Development of a sequential injection system with online photo-cleavage coupled to SPE for spectrophotometric determination of N-nitrosoglyphosate
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): C.S. Dourado, E.S. Lins, A.C.B. DiasAbstractThe nitrosamine N-nitrosoglyphosate (NNG) is present as a minor impurity in technical-grade glyphosate (GLY), which is widely used in crops worldwide. Due to their high toxicity, regulatory agencies have established as 1.0 mg kg−1 (w/w) the maximum concentration of NNG allowed in the technical standard of glyphosate to produce commercial formulations. Considering the high similarity between the structural formulas of NNG and GLY, a flow system with online photo-cleavage coupled to solid phase...
Source: Microchemical Journal - April 19, 2019 Category: Chemistry Source Type: research

Development of two spectrophotometric methods for quantification of certain anti-depressant drug in pure, pharmaceutical formulation and application to content uniformity testing
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Noha N. Atia, Mostafa A. Marzouq, Ahmed I. Hassan, Walid E. EltoukhiAbstractTwo accurate, rapid, simple, robust and extraction-free spectrophotometric techniques were created for assay of Amisulpride (AMS) in pure and tablet preparation. The described methods have been established on the reaction of methanolic solution of AMS with 4-(dimethylamino) benzaldehyde in acidic medium which give yellow product that can be determined at λmax = 400 nm (method-I) and the reaction AMS with tetrachloro-1, 4-benzoquinone (p-Ch) which yields inte...
Source: Microchemical Journal - April 19, 2019 Category: Chemistry Source Type: research

Nitrogen and sulfur co-doped carbon dots synthesis via one step hydrothermal carbonization of green alga and their multifunctional applications
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Yuehai Li, Fengjiao Liu, Jiabai Cai, Xuguang Huang, Luxiu Lin, Ye Lin, Hui Yang, Shunxing LiAbstractCarbon dots co-doped with nitrogen and sulfur (N/S-CDs) were prepared with the model bloom-forming green alga Dunaliella salina via a one-step hydrothermal reaction, i.e., no chemicals were required. The obtained N/S-CDs with average particle size about 3.2 ± 0.5 nm exhibited great photostability, low toxicity, high water solubility, excitation-dependent emission, and enough fluorescent activity. According to the synergy effect of the...
Source: Microchemical Journal - April 17, 2019 Category: Chemistry Source Type: research

Determination of environmental H2O2 for extended periods by chemiluminescence with real-time inhibition of iron interferences
We present a chemiluminescence sequential injection (SIA) system capable of the continuous analysis of H2O2 over extended periods (48 h) by the real-time addition of an iron complexing reagent (ICR; masking compounds) which inhibits>98% of the interference caused by iron species. The measurement error based on repeat analysis of a sample within 10 min was ±2.2%, and over 48 h was ±6%. The preparation and analysis of standards, the ability for discrete and continuous sampling, and the real-time addition of the ICR to minimize chemical interference were integrated within the SIA system. Evaluation of t...
Source: Microchemical Journal - April 16, 2019 Category: Chemistry Source Type: research

Methylene blue-based distinguishing DNA conformation for colorimetric detection of silver ions
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Song Xu, Xiaojuan Chen, Xin Chen, Yong LiangAbstractA highly sensitive colorimetric sensing strategy based on the interaction between methylene blue (MB) and C-rich single-stranded DNA (ssDNA) (24C used here) has been developed for detection of Ag+. In the absence of target Ag+, the interaction between MB and 24C makes the color immediately change from blue to purple. However, specific C-Ag+-C pair forms when Ag+ ions are present in the aqueous solution containing 24C and MB, resulting in the desorption of MB from the surface of 24C into the sol...
Source: Microchemical Journal - April 16, 2019 Category: Chemistry Source Type: research

Ion pair vortex assisted-ionic liquid based dispersive liquid-liquid microextraction for selective separation and preconcentration of 4-methylimidazole from caramel colour drinks and foodstuffs prior to its spectrophotometric determination
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Nail Altunay, Ramazan GürkanAbstractIn the study, a simple, fast, easy to use, cost-effective and green analytical method was developed for the selective extraction and determination of 4-methylimidazole (4-MeI) from caramel colored drinks and foods by using vortex assisted-ionic liquid-based dispersive liquid liquid microextraction (VA-IL-DLLM) followed by spectrophotometry. The method is based on ion-pairing of the formed anionic chelate complex, AgIm(ImH)(H2N-C(CH2OH)2(CH2O)− (in fact, where the charged chelate formation and concen...
Source: Microchemical Journal - April 16, 2019 Category: Chemistry Source Type: research

Effectiveness of a new green technology for metal removal from contaminated water
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Paola Grenni, Anna Barra Caracciolo, Livia Mariani, Martina Cardoni, Cristina Riccucci, Hannan Elhaes, Medhat A. IbrahimAbstractWater pollution by heavy metals is a matter of growing concern due to their potential toxicity for biota. The development of new and cost-effective remediation strategies is a priority in this field. For this purpose, a green technology, consisting of organic waste made up of a composite of water hyacinth dry matter and sodium alginate in microsphere form, was tested for its potential to adsorb lead and cadmium in river...
Source: Microchemical Journal - April 16, 2019 Category: Chemistry Source Type: research

Application of general regression neural network and central composite design in fabrication and performance of magnetite (Fe3O4) modified carbon paste electrode for the electrochemical detection of Clomiphene
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Shabnam Mirzaei, Sajad Moradi, Hosna Ehzari, Negin Farhadian, Mohsen ShahlaeiAbstractIn this research, a novel, simple, sensitive and selective Carbon paste electrode (CPE) modified with Iron Oxide (Fe3O4) nanoparticles is constructed and used for the Voltammetric determination of Clomiphene. The synthesized Fe3O4 nanoparticles are characterized by routine methods such as scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR) and Atomic Force Microscope (AFM). Also, Clomiphene Redox behavior was examined by Different...
Source: Microchemical Journal - April 16, 2019 Category: Chemistry Source Type: research

Silver triangular nanoplates as a colorimetric probe for sensing thiols: Characterization in the interaction with structurally related thiols of different functionality
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Aleksei A. Furletov, Vladimir V. Apyari, Alexey V. Garshev, Pavel A. Volkov, Stanislava G. DmitrienkoAbstractSilver triangular nanoplates (AgTNPs) is a promising and still relatively poorly studied colorimetric probe for sensing various organic compounds. In particular, they undergo aggregation in presence of thiols due to strong interaction with SH-group. We performed characterization of label-free AgTNPs as a colorimetric probe in their interaction with thiols of different functionality. Aggregation of AgTNPs upon the action of thiols is manif...
Source: Microchemical Journal - April 14, 2019 Category: Chemistry Source Type: research

Highly sensitive determination of dopamine based on the aggregation of small-sized gold nanoparticles
In this study, a highly selective and sensitive colorimetric method is developed for the determination of dopamine (DA) based on the aggregation of small gold nanoparticles (AuNPs). It is relied upon the size-dependent aggregation behavior of AuNPs induced by DA in the absence and presence of copper ions, offering a simple and sensitive method for detection of DA. The hydroxyl groups in the adjacent dopamine molecules induce efficiently the aggregation of 5 nm AuNPs by intermolecular hydrogen bonding, which leads to a change in color, from orange red to purple. The proposed colorimetric method gives an excellent linear r...
Source: Microchemical Journal - April 14, 2019 Category: Chemistry Source Type: research

A novel stir bar sorptive-dispersive microextraction in combination with magnetically modified graphene for isolation of seven pesticides from water samples
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Katarzyna Madej, Anna Jonda, Aleksandra Borcuch, Wojciech Piekoszewski, Lucjan Chmielarz, Barbara GilAbstractA new sample preparation technique: stir bar sorptive-dispersive microextraction (SBSDμE) with magnetically modified graphene (G-Fe3O4) as the sorbent was applied to isolation of multiclass seven pesticides (boscalid, chlorpyrifos, deltamethrin, dimethenamid-P, dimoxystrobin, metazachlor and tebuconazol) from spiked water samples. Selected experimental parameters were studied, and the optimized extraction conditions were as follows: 20...
Source: Microchemical Journal - April 14, 2019 Category: Chemistry Source Type: research

Electroactive sugars, organic acids and sugar alcohol analysis in wine using anion-exchange chromatography with electrochemical detection
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): João Carlos de Souza, José Luiz da Silva, Rodrigo Monteiro Fabrão, Nelson Ramos Stradiotto, Maria Valnice Boldrin ZanoniAbstractThe present work describes an easy, rapid and sensitive alternative methodology for simultaneous detection of sugars (glucose, fructose and arabinose), organic acids (gluconic, glucuronic and glucaric acids) and sugar alcohol (arabitol) in wine samples. The method is based on high performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) at gold electrode under detecti...
Source: Microchemical Journal - April 14, 2019 Category: Chemistry Source Type: research

Chemical mixtures and autochthonous microbial community in an urbanized stretch of the River Danube
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): A. Barra Caracciolo, L. Patrolecco, P. Grenni, M. Di Lenola, N. Ademollo, J. Rauseo, L. Rolando, F. Spataro, J. Plutzer, K. Monostory, B. SperlaghAbstractRiver pollution from different sources can affect ecosystems in different ways with consequences on water quality for both biota and human health. The River Danube was selected to perform chemical and biological analyses. The river was sampled at three different points, one inside Budapest and two just outside. Water samples were collected twice in the same year (April and November 2017) in ord...
Source: Microchemical Journal - April 14, 2019 Category: Chemistry Source Type: research

Nanoparticle-assisted optical sensor for clinical diagnosis of tuberculosis
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Zongfu An, Chang-Hyun JangAbstractTuberculosis (TB) is a serious threat to human health. Although it is simple to prevent and treat TB, its prevalence is high due to the lack of facile, rapid, and low-cost diagnostic methods. In this paper, we present a liquid crystal (LC)-based on/off immunosensor (composed of two glass pieces) for the experimental as well as clinical diagnosis of TB. A variety of antigens are mixed and immobilized on the functionalized glass substrate (the bottom surface), and nanoparticle-doped LCs are arranged in an order th...
Source: Microchemical Journal - April 13, 2019 Category: Chemistry Source Type: research

Surfactant functionalisation of magnetic nanoparticles: A greener method for parabens determination in water samples by using magnetic solid phase extraction
This study demonstrated that MNP@DC193C was a promising MSPE adsorbent for the preconcentration of parabens from environmental samples. (Source: Microchemical Journal)
Source: Microchemical Journal - April 13, 2019 Category: Chemistry Source Type: research

Investigation of 8 exogenous medicines illegally added into Guangdong herbal teas by solid phase extraction and ultrahigh performance liquid chromatography-tandem mass spectrometry
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Ling Zhang, Chunhai Li, Yanping Xian, Hao Dong, Qi Chen, Qihui HuangAbstractAnti-inflammatory and antipyretic analgesic western medicine chemicals such as aspirin and antibiotics have the potential to be illegally added into Guangdong herbal teas (GHT, Guangdong Liangcha) to enhance its efficacy. The present work reports firstly a ultrahigh performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method after HLB solid phase extraction (SPE) and purification for the simultaneous analysis of 8 chemical substances including aspirin,...
Source: Microchemical Journal - April 11, 2019 Category: Chemistry Source Type: research

In-situ versus laboratory characterization of historical site in marine environment using X-ray fluorescence and Raman spectroscopy
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): F.F. Mendonça Filho, H. Morillas, H. Derluyn, M. Maguregui, D. GrégoireAbstractRaman spectroscopy and X-ray fluorescence spectrometry are powerful analytical techniques that allow for molecular and elemental analysis, respectively. Recent developments allowed for the miniaturization of equipment to an extent that in-situ experiments become available. There are many advantages in using portable instruments, but this requires sacrifices regarding the acquisition of the spectra and the quality of the analysis. How much information is ...
Source: Microchemical Journal - April 10, 2019 Category: Chemistry Source Type: research

Highly sensitive procedure for determination of Cu(II) by GF AAS using single-drop microextraction
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Thais S. Neri, Diego P. Rocha, Rodrigo A.A. Muñoz, Nivia M.M. Coelho, Alex D. BatistaAbstractA highly-sensitive method for Cu(II) determination employing single-drop microextraction (SDME) sample prior graphite-furnace atomic absorption spectrometry (GF AAS) is described. The chelating agent 1-(2-thiazolylazo)-2-naphthol was used for copper complexation and favor mass transfer to the extractor solvent drop. An accessory for mechanized injection of the single drop was developed and a better performance of the extraction system was achieved...
Source: Microchemical Journal - April 10, 2019 Category: Chemistry Source Type: research

m-Dinitrobenzene directed aggregation-induced emission enhancement of cysteine modified fluorescent copper nanoclusters
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Gaurav Hambarde, Shilpa Bothra, Yachana Upadhyay, Rati Kanta Bera, Suban K. SahooAbstractThe sensing ability of l-cysteine modified fluorescent copper nanoclusters (Cys-CuNCs) was investigated in details with various nitro-aromatics. In addition to the reported sensing analyte i.e. picric acid (PA) that quenched the fluorescence of Cys-CuNCs, the presence of m-dinitrobenzene (m-DNB) dramatically enhanced the fluorescence of Cys-CuNCs in aqueous medium (PBS buffer, pH = 9.0) among the other tested nitro-aromatics. The aggregation-induced emis...
Source: Microchemical Journal - April 10, 2019 Category: Chemistry Source Type: research

Corn-like stationary phase for solid phase microextraction prepared by electro-assisted deposition of sol-gel/silica nanoparticles composite
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Sirwan Mohammadiazar, Mehdi Maham, Fateme HasanliAbstractA novel solid phase microextraction (SPME) fiber was fabricated based on the electrophoretic and electrochemical deposition of silica nanoparticles and silicon alkoxides as sol-gel precursors. The surface of the Cu support was initially modified by a self-assembled monolayer (SAM) of (3-mercaptopropyl) trimethoxysilane (3MPTS). Then, the composite coating was electrodeposited on the modified substrate. The SEM images showed that porous and corn-like particles of composite were coated on th...
Source: Microchemical Journal - April 10, 2019 Category: Chemistry Source Type: research

Phthalic acid as complexing agent and co-disperser for analysis of zinc and cadmium at trace levels from high volumes of sample on the base of an effervescence-assisted dispersive liquid-liquid microextraction
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Saeed Mohammad Sorouraddin, Mir Ali Farajzadeh, Hossein Najafpour QarajehAbstractA green effervescence-assisted dispersive liquid-liquid microextraction based on phthalic acid as complexing agent and co-disperser performed in a narrow-bore tube has been developed for the extraction and preconcentration of zinc and cadmium from high volume of aqueous sample, followed by flame atomic absorption spectrometry. Initially phthalic acid is added to the aqueous sample to form phthalate-metal complexes. Then the sample is transferred by a syringe into a ...
Source: Microchemical Journal - April 10, 2019 Category: Chemistry Source Type: research

The study on Suaeda heteroptera Kitag, Nereis succinea and bacteria's joint bioremediation of oil-contaminated soil
In this study, a pot experiment investigated the use of N. succinea, S. heteroptera, and oil degrading bacteria as bioremediators. The changes in crude oil, petroleum hydrocarbons and the component degradation rate at different concentrations of crude oil were measured so that the removal effects of N. succinea, S. heteroptera, and oil degrading bacteria on soil crude oil contamination could be ascertained. The results show that the degradation rate for crude oil, normal hydrocarbons and PAHs in the S. heteroptera - N. succinea - oil degrading bacteria group was higher than in the S. heteroptera and S. heteroptera - oil de...
Source: Microchemical Journal - April 8, 2019 Category: Chemistry Source Type: research

A sensitive determination of tramadol using a voltammetric platform based on antimony oxide nanoparticles
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Esra Çidem, Tuğçe Teker, Mehmet AslanogluAbstractA novel voltammetric platform has been developed with nanoparticles of antimony oxide (Sb2O3NPs) and multiwalled carbon nanotubes (MWCNTs). Scanning electron microscopy (SEM), energy dispersive X-ray (EDX) and X-ray diffraction method (XRD) were used for the characterization of the novel composite material (Sb2O3NPs/MWCNTs). The proposed composite material was used for the modification of a glassy carbon electrode (GCE). The proposed modified electrode (Sb2O3NPs/MWCNTs/GCE) was appl...
Source: Microchemical Journal - April 8, 2019 Category: Chemistry Source Type: research

Simultaneous determination of metal ions by capillary electrophoresis with contactless conductivity detection and insights into the effects of BGE component
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Mengjie Tang, Jiashun Xu, Zhongqi XuAbstractA capillary electrophoresis method integrated with capacitively coupled contactless conductivity detection (CE-C4D) using lactic acid (Lac) (providing background conductivity) and β-alanine (β-Ala) (maintaining stable ionic strength) as the components of background electrolyte (BGE) was developed for the simultaneous determination of eight metal ions (Mg2+, Mn2+, Cd2+, Co2+, Pb2+, Ni2+, Zn2+, Cu2+). The effects of the concentration and composition of BGE and other CE separation conditions in ...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

NMR spectroscopy for assessing cocaine-functional monomer interactions when preparing molecularly imprinted polymers
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Juan Sánchez-González, Ángeles Peña-Gallego, Jesús Sanmartín, Ana María Bermejo, Pilar Bermejo-Barrera, Antonio Moreda-PiñeiroAbstractSynthesis of molecularly imprinted polymers (MIPs) implies a previous pre-polymerization stage in which the template (the molecule for which the MIP offers the specific recognition cavities) interacts with the adequate functional monomer, just before the addition of the cross-linker and the initiator for performing the polymerization synthesis. The recognitio...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

Anodic stripping voltammetry for direct determination of heavy metals in bovine seminal plasma using thick film modified graphite electrodes
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Tatyana V. Skiba, Hueyhuey GouAbstractThe thick-film modified graphite sensors (TMGE) as working electrodes are used for determination of heavy metals in bovine seminal plasma by anodic stripping voltammetry. The technique proposed is a very simple, express and no any sample preparation such as acid deproteinization or autoclave digestion is necessary. The sample of seminal plasma is just diluted with electrolyte solution in the analysis process. The aliquot of the sample is injected in the electrochemical cell and the analytical signal is measu...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

A new washing-free immunosensor for tumor marker detection based on functionalized Fe3O4 submicron particles
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Zhi Zhang, Yueping Guan, Guoli Xu, Chen GuoAbstractIn this submission, a novel washing-free immunosensor was designed for chemiluminescence immunoassay (CLIA) of tumor marker using human Alpha-fetoprotein (AFP) as a representative. Reactive groups were introduced on the surface of the solvothermally prepared Fe3O4 magnetic submicron particles (MSPs) and the dual-functional polyethylene glycol (PEG) linkers were modified to reduce the non-specific adsorption capacity of the particle surface and further to immobilize N-(4-aminohexyl)-N-ethylisolum...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

Deep eutectic solvent microextraction of lead(II), cobalt(II), nickel(II) and manganese(II) ions for the separation and preconcentration in some oil samples from Turkey prior to their microsampling flame atomic absorption spectrometric determination
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Mustafa Soylak, Meltem KoksalAbstractA new liquid phase microextraction method based on deep eutectic solvent microextraction was developed for separation and preconcentration of lead, cobalt, nickel and manganese from edible oil samples like sunflower oil, baby oil, trout, waste frying oil and syrup-soaked pastry oil. A choline chloride deep eutectic solvent was used for microextraction. After extraction, analytical concentrations were determined by flame atomic absorption spectrometry. Effects of analytical parameters such as type and volume o...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

Rapid and quantitative determination of urea in milk by reaction headspace gas chromatography
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Wei-Qi Xie, Kong-Xian Yu, Yi-Xian GongAbstractIn this paper, an efficient and robust technique based on reaction headspace gas chromatographic analysis for the quantification of urea in milk is presented, which is realized by measuring formed carbon dioxide from the enzymatic hydrolysis of urea under the catalysis of enzyme urease. It was observed that the headspace equilibration was finished in 40 min at 35 °C. The new technique was proved to be accurate (relative errors ≤7.17%) and precise (relative standard deviations ≤2.93%). I...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

Thioflavin T as luminescence biosensors for nucleic acid study and RNase A activity detection
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Jinya Du, Yuzhi Dong, Han Liu, Lingli Gong, Shuang Lu, Changying Yang, Yang LiAbstractAn applicable RNase assay was constructed based on strong luminescent complex between Thioflavin T (ThT) and RNA. The emission of ThT was more sensitive to RNA than to DNA, and electrostatic interaction played an important role when ThT interacted with RNA. The ThT-RNA fluorescence system displayed high specific quenching for RNase A, which originated from the specific cleavage reaction of RNA by RNase A. The quantitative detection of RNase A was built with a r...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

A simple and flexible enzymatic glucose biosensor using chitosan entrapped mesoporous carbon nanocomposite
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Palani Barathi, Balamurugan Thirumalraj, Shen-Ming Chen, Subramania AngaiahAbstractA flexible and promising amperometric glucose biosensor was reported using direct immobilization of glucose oxidase (GOx) on chitosan supported mesoporous carbon (MPC-CHT) nanocomposite. The availability of more functional groups particularly amine groups, the CHT was selected as an immobilization matrix as well as cross linker for GOx. The MPC-CHT-GOx composites were characterized well and discussed in details. The MPC-CHT-GOx modified electrode accelerates fast ...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

Copper-film electrodes for Pb(II) trace analysis and a detailed electrochemical impedance spectroscopy study
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Matjaž Finšgar, Klodian Xhanari, Barbara PetovarAbstractThe analytical performance of differently prepared in situ copper-film glassy carbon electrodes (CuFE) was compared with the bare glassy carbon electrode (GCE) for the electroanalytical determination of Pb(II) traces in a solution containing 0.1 M HCl and 0.4 M NaCl. Electrodes were prepared and validated for different accumulation potentials in order to check the influence of hydrogen evolution on the performance of the methods. The methods were first validated for limit of det...
Source: Microchemical Journal - April 6, 2019 Category: Chemistry Source Type: research

Simultaneous analysis of daclatasvir with its three organic impurities: Application in stability studies, pharmaceuticals and serum samples
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Asia Naz, Nawab Sher, Farhan Ahmed Siddiqui, Muhammad Kashif, Aurangzeb AnsariAbstractThis work describes quantification of daclatasvir in simultaneous with its three impurities. The chromatography was developed using gradient elution, where mobile phase A is composed of mixture of acetonitrile and phosphate buffer while mobile phase B is pure acetonitrile. Impurities were resolved on a C18 analytical column (4.6 × 100 mm, 5 μm) and quantified after detection at 304 nm. After successful systematic development of chromatographi...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

Presence of antibiotics in the aquatic environment in Europe and their analytical monitoring: Recent trends and perspectives
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Urszula Szymańska, Marek Wiergowski, Ireneusz Sołtyszewski, Jarosław Kuzemko, Gabriela Wiergowska, Mateusz Kacper WoźniakAbstractThe presence of antibiotics and their metabolites in the aquatic environment exerts a negative impact on all organisms. Moreover, the easy migration of these substances to drinking water may also have serious consequences for public health, such as drug resistance. Although antibiotics and their metabolites are detected in surface waters and wastewater, there are still no systemic solutions preventing environmental...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

Sensitive detection of Trifluralin in untreated human plasma samples using reduced graphene oxide modified by polyethylene imine and silver nanoparticles: A new platform on the analysis of pesticides and chemical injuries
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Mohsen Jafari, Mohammad Hasanzadeh, Ramin Karimian, Nasrin ShadjouAbstractTrifluralin is one of herbicide which is widely distributed in the human body after absorption, whose target organs can be adipose tissue, kidney, liver, adrenal gland, skin and blood. In this work, we successfully designed a new platform based on silver nanoparticles (Ag NPs) as signal amplifier and reduced graphene oxide modified by polyethylene imine (rGO-PEI) as polymeric substrate for sensitive detection and determination of Trifluralin in human plasma sample. Therefo...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

Ultrasound-assisted Ta2O5 nanoparticles and their photocatalytic and biological applications
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): G. Nagaraju, K. Karthik, M. ShashankAbstractTa2O5 nanoparticles were synthesized by ultrasound-assisted method. The prepared nanoparticles were characterized structurally by XRD, Raman and morphologically by SEM and TEM. From the XRD pattern, orthorhombic phase Ta2O5 was observed. Raman studies confirm the presence of TaO at 613 cm−1. TEM images show the average particle size of about 21 nm. Band gap of Ta2O5 nanoparticles were carried out by UV-DRS and found to be 3.12 eV. Photocatalytic activity of Ta2O5 nanoparticles have been exa...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

Simultaneous and sensitive detection of ascorbic acid in presence of dopamine using MWCNTs-decorated cobalt (II) phthalocyanine modified GCE
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Mounesh, Bhvimane Sanna Jilani, Malatesh Pari, K.R. Venugopala Reddy, K.S. LokeshAbstractThe synthesis of tetra­8­[(E)­(4­methoxybenzylidene)amino] naphthalene­1­amine cobalt (II) phthalocyanine (CoTMBANAPc) from cobalt (II) tetracarboxylic acid phthalocyanine (CoTCAPc) via amide bridge has been described for the first time. These macromolecules displayed admirable solubility in aprotic organic solvents and compound has been characterized by UV–Vis, FT-IR, 1H NMR, XRD, TGA and Mass spectroscopic methods in addition ...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

Spectrodensitometric determination of rivastigmine after vortex assisted magnetic solid phase extraction
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Fardous A. Mohamed, Pakinaz Y. Khashaba, Mohamed M. El-Wekil, Reem Y. ShahinAbstractA highly sensitive and cost-effective HPTLC method was developed for the determination of rivastigmine hydrogen tartarate (RIV) in bulk and capsules. Moreover, magnetic solid phase extraction procedure (MSPE) was performed for analysis of RIV in human plasma to preconcentrate RIV and decrease interference from plasma constituents. The magnetic nanoparticles (MNPs) were prepared by co-precipitation process and characterized by scanning electron microscope (SEM), F...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

Using image analysis to estimate the soil organic carbon content
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Pedro Augusto de Oliveira Morais, Diego Mendes de Souza, Beata Emoke Madari, Anderson da Silva Soares, Anselmo Elcana de OliveiraAbstractSoil test for organic carbon content using the Walkley-Black standard method is a laborious task that takes almost 5 working days to report the results. In order to improve lab analysis efficiency, a new analytical method using digital images is proposed. Using multivariate image analysis (MIA) soil organic carbon (SOC) contents can be determined in  0.93, between image data and SOC contents measured by the...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

A spectrophotometric procedure for sialic acid determination in milk employing a flow-batch analysis system with direct heating
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Joicy B. S. Costa, Nattany T.G. de Paula, Paulo A.B. da Silva, Gustavo C.S. de Souza, Ana Paula S. Paim, André F. LavoranteAbstractThe quantitative determination of sialic acid can indicate the addition of cheese whey to milk. This work describes an automated procedure to determine sialic acid in milk samples using a flow-batch system analysis with direct heating. The sialic acid quantification was based on a reaction between the sialic acid and acid ninhydrin producing a stable compound with maximum absorption at 470 nm. The flow-batch...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

A convenient chemiluminescence detection for bisphenol A in E-waste dismantling site based on surface charge change of cationic gold nanoparticles
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Yingying Qi, Jiahuan He, Fu-Rong Xiu, Xuan Yu, Xiang Gao, Yifan Li, Yongwei Lu, Zhiqi SongAbstractThe crude disassembling for electronic waste (E-waste) has resulted in serious pollution of the environment in dismantling site. Convenient detection of single contaminant in dismantling site is very important to evaluating environmental pollution caused by single component during dismantling process and environment supervision. Herein, a novel chemiluminescence (CL) assay was constructed to detect ubiquitous pollutant bisphenol A (BPA) in dismantli...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

An advanced technique for rapid and accurate monitoring of gaseous formaldehyde using large-volume injection interfaced with gas chromatograph/barrier discharge ionization detector (LVI/GC/BID)
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Mi-Ji Yoo, Sang-Hee Jo, Ki-Hyun KimAbstractAs a hazardous volatile organic compound (VOC), formaldehyde (FA) is found ubiquitously in both polluted and unpolluted environments. Hence, for the proper control of FA, techniques for rapid and precise quantitation of FA are in great demand. However, because of its low molecular weight and high reactivity, its quantitation generally requires complicated procedures (such as combination of sampling through 2,4-dinitrophenylhydrazine (DNPH) derivatization and detection through high-performance liquid chr...
Source: Microchemical Journal - April 5, 2019 Category: Chemistry Source Type: research

New approach for simultaneous analysis of commonly used antigout drugs by HPLC/UV method; Application in pharmaceutical and biological analysis
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Noha M. Hosny, Katherine Huddersman, Samia M. El-Gizawy, Noha N. AtiaAbstractAn innovative, simple, fast, specific and sensitive high performance liquid chromatographic method with ultraviolet detection (HPLC/UV) was established and validated for simultaneous determination of a combination of three commonly prescribed antigout drugs namely; Colchicine (CLN), Probenecid (PRD) and Febuxostat (FBX) in dosage forms and in human urine samples. GraceSmart RP C18 column was utilized for separation of the studied mixture using isocratic mode of mobile s...
Source: Microchemical Journal - April 3, 2019 Category: Chemistry Source Type: research

Experimental design methodology for optimization and robustness determination in ion pair RP-HPLC method development: Application for the simultaneous determination of metformin hydrochloride, alogliptin benzoate and repaglinide in tablets
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Marianne A. Mahrouse, Nesrine T. LamieAbstractExperimental design methodology (DOE) surpasses traditional (one variable at a time) approach in improving the chromatographic separation performance with minimum effort and resources. Since combination therapy of oral hypoglycemic drugs was generally recommended by Clinical Practice Guidelines on hypoglycemic agent therapy for treatment of type 2 diabetes mellitus, DOE was adopted in development of an ion pair RP-HPLC method for the simultaneous determination of metformin hydrochloride (MET), alogli...
Source: Microchemical Journal - April 2, 2019 Category: Chemistry Source Type: research

Glassy carbon electrode modified with blast furnace slag for electrochemical investigation of Cu2+ and Pb2+ metal ions
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Arti Mourya, Sudip K. Sinha, Bidyut MazumdarAbstractThe present work aims with electrochemical determination of non-biodegradable lead and copper metal ions using glassy carbon electrode (GCE) modified with pristine blast furnace slag (BFS). The GCE-BFS composite electrode was synthesized via the typical glassy carbon pastes with subsequent electrochemical characterization by voltammetric methods. Morphological studies were performed by scanning electron microscope (SEM) equipped with EDX elemental mapping. Surface area of the modified glassy ca...
Source: Microchemical Journal - April 2, 2019 Category: Chemistry Source Type: research

The use of Arrhenius kinetics to evaluate different hydrolytic stability of amiloride hydrochloride and cyclopenthiazide using chromatographic methods
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Mohamed H. Abdel-Hay, Marwa A.A. Ragab, Hytham M. Ahmed, Sara M. MohyeldinAbstractTwo stability-indicating assay methods, HPLC-DAD and HPTLC, for analyzing amiloride hydrochloride, AMI, and cyclopenthiazide, CYPZ, have been developed. The drugs were subjected to forced thermal, chemical and photo-degradation conditions including acidic, basic and neutral hydrolysis, oxidation, dry heat, and photolysis. The drugs were resolved from their forced-degradation products. The kinetics of degradation was studied using Arrhenius plot followed by calculat...
Source: Microchemical Journal - April 1, 2019 Category: Chemistry Source Type: research

New modified carbon based solid phase extraction sorbent prepared from wild cherry stone as natural raw material for the pre-concentration and determination of trace amounts of copper in food samples
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Bahram Ebrahimi, Sirwan Mohammadiazar, Sana ArdalanAbstractA new activated carbon (AC) adsorbent was prepared from cherry stone of native wild cherry shrub of Kurdistan as raw material. The AC was modified by acidic and microwave modification methods and applied as dispersive solid phase extraction (dSPE) sorbent. Hydrochloric (15% w/w) and nitric (32.5% w/w) acids were used to oxidize the porous surface of AC and to change its surface chemistry. Acidic functional groups on acidic modified AC (AM-AC) sample were seen in related FT-IR spectrum. A...
Source: Microchemical Journal - March 31, 2019 Category: Chemistry Source Type: research

A novel quick and highly selective “turn-on” fluorescent probe for Hg2+ and its application
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Yuehua Yuan, Lixia Guo, Zezhong Chen, Yongjun Zhu, Liheng Feng, Wei Hu, Maozhong Tian, Haiyan Wang, Feng FengAbstractIn the present work, we reported the simple synthetic strategy of fluorescent probe BAA. In order to increase the binding ability and selectivity of the probe for Hg2+, an alkynyl group was introduced on the adjacent position of the azo group of the probe. The molecular structure of BAA was characterized by 1H NMR, 13C NMR, IR, and MALDI-TOF. Spectrum analysis indicated that BAA exhibited high selective turn-on fluorescence signal...
Source: Microchemical Journal - March 31, 2019 Category: Chemistry Source Type: research

Detection oxidative degradation in lubricating oil under storage conditions using digital images and chemometrics
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Flaviana C.P. Ribeiro, Alan S. Oliveira, Alisson Araújo, Weverton Marinho, Mateus P. Schneider, Licarion Pinto, Adriano A. GomesAbstractEarly detection of the degradation process of lubricating oil caused by storage condition can prevent extensive losses for rural producers and mining companies, which operate far from urban centers and need to purchase large volumes of lubricating oil. This work concerns the development of an approach combining computer vision-based analytical methods and chemometrics tool for lubricating oil oxidation de...
Source: Microchemical Journal - March 31, 2019 Category: Chemistry Source Type: research

Wavelength dispersive X-ray fluorescence (WD-XRF) applied to speciation of sulphur in mineral supplement for cattle: Evaluation of the chemical and matrix effects
Publication date: June 2019Source: Microchemical Journal, Volume 147Author(s): Diego Victor Babos, Vinicius Câmara Costa, Edenir Rodrigues Pereira-FilhoAbstractA nondestructive method for speciation of sulphur (S), elemental sulphur and sulphate; and determination of total sulphur in mineral supplements for cattle by wavelength dispersive X-ray fluorescence (WD-XRF) spectrometry is proposed. Using direct solids analysis it was possible to perform S speciation with high analytical frequency, simplicity and precision. The intensities ratio for the different electronic transitions (S Kα1,2, S Kβ and S Kβ...
Source: Microchemical Journal - March 31, 2019 Category: Chemistry Source Type: research