Bioactive constituents obtained from the fruits of Citrus aurantium

AbstractThree new compounds, citrusauranosides A (1), B (2), and C (3), along with 22 known compounds (4–25) were obtained from the 70% ethanol –water extract of the fruits ofCitrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds,14,15,17 and23 were firstly obtained fromCitrus genus, and the NMR data of17 is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result,1,4–8, and11 displayed significant inhibitory effects on contraction tension.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research