Antioxidant, anti-inflammatory and antinociceptive potential of Ternstroemia sylvatica Schltdl. & amp; Cham
Conclusions Our work confirms the value of Ternstroemia sylvatica as an important anti-inflammatory and analgesic plant, whose mechanism seems to be associated to its antioxidant effects, and supports its uses in the Mexican traditional medicine. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Efficient hepatoprotective activity of cranberry extract against CCl4-induced hepatotoxicity in Wistar albino rat model: Down-regulation of liver enzymes and strong antioxidant activity
Conclusion The resulting data evidenced that CBE exhibits promising hepatoprotective potential against the chemical induced hepatotoxicity, maintains homeostasis in liver enzymes, and can provide significant antioxidant defense against free radicals-induced oxidative stress. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Euclea undulata Thunb.: Review of its botany, ethnomedicinal uses, phytochemistry and biological activities
This study was aimed at reviewing the botany, ethnopharmacology and biological activities of E. undulata in southern Africa. Results presented in this study are based on review of literature using search engines such as Science Direct, Springerlink, Scopus, PubMed, Web of Science, BioMed Central and Google Scholar. Herbal medicine is prepared from the decoctions of the roots, bark and leaves, and extracts of these plant parts have demonstrated anticholinesterase, anti-inflammatory, antimicrobial, antimycobacterial, antiplasmodial, antioxidant and hypoglycaemic activities. Multiple classes of phytochemical compounds su...
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Evaluating the effect of Myrtus communis on programmed cell death in hydatid cyst protoscolices
Conclusion The extract of M. communis at different concentrations could increase the activity of caspases 3 and 9 and caused programmed cell death in hydatid cyst protoscolices however, this effect was significant at high concentrations of the extract. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Effect of taurine on immune function in mice with T-cell lymphoma during chemotherapy
Conclusions Taurine can effectively enhance the immune function of mice with T-cell lymphoma during chemotherapy, reduce the toxicity of chemotherapy. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Oral pharmacological treatment for patent ductus arteriosus in premature neonates with hemodynamic repercussions
Conclusions Oral indomethacin was effective for closure of the PDA in premature neonates with severe CHRs. Oral paracetamol or ibuprofen for PDA closure in premature neonates with severe CHRs and contraindications for indomethacin was ineffective. However, results in clinical improvements of neonates allowed the subsequent use of indomethacin and successful closure of the ductus. A significant reduction of diuresis occurred in neonates who were treated with indomethacin, either as a first-line treatment or after the failure of ibuprofen or paracetamol. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Influence of light intensity and water content of medium on total dendrobine of Dendrobium nobile Lindl
Conclusions In brief, the moderately strong light intensity and water content of medium from low to medium can facilitate the growth and yield of D . nobile plants, while light intensity from moderately weak to weak can enhance the dendrobine content. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Bartonella infection in asymptomatic horses and donkeys from Tuscany, Central Italy
Conclusions The detected sero-prevalence suggests a common and frequent exposure of equids living in Central Italy to bartonellae and PCR results show that Bartonella sp. infection is possible both in horses and donkeys. At the best of our knowledge, this is the first report of B. henselae infection in donkeys. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Meningococcal disease, a clinical and epidemiological review
Publication date: Available online 28 October 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Rodrigo Siqueira Batista, Andréia Patrícia Gomes, Jorge Luiz Dutra Gazineo, Paulo Sérgio Balbino Miguel, Luiz Alberto Santana, Lisa Oliveira, Mauro Geller Meningococcal disease is the acute infection caused by Neisseria meningitidis, which has humans as the only natural host. The disease is widespread around the globe and is known for its epidemical potential and high rates of lethality and morbidity. The highest number of cases of the disease is registered in the semi-arid regions of sub-Sa...
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Glypican-3-specific cytotoxic T lymphocytes induced by human leucocyte antigen-A*0201-restricted peptide effectively kill hepatocellular carcinoma cells in  vitro
Conclusions The GPC3 522–530 peptide contains antigen-determinant and its specific CTLs can effectively kill HCC in a HLA-A2-restricted and peptide-dependent manner. Our findings suggest that this peptide may be valuable for development of therapeutic vaccine. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Association of TNFA ( −308G/A), IFNG (+874 A/T) and IL-10 (−819 C/T) polymorphisms with protection and susceptibility to dengue in Brazilian population
Conclusions This research identifies the association of the IFNG (+874 A/T), TNFA (−308G/A), IL-10 (−819 C/T) genotypes as a factor for protection, susceptibility and severity to dengue. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Antioxidants: Friend or foe?
Publication date: Available online 28 October 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): R. Sarangarajan, S. Meera, R. Rukkumani, P. Sankar, G. Anuradha Reactive oxygen species are the intermediates that are formed during the normal metabolic process which are effectively neutralized by the antioxidant system of the body. Any imbalance in this neutralization process causes oxidative stress which has been implicated as one of the cause in diseases such as Alzheimer's disease, cardiovascular disorders, cancer etc. Research has enabled the use of antioxidants as therapeutic agents in the treatment of v...
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Comparative molecular docking studies of lupeol and lupenone isolated from Pueraria lobata that inhibits BACE1: Probable remedies for Alzheimer's disease
Conclusions Our results have successfully explored the molecular mechanism of lupane triterpenoids via BACE1 inhibition, suggesting that lupeol in particular could be utilized as a useful therapeutic and preventive agent to mitigate Alzheimer's disease. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Regulating effect of glycyrrhetinic acid on bronchial asthma smooth muscle proliferation and apoptosis as well as inflammatory factor expression through ERK1/2 signaling pathway
Conclusion GA can inhibit the proliferation of bronchial smooth muscle cells and reduce the expression of inflammatory factors by inhibiting the phosphorylation of ERK1/2. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Phytochemical analysis and biological activities of Hertia cheirifolia L. roots extracts
Conclusion The ethyl acetate extract was found to be selectively antioxidant and antimicrobial. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Expression of vimentin and glial fibrillary acidic protein in central nervous system development of rats
Conclusion Our data demonstrate for the first time that the expression of Vim and GFAP in the rat's CNS during development. This data may provide a foundation for the further mechanistic studies of these two main intermediate filaments during development of CNS. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Development of a mouse model of arecoline-induced oral mucosal fibrosis
Conclusions An OSF model involving mice can be rapidly induced by drinking a high-dose of arecoline. OSF angiogenic changes in mice primarily decrease and collagen accumulation is mainly collagen type I. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Rescue effects of aqueous seed extracts of Foeniculum vulgare and Carum carvi against cadmium-induced hepatic, renal and gonadal damage in female albino rats
Conclusions Both FVE and CCE could be used as efficient treatments for liver and kidney against CC intoxication. Moreover, FVE could be utilized as a potent treatment to protect and improve female fertility from cadmium intoxication. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Effects of 8-Hydroxyisocapnolactone-2-3-diol and friedelin on mast cells degranulation
Conclusion These results exhibit the promising of 8-hydroxyisocapnolactone-2-3-diol is a potential parent structure for developing a MCs stabilizer. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Antibiofilm activity of α-mangostin extracted from Garcinia mangostana L. against Staphylococcus aureus
Conclusions Our results provide evidence that the isolated AMG has inhibitory activity against biofilm formation by S. aureus, including MRSA. Thus, isolated AMG proposes a high potential to develop a novel phytopharmaceutical for the treatment of MRSA. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Pharmacological evaluation of smooth muscle relaxant and cardiac-modulation potential of Phyla nodiflora in ex-vivo and in-vivo experiments
Conclusion This study suggests the blockage of calcium channel in the smooth muscles as a pharmacological application to make usage of P . nodiflora in the management of diarrhea, asthma and hypotensive effect. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Reverse effect of curcumin on CDDP-induced drug-resistance via Keap1/p62-Nrf2 signaling in A549/CDDP cell
Conclusions The present findings demonstrate that CDDP promotes abnormal activation of Nrf2 pathway and autophagy, leading to drug resistance of A549/CDDP cell. Curcumin attenuates this process and combat drug-resistance through its potent activation on Keap1 transcription, which is essential for interplay between oxidative stress induced Nrf2 activation and autophagy/apoptosis switch. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Some pathogenic characters of paratyphoid Salmonella enterica strains isolated from poultry
Conclusion Our results show that paratyphoid Salmonella strains with several characters of pathogenicity, that may be cause of severe pathology in animals and humans, are circulating among poultry. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Faunal data and envenomation emergency first aid of cone snails (Conus spp.) in Qeshm Island, the Persian Gulf
Conclusions Envenomation can cause various symptoms ranging from minor local pain to systemic paralysis and death due to respiratory failure. We recommend an awareness programme for the seashore visiting public. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Natural compounds and extracts from Mexican medicinal plants with anti-leishmaniasis activity: An update
Publication date: Available online 2 November 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Gabriel Alfonso Gutiérrez-Rebolledo, Susan Drier-Jonas, María Adelina Jiménez-Arellanes Leishmaniasis is considered as an emerging, uncontrolled disease and is endemic in 98 countries. Annually, about 2 million cases of cutaneous and 500000 cases of visceral-type leishmaniasis are recorded and 60000 persons died from the disease. In Mexico, cutaneous leishmaniasis is known as chiclero's ulcer and is reported in 22 states, it is considered as a health problem. For its treatment, pentavalent a...
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Electrophysiological changes of autonomic cells in left ventricular outflow tract in guinea pigs with iron deficiency anemia complicated with chronic heart failure
Conclusions There are electrophysiological abnormalities of the left ventricular outflow tract in guinea pigs with iron deficiency anemia complicated with heart failure. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

An atypical case of disseminated cutaneous leishmaniasis due to Leishmania peruviana in the valleys of Ancash-Peru
In conclusion, the atypical presentation of this disease may be related to the presence of an uncommon parasite strain or host immune deficiencies. The molecular identification of the etiology for disseminated leishmaniasis, will allow a better understanding of the presentation and proper treatment, as well as associated risk factors. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Pattern of hepatitis C virus genotypes and subtypes circulating in war-stricken Khyber Pakhtunkhwa, Pakistan: Review of published literature
Publication date: Available online 7 November 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Abdul Waheed Khan, Sadia Nawab, Zeeshan Nasim, Abdul Haleem Khan, Syed Ishfaq Ahmad, Fazli Zahir, Israr Ud Din Infection due to hepatitis C virus (HCV) is a major cause of fibrosis and hepatocellular carcinoma in Pakistan. In the current review, pattern of HCV genotypes and subtypes in Khyber Pakhtunkhwa province was ascertained in light of the available literature. After thorough analysis, genotype 3 (58.27%) was determined to be the leading HCV genotype, followed by genotypes 2 (12.39%), 1 (9.54%) and 4 (0.86%...
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Polyphenolic content, in  vitro antioxidant activity and chemical composition of extract from Nephelium lappaceum L. (Mexican rambutan) husk
Conclusions Rambutan husk cultivated in Mexico is a promising source for the recovery of added value bioactive compounds with antioxidant activity, which have potential applications as bioactive antioxidant agents for the treatment of diseases. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Antimicrobial resistance and underlying mechanisms in Staphylococcus aureus isolates
Conclusions In conclusion, it was determined that the isolates were resistant to different classes of antimicrobials at varying rates and resistance was mediated by different genetic mechanisms. Therefore, continuous monitoring of resistance in S . aureus strains is necessary to control their resistance for clinically important antimicrobials. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

Bacteriocin-like inhibitory substance (BLIS) activity of Streptococcus macedonicus MBF10-2 and its synergistic action in combination with antibiotics
Conclusion Combination of some BLIS(MBF10-2) active fractions with antibiotics (ampicillin, tetracycline or kanamycin) could demonstrate synergistic activities against certain Gram-positive species. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 5, 2017 Category: Tropical Medicine Source Type: research

An overview on cardioprotective and anti-diabetic effects of thymoquinone
Publication date: Available online 9 October 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Tahereh Farkhondeh, Saeed Samarghandian, Abasalt Borji Thymoquinone (TQ), one of the active components of Nigella sativa exhibited to have many biological effects. Several beneficial effects of TQ such as its antidiabetic, antioxidant, anticancer, hypolipidemic, and anti-inflammatory activities have been recognized. The present review focuses on the findings of recent studies on the protective effects of TQ against cardiovascular diseases. In the current review, we additionally concluded that TQ may be therapeuti...
Source: Asian Pacific Journal of Tropical Medicine - October 10, 2017 Category: Tropical Medicine Source Type: research

Elevated serum prostaglandin E2 predicts the risk of infection in hepatitis B virus-related acute-on-chronic liver failure patients
Conclusions Serum PGE2 is associated with the susceptibility to secondary infections for patients with ACLF. Increased PGE2 serum levels may serve as a potential biomarker for developing infections in ACLF patients. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 8, 2017 Category: Tropical Medicine Source Type: research

Relationship between abnormal vagus nerve tension and basal ganglia cerebral infarction induced paroxysmal atrial fibrillation
Conclusion Elderly patients with basal ganglia infarction have high incidence of PAF. Sympathetic nerve damage in cerebral basal ganglia, increased vagal tension and cardiac vagal tension are the direct causes of PAF. The results indicates that the increased central vagal nerve tension mediated PAF probably is an indication of supplying sympathetic neurotransmitter or cardiac vagal denervation treatment. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 28, 2017 Category: Tropical Medicine Source Type: research

Plasmodium falciparum found in the bone marrow of a child in Manado City, East Indonesia: a case report
Publication date: Available online 23 September 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Suryadi N.N. Tatura, Stefanus Gunawan, Janno Bernadus, Sianne Sandjoto In Indonesia, there are at least 1.3 million cases of malaria each year and Plasmodium falciparum appears to be the most common Plasmodium. The finding of Plasmodium is important for the diagnosis and management of malaria. This is a case of a 4-year-and-9-month-old male who lived in Manado, East Indonesia. He presented with a prolonged fever, was pale in appearance, and was easily fatigued over the last 3 weeks. Hepato-splenomegaly was fou...
Source: Asian Pacific Journal of Tropical Medicine - September 24, 2017 Category: Tropical Medicine Source Type: research

Synergists action of piperonyl butoxide and S,S,S-tributyl phosphorotrithioate on toxicity of carbamate insecticides against Blattella germanica
Conclusions In most of these strains, resistance to bendiocarb and carbaryl is completely eliminated by DEF, showing a very high role of estraze enzymes in resistance to bendiocarb and carbaryl. But in most strains PBO does not remove the resistance because other mechanisms, such as reduced cuticle penetration and insensitivity to the acetylcholine esterase enzyme, may be involved. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 23, 2017 Category: Tropical Medicine Source Type: research

Neuron-protective effect of subanesthestic-dosage ketamine on mice of Parkinson's disease
Conclusions The subanesthestic-dosage ketamine has some protective effects on the coordinating ability of movement and cognitive ability of Parkinson's disease mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. This is probably due to that the autophagy activity of cells is activated by subanesthestic-dosage ketamine and that the neurons are protected. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 23, 2017 Category: Tropical Medicine Source Type: research

Antifungal, molluscicidal and larvicidal assessment of anemonin and Clematis flammula L. extracts against mollusc Galba truncatula, intermediate host of Fasciola hepatica in Tunisia
Conclusions This study emphasizes the important molluscicidal and antiparasitic effects of flower ethyl acetate extracts and anemonin compound as well as the considerable antifungal activities of methanolic extracts. These results improve the therapeutic virtues of C. flammula aerial part extracts. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 21, 2017 Category: Tropical Medicine Source Type: research

Comparison of hypotensive, diuretic and renal effects between cladodes of Opuntia ficus-indica and furosemide
Conclusions Gel and aqueous extract of Opuntia ficus-indica cladode have a significant diuretic effect on rats, and the lyophilized extract has a diuretic and hypotensive effect on normotensive rabbits without deterioration in renal function test. Additional studies on active ingredients are essential to pave the way for clinical studies on diuretic and hypotensive effect of the plant. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

A review of five traditionally used anti-diabetic plants of Bangladesh and their pharmacological activities
This study has focused on five plants which are Andrographis paniculata, Ageratum conyzoides, Swertia chirata, Terminalia arjuna, and Azadirachta indica to find out their traditional formulation as anti-diabetic medicine and their pharmacological activity has also been explored through literature search. The available information about traditional anti-diabetic uses of these plants and their pharmacological activities were collected from various electronic sources like Pubmed, SciFinder, Elsevier, Springer, Scopus, Scirus, Science Direct, Google Scholar and Web of Science apart from these locally available books and peer r...
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Food intake regulation by leptin: Mechanisms mediating gluconeogenesis and energy expenditure
Publication date: Available online 18 September 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Zulfia Hussain, Junaid Ali Khan Regulation of blood glucose levels and body fat is critical for survival. Leptin circulates freely in blood and controls body weight and food intake mainly through hypothalamic receptors and regulates glucose metabolism in the liver both directly through leptin receptors and indirectly via the hypothalamic receptors of central nervous system. Leptin affects food intake regulation and eventually glucose metabolism, lipometabolism, endocrine and immune functions, reproductive func...
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Giardia duodenalis infection among rural communities in Yemen: a community-based assessment of the prevalence and associated risk factors
Conclusions The study reveals that Giardia infection is still prevalent among rural communities in Yemen. The provision of clean and safe drinking water, proper sanitation, and health education regarding personal hygiene practices, particularly handwashing, as well as identifying and treating infected family members is imperative and these interventions should be considered in a strategy to control intestinal parasites among these communities in order to curtail the transmission and morbidity caused by G. duodenalis. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Neuron-protective effect of subanesthestic-dosage ketamine on mice of Parkinson ’s disease
Conclusions The subanesthestic-dosage ketamine has some protective effects on the coordinating ability of movement and cognitive ability of Parkinson's disease mice induced by 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine. This is probably due to that the autophagy activity of cells is activated by subanesthestic-dosage ketamine and that the neurons are protected. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Morphological characteristics associated with rupture risk of multiple intracranial aneurysms
Conclusions IAs located in the ICA are associated with a negative risk of rupture, while high AR (>1.01), SR1 (>1.48) or SR2 (>1.40) are risk factors for multiple IAs rupture. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Molecular and serological prevalence of Toxoplasma gondii in pregnant women and sheep in Egypt
Conclusions Consumption of under-cooked infected mutton is an important source of human infection and the combination of the two assays provide accurate and precise data during infection. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Asymptomatic dengue infection in adults of major cities of Pakistan
Conclusions The asymptomatic dengue infection is higher in cities i.e. Karachi, Islamabad and Lahore which are at risk of developing secondary dengue infections. There is a need of awareness among the public about secondary dengue infection. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 20, 2017 Category: Tropical Medicine Source Type: research

Clinical and environmental isolates of Burkholderia pseudomallei from Brazil: Genotyping and detection of virulence gene
Conclusions This was an effort to type B. pseudomallei strains from Ceará, which is important for better understanding this pathogen, contributing for the epidemiological surveillance of melioidosis in this endemic region. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 19, 2017 Category: Tropical Medicine Source Type: research

Chemical composition, antioxidant and antibacterial activities of essential oil and methanol extract of Artemisia vulgaris and Gaultheria fragrantissima collected from Nepal
Conclusions The HPLC analysis of the methanol extract of A. vulgaris shows the presence of luteolin and morin, whereas G. fragrantissima reveals the presence of rutin and a glycosylated flavonoids. Results reveal that A. vulgaris oil is the rich source of monoterpene and sesqueterpene compounds. Furthermore, A. vulgaris and G. fragrantissima are the rich source of the phenolic and flavonoids compounds and show good antioxidant and antibacterial activity. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 19, 2017 Category: Tropical Medicine Source Type: research

Synergists action of piperonyl butoxide and S,S,S-tributyl phosphorotrithioateontoxicity of carbamate insecticides against Blattella germanica
Conclusions In most of these strains, resistance to bendiocarb and carbaryl is completely eliminated by DEF, showing a very high role of estraze enzymes in resistance to bendiocarb and carbaryl. But in most strains PBO does not remove the resistance because other mechanisms, such as reduced cuticle penetration and insensitivity to the acetylcholine esterase enzyme, may be involved. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 19, 2017 Category: Tropical Medicine Source Type: research

Protective potency of Meristotropis xanthioides against nephrotoxicity in a rat model along with its antioxidant and antibacterial activities
Conclusions: Results from present study demonstrates strong pharmaceutical potential of M. xanthioides extract to apply as a new drug supplement. Graphical abstract (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - September 19, 2017 Category: Tropical Medicine Source Type: research