Komagataella pastoris KM71H modulates neuroimmune and oxidative stress parameters in animal models of depression: a proposal for a new probiotic with antidepressant-like effect
Publication date: Available online 8 July 2021Source: Pharmacological ResearchAuthor(s): Paloma T. Birmann, Angela M. Casaril, Ana Paula Pesarico, Pamela S. Caballero, Thiago Â. Smaniotto, Rafael R. Rodrigues, Ângela N. Moreira, Fabricio R. Conceição, Fernanda S.S. Sousa, Tiago Collares, Fabiana K. Seixas, Raqueli T. França, Carine D. Corcini, Lucielli Savegnago (Source: Pharmacological Research)
Source: Pharmacological Research - July 10, 2021 Category: Drugs & Pharmacology Source Type: research

Combination LSD1 and HOTAIR-EZH2 inhibition disrupts cell cycle processes and induces apoptosis in glioblastoma cells
Publication date: Available online 8 July 2021Source: Pharmacological ResearchAuthor(s): Jixing Zhao, Weili Jin, Kaikai Yi, Qixue Wang, Junhu Zhou, Yanli Tan, Can Xu, Menglin Xiao, Biao Hong, Fenfen Xu, Kailiang Zhang, Chunsheng Kang (Source: Pharmacological Research)
Source: Pharmacological Research - July 10, 2021 Category: Drugs & Pharmacology Source Type: research

Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer
Publication date: Available online 8 July 2021Source: Pharmacological ResearchAuthor(s): Sepideh Mirzaei, Mohammad Hossein Gholami, Amirhossein Zabolian, Hossein Saleki, Mahdi Vasheghani Farahani, Soodeh Hamzehlou, Fatemeh Bakhtiari Far, Seyed Omid Sharifzadeh, Saeed Samarghandian, Haroon Khan, Amir Reza Aref, Milad Ashrafizadeh, Ali Zarrabi, Gautam Sethi (Source: Pharmacological Research)
Source: Pharmacological Research - July 10, 2021 Category: Drugs & Pharmacology Source Type: research

Liver X receptors conserve the therapeutic target potential for the treatment of rheumatoid arthritis
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Chu-Tian Mai, De-Chong Zheng, Xin-zhi Li, Hua Zhou, Ying Xie (Source: Pharmacological Research)
Source: Pharmacological Research - July 10, 2021 Category: Drugs & Pharmacology Source Type: research

Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Renyikun Yuan, Wentong Zhao, Qin-Qin Wang, Jia He, Shan Han, Hongwei Gao, Yulin Feng, Shilin Yang (Source: Pharmacological Research)
Source: Pharmacological Research - July 10, 2021 Category: Drugs & Pharmacology Source Type: research

Hypoxia-inducible factor-1: Regulatory mechanisms and drug development in stroke
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Zirong Pan, Guodong Ma, Linglei Kong, Guanhua Du (Source: Pharmacological Research)
Source: Pharmacological Research - July 8, 2021 Category: Drugs & Pharmacology Source Type: research

The Role of Androgens in Women's Health and Wellbeing
Publication date: Available online 7 July 2021Source: Pharmacological ResearchAuthor(s): Vittorio E. Bianchi, Elena Bresciani, Ramona Meanti, Laura Rizzi, Robert J. Omeljaniuk, Antonio Torsello (Source: Pharmacological Research)
Source: Pharmacological Research - July 7, 2021 Category: Drugs & Pharmacology Source Type: research

Novel rapid-acting glutamatergic modulators: Targeting the synaptic plasticity in depression
Publication date: Available online 7 July 2021Source: Pharmacological ResearchAuthor(s): Ya-Ting Wang, Xiao-Le Wang, Si-Tong Feng, Nai-Hong Chen, Zhen-Zhen Wang, Yi Zhang (Source: Pharmacological Research)
Source: Pharmacological Research - July 7, 2021 Category: Drugs & Pharmacology Source Type: research

Komagataella pastoris: A new yeast probiotic for depression?
Publication date: Available online 7 July 2021Source: Pharmacological ResearchAuthor(s): Tao Yang (Source: Pharmacological Research)
Source: Pharmacological Research - July 7, 2021 Category: Drugs & Pharmacology Source Type: research

Targeting HDAC8 to ameliorate skeletal muscle differentiation in Duchenne muscular dystrophy
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Marco Spreafico, Marco Cafora, Cinzia Bragato, Daniele Capitanio, Federica Marasca, Beatrice Bodega, Clara De Palma, Marina Mora, Cecilia Gelfi, Anna Marozzi, Anna Pistocchi (Source: Pharmacological Research)
Source: Pharmacological Research - July 7, 2021 Category: Drugs & Pharmacology Source Type: research

Autophagy in vascular dementia and natural products with autophagy regulating activity
Publication date: Available online 5 July 2021Source: Pharmacological ResearchAuthor(s): Wenzhe Wang, Ou Qiao, Haixia Ji, Xinyu Zhang, Xiaoying Han, Yi Zhang, Juan Wang, Xia Li, Wenyuan Gao (Source: Pharmacological Research)
Source: Pharmacological Research - July 6, 2021 Category: Drugs & Pharmacology Source Type: research

Heteromerization between α2A adrenoceptors and different polymorphic variants of the dopamine D4 receptor determines pharmacological and functional differences. Implications for impulsive-control disorders
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Verònica Casadó-Anguera, Estefanía Moreno, Marta Sánchez-Soto, Ning Sheng Cai, Jordi Bonaventura, Patricia Homar-Ruano, Marcelo Rubinstein, Antoni Cortés, Enric I. Canela, Sergi Ferré, Vicent Casadó (Source: Pharmacological Research)
Source: Pharmacological Research - July 6, 2021 Category: Drugs & Pharmacology Source Type: research

Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy
Publication date: Available online 3 July 2021Source: Pharmacological ResearchAuthor(s): Chun-lin Zhang, Hai-ling Wang, Peng-cheng Li, Can-dong Hong, An-qi Chen, Yan-mei Qiu, Ai-ping Zeng, Yi-fan Zhou, Ya-nan Li, Bo Hu (Source: Pharmacological Research)
Source: Pharmacological Research - July 4, 2021 Category: Drugs & Pharmacology Source Type: research

Low-dose Aspirin prevents hypertension and cardiac fibrosis when thromboxane A2 is unrestrained
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Ilaria D'Agostino, Stefania Tacconelli, Annalisa Bruno, Annalisa Contursi, Luciana Mucci, Xiaoyue Hu, Yi Xie, Raja Chakraborty, Kanika Jain, Angela Sacco, Mirco Zucchelli, Raffaele Landolfi, Melania Dovizio, Lorenza Falcone, Patrizia Ballerini, John Hwa, Paola Patrignani (Source: Pharmacological Research)
Source: Pharmacological Research - July 4, 2021 Category: Drugs & Pharmacology Source Type: research

Givinostat as metabolic enhancer reverting mitochondrial biogenesis deficit in Duchenne Muscular Dystrophy
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Matteo Giovarelli, Silvia Zecchini, Giorgia Catarinella, Claudia Moscheni, Patrizia Sartori, Cecilia Barbieri, Paulina Roux-Biejat, Alessandra Napoli, Chiara Vantaggiato, Davide Cervia, Cristiana Perrotta, Emilio Clementi, Lucia Latella, Clara De Palma (Source: Pharmacological Research)
Source: Pharmacological Research - July 4, 2021 Category: Drugs & Pharmacology Source Type: research

Mastiha has efficacy in immune-mediated inflammatory diseases through a microRNA-155 Th17 dependent action
Publication date: Available online 2 July 2021Source: Pharmacological ResearchAuthor(s): Charalampia Amerikanou, Efstathia Papada, Aristea Gioxari, Ilias Smyrnioudis, Stamatia-Angeliki Kleftaki, Evdokia Valsamidou, Victoria Bruns, Rajarshi Banerjee, Maria Giovanna Trivella, Natasa Milic, Milica Medić-Stojanoska, Amalia Gastaldelli, Aimo Kannt, MASTHEALTH, George V. Dedoussis, Andriana C. Kaliora (Source: Pharmacological Research)
Source: Pharmacological Research - July 3, 2021 Category: Drugs & Pharmacology Source Type: research

Naturally-derived targeted therapy for wound healing: Beyond classical strategies
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Saeed El-Ashram, Lamia M. El-Samad, Amal A. Basha, Abeer El Wakil (Source: Pharmacological Research)
Source: Pharmacological Research - July 3, 2021 Category: Drugs & Pharmacology Source Type: research

Aducanumab for Alzheimer’s disease: a regulatory perspective
Publication date: Available online 2 July 2021Source: Pharmacological ResearchAuthor(s): Robert Nisticò, John Joseph Borg (Source: Pharmacological Research)
Source: Pharmacological Research - July 3, 2021 Category: Drugs & Pharmacology Source Type: research

The role of extracellular vesicles in regulating local and systemic inflammation in cardiovascular disease
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Lee Ohayon, Xinyi Zhang, Partha Dutta (Source: Pharmacological Research)
Source: Pharmacological Research - July 3, 2021 Category: Drugs & Pharmacology Source Type: research

Non-cytomembrane PD-L1: An atypical target for cancer
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Honggang Ying, Xiaozhen Zhang, Yi Duan, Mengyi Lao, Jian Xu, Hanshen Yang, Tingbo Liang, Xueli Bai (Source: Pharmacological Research)
Source: Pharmacological Research - July 1, 2021 Category: Drugs & Pharmacology Source Type: research

Role of epigenetic regulation in myocardial ischemia/reperfusion injury
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Keyan Wang, Yiping Li, Tingting Qiang, Jie Chen, Xiaolong Wang (Source: Pharmacological Research)
Source: Pharmacological Research - July 1, 2021 Category: Drugs & Pharmacology Source Type: research

Hepatic stellate cells role in the course of metabolic disorders development – A molecular overview
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Nabila Bourebaba, Krzysztof Marycz (Source: Pharmacological Research)
Source: Pharmacological Research - June 27, 2021 Category: Drugs & Pharmacology Source Type: research

Strategies for Reducing Non‐Communicable Diseases in Africa
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Paul Olowoyo, Femi Popoola, Joseph Yaria, Rufus Akinyemi, Mayowa Ojo Owolabi, Pasquale Maffia (Source: Pharmacological Research)
Source: Pharmacological Research - June 23, 2021 Category: Drugs & Pharmacology Source Type: research

Cancer-elicited inflammation attenuates response and outcome in tyrosine kinase inhibitor naive patients with advanced NSCLC
Publication date: Available online 19 June 2021Source: Pharmacological ResearchAuthor(s): Hou-Qun Ying, Yu-Cui Liao, Yan-Ran Luo, Gang Xiong, Ying Huang, Ruo-Wei Nie, Cui-Fen Xiong, Xue-Xin Cheng (Source: Pharmacological Research)
Source: Pharmacological Research - June 20, 2021 Category: Drugs & Pharmacology Source Type: research

Optical control of adenosine A3 receptor function in psoriasis
Publication date: Available online 19 June 2021Source: Pharmacological ResearchAuthor(s): Marc López-Cano, Ingrid Filgaira, Ernest G. Nolen, Gisela Cabré, Jordi Hernando, Dilip K. Tosh, Kenneth A. Jacobson, Concepció Soler, Francisco Ciruela (Source: Pharmacological Research)
Source: Pharmacological Research - June 19, 2021 Category: Drugs & Pharmacology Source Type: research

ULTRA LOW DOSES AND BIOLOGICAL AMPLIFICATION: Approaching Avogadro’s Number
Publication date: Available online 19 June 2021Source: Pharmacological ResearchAuthor(s): Edward J. Calabrese, James Giordano (Source: Pharmacological Research)
Source: Pharmacological Research - June 19, 2021 Category: Drugs & Pharmacology Source Type: research

Strategies for Reducing Non-Communicable Diseases in Africa
Publication date: Available online 17 June 2021Source: Pharmacological ResearchAuthor(s): Paul OLOWOYO, Femi POPOOLA, Joseph YARIA, Rufus Akinyemi, Pasquale MAFFIA, Mayowa Ojo OWOLABI (Source: Pharmacological Research)
Source: Pharmacological Research - June 18, 2021 Category: Drugs & Pharmacology Source Type: research

A structural perspective on the design of decoy immune modulators
Publication date: Available online 17 June 2021Source: Pharmacological ResearchAuthor(s): Swetha Lankipalli, Udupi A. Ramagopal (Source: Pharmacological Research)
Source: Pharmacological Research - June 18, 2021 Category: Drugs & Pharmacology Source Type: research

Differences in the Prevention and Control of Cardiovascular and Cerebrovascular Diseases
Publication date: Available online 18 June 2021Source: Pharmacological ResearchAuthor(s): Chengdi Liu, Lida Du, Shoubao Wang, Linglei Kong, Sen Zhang, Sha Li, Wen Zhang, Guanhua Du (Source: Pharmacological Research)
Source: Pharmacological Research - June 18, 2021 Category: Drugs & Pharmacology Source Type: research

Writing it right for Pharmacological Research
Publication date: Available online 16 June 2021Source: Pharmacological ResearchAuthor(s): Robert Roskoski (Source: Pharmacological Research)
Source: Pharmacological Research - June 17, 2021 Category: Drugs & Pharmacology Source Type: research

Editorial Board
Publication date: July 2021Source: Pharmacological Research, Volume 169Author(s): (Source: Pharmacological Research)
Source: Pharmacological Research - June 17, 2021 Category: Drugs & Pharmacology Source Type: research

Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Laura Beckmann, Axel Künstner, Marco L. Freschi, Gianna Huber, Ines Stölting, Saleh M. Ibrahim, Misa Hirose, Miriam Freitag, Ewan A. Langan, Urte Matschl, Christina E. Galuska, Beate Fuchs, Johannes K. Knobloch, Hauke Busch, Walter Raasch (Source: Pharmacological Research)
Source: Pharmacological Research - June 17, 2021 Category: Drugs & Pharmacology Source Type: research

Animal models to study pathogenesis and treatments of cardiac disorders in rheumatoid arthritis: advances and challenges for clinical translation
Publication date: Available online 15 June 2021Source: Pharmacological ResearchAuthor(s): Julie Kessler, Perle Totoson, Sylvie Devaux, Johnny Moretto, Daniel Wendling, Céline Demougeot (Source: Pharmacological Research)
Source: Pharmacological Research - June 16, 2021 Category: Drugs & Pharmacology Source Type: research

New frontiers against sorafenib resistance in renal cell carcinoma: from molecular mechanisms to predictive biomarkers
Publication date: Available online 15 June 2021Source: Pharmacological ResearchAuthor(s): Yu He, Yang Luo, Lan Huang, Dan Zhang, Xixi Wang, Jiayi Ji, Shufang Liang (Source: Pharmacological Research)
Source: Pharmacological Research - June 16, 2021 Category: Drugs & Pharmacology Source Type: research

The effects of vitamin D supplementation on inflammatory biomarkers in patients with abnormal glucose homeostasis: a systematic review and meta-analysis of randomized controlled trials
Publication date: Available online 11 June 2021Source: Pharmacological ResearchAuthor(s): Fatemeh Dashti, Seyed Mohammad Mousavi, Bagher Larijani, Ahmad Esmaillzadeh (Source: Pharmacological Research)
Source: Pharmacological Research - June 12, 2021 Category: Drugs & Pharmacology Source Type: research

Estrogenic Bias in T-Lymphocyte Biology: Implications for Cardiovascular Disease
Publication date: Available online 10 June 2021Source: Pharmacological ResearchAuthor(s): Rachel Rosenzweig, Sahil Gupta, Vinay Kumar, Richard J. Gumina, Shyam S. Bansal (Source: Pharmacological Research)
Source: Pharmacological Research - June 11, 2021 Category: Drugs & Pharmacology Source Type: research

Resveratrol and endothelial function: a literature review
Publication date: Available online 10 June 2021Source: Pharmacological ResearchAuthor(s): Negin Parsamanesh, Arghavan Asghari, Saeed Sardari, Aida Tasbandi, Tannaz Jamialahmadi, Suowen Xu, Amirhossein Sahebkar (Source: Pharmacological Research)
Source: Pharmacological Research - June 11, 2021 Category: Drugs & Pharmacology Source Type: research

Oncogenic viruses and chemoresistance: What do we know?
Publication date: Available online 11 June 2021Source: Pharmacological ResearchAuthor(s): Javid Sadri Nahand, Nikta Rabiei, Reza Fathazam, Mohammad Taghizadieh, Mohammad Saeid Ebrahimi, Maryam Mahjoubin-Tehran, Hossein Bannazadeh Baghi, AliReza Khatami, Mohammad Abbasi-Kolli, Hamid Reza Mirzaei, Neda Rahimian, Maryam Darvish, Hamed Mirzaei (Source: Pharmacological Research)
Source: Pharmacological Research - June 11, 2021 Category: Drugs & Pharmacology Source Type: research

Calorie restriction conferred improvement effect on long-term rehabilitation of ischemic stroke via gut microbiota
Publication date: Available online 11 June 2021Source: Pharmacological ResearchAuthor(s): Jia-Ting Huang, Yu-Qin Mao, Bing Han, Zheng-Yan Zhang, Hui-Ling Chen, Zhan-Ming Li, Chao-Yue Kong, Jia-Qi Xu, Pei-Ran Cai, Yu-Peng Zeng, Jing Zhao, Yan-ping Zhao, Li-Shun Wang (Source: Pharmacological Research)
Source: Pharmacological Research - June 11, 2021 Category: Drugs & Pharmacology Source Type: research

Metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy
Publication date: Available online 11 June 2021Source: Pharmacological ResearchAuthor(s): Shan Wang, Jia-Lei Fu, Hui-Feng Hao, Yan-Na Jiao, Ping-Ping Li, Shu-Yan Han (Source: Pharmacological Research)
Source: Pharmacological Research - June 11, 2021 Category: Drugs & Pharmacology Source Type: research

The Endocannabinoidome in Neuropsychiatry: Opportunities and Potential Risks
Publication date: Available online 11 June 2021Source: Pharmacological ResearchAuthor(s): Gerwyn Morris, Ken Walder, Stefan Kloiber, Paul Amminger, Michael Berk, Chiara C. Bortolasci, Michael Maes, Basant K. Puri, Andre F. Carvalho (Source: Pharmacological Research)
Source: Pharmacological Research - June 11, 2021 Category: Drugs & Pharmacology Source Type: research

The role of circTmeff-1 in incubation of context-induced morphine craving
Publication date: Available online 8 June 2021Source: Pharmacological ResearchAuthor(s): Hailei Yu, Bing Xie, Jingjing Zhang, Yixiao Luo, Ewa Galaj, Xiuning Zhang, Qianchao Shen, Yi Liu, Bin Cong, Di Wen, Chunling Ma (Source: Pharmacological Research)
Source: Pharmacological Research - June 9, 2021 Category: Drugs & Pharmacology Source Type: research

Brivanib alaninate inhibited dengue virus proliferation through VEGFR2/AMPK pathway
Publication date: Available online 8 June 2021Source: Pharmacological ResearchAuthor(s): Yihong Wan, Wenyu Wu, Yuanda Wan, Jiawen Zhang, Liren Li, Xiaoguang Chen, Shuwen Liu, Xingang Yao (Source: Pharmacological Research)
Source: Pharmacological Research - June 9, 2021 Category: Drugs & Pharmacology Source Type: research

The Novel FAT4 Activator Jujuboside A Suppresses NSCLC Tumorigenesis by Activating HIPPO Signaling and Inhibiting YAP Nuclear Translocation
Publication date: Available online 9 June 2021Source: Pharmacological ResearchAuthor(s): Wensheng Wang, Qiuju Huang, Yao Chen, Zhiying Huang, Yanfang Huang, Ying Wang, Xiaoxiao Qi, Zhongqiu Liu, Linlin Lu (Source: Pharmacological Research)
Source: Pharmacological Research - June 9, 2021 Category: Drugs & Pharmacology Source Type: research

Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect Anti-obesity effect of telmisartan and the gut microbiota
Publication date: Available online 9 June 2021Source: Pharmacological ResearchAuthor(s): Laura Beckmann, Axel Künstner, Marco L. Freschi, Gianna Huber, Ines Stölting, Saleh M. Ibrahim, Misa Hirose, Miriam Freitag, Ewan A. Langan, Urte Matschl, Christina E. Galuska, Beate Fuchs, Johannes K. Knobloch, Hauke Busch, Walter Raasch (Source: Pharmacological Research)
Source: Pharmacological Research - June 9, 2021 Category: Drugs & Pharmacology Source Type: research

Extracellular vesicles from patients with Acute Coronary Syndrome impact on ischemia-reperfusion injury
Publication date: Available online 7 June 2021Source: Pharmacological ResearchAuthor(s): Fabrizio D’Ascenzo, Saveria Femminò, Francesco Ravera, Filippo Angelini, Andrea Caccioppo, Luca Franchin, Alberto Grosso, Stefano Comità, Claudia Cavallari, Claudia Penna, Gaetano Maria De Ferrari, Giovanni Camussi, Pasquale Pagliaro, Maria Felice Brizzi (Source: Pharmacological Research)
Source: Pharmacological Research - June 8, 2021 Category: Drugs & Pharmacology Source Type: research

Targeting P2RX1 alleviates renal ischemia/reperfusion injury by preserving mitochondrial dynamics
Publication date: Available online 6 June 2021Source: Pharmacological ResearchAuthor(s): Shaoyong Zhuang, Shengqiang Xia, Peiqi Huang, Jiajin Wu, Junwen Qu, Ruoyang Chen, Nan Sun, Dawei Li, Haoyu Wu, Ming Zhang, Jianjun Zhang, Xiaodong Yuan, Xu Wang (Source: Pharmacological Research)
Source: Pharmacological Research - June 7, 2021 Category: Drugs & Pharmacology Source Type: research

Targeting cancer epigenetic pathways with small-molecule compounds: Therapeutic efficacy and combination therapies
Publication date: Available online 5 June 2021Source: Pharmacological ResearchAuthor(s): Yi Wang, Qiang Xie, Huidan Tan, Minru Liao, Shiou Zhu, Ling-Li Zheng, Haixia Huang, Bo Liu (Source: Pharmacological Research)
Source: Pharmacological Research - June 6, 2021 Category: Drugs & Pharmacology Source Type: research

The roles of PKC-δ and PKC-ε in myocardial ischemia/reperfusion injury
Publication date: Available online 5 June 2021Source: Pharmacological ResearchAuthor(s): Li Chen, Dazhuo Shi, Ming Guo (Source: Pharmacological Research)
Source: Pharmacological Research - June 6, 2021 Category: Drugs & Pharmacology Source Type: research

Dietary nutrients and their control of the redox bioenergetic networks as therapeutics in redox dysfunctions sustained pathologies
Publication date: August 2021Source: Pharmacological Research, Volume 170Author(s): Haripriya Kuchi Bhotla, Arun Meyyazhagan, Manikantan Pappusamy, Sungkwon Park, Vijaya Anand Arumugam, Karthika Pushparaj, Kannan RR Rengasamy, Wenchao Liu, Balamuralikrishnan Balasubramanian (Source: Pharmacological Research)
Source: Pharmacological Research - June 6, 2021 Category: Drugs & Pharmacology Source Type: research