Molecules, Vol. 24, Pages 4254: The Effects of Different Varieties of Aurantii Fructus Immaturus on the Potential Toxicity of Zhi-Zi-Hou-Po Decoction Based on Spectrum-Toxicity Correlation Analysis
This study provides a reference for the clinical, safe use of ZZHPD, and also provides a new perspective for the study of the potential toxic substances of traditional Chinese medicine compound preparations. (Source: Molecules)
Source: Molecules - November 21, 2019 Category: Chemistry Authors: Qianqian Zhang Fang Feng Tags: Article Source Type: research

Determination of Lead in Dietary Supplements by High-Resolution Continuum-Source Graphite Furnace Atomic Absorption Spectrometry with Direct Solid Sampling
Publication date: Available online 5 November 2019Source: Journal of Food Composition and AnalysisAuthor(s): Gabriela Camera Leal, Patricia Mattiazzi, Franciele Rovasi, Thaís Dal Molin, Denise Bohrer, Paulo Cícero do Nascimento, Leandro M. de Carvalho, Carine VianaAbstractA method has been developed for the determination of lead (Pb) in dietary supplements using direct solid sampling and high-resolution continuum source graphite furnace atomic absorption spectrometry. The lead concentration was determined in 74 food supplements. The zirconium (Zr) coated platform, and chemical modifiers [Pd(NO3)2 and Mg(NO3)2] were appli...
Source: Journal of Food Composition and Analysis - November 6, 2019 Category: Food Science Source Type: research

Acute p -synephrine ingestion increases whole-body fat oxidation during 1-h of cycling at Fatmax
ConclusionAcute ingestion ofp-synephrine augments fat oxidation during prolonged and constant-intensity exercise. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 4, 2019 Category: Nutrition Source Type: research

Microencapsulation of sweet orange essential oil (Citrus aurantium var. dulcis) by liophylization using maltodextrin and maltodexdrin/gelatin mixtures: Preparation, characterization, antimicrobial and antioxidant activities.
This study evaluated maltodextrin (MD) and gelatin (GEL) in different ratios (SO1, MD only; SO2, MD and GEL = 2:1; and SO3, MD and GEL = 1:1, respectively) as wall materials to microencapsulation of sweet orange essential oil (SOEO, 10% w/w). SOEO microspheres were obtained by emulsification/lyophilization and characterized regarding the microencapsulation yield and efficiency, infrared spectroscopy, ultrastructural aspects (scanning electron microscopy, SEM), thermogravimetric (TG), derivative thermogravimetry (DTG) and differential exploratory calorimetry (DSC) and bioactive properties. Yield and SOEO microencapsulation ...
Source: International Journal of Biological Macromolecules - October 25, 2019 Category: Biochemistry Authors: Susy Fernandes de Araújo J, Leite de Souza E, Ribeiro Oliveira J, Cristina Alves Gomes A, Ryan Viana Kotzebue L, Lincon da Silva Agostini D, Lomonaco Vasconcelos de Oliveira D, Elaine Mazzetto S, Leandro da Silva A, Tejo Cavalcanti M Tags: Int J Biol Macromol Source Type: research

Comparing acupressure with aromatherapy using Citrus aurantium in terms of their effectiveness in sleep quality in patients undergoing percutaneous coronary interventions: A randomized clinical trial.
CONCLUSION: The present findings provided scientific evidence for the benefits of using different methods, including acupressure, for sleep quality in patients undergoing PCIs. IRANIAN REGISTRY OF CLINICAL TRIALS NUMBER: IRCT201707248665N6. PMID: 31662239 [PubMed - as supplied by publisher] (Source: Complementary Therapies in Clinical Practice)
Source: Complementary Therapies in Clinical Practice - October 22, 2019 Category: Complementary Medicine Authors: Asgari MR, Vafaei-Moghadam A, Babamohamadi H, Ghorbani R, Esmaeili R Tags: Complement Ther Clin Pract Source Type: research

Bitter orange oil incorporated into chitosan nanoparticles: Preparation, characterization and their potential application on antioxidant and antimicrobial characteristics of white button mushroom
Publication date: Available online 27 September 2019Source: Food HydrocolloidsAuthor(s): Roghayeh Karimirad, Mahdi Behnamian, Sara DezhsetanAbstractCitrus aurantium essential oil (CAEO) at different concentrations was incorporated into chitosan nanoparticles (CSNPs) by an ionic gelation technique to enhance the antioxidant activity and control of the microbial population of Agaricus bisporus during cold storage. The physicochemical properties of nanoparticles were investigated by high resolution transmission electron microscopy (HRTEM), FTIR, and dynamic light scattering (DLS). The synthesized nanoparticles showed spherica...
Source: Food Hydrocolloids - September 28, 2019 Category: Food Science Source Type: research

Genetic, morphological and chemical investigations reveal the genetic origin of Pompia (C. medica tuberosa Risso & Poiteau) – An old endemic Sardinian citrus fruit
Publication date: Available online 11 September 2019Source: PhytochemistryAuthor(s): François Luro, Grazia Viglietti, Elodie Marchi, Gilles Costantino, Maria Grazia Scarpia, Felix Tomi, Mathieu Paoli, Franck Curk, Patrick OllitraultAbstractCitrus fruits have been introduced to the Mediterranean area from Asia for centuries and spontaneous crosses have generated several hybrid forms, some of which have had agricultural or industrial success while others have remained niche food or ornamental products, or have disappeared. Pompia (C. medica tuberosa Risso & Poiteau) is an old endemic citrus fruit from Sardinia of unknown ge...
Source: Phytochemistry - September 13, 2019 Category: Chemistry Source Type: research

Efficacy of different citrus essential oils to inhibit the growth and B1 aflatoxin biosynthesis of Aspergillus flavus.
This study investigates the efficacy of five different citrus EOs to inhibit the growth and AFB1 synthesis of A. flavus through in vitro tests for a future application in food matrices. AFB1 detection was carried out by LC-ESI-TQD analytical approach. Lemon (Citrus limon (L.) Burm. f.), bergamot (Citrus bergamia Risso), and bitter orange (Citrus aurantium L.) EOs were the most effective causing a 97.88%, 97.04%, and 96.43% reduction in mycelial growth, respectively. Sweet orange and mandarin EOs showed the lowest percentage of mycelial growth reduction. Citrus EOs showed different capacity of AFB1 inhibition (lemon > bi...
Source: Environmental Science and Pollution Research International - August 28, 2019 Category: Environmental Health Authors: Restuccia C, Oliveri Conti G, Zuccarello P, Parafati L, Cristaldi A, Ferrante M Tags: Environ Sci Pollut Res Int Source Type: research

A review of the pharmacological and therapeutic effects of auraptene
AbstractThere is a growing awareness in herbal medications as they are usually safe and devoid of significant adverse effects. Auraptene is a natural bioactive monoterpene coumarin ether and is consumed all over the world. There is growing evidence of the therapeutic benefits of auraptene. Auraptene, also known as auraptene and 7 ‐geranyloxycoumarin, is a bioactive monoterpene coumarin from Rutaceae family, which is isolated fromCitrus aurantium (Seville orange) andAegle marmelos (bael fruit). Auraptene is a highly pleiotropic molecule, which can modulate intracellular signaling pathways that control inflammation, cell g...
Source: BioFactors - August 18, 2019 Category: Biochemistry Authors: Bahram Bibak, Farzaneh Shakeri, George E. Barreto, Zakieh Keshavarzi, Thozhukat Sathyapalan, Amirhossein Sahebkar Tags: REVIEW ARTICLE Source Type: research

A Non-Enzymatic Electrochemical Sensor based on ZrO2: Cu(I) Nanosphere Modified Carbon Paste Electrode for Electro-Catalytic Oxidative detection of Glucose in raw Citrus aurantium var. sinensis
Publication date: Available online 13 July 2019Source: Food ChemistryAuthor(s): L. Parashuram, S. Sreenivasa, S. Akshatha, V. Udayakumar, S. Sandeep kumarAbstractIn this work, a sensitive and stable ZrO2-Cu(I) nanosphere mesoporous material modified non-enzymatic glucose sensor has been developed through simple, low cost chemistry.ZrO2-Cu(I) material was obtained by controlled co-precipitation method under ultra dilution conditions. Cyclic voltammetric tests were performed in order to evaluate the electrocatalytic activity ZrO2-Cu(I) modified electrode. The modified electrode showed high sensitivity, wide linear range and ...
Source: Food Chemistry - July 16, 2019 Category: Food Science Source Type: research

Citrus aurantium L. var. amara Engl. inhibited lipid accumulation in 3T3-L1 cells and Caenorhabditis elegans and prevented obesity in high-fat diet-fed mice
Publication date: Available online 14 July 2019Source: Pharmacological ResearchAuthor(s): Chun-Yan Shen, Lin Wan, Tian-Xing Wang, Jian-Guo JiangGraphical abstractAbstractNatural products with anti-obesity effects and few side effects have attracted great attention recently. Citrus aurantium L. var. amara Engl. (CAVA) is popularly consumed as an edible and medicinal resource in China. However, its anti-obesity effects were poorly understood. The anti-obesity effects of CAVA extracts were systematically evaluated using 3T3-L1 cells, Caenorhabditis elegans (C. elegans) and high fat diet (HFD)-fed mice. Flavonoid-rich (EA) ext...
Source: Pharmacological Research - July 15, 2019 Category: Drugs & Pharmacology Source Type: research

Molecules, Vol. 24, Pages 2368: Optimization of Ultrasonic-Assisted Extraction of Total Phenolics from Citrus aurantium L. Blossoms and Evaluation of Free Radical Scavenging, Anti-HMG-CoA Reductase Activities
The objective of this study was to develop an ultrasonic-assisted procedure for the extraction of total phenolics from Citrus aurantium L. blossoms (CAB) and evaluate the free radical scavenging activity and anti-HMG-CoA reductase activity of the total phenolics. In this work, a Box– Behnken design based on single-factor experiments was used to explore the optimum extraction process. Under the optimum conditions (extraction solvent 70.31% ethanol, extraction temperature 61.94 °C, extraction time 51.73 min, and liquid-to-solid ratio 35.63 mL/g), the extraction yield of total phenolics ...
Source: Molecules - June 25, 2019 Category: Chemistry Authors: Hao Hu Hou Cao Wang Guan Zhang Wang Yu Guo Tags: Article Source Type: research

Citrus aurantium Aroma for Anxiety in Patients with Acute Coronary Syndrome: A Double-Blind Placebo-Controlled Trial
The Journal of Alternative and Complementary Medicine, Ahead of Print. (Source: The Journal of Alternative and Complementary Medicine)
Source: The Journal of Alternative and Complementary Medicine - June 17, 2019 Category: Complementary Medicine Authors: Farhad Moslemi Fatemeh Alijaniha Mohsen Naseri Anoshirvan Kazemnejad Mahsa Charkhkar Mohammad Reza Heidari Source Type: research

Flavonoids from Citrus aurantium ameliorate TNBS-induced ulcerative colitis through protecting colonic mucus layer integrity.
In this study, we explored the protection effects of naringenin, nobiletin and hesperetin from Citrus aurantium on colonic mucus layer integrity. The UC mice model was induced by trinitrobenzenesulfonic acid (TNBS). Forty mg/kg/day of naringenin, nobiletin and hesperetin were administrated orally for 7 and 3 days before and after TNBS treatment. Then body weight, disease activity index (DAI) score and colon length were recorded. Colons were collected for immunofluorescence, RT-PCR and western blot assay. Lipopolysaccharide (LPS)-induced cell-co-culture system of Caco-2 and RAW264.7 cells were used to determine activities...
Source: European Journal of Pharmacology - June 16, 2019 Category: Drugs & Pharmacology Authors: He W, Liu M, Li Y, Yu H, Wang D, Chen Q, Chen Y, Zhang Y, Wang T Tags: Eur J Pharmacol Source Type: research