Physico-Chemical Characteristics and antioxidant Activity of Phenolic Compounds and oil of Citrus aurantium Seeds from Northwest Algeria
Sour orange (Citrus aurantium) is a tree of the family of Rutaceae. It is cultivated today in many parts of the world; the fruit, leaves, twigs and flowers have numerous applications in food and perfumery. Citrus aurantium used in this study originate from Tlemcen in North East of Algeria.Our study focused firstly on the physicochemical analysis of seed oil of sour orange namely the determination of indices, fatty acids, vitamin E and polyphenols.Secondly we evaluated total phenols, flavonoids, condensed tannins of Citrus aurantium seeds and their antioxidant activity of using in vitro methods: ferric reducing antioxidant ...
Source: International Journal of Phytomedicine - January 25, 2016 Category: Science Authors: Brixi Nassima Gormat Source Type: research

Anxiolytic Effect of Citrus aurantium L. on Patients with Chronic Myeloid Leukemia
The bone marrow aspiration procedure is used in hematological diseases and consists of a painful, invasive procedure causing anxiety‐associated symptoms. The present study assessed the effect of Citrus aurantium L. essential oil on the treatment of anxiety, in the moment that precedes the collection of medullary material in patients with chronic myeloid leukemia (CML). Volunteers from both sexes were divided into groups receiving either the C. aurantium essential oil through inhalation, diazepam (10 mg), or the placebo. The evaluation was performed through psychometric scales [State‐Trait Anxiety Inventory (STAI)] an...
Source: Phytotherapy Research - January 20, 2016 Category: Biochemistry Authors: Flávia Cristina Fernandes Pimenta, Mateus Feitosa Alves, Martina Bragante Fernandes Pimenta, Silvia Adelaide Linhares Melo, Anna Alice Figueirêdo de Almeida, José Roberto Leite, Liana Clébia de Morais Pordeus, Margareth de Fátima Formiga Melo Diniz, Tags: Research Article Source Type: research

Optimization of microwave assisted extraction of pectin from sour orange peel and its physicochemical properties
Publication date: 20 April 2016 Source:Carbohydrate Polymers, Volume 140 Author(s): Seyed Saeid Hosseini, Faramarz Khodaiyan, Mohammad Saeid Yarmand Microwave assisted extraction technique was used to extract pectin from sour orange peel. Box–Behnken design was used to study the effect of irradiation time, microwave power and pH on the yield and degree of esterification (DE) of pectin. The results showed that the optimum conditions for the highest yield of pectin (29.1%) were obtained at pH of 1.50, microwave power of 700W, and irradiation time of 3min. DE values of pectin ranged from 1.7% to 37.5%, indicating ...
Source: Carbohydrate Polymers - January 11, 2016 Category: Biomedical Science Source Type: research

A new phenolic glycoside and two new monoterpenoid furocoumarins from Aurantii Fructus Immaturus.
Abstract A new phenolic glycoside, citrauranoside A (1), and two new monoterpenoid furocoumarins, citraurancoumarin A (2) and citraurancoumarin B (3), along with four known compounds (4-7) were isolated from the young fruit of Citrus aurantium L. The structures were elucidated by their comprehensive analysis including 1D, 2DNMR, IR and mass spectra. PMID: 26728329 [PubMed - as supplied by publisher] (Source: Natural Product Research)
Source: Natural Product Research - January 5, 2016 Category: Biochemistry Authors: Xiong Y, Chang M, Deng K, Luo Y Tags: Nat Prod Res Source Type: research

The effects of cognitive reappraisal following retrieval-procedures designed to destabilize alcohol memories in high-risk drinkers
Conclusions This study provides partial preliminary support for the idea that a common psychotherapeutic strategy used in the context of putative memory retrieval-destabilization can alter accessibility of alcohol semantic networks. Further research delineating the necessary and sufficient requirements for producing alterations in alcohol memory performance based on memory destabilization is still required. (Source: Psychopharmacology)
Source: Psychopharmacology - December 14, 2015 Category: Psychiatry Source Type: research

Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey.
CONCLUSION: These results might be useful in determining the toxic effects of herbs and lead to precautions being taken in regards to their consumption. PMID: 26281312 [PubMed - indexed for MEDLINE] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - December 2, 2015 Category: Journals (General) Tags: Turk J Med Sci Source Type: research

An evidence-based systematic review of bitter orange (Citrus aurantium) by the Natural Standard Research Collaboration.
This article includes written and statistical analysis of clinical trials, plus a compilation of expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing. PMID: 24237193 [PubMed - indexed for MEDLINE] (Source: Journal of Dietary Supplements)
Source: Journal of Dietary Supplements - November 18, 2015 Category: Nutrition Tags: J Diet Suppl Source Type: research

Absence of furanocoumarins in Advantra Z® (Citrus aurantium, bitter orange) extracts.
This study examined the furanocoumarin content of four standardized bitter orange extracts (Advantra Z®) by liquid chromatography-mass spectroscopy. The results indicated that the total furanocoumarin content of each of the four extracts was less than 20 μg/g, amounts insufficient to exert significant effects on the metabolism of susceptible drugs in human subjects at the doses commonly used for these extracts. PMID: 25026202 [PubMed - indexed for MEDLINE] (Source: Journal of Dietary Supplements)
Source: Journal of Dietary Supplements - November 18, 2015 Category: Nutrition Tags: J Diet Suppl Source Type: research

Aqueous extraction of pectin from sour orange peel and its preliminary physicochemical properties.
Abstract Sour orange peel, a by-product of the fruit juice industry, was used as a source of pectin. The effects of temperature (75-95°C), time (30-90min), and liquid-solid ratio (20-40 v/w) were investigated on yield, methoxylation degree (DE), and galacturonic acid content using a Box-Behnken design and response surface methodology. The highest extraction yield (17.95±0.3%) was obtained at temperature of 95°C, time of 90min, and liquid-solid ratio of 25 (v/w). The DE values for the pectin ranged from 17% to 30.5%, indicating that the pectin was low in methoxyle. The emulsifying activity of pectin extr...
Source: International Journal of Biological Macromolecules - November 5, 2015 Category: Biochemistry Authors: Hosseini SS, Khodaiyan F, Yarmand MS Tags: Int J Biol Macromol Source Type: research

Effect of Encapsulated Bitter Orange Peel Extract and BHT on the Quality of Common Carp Fillet during Refrigerated Storage
Authors: Hasani, Omid / Javadian, Seyed Rohollah (Source: International Journal of Food Engineering)
Source: International Journal of Food Engineering - October 30, 2015 Category: Food Science Source Type: research

Molecules, Vol. 20, Pages 18620-18660: A Systematic Review of the Anxiolytic-Like Effects of Essential Oils in Animal Models
The clinical efficacy of standardized essential oils (such as Lavender officinalis), in treating anxiety disorders strongly suggests that these natural products are an important candidate source for new anxiolytic drugs. A systematic review of essential oils, their bioactive constituents, and anxiolytic-like activity is conducted. The essential oil with the best profile is Lavendula angustifolia, which has already been tested in controlled clinical trials with positive results. Citrus aurantium using different routes of administration also showed significant effects in several animal models, and was corroborated by differ...
Source: Molecules - October 14, 2015 Category: Chemistry Authors: Damião de SousaPalloma HocayenLuciana AndradeRoberto Andreatini Tags: Review Source Type: research

Flavonoids of Korean Citrus aurantium L. Induce Apoptosis via Intrinsic Pathway in Human Hepatoblastoma HepG2 Cells
Korean Citrus aurantium L. has long been used as a medicinal herb for its anti‐inflammatory, antioxidant, and anticancer properties. The present study investigates the anticancer role of flavonoids extracted from C. aurantium on human hepatoblastoma cell, HepG2. The Citrus flavonoids inhibit the proliferation of HepG2 cells in a dose‐dependent manner. This result was consistent with the in vivo xenograft results. Apoptosis was detected by cell morphology, cell cycle analysis, and immunoblot. Flavonoids decreased the level of pAkt and other downstream targets of phosphoinositide‐3‐kinase/Akt pathway – P‐4EBP1 ...
Source: Phytotherapy Research - October 6, 2015 Category: Biochemistry Authors: Seung Hwan Lee, Silvia Yumnam, Gyeong Eun Hong, Suchismita Raha, Venu Venkatarame Gowda Saralamma, Ho Jeong Lee, Jeong Doo Heo, Sang Joon Lee, Won‐Sup Lee, Eun‐Hee Kim, Hyeon Soo Park, Gon Sup Kim Tags: Research Article Source Type: research

GC-FID/MS Profiling of Supercritical CO2 Extracts of Peels from Citrus aurantium, C. sinensis cv. Washington navel, C. sinensis cv. Tarocco and C. sinensis cv. Doppio Sanguigno from Dubrovnik Area (Croatia).
Authors: Jerković I, Drulžić J, Marijanović Z, Gugić M, Jokić S, Roje M Abstract The peels of Citrus aurantium L. and Citrus sinensis Osbeck cultivars from the Dubrovnik region (south Croatia) were extracted by supercritical CO2 at 40 degrees C and 10 MPa at 1.76 kg/h to obtain enriched extracts in comparison with simple pressing of the peels. The extracts were analyzed in detail by gas chromatography and mass spectrometry (GC-FID/MS). Relevant similarities among the peel oil compositions of C. aurantium and C. sinensis cultivars were found with limonene predominance (up to 54.3%). The principal oxyg...
Source: Natural Product Communications - September 30, 2015 Category: Biochemistry Tags: Nat Prod Commun Source Type: research

Properties and limits of some essential oils: chemical characterisation, antimicrobial activity, interaction with antibiotics and cytotoxicity.
This study aims to evaluate in vitro the antimicrobial activity of: Mirtus communis, Coriandrum sativum, Pelargonium capitatum, Cuminum cyminum, Ocimum basilicum, Citrus aurantium amara, Cymbopogon. winterianus, Cymbopogon martini, Salvia sclarea, Melaleuca alternifolia and Mentha suaveolens essential oils on bacteria and fungi, in relation to their chemical composition. The potential interaction of M. alternifolia (TTO), C. sativum (CDO) and M. suaveolens (EOMS) essential oils when used in combination with gentamicin and fluconazole has been evaluated. The results obtained showed a synergic effect on some bacteria and fun...
Source: Natural Product Research - September 23, 2015 Category: Biochemistry Authors: Scazzocchio F, Garzoli S, Conti C, Leone C, Renaioli C, Pepi F, Angiolella L Tags: Nat Prod Res Source Type: research