Breast and complementary feeding in Ethiopia: new national evidence from systematic review and meta-analyses of studies in the past 10  years: reply
(Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 22, 2020 Category: Nutrition Source Type: research

Lycopene improves sperm motility and morphology: a promising agent for treating male infertility
(Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 22, 2020 Category: Nutrition Source Type: research

Reply to the letter: Lycopene improves sperm motility and morphology: a promising agent for treating male infertility
(Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 22, 2020 Category: Nutrition Source Type: research

Sarcopenia in relation to nutrition and lifestyle factors among middle-aged and older Korean adults with obesity
AbstractPurposeTo examine the prevalence of sarcopenic obesity (SO) and its association with nutrition and lifestyle factors.MethodsData from the 2008 –2011 Korea National Health and Nutrition Examination Survey for 3937 Korean individuals aged 40 years or older with obesity defined by the modified Asia–Pacific criteria (BMI ≥ 25 kg/m2) were used. Sarcopenia was defined as an appendicular skeletal muscle mass divided by weight (%) of  
Source: European Journal of Nutrition - January 21, 2020 Category: Nutrition Source Type: research

Theobromine alleviates diet-induced obesity in mice via phosphodiesterase-4 inhibition
ConclusionAltogether, the current results signifies critical role of theobromine in reducing obesity by regulation of lipid metabolism through inhibition of PDE4, indicating its potential as a major therapeutic medicinal compound. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 21, 2020 Category: Nutrition Source Type: research

Coffee consumption and breast cancer risk in the SUN project
ConclusionEven though the number of cases was low, slight indications of an inverse association between coffee consumption and breast cancer risk among postmenopausal women were observed. Further longitudinal studies are warranted to confirm this finding. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 18, 2020 Category: Nutrition Source Type: research

Fruit and vegetable intake modifies the associations between suppressor of cytokine signaling 3 genetic variants and type 2 diabetes
ConclusionsVariants ofSOCS3 gene were associated with type 2 diabetes and the associations could be modified by the F&V intake. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 11, 2020 Category: Nutrition Source Type: research

Untargeted plasma metabolomic profiles associated with overall diet in women from the SU.VI.MAX cohort
ConclusionThis study highlighted several metabolites from both host and microbial metabolism reflecting the long-term impact of the overall diet.Trial registrationSU.VI.MAX, clinicaltrials.gov NCT00272428. Registered 3 January 2006,https://clinicaltrials.gov/show/NCT00272428 (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 11, 2020 Category: Nutrition Source Type: research

Effect of a balanced Korean diet on metabolic risk factors among overweight/obese Korean adults: a randomized controlled trial
This study was to see the effects of a balanced Korean diet (BKD) on metabolic risk factors in overweight or obese Korean adults, comparing with those of a typical American diet (TAD) and a diet recommended by the 2010 Dietary Guidelines for Americans (2010DGA).MethodsThe study was designed as a randomized crossover controlled trial, in which 61 overweight or obese volunteers were divided into six groups and each consumed the BKD, 2010DGA, and TAD in a random order for 4  weeks separated by 2-week washout intervals. Anthropometric indices, blood pressure, blood lipid content, fasting blood glucose, and blood insulin l...
Source: European Journal of Nutrition - January 11, 2020 Category: Nutrition Source Type: research

Correction to: Exploring the association between whole blood Omega-3 Index, DHA, EPA, DPA, AA and n-6 DPA, and depression and self-esteem in adolescents of lower general secondary education
The original version of this article unfortunately contained a mistake. Title was incorrect. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 10, 2020 Category: Nutrition Source Type: research

Modest improvement in CVD risk markers in older adults following quinoa ( Chenopodium quinoa Willd.) consumption: a randomized-controlled crossover study with a novel food product
AbstractPurposeTo investigate the effect of consuming quinoa biscuits on markers of CVD risk over 4  weeks in free-living older adults.MethodsA randomized-controlled, double-blind crossover trial was conducted in which consenting healthy adults aged 50 –75 years (n = 40) consumed 15 g quinoa biscuits (60 g quinoa flour/100 g) or control iso–energetic biscuits (made using wheat flour) daily for 28 consecutive days (4 weeks), in addition to their normal diet. Following a 6-week washout, participants consumed the alternate biscuit for a final 4 weeks. Anthropometry ...
Source: European Journal of Nutrition - January 9, 2020 Category: Nutrition Source Type: research

Adherence to the Dutch dietary guidelines and 15-year incidence of heart failure in the EPIC-NL cohort
ConclusionIn a large Dutch population of middle-aged adults, higher adherence to the Dutch dietary guidelines was associated with lower risk of HF. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 7, 2020 Category: Nutrition Source Type: research

Egg yolk augments type 2 immunity by activating innate cells
ConclusionCo-administration of EY may promote sensitization to EW through activation of innate immune cells, such as IECs, DCs and ILC2s, that are central to the progress of allergies. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 6, 2020 Category: Nutrition Source Type: research

Food insecurity is associated with lower adherence to the Mediterranean dietary pattern among Lebanese adolescents: a cross-sectional national study
AbstractPurposeTo derive dietary patterns (DPs) of Lebanese adolescents (10 –18 years) and evaluate associations between identified DPs and household food insecurity (HFI).MethodsData on adolescents (n = 693) were drawn from a national survey conducted in 2015 on a representative sample of Lebanese households with children. In addition to a sociodemographic questionnaire, data collection included the validated Arabic-version of the Household Food Insecurity Access Scale, used to evaluate HFI. Dietary intake was assessed using a 187-item validated food frequency questionnaire. Associations between H...
Source: European Journal of Nutrition - January 3, 2020 Category: Nutrition Source Type: research

Time course of tolerance to adverse effects associated with the ingestion of a moderate dose of caffeine
This study aimed to identify and describe the time course of tolerance to the most common caffeine-induced side effects.MethodsEleven participants took part in a crossover, double-blind placebo-controlled experimental design. In one phase, participants ingested 3  mg/kg/day of caffeine for 20 days, while in another phase, they ingested a placebo. Resting heart rate and blood pressure were measured three times per week during each 20-day phase and a quantitative survey was used to categorise the magnitude of side effects.ResultsIn the pairwise comparison with the placebo, the ingestion of caffeine increased systol...
Source: European Journal of Nutrition - January 3, 2020 Category: Nutrition Source Type: research

Dietary patterns and telomere length in community-dwelling Chinese older men and women: a cross-sectional analysis
ConclusionOur findings suggest a minimal role of dietary patterns in telomere length in community-dwelling Chinese older adults. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - January 2, 2020 Category: Nutrition Source Type: research

n-3 PUFA and caloric restriction diet alters lipidomic profiles in obese men with metabolic syndrome: a preliminary open study
AbstractPurposeFor people with metabolic syndrome (MetS), altering the macronutrient composition of their diets might ameliorate metabolic abnormalities. The common method of clinical assessment only measures total lipid concentrations but ignores the individual species that contribute to these total concentrations. Thus, to predict the amelioration of MetS following caloric restriction (CR) and the intake of fish oil, we used lipidomics to investigate changes in plasma lipids and identify potential lipid metabolites.MethodsLipidomics was performed using ultra-high-performance liquid chromatography –tandem mass spect...
Source: European Journal of Nutrition - December 21, 2019 Category: Nutrition Source Type: research

Application of the  ≤ 10:1 carbohydrate to fiber ratio to identify healthy grain foods and its association with cardiometabolic risk factors
ConclusionThe  ≤ 10:1-ratio identified grain foods with higher nutritional quality and higher intakes of these foods were associated with cardiometabolic risk factors related to atherogenic dyslipidemia and insulin resistance. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 21, 2019 Category: Nutrition Source Type: research

Effect of mushroom polysaccharides from Pleurotus eryngii on obesity and gut microbiota in mice fed a high-fat diet
ConclusionsThese results provide the first evidence thatP. eryngii polysaccharides have anti-obesity and LDL cholesterol-lowering effects in obese mice through increased excretion of bile acids and lipids and altered microbiota. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 21, 2019 Category: Nutrition Source Type: research

Association of milk consumption frequency on muscle mass and strength: an analysis of three representative Korean population studies
AbstractPurposeSarcopenia is an involuntary loss of muscle mass, strength, and physical performance associated with aging. Sarcopenia contributes to adverse health outcomes. Milk contains essential amino acids important for maintaining muscle. We investigated the relationships among milk consumption frequency (MCF), muscle mass, and strength in Korean adults.MethodsWe analyzed the data from 16,173 adults in the 2008 –2011 Korean National Health and Nutrition Examination Survey (KNHANES), 13,537 adults in the 2014–2016 KNHANES, and 8254 adults in the Korean Genome and Epidemiology Study (KoGES). MCF was divided ...
Source: European Journal of Nutrition - December 19, 2019 Category: Nutrition Source Type: research

Correction to: Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study
The original version of this article unfortunately contained a mistake. A number in Table 6 has been corrected. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 19, 2019 Category: Nutrition Source Type: research

The impact of food additives, artificial sweeteners and domestic hygiene products on the human gut microbiome and its fibre fermentation capacity
ConclusionsThis study improves understanding of how additives might affect the gut microbiota composition and its fibre metabolic activity with many possible implications for human health. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 18, 2019 Category: Nutrition Source Type: research

The effect of hesperidin supplementation on metabolic profiles in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial
ConclusionsThe results indicate that hesperidin supplementation can improve metabolic abnormalities and inflammatory status in patients with MetS. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 16, 2019 Category: Nutrition Source Type: research

Adipose tissue content of alpha-linolenic acid and development of peripheral artery disease: a Danish case-cohort study
ConclusionsWe found indications of a U-shaped association between adipose tissue content of ALA and the rate of PAD, but the association was not statistically significant. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 12, 2019 Category: Nutrition Source Type: research

Dietary inflammatory index and the aging kidney in older women: a 10-year prospective cohort study
ConclusionRecommending an increased consumption of foods with a higher anti-inflammatory potential could form part of a multifaceted approach to reduce the risk of renal disease through diet and lifestyle changes. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 11, 2019 Category: Nutrition Source Type: research

Correction to: Dietary intake of total polyphenols and the risk of all-cause and specific-cause mortality in Japanese adults: the Takayama study
The original version of this article unfortunately contained a mistake. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 11, 2019 Category: Nutrition Source Type: research

Association of frequent intake of fast foods, energy drinks, or convenience food with atopic dermatitis in adolescents
ConclusionsFrequent intake of fast foods, energy drinks, and convenience food was related to the recent-diagnosed AD in adolescents. Prospective cohort and interventional studies are needed to identify causal relationships. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 10, 2019 Category: Nutrition Source Type: research

Associations between tea and coffee beverage consumption and the risk of lung cancer in the Singaporean Chinese population
ConclusionsCoffee beverage consumption was associated with higher risk of developing lung cancer. On the other hand, black tea intake was associated with lower risk of lung cancer among men in our cohort, and further studies are needed to confirm this association. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 10, 2019 Category: Nutrition Source Type: research

Trans -10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy
Conclusions10-HDA may be a promising agent for various neuroinflammation-associated diseases. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - December 9, 2019 Category: Nutrition Source Type: research

Adherence to the Mediterranean diet is associated with decreased fecal calprotectin in patients with ulcerative colitis after pouch surgery
AbstractBackgroundMediterranean diet (MED) is associated with health benefits, yet scarce data exist regarding the role of MED in inflammatory bowel diseases (IBD). Herein, we aimed to evaluate the association between MED and inflammatory markers in patients with IBD after pouch surgery.MethodsConsecutive patients after pouch surgery due to ulcerative colitis (UC) were recruited at a comprehensive pouch clinic. Adherence to MED was calculated according to MED score, ranging from 0 (low adherence) to 9 (high adherence), based on food-frequency questionnaires. Pouch behavior was defined as normal pouch (NP) or pouchitis base...
Source: European Journal of Nutrition - December 7, 2019 Category: Nutrition Source Type: research

Is salt intake reduction a universal intervention for both normotensive and hypertensive people: a case from Iran STEPS survey 2016
This study was conducted to evaluate the magnitude of the association between salt intake and BP in hypertensive and normotensive population among a nationally representative population.MethodsThe study was conducted on a nationally representative sample of 18,635 Iranian adults aged 25  years and older who participated in the STEPS survey 2016 and provided urine sample. Salt intake was estimated through spot urine sample and Tanaka equation. Multiple linear regression model in survey data analysis was used to assess the independent effect of salt intake on BP.ResultsAfter adjusting for covariates, there was a signifi...
Source: European Journal of Nutrition - December 4, 2019 Category: Nutrition Source Type: research

Association between dietary cadmium intake and early gastric cancer risk in a Korean population: a case –control study
ConclusionsFuture studies examining the causal effects of dietary cadmium intake and the consumption of cadmium-contributing foods on early gastric cancer risk in large-scale prospective cohorts are recommended. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 9, 2019 Category: Nutrition Source Type: research

Survival of L. casei DG ® ( Lactobacillus paracasei CNCMI1572) in the gastrointestinal tract of a healthy paediatric population
ConclusionsThis study showed for the first time that L. casei DG® survives the gastrointestinal transit when ingested by children with a paediatric probiotic drinkable solution containing 1  × 109 CFU, and persists in the gut up to 3  days after the end of product intake, demonstrating resistance to gastric juices, hydrolytic enzymes and bile acids. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 9, 2019 Category: Nutrition Source Type: research

Effects of vitamin D supplementation on androgens in men with low testosterone levels: a randomized controlled trial
AbstractPurposeIt has been hypothesized that vitamin D is associated with androgen levels in men. We, therefore, aimed to evaluate whether vitamin D supplementation increases serum total testosterone (TT) levels in men with low TT levels at baseline.MethodsThe Graz Vitamin D&TT-RCT is a single-center, double-blind, randomized placebo-controlled trial conducted between March 2013 and November 2017  at the endocrine outpatient clinic at the Medical University of Graz, Austria. One-hundred healthy men with serum TT levels
Source: European Journal of Nutrition - November 9, 2019 Category: Nutrition Source Type: research

Impact of a high-protein diet during lactation on milk composition and offspring in a pig model
ConclusionFrom our current study, we conclude that even a very high maternal protein intake throughout lactation has no impact on growth and health parameters of the offspring. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 9, 2019 Category: Nutrition Source Type: research

Activation of T-regulatory cells by a synbiotic may be important for its anti-inflammatory effect
(Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 9, 2019 Category: Nutrition Source Type: research

A nutrient-wide association study for risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition and the Netherlands Cohort Study
AbstractPurposeThe evidence from the literature regarding the association of dietary factors and risk of prostate cancer is inconclusive.MethodsA nutrient-wide association study was conducted to systematically and comprehensively evaluate the associations between 92 foods or nutrients and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox proportional hazard regression models adjusted for total energy intake, smoking status, body mass index, physical activity, diabetes and education were used to estimate hazard ratios and 95% confidence intervals for standardized dietary...
Source: European Journal of Nutrition - November 8, 2019 Category: Nutrition Source Type: research

Dietary intake of advanced glycation end products (AGEs) and changes in body weight in European adults
ConclusionIn this study of European adults, higher intakes of AGEs were associated with marginally greater weight gain over an average of 5  years of follow-up. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 7, 2019 Category: Nutrition Source Type: research

Pelargonidin 3-glucoside-enriched strawberry attenuates symptoms of DSS-induced inflammatory bowel disease and diet-induced metabolic syndrome in rats
ConclusionsOur study indicates that dietary P3G decreased inflammation to decrease the symptoms of IBD, and to improve cardiovascular, liver and metabolic functions in metabolic syndrome. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 7, 2019 Category: Nutrition Source Type: research

Ergogenic effects of caffeine on peak aerobic cycling power during the menstrual cycle
ConclusionCaffeine increased peak aerobic cycling power in the early follicular, preovulatory, and mid luteal phases. Thus, the ingestion of 3  mg of caffeine per kg of body mass might be considered an ergogenic aid for eumenorrheic women during all three phases of the menstrual cycle. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 5, 2019 Category: Nutrition Source Type: research

Acute p -synephrine ingestion increases whole-body fat oxidation during 1-h of cycling at Fatmax
AbstractPurposep-Synephrine, the principal alkaloid of bitter orange (Citrus aurantium), is widely used in dietary supplements for weight loss due to its purported effect of increasing fat oxidation. However, there is a paucity of scientific information about its effectiveness in enhancing fat oxidation during exercise. The aim of this investigation was to determine the effect of an acute dose ofp-synephrine on substrate oxidation during prolonged and constant intensity exercise.MethodsIn a double-blind and randomized experiment, 14 healthy subjects performed two acute experimental trials after ingesting eitherp-synephrine...
Source: European Journal of Nutrition - November 5, 2019 Category: Nutrition Source Type: research

Lower carbohydrate and higher fat intakes are associated with higher hemoglobin A1c: findings from the UK National Diet and Nutrition Survey 2008 –2016
AbstractPurposeEvidence of low-carbohydrate, high-fat diets (LCHF) for type 2 diabetes (T2DM) prevention is scarce. We investigated how carbohydrate intake relates to HbA1c and T2DM prevalence in a nationally representative survey dataset.MethodsWe analyzed dietary information (4-day food diaries) from 3234 individuals aged  ≥ 16 years, in eight waves of the UK National Diet and Nutrition Survey (2008–2016). We calculated LCHF scores (0–20, higher score indicating lower  %food energy from carbohydrate, with reciprocal higher contribution from fat) and UK Dietary Reference Value (DRV) ...
Source: European Journal of Nutrition - November 4, 2019 Category: Nutrition Source Type: research

The association between glycemic index, glycemic load, and metabolic syndrome: a systematic review and dose –response meta-analysis of observational studies
ConclusionsDietary GI was positively associated with the prevalence of MetS. However, no significant association was found between dietary GL and the prevalence of MetS. Further studies with prospective design are needed to establish potential causal relationship between dietary GI and the MetS. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 3, 2019 Category: Nutrition Source Type: research

Melatonin supplementation and pro-inflammatory mediators: a systematic review and meta-analysis of clinical trials
The objective of the present meta-analysis is to determine the direction and magnitude of melatonin supplementation effect on inflammatory biomarkers.MethodsDatabases including PubMed, Scopus, Cochran Library, Embase, and Google Scholar were searched up to April 2019. Meta-analysis was performed using random-effect model. Subgroup analysis, sensitivity analysis, and meta-regression were also carried out.ResultsThirteen eligible studies with 22 datasets with total sample size of 749 participants were included in the meta-analysis. Melatonin supplementation significantly decreased TNF- α and IL-6 levels [(WMD =&...
Source: European Journal of Nutrition - November 2, 2019 Category: Nutrition Source Type: research

Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat
ConclusionPlasma levels of MUFAs and SAFAs strongly reflect an altered hepatic fatty acid-metabolizing enzyme expression after supplementation with different dietary fats/oils. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 1, 2019 Category: Nutrition Source Type: research

Ultra-processed food consumption drives excessive free sugar intake among all age groups in Australia
ConclusionUltra-processed food consumption drives excessive free sugar intake among all age groups in Australia. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 1, 2019 Category: Nutrition Source Type: research

Polyunsaturated fatty acids and risk of Alzheimer ’s disease: a Mendelian randomization study
ConclusionsThis study did not support the hypothesis that PUFAs decrease AD risk. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 1, 2019 Category: Nutrition Source Type: research

Prevalence of inadequate intake of folate after mandatory fortification: results from the first National Dietary Survey in Brazil
ConclusionsOur data show that folate inadequacy is still prevalent in Brazil mainly in low-income groups and less developed regions. Actions need to be taken to ensure that women of childbearing age, who presented a high prevalence of inadequate folate intake, achieve the recommended daily intake of 400  µg DFEs. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - October 31, 2019 Category: Nutrition Source Type: research

Dietary intervention using (1,3)/(1,6)- β-glucan, a fungus-derived soluble prebiotic ameliorates high-fat diet-induced metabolic distress and alters beneficially the gut microbiota in mice model
ConclusionAltogether, the outcomes of this present pre-clinical animal study show β-glucan to be a promising therapeutic candidate in the treatment of HFD-induced metabolic distress. Further comprehensive research has to be conducted to brace its clinical relevance, reproducibility and efficacy for aiding human health.Graphical abstract (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - October 29, 2019 Category: Nutrition Source Type: research

Anti-obesity effect of Lactobacillus rhamnosus LS-8 and Lactobacillus crustorum MN047 on high-fat and high-fructose diet mice base on inflammatory response alleviation and gut microbiota regulation
ConclusionThese results indicated thatL. rhamnosus LS-8 andL. crustorum MN047 supplementation possessed the anti-obesity effect on the HFFD fed mice by alleviating inflammatory response and regulating gut microbiota, which further suggested that these two probiotics can be considered as an alternative dietary supplement in combination with the preventive and therapeutic strategies against obesity and related complications.Graphic abstract (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - October 28, 2019 Category: Nutrition Source Type: research