation time of 10 min and pH of 1.5 (as optimum conditions). In these conditions, ash, moisture and protein contents of SOPP were 1.89 ± 0.51, 8.81 ± 0.68 and 1.45 ± 0.23%, respectively. HPLC analysis indicated that 65.3% of the extracted pectin was galacturonic acid and approximately 72% o...
Source: International Journal of Biological Macromolecules - December 10, 2018 Category: Biochemistry Authors: Hosseini SS, Khodaiyan F, Kazemi M, Najari Z Tags: Int J Biol Macromol Source Type: research
Determination of nutritional composition in citrus fruits (C. aurantium) during maturity
This study was conducted through three stages of fruit maturity (green, yellow and orange). Total polyphenols, flavonoids, β-carotene, total chlorophyll, ascorbic acid, acidity, total soluble solid and the minerals (Ca, Mg, Zn, Na, K, Fe, Mn Cu) were evaluated. Moreover, the relationship between the total polyphenol, flavonoids and the antioxidant activity was determined. Design/methodology/approach Total polyphenols were determined by the Folin-Ciocalteu method. Flavonoids were assessed by the aluminum chloride colorimetric method. Ca, Mg, Zn, Fe, Mn and Cu were measured using an atomic absorption spectrophotometer. K a...
Source: Nutrition and Food Science - November 9, 2018 Category: Nutrition Source Type: research
Bioactive constituents obtained from the fruits of Citrus aurantium
AbstractThree new compounds, citrusauranosides A (1), B (2), and C (3), along with 22 known compounds (4–25) were obtained from the 70% ethanol –water extract of the fruits ofCitrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds,14,15,17 and23 were firstly obtained fromCitrus genus, and the NMR data of17 is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result,1,4–8, and11 displayed significant inhibitory effects on contraction tension. (Source: Journal of Natural Medicines)
Source: Journal of Natural Medicines - October 26, 2018 Category: Drugs & Pharmacology Source Type: research
Therapeutic activity of sour orange albedo extract and abundant flavanones loaded silica nanoparticles against acrylamide-induced hepatotoxicity
Publication date: Available online 9 September 2018Source: Toxicology ReportsAuthor(s): M.Z. Rizk, D.M. Abo-El-matty, H.F. Aly, H.I. Abd-Alla, S.M. Saleh, E.A. Younis, A.M. Elnahrawy, A.A. HarounAbstractThe current research aims to demonstrate the therapeutic effect of sour orange albedo extract (SOAE) and two flavanones loaded-tetraethylorthosilicate (TEOS) using sol-gel technique, in adose100 mg/kg body weight taken orally or45 days against acrylamide (ACR)toxicity in rats. This was achieved through measuring the activities of specific biochemical parameters related to liver functions in tissue of ACR intoxicated rats ...
Source: Toxicology Reports - September 10, 2018 Category: Toxicology Source Type: research
Acridone alkaloids from the stem bark of Citrus aurantium display selective cytotoxicity against breast, liver, lung and prostate human carcinoma cells
ConclusionThe results obtained from this study have provided some evidence for the ethnomedicinal use of C. aurantium against cancer and the acridone alkaloids present in its stem bark, have appeared to be responsible for the anticancer effects.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - September 4, 2018 Category: Drugs & Pharmacology Source Type: research
Comparative analysis of chemical composition, antimicrobial and antioxidant activity of citrus essential oils from the main cultivated varieties in China
Publication date: November 2018Source: LWT, Volume 97Author(s): Jia-jing Guo, Zhi-peng Gao, Jin-lan Xia, Mark A. Ritenour, Gao-yang Li, Yang ShanAbstractIn this work, the chemical composition, antimicrobial and antioxidant activities of fourteen species of citrus essential oils (EOs) from the main cultivated varieties in China were evaluated and compared. A total of more than 200 components were identified, which are mainly composed of terpenes, alcohols, aldehydes, esters, ketones and acids. Antimicrobial ability of fourteen EOs and seven major components were tested against six bacteria and two yeasts. The susceptibility...
Source: LWT Food Science and Technology - August 31, 2018 Category: Food Science Source Type: research
Potential Metabolic Drug –Drug Interaction of Citrus aurantium L. (Rutaceae) Evaluating by Its Effect on 3 CYP450
Lu Zhou, Man Cui, Linlin Zhao, Dongsheng Wang, Tao Tang, Wenbo Wang, Sheng Wang, Huiyong Huang, Xinjian Qiu (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - August 31, 2018 Category: Drugs & Pharmacology Source Type: research
Multivariate curve resolution-correlation optimized warping applied to the complex GC-MS signals; toward comparative study of peel chemical variability of Citrus aurantium L. varieties
Publication date: December 2018Source: Microchemical Journal, Volume 143Author(s): Fatemeh Azimi, Mohammad Hossein FatemiAbstractMultivariate curve resolution based correlation optimized warping (MCR-COW) was proposed as an efficient alignment method to correct the undesirable elution time shifts where co-eluting and shift occurred at the same time and the use of COW algorithm on the raw data often fails. For this purpose, the primary implementation of extended multivariate curve resolution- alternating least squares (MCR-ALS) helped to reduce the underlying complexity of gas chromatography–mass spectrometry (GC–MS) da...
Source: Microchemical Journal - August 3, 2018 Category: Chemistry Source Type: research
Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study.
CONCLUSION: The aromatherapy with Citrus aurantium blossom improved the symptoms of premenstrual syndrome.
PMID: 30057033 [PubMed - in process] (Source: Complementary Therapies in Clinical Practice)
Source: Complementary Therapies in Clinical Practice - July 31, 2018 Category: Complementary Medicine Authors: Heydari N, Abootalebi M, Jamalimoghadam N, Kasraeian M, Emamghoreishi M, Akbarzadeh M Tags: Complement Ther Clin Pract Source Type: research
Multivariate curve resolution-correlation optimized warping applied to the complex GC–MS signals; toward comparative study of peel chemical variability of Citrus aurantium L. varieties
Publication date: Available online 30 July 2018Source: Microchemical JournalAuthor(s): Fatemeh Azimi, Mohammad Hossein FatemiAbstractMultivariate curve resolution based correlation optimized warping (MCR-COW) was proposed as an efficient alignment method to correct the undesirable elution time shifts where co-eluting and shift occurred at the same time and the use of COW algorithm on the raw data often fails. For this purpose, the primary implementation of extended multivariate curve resolution- alternating least squares (MCR-ALS) helped to reduce the underlying complexity of gas chromatography–mass spectrometry (GC–MS...
Source: Microchemical Journal - July 31, 2018 Category: Chemistry Source Type: research
The influence of citrus aurantium and caffeine complex versus placebo on the cardiac autonomic response: a double blind crossover design
The purpose of this study was to examine the resting cardiac autonomic nervous system ’s response to the ingestion of a complex containing Citrus aurantium + Caffeine (CA + C) and its influence on recovery followi... (Source: Journal of the International Society of Sports Nutrition)
Source: Journal of the International Society of Sports Nutrition - July 24, 2018 Category: Sports Medicine Authors: Brian Kliszczewicz, Emily Bechke, Cassie Williamson, Paul Bailey, Wade Hoffstetter, John McLester and Cherilyn McLester Tags: Research article Source Type: research
Sensors, Vol. 18, Pages 1922: Classification of Bitter Orange Essential Oils According to Fruit Ripening Stage by Untargeted Chemical Profiling and Machine Learning
This study provides a novel strategy for the quality control of bitter orange EO without subjective methods. (Source: Sensors)
Source: Sensors - June 13, 2018 Category: Biotechnology Authors: Saeedeh Taghadomi-Saberi S ílvia Mas Garcia Amin Allah Masoumi Morteza Sadeghi Santiago Marco Tags: Article Source Type: research
Preventive Effects of an UPLC-DAD-MS/MS Fingerprinted Hydroalcoholic Extract of Citrus aurantium in a Mouse Model of Ulcerative Colitis
Planta Med DOI: 10.1055/a-0604-2797Although traditionally used to improve indigestion, diarrhea, dysentery, and constipation, the therapeutic effects of Citrus aurantium on intestinal inflammation remain unclear. The aim of this study was to evaluate the beneficial effects and to identify the active components of a hydroalcoholic extract of C. aurantium (HECA) on ulcerative colitis. HECA was prepared with 70% ethanol solution in water and extracted at 37 °C for 12 h in triplicate, filtered through a sieve, and lyophilized. Phytochemical identification of HECA was performed by ultra-performance liquid chromatography-di...
Source: Planta Medica - May 4, 2018 Category: Drugs & Pharmacology Authors: Hwang, Youn-Hwan Ma, Jin Yeul Tags: Original Papers Source Type: research
