Mechanism insights into the pleiotropic effects of nobiletin as a potential therapeutic agent on non-alcoholic fatty liver disease (NAFLD)
Biomed Pharmacother. 2024 Feb 23;173:116322. doi: 10.1016/j.biopha.2024.116322. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases and is emerging as one of the fastest-growing causes of liver-related deaths worldwide. It is necessary to find strategies to effectively prevent and treat NAFLD, as no definitive drug has been approved. Nobiletin (NOB) is the critical active ingredient of Chinese herbal medicines such as Citrus aurantium and Citri Reticulatae Pericarpium, which have anti-inflammatory, antioxidant, lipid regulating, and insulin resistance regulating ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - February 24, 2024 Category: Drugs & Pharmacology Authors: Qiqi Ran Qianrong Gan Ye Zhu Li Song Longyu Shen Xinyi Duan Xinyun Zhu Wei Huang Source Type: research
Mechanism insights into the pleiotropic effects of nobiletin as a potential therapeutic agent on non-alcoholic fatty liver disease (NAFLD)
Biomed Pharmacother. 2024 Feb 23;173:116322. doi: 10.1016/j.biopha.2024.116322. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases and is emerging as one of the fastest-growing causes of liver-related deaths worldwide. It is necessary to find strategies to effectively prevent and treat NAFLD, as no definitive drug has been approved. Nobiletin (NOB) is the critical active ingredient of Chinese herbal medicines such as Citrus aurantium and Citri Reticulatae Pericarpium, which have anti-inflammatory, antioxidant, lipid regulating, and insulin resistance regulating ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - February 24, 2024 Category: Drugs & Pharmacology Authors: Qiqi Ran Qianrong Gan Ye Zhu Li Song Longyu Shen Xinyi Duan Xinyun Zhu Wei Huang Source Type: research
Variation of the essential oil components of Citrus aurantium leaves upon using different distillation techniques and evaluation of their antioxidant, antidiabetic, and neuroprotective effect against Alzheimer ’s disease
Citrus fruit essential oil is considered one of the widely studied essential oils while its leaves attract less attention although being rich in nearly the same composition as the peel and flowers. The leaves ... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - February 2, 2024 Category: Complementary Medicine Authors: Esraa A. Elhawary, Nilofar Nilofar, Gokhan Zengin and Omayma A. Eldahshan Tags: Research Source Type: research
The effectiveness of aromatherapy in the management of labor pain: A meta-analysis
Eur J Obstet Gynecol Reprod Biol X. 2023 Oct 18;20:100255. doi: 10.1016/j.eurox.2023.100255. eCollection 2023 Dec.ABSTRACTOne non-pharmacological method that can be used to safely and without negative side effects is aromatherapy. This meta-analysis study was carried out to assess the effectiveness of aromatherapy in the treatment of labor pain. The analysis included 14 randomized controlled trials of aromatherapy interventions for labor pain. In the studies, it was observed that aromatherapy was applied through massage and inhalation using oils such as lavender, jasmine, rose, chamomile, bitter orange, and boswellia. In t...
Source: Reproductive Biology - November 13, 2023 Category: Reproduction Medicine Authors: Atike Kaya Havva Ye şildere Sağlam Engin Karada ğ Elif G ürsoy Source Type: research
The effectiveness of aromatherapy in the management of labor pain: A meta-analysis
Eur J Obstet Gynecol Reprod Biol X. 2023 Oct 18;20:100255. doi: 10.1016/j.eurox.2023.100255. eCollection 2023 Dec.ABSTRACTOne non-pharmacological method that can be used to safely and without negative side effects is aromatherapy. This meta-analysis study was carried out to assess the effectiveness of aromatherapy in the treatment of labor pain. The analysis included 14 randomized controlled trials of aromatherapy interventions for labor pain. In the studies, it was observed that aromatherapy was applied through massage and inhalation using oils such as lavender, jasmine, rose, chamomile, bitter orange, and boswellia. In t...
Source: Reproductive Biology - November 13, 2023 Category: Reproduction Medicine Authors: Atike Kaya Havva Ye şildere Sağlam Engin Karada ğ Elif G ürsoy Source Type: research
Molecules, Vol. 28, Pages 7251: Biological Activities of Citrus aurantium Leaf Extract by Optimized Ultrasound-Assisted Extraction
In conclusion, our CALE demonstrated potential whitening, antioxidant, antiaging, and antimicrobial activities; it was also nontoxic and easily absorbed into the skin as well as inexpensive to produce. Therefore, it has potential applications in various industries. (Source: Molecules)
Source: Molecules - October 24, 2023 Category: Chemistry Authors: Guey-Horng Wang Chun-Ta Huang Hsiu-Ju Huang Chi-Hsiang Tang Ying-Chien Chung Tags: Article Source Type: research
Viruses, Vol. 15, Pages 2037: Minor Variants of Orf1a, p33, and p23 Genes of VT Strain Citrus Tristeza Virus Isolates Show Symptomless Reactions on Sour Orange and Prevent Superinfection of Severe VT Isolates
o F. Catara
The control of tristeza quick decline (QD) of citrus is based on the use of rootstocks that are tolerant or resistant to the Citrus tristeza virus (CTV), but some of them show bio-agronomic limits. The application of cross-protection (CP) has been insufficiently explored. The present study examined the possibility of QD control by cross-protection (CP) following reports showing the dependence of the CP strategy on the close genetic relationships between the protective and challenging CTV isolates. Taking advantage of deep sequencing technologies, we located six naturally infected trees harboring no-seedling...
Source: Viruses - September 30, 2023 Category: Virology Authors: Grazia Licciardello Giuseppe Scuderi Marcella Russo Marina Bazzano Moshe Bar-Joseph Antonino F. Catara Tags: Article Source Type: research
Molecules, Vol. 28, Pages 6231: Make the Quality Control of Essential Oils Greener: Fast Enantioselective GC-MS Analysis of Sweet and Bitter Orange as a Case Study
In this study, enantioselective gas chromatography (GC) was adopted to evaluate the quality of sweet and bitter orange essential oils, used as a case study. The analytical conditions were optimized and translated to fast GC to evaluate the impact of this approach on the environmental footprint of the analyses. The greenness of fast GC, compared with conventional GC, was quantitatively evaluated using a dedicated metric tool (AGREE), and important improvements have been calculated. The developed methods were applied to a set of commercial essential oils, and the data about the enantiomeric composition and relative percentag...
Source: Molecules - August 24, 2023 Category: Chemistry Authors: Gaia Bechis Manuel A. Minteguiaga Barbara Sgorbini Arianna Marengo Patrizia Rubiolo Cecilia Cagliero Tags: Article Source Type: research
Metabolic profiling of the flower of Citrus aurantium L. var. amara Engl. in rats using ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight tandem mass spectrometry with data mining strategy
CONCLUSIONS: Collectively, this present study would be conducive to the discovery of active ingredients of FCAVA for the treatment of obesity and the development of quality control of FCAVA.PMID:37580848 | DOI:10.1002/rcm.9607 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - August 14, 2023 Category: Chemistry Authors: Huixian Zhou Xinxin Huang Ting Tan Yun Luo Source Type: research
Metabolic profiling of the flower of Citrus aurantium L. var. amara Engl. in rats using ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight tandem mass spectrometry with data mining strategy
CONCLUSIONS: Collectively, this present study would be conducive to the discovery of active ingredients of FCAVA for the treatment of obesity and the development of quality control of FCAVA.PMID:37580848 | DOI:10.1002/rcm.9607 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - August 14, 2023 Category: Chemistry Authors: Huixian Zhou Xinxin Huang Ting Tan Yun Luo Source Type: research
Molecules, Vol. 28, Pages 5057: Comparison of Chemical Compositions and Antioxidant Activities for the Immature Fruits of Citrus changshan-huyou Y.B. Chang and Citrus aurantium L.
i Yin
Yiping Ye
Quzhou Aurantii Fructus (QAF), the dried immature fruit of Citrus changshan-huyou Y.B. Chang, is similar to Aurantii Fructus (AF), the dried immature fruit of Citrus aurantium L. or its cultivars, in terms of composition, pharmacological action, and appearance. However, potential chemical markers to distinguish QAF from AF remain unknown owing to the lack of a comprehensive systematic chemical comparison aligned with discriminant analysis. To achieve a better understanding of the differences in their composition, this study aimed to identify the basic chemical compounds in QAF (n = 42) and AF (n = 8) ...
Source: Molecules - June 28, 2023 Category: Chemistry Authors: Qixin Zhang Wenying Song Guanqi Tao Qin Li Lixia Wang Wenkang Huang Lijuan Gao Lai Yin Yiping Ye Tags: Article Source Type: research
Potential bio-functional properties of < em > Citrus aurantium < /em > L. leaf: chemical composition, antiviral activity on herpes simplex virus type-1, antiproliferative effects on human lung and colon cancer cells and oxidative protection
This study examined the antioxidant, anticancer and antiviral properties of the methanolic extracts from bigarade (Citrus aurantium L.) leaves at two development stages. Ferulic acid, naringin and naringenin were the principal phenolic components of young and old leaves. The highest total antioxidant capacity was obtained in young leaf extracts (YLE). These latter also exhibited the highest antiradical DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) activities, while the highest iron chelating and reducing power activities were observed in old leaf extracts (OLE). The ...
Source: Herpes - April 8, 2023 Category: Infectious Diseases Authors: Houda Mejri Wissem Aidi Wannes Faouzia Haddada Mahjoub Majdi Hammami Catherine Dussault Jean Legault Moufida Saidani-Tounsi Source Type: research
Potential bio-functional properties of < em > Citrus aurantium < /em > L. leaf: chemical composition, antiviral activity on herpes simplex virus type-1, antiproliferative effects on human lung and colon cancer cells and oxidative protection
This study examined the antioxidant, anticancer and antiviral properties of the methanolic extracts from bigarade (Citrus aurantium L.) leaves at two development stages. Ferulic acid, naringin and naringenin were the principal phenolic components of young and old leaves. The highest total antioxidant capacity was obtained in young leaf extracts (YLE). These latter also exhibited the highest antiradical DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) activities, while the highest iron chelating and reducing power activities were observed in old leaf extracts (OLE). The ...
Source: Herpes - April 8, 2023 Category: Infectious Diseases Authors: Houda Mejri Wissem Aidi Wannes Faouzia Haddada Mahjoub Majdi Hammami Catherine Dussault Jean Legault Moufida Saidani-Tounsi Source Type: research
Potential bio-functional properties of < em > Citrus aurantium < /em > L. leaf: chemical composition, antiviral activity on herpes simplex virus type-1, antiproliferative effects on human lung and colon cancer cells and oxidative protection
This study examined the antioxidant, anticancer and antiviral properties of the methanolic extracts from bigarade (Citrus aurantium L.) leaves at two development stages. Ferulic acid, naringin and naringenin were the principal phenolic components of young and old leaves. The highest total antioxidant capacity was obtained in young leaf extracts (YLE). These latter also exhibited the highest antiradical DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) activities, while the highest iron chelating and reducing power activities were observed in old leaf extracts (OLE). The ...
Source: Cancer Control - April 8, 2023 Category: Cancer & Oncology Authors: Houda Mejri Wissem Aidi Wannes Faouzia Haddada Mahjoub Majdi Hammami Catherine Dussault Jean Legault Moufida Saidani-Tounsi Source Type: research
Potential bio-functional properties of Citrus aurantium L. leaf: chemical composition, antiviral activity on herpes simplex virus type-1, antiproliferative effects on human lung and colon cancer cells and oxidative protection
. (Source: International Journal of Environmental Health Research)
Source: International Journal of Environmental Health Research - April 8, 2023 Category: Environmental Health Authors: Houda MejriWissem Aidi WannesFaouzia Haddada MahjoubMajdi HammamiCatherine DussaultJean LegaultMoufida Saidani-Tounsia Laboratory of Aromatic and Medicinal Plants, Biotechnology Center in Borj-Cedria Technopole, Hammam-lif, Tunisiab Laboratoire LASEVE, Un Source Type: research
