“Drying effect” of fructus aurantii components and the mechanism of action based on network pharmacology and in vitro pharmacodynamic validation
Conclusion: Four components of FA (tangeretin, sinensetin, chrysin, 5-Demethylmobiletin) were closely related to the Janus kinase-signal transducer and activator of transcription-3 (JAK-STAT3), PI3K-AKT, and the other signaling pathways. They can regulate the protein expression of JAK2, STAT3, PI3K, lymphocyte cell-specific protein-tyrosine kinase, vascular endothelial growth factor A, and protein kinase B1, affect water metabolism in the body and, finally, result in a drying effect. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 8, 2023 Category: Drugs & Pharmacology Source Type: research
Linalool controls the viability of Escherichia coli by regulating the synthesis and modification of lipopolysaccharide, the assembly of ribosome, and the expression of substrate transporting proteins
Food Res Int. 2023 Feb;164:112337. doi: 10.1016/j.foodres.2022.112337. Epub 2022 Dec 20.ABSTRACTEscherichia coli (E. coli) is a Gram-negative bacterium and some pathogenic types may cause serious diseases, foods or food environments were the primary routes for its infection. Citrus aurantium L. var. amara Engl., a variety of sour orange, were used as a kind of non-conventional edible plant in China, but its antimicrobial activity and mechanisms were not well studied. Thus, in this study, EO from the flower of Citrus aurantium L. var. amara Engl. (CAEO) were studied as a kind of natural antimicrobial agent to control E. col...
Source: Cell Research - February 4, 2023 Category: Cytology Authors: Zhipeng Gao Sifan Jiang Weiming Zhong Ting Liu Jiajing Guo Source Type: research
The Effect of < em > Citrus aurantium < /em > on Non-Small-Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology
CONCLUSION: Citrus aurantium can participate in the treatment of NSCLC through multiple targets and pathways.PMID:36726839 | PMC:PMC9886468 | DOI:10.1155/2023/6407588 (Source: Cell Research)
Source: Cell Research - February 2, 2023 Category: Cytology Authors: Liangliang Yao Xuan Zhang Chaoming Huang Yi Cai Chunpeng Craig Wan Source Type: research
The Effect of < em > Citrus aurantium < /em > on Non-Small-Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology
CONCLUSION: Citrus aurantium can participate in the treatment of NSCLC through multiple targets and pathways.PMID:36726839 | PMC:PMC9886468 | DOI:10.1155/2023/6407588 (Source: Atherosclerosis)
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Liangliang Yao Xuan Zhang Chaoming Huang Yi Cai Chunpeng Craig Wan Source Type: research
The Effect of < em > Citrus aurantium < /em > on Non-Small-Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology
CONCLUSION: Citrus aurantium can participate in the treatment of NSCLC through multiple targets and pathways.PMID:36726839 | PMC:PMC9886468 | DOI:10.1155/2023/6407588 (Source: Biomed Res)
Source: Biomed Res - February 2, 2023 Category: Research Authors: Liangliang Yao Xuan Zhang Chaoming Huang Yi Cai Chunpeng Craig Wan Source Type: research
Prokinetic effects of < em > Citrus reticulata < /em > and < em > Citrus aurantium < /em > extract with/without < em > Bupleurum chinense < /em > using multistress-induced delayed gastric emptying models
CONCLUSIONS: These findings indicate the potential for developing combination therapy with antidepressants and prokinetics in gastrointestinal dysmotility management.PMID:36728913 | DOI:10.1080/13880209.2023.2173249 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 2, 2023 Category: Drugs & Pharmacology Authors: Yanrong Gong Xiaoxia Liang Yanting Dai Xiang Huang Qiaozhen Su Yan Ma Fenglian Chen Shuling Wang Source Type: research
The Effect of < em > Citrus aurantium < /em > on Non-Small-Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology
CONCLUSION: Citrus aurantium can participate in the treatment of NSCLC through multiple targets and pathways.PMID:36726839 | PMC:PMC9886468 | DOI:10.1155/2023/6407588 (Source: Atherosclerosis)
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Liangliang Yao Xuan Zhang Chaoming Huang Yi Cai Chunpeng Craig Wan Source Type: research
The Effect of < em > Citrus aurantium < /em > on Non-Small-Cell Lung Cancer: A Research Based on Network and Experimental Pharmacology
CONCLUSION: Citrus aurantium can participate in the treatment of NSCLC through multiple targets and pathways.PMID:36726839 | PMC:PMC9886468 | DOI:10.1155/2023/6407588 (Source: Biomed Res)
Source: Biomed Res - February 2, 2023 Category: Research Authors: Liangliang Yao Xuan Zhang Chaoming Huang Yi Cai Chunpeng Craig Wan Source Type: research
Prokinetic effects of < em > Citrus reticulata < /em > and < em > Citrus aurantium < /em > extract with/without < em > Bupleurum chinense < /em > using multistress-induced delayed gastric emptying models
CONCLUSIONS: These findings indicate the potential for developing combination therapy with antidepressants and prokinetics in gastrointestinal dysmotility management.PMID:36728913 | PMC:PMC9897790 | DOI:10.1080/13880209.2023.2173249 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 2, 2023 Category: Drugs & Pharmacology Authors: Yanrong Gong Xiaoxia Liang Yanting Dai Xiang Huang Qiaozhen Su Yan Ma Fenglian Chen Shuling Wang Source Type: research
Comparison of Aromatherapy with Citrus aurantium and Lavender on Sexual Satisfaction in Breastfeeding Women: A Randomized Controlled Trial
Breastfeeding Medicine, Ahead of Print. (Source: Breastfeeding Medicine)
Source: Breastfeeding Medicine - January 5, 2023 Category: Perinatology & Neonatology Authors: Foruzan Sharifipour Sousan Heydarpour Nader Salari Source Type: research
Novel Nanotechnological Strategies for Skin anti-aging
CONCLUSION: Recent studies show a trend of anti-aging herbal active ingredients-loaded nanoparticles, enhancing the moisturizing, antioxidant, regenerating and photoprotective activity of the skin. Suitable safety/shelf-life stability of these novel formulations is key to a successful translation to the clinic/industry.PMID:36567280 | DOI:10.2174/1389201024666221223095315 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - December 25, 2022 Category: Biotechnology Authors: Sara Pozos-Nonato Clara Luisa Dom ínguez-Delgado Kenia Areli Campos-Santander Allyson Amelia Benavides Sandy Mar ía Pacheco-Ortin Rosa Isabel Higuera-Piedrahita Guillermo Resendiz-Gonz ález Eva Mar ía Molina-Trinidad Source Type: research
Novel Nanotechnological Strategies for Skin anti-aging
CONCLUSION: Recent studies show a trend of anti-aging herbal active ingredients-loaded nanoparticles, enhancing the moisturizing, antioxidant, regenerating and photoprotective activity of the skin. Suitable safety/shelf-life stability of these novel formulations is key to a successful translation to the clinic/industry.PMID:36567280 | DOI:10.2174/1389201024666221223095315 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - December 25, 2022 Category: Biotechnology Authors: Sara Pozos-Nonato Clara Luisa Dom ínguez-Delgado Kenia Areli Campos-Santander Allyson Amelia Benavides Sandy Mar ía Pacheco-Ortin Rosa Isabel Higuera-Piedrahita Guillermo Resendiz-Gonz ález Eva Mar ía Molina-Trinidad Source Type: research
