HPLC-UV fingerprint profile and bioactivity of Citrus aurantium var. deliciosa fruits: peel and seeds on certain plant-parasitic nematodes
A potential approach to valorize citrus peel (P) in addition to seed (S), which remain wastes of the juice abstraction manufacturing, is to custom them as accepted bionematicides. However, information on the limonoids as well aspolyphenolics contents of the peel and seeds of Citrus aurantium var. deliciosa were limited. In the present study, methanolic extracts of the peel and seeds of C. au... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - April 16, 2017 Category: Complementary Medicine Source Type: research
Molecules, Vol. 22, Pages 591: The Effect of Citrus Essential Oils and Their Constituents on Growth of Xanthomonas citri subsp. citri
Citrus bacterial canker (CBC) caused by Xanthomonas citri subsp. citri (Xcc), is the most devastating of the citrus diseases worldwide. During our study, we found that Essential oils (EOs) of some citrus cultivars are effective on Xcc. Therefore, it prompted us to determine the plant metabolites responsible for the antibacterial properties. We obtained EOs from some locally cultivated citrus by using a Clevenger apparatus and their major constituents were identified by gas chromatography/mass spectrometry (GC-MS). The effect of Citrus aurantium, C. aurantifolia, Fortunella sp. EOs and their major constituents were evaluate...
Source: Molecules - April 14, 2017 Category: Chemistry Authors: Hossein Mirzaei-Najafgholi Saeed Tarighi Morteza Golmohammadi Parissa Taheri Tags: Article Source Type: research
Two new phenolic glycosides isolated from the fruits of Citrus aurantium
Publication date: January 2017 Source:Chinese Journal of Natural Medicines, Volume 15, Issue 1 Author(s): Xiao-Li ZHANG, Wen-Feng XU, Gang CHEN, Hai-Feng WANG, Yue-Hu PEI The present study was designed to investigate the chemical constituents of the fruit of Citrus aurantium L.. The compounds were isolated and purified by various chromatographic techniques, and their structures were elucidated on the basis of physicochemical properties and spectral data. Two new phenolic glycosides (compounds 1 and 2) were obtained and identified as 1-O-3, 5-dihydroxyphenyl-(6-O-4-hydroxybenzoyl)-β-D-glucopyranoside (1) and 1-O-3, ...
Source: Chinese Journal of Natural Medicines - March 1, 2017 Category: Complementary Medicine Source Type: research
Phytochemical compounds in sport nutrition: Synephrine and hydroxycitric acid (HCA) as examples for evaluation of possible health risks
This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 28, 2017 Category: Nutrition Authors: Nadiya Bakhiya, Rainer Ziegenhagen, Karen I. Hirsch ‐Ernst, Birgit Dusemund, Klaus Richter, Katharina Schultrich, Sophie Pevny, Bernd Schäfer, Alfonso Lampen Tags: Review Source Type: research
[Risk assessment of synephrine in dietary supplements].
In conclusion, consumption of high amounts of synephrine, especially in combination with caffeine and physical exercise, is associated with an increased risk of adverse effects on the cardiovascular system. According to the assessment by the BfR (Bundesinstitut für Risikobewertung), daily intake of synephrine through dietary supplements should not exceed the median intake from conventional foods.
PMID: 28058460 [PubMed - as supplied by publisher] (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - January 4, 2017 Category: Global & Universal Authors: Bakhyia N, Dusemund B, Richter K, Lindtner O, Hirsch-Ernst KI, Schäfer B, Lampen A Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research
Chemical Compositions of the Peel Essential Oil of Citrus aurantium and Its Natural Larvicidal Activity against the Malaria Vector Anopheles stephensi (Diptera: Culicidae) in Comparison with Citrus paradisi.
CONCLUSION: The results obtained from this study suggest that the limonene of peel essential oil of C. aurantium is promising as larvicide against An. stephensi larvae and could be useful in the search for new natural larvicidal compounds.
PMID: 28032110 [PubMed] (Source: Iranian Journal of Arthropod-Borne Diseases)
Source: Iranian Journal of Arthropod-Borne Diseases - December 31, 2016 Category: Infectious Diseases Tags: J Arthropod Borne Dis Source Type: research
Analysis of pharmaceutical adulterants in plant food supplements by UHPLC-MS/MS.
Abstract
A method based on the Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) extraction and ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was successfully developed and validated for the analysis of 26 pharmaceutical compounds belonging to different therapeutic classes (anorexics, stimulants, anxiolytics, antidepressants and laxatives), which are all prone to be illegally added into weight-loss plant food supplements (PFS) for their pharmacological activity. Internal standard calibration with six isotopically labelled compounds rendered good lin...
Source: European Journal of Pharmaceutical Sciences - December 23, 2016 Category: Drugs & Pharmacology Authors: Paíga P, Rodrigues MJ, Correia M, Amaral JS, Oliveira MB, Delerue-Matos C Tags: Eur J Pharm Sci Source Type: research
Control of stress-induced depressive disorders by So-ochim-tang-gamibang, a Korean herbal medicine
Conclusions Taken together, our data suggested that SOCG may have potential as an antidepressant agent controlling depressive behaviors and corticosterone-induced neuronal damage caused by chronic stress. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - December 23, 2016 Category: Drugs & Pharmacology Source Type: research
Protective effects of a polymethoxy flavonoids-rich Citrus aurantium peel extract on liver fibrosis induced by bile duct ligation in mice
Conclusions CAE can efficiently regulate BDL-induced liver injury with antioxidant, anti-inflammatory, and antiapoptotic activities. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research
Protective effects of peel and seed extracts of Citrus aurantium on glutamate-induced cytotoxicity in PC12 cell line.
In this study, the neuroprotective effects of Citrus aurantium in the glutamate-induced rat's adrenal pheochromocytoma cell line (PC12 cells) were investigated. The cell viability and apoptotic cell death were measured using MTT and propidium iodine (PI)-staining methods, respectively. In addition, intracellular ROS and malondialdehyde (MDA) levels were determined by fluorometric methods. The results showed that glutamate cytotoxicity in PC12 cells was accompanied by an increment of MDA content, ROS generation, and apoptotic induction. However, pretreatment with peel and seed extracts of C. aurantium significantly reduced ...
Source: Folia Neuropathologica - October 22, 2016 Category: Pathology Authors: Hosseini A, Sadeghnia HR, Rajabian A Tags: Folia Neuropathol Source Type: research
A cell ‐based high‐throughput protocol to screen entry inhibitors of highly pathogenic viruses with Traditional Chinese Medicines
This study represents a proof‐of‐principle investigation supporting the suitability of this assay for rapid screening TCMs and identifying putative entry inhibitors for these viruses. This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - October 4, 2016 Category: Virology Authors: Yong Yang, Han Cheng, Hui Yan, Peng ‐Zhan Wang, Rong Rong, Ying‐Ying Zhang, Cheng‐Bo Zhang, Rui‐kun Du, Li‐Jun Rong Tags: Research Article Source Type: research
Fate and control of pathogenic and spoilage micro ‐organisms in orange blossom (Citrus aurantium) and rose flower (Rosa centifolia) hydrosols
ConclusionPathogenic micro‐organisms likely represent a low risk in rose flower and orange blossom hydrosol. However the oligotrophic character of hydrosols and the antimicrobial properties of their essential oils do not prevent microbiological spoilage by the naturally present microbiota.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)
Source: Journal of Applied Microbiology - August 31, 2016 Category: Microbiology Authors: C écile Labadie, Céline Cerutti, Frédéric Carlin Tags: Original Article Source Type: research
Effects of Lemon and Seville Orange Juices on the Pharmacokinetic Properties of Sildenafil in Healthy Subjects
ConclusionsAlthough it is considered as a moderate CYP3A4 inhibitor, Seville orange only caused a mild increase in exposure to sildenafil after a single oral dose, without manifestation of any adverse effects. The enhanced bioavailability of sildenafil by Seville orange may be attributed to inhibition of its intestinal first-pass effect (CYP3A4 and or p-glycoprotein). Lemon juice, in contrast, had no effects on the pharmacokinetics of sildenafil. (Source: Drugs in R&D)
Source: Drugs in R&D - August 21, 2016 Category: Drugs & Pharmacology Source Type: research
Supercritical extraction from Citrus aurantium amara peels using CO2 with ethanol as co-solvent
This study aimed further exploitation of Citrus aurantium L. var amara peels for the recovery of bioactive components by using supercritical CO2 extraction with ethanol as co-solvent. In order to optimize the extract yield a central composite design and the response surface methodology were used. The following independent variables were investigated: pressure (130–210) bar, static time (30–70) min and CO2 flow rate (2.1–3.3) kgh−1. The statistical results show a significant quadratic effect of both pressure and flow rate of CO2. In addition, Sovová’s model was successfully applied to the experimental data. The p...
Source: The Journal of Supercritical Fluids - July 26, 2016 Category: Chemistry Source Type: research
Metals Content in Herbal Supplements.
Abstract
Obesity has become an international epidemic. To evaluate the level of metals in extracts of plants prescribed as weight loss supplements, different brands containing Camellia sinensis (L.) Kuntze, Citrus aurantium L., Cordia ecalyculata Vell, Ilex paraguariensis A. St.-Hil, Cissus quadrangularis L., Senna alexandrina Mill were purchased in local market, hot acid digested, and analyzed while metal content by inductively coupled plasma optical emission spectrometry, ICP-OES. Quality assurance and quality control tests were carried out in order to monitor and control the reliability of the analytica...
Source: Biological Trace Element Research - June 24, 2016 Category: Biology Authors: Barrella MV, Heringer OA, Cardoso PM, Pimentel EF, Scherer R, Lenz D, Endringer DC Tags: Biol Trace Elem Res Source Type: research
