What Is the Most Common Type of Cardiomyopathy?
Discussion
Barth syndrome is characterized by a dilated cardiomyopathy, proximal skeletal muscle weakness, neutropenia and short stature that usually presents at birth or soon after. It is a rare X-linked recessive disease process caused by mutations in the TAZ gene. The TAZ gene codes for tafazzin which alters cardiolipin in mitochondria. Characteristic facies can be seen especially in infancy including a tall and broad forehead, prominent chin and full cheeks, larger ears, and deep-set eyes. Most patients present at birth or soon afterwards but some may not until later in life. Life expectancy is reduced with many children dying in infancy and young childhood because of cardiomyopathy.
Myocarditis is inflammation of the myocardium that causes cardiac dysfunction. It is usually caused by infectious diseases particularly viruses, but also drugs, toxins and systemic diseases.
Causes include:
Infectious diseases
Virus
Adenovirus**
Coxsackie virus**
Cytomegalovirus
Epstein-Barr virus
Hepatitis C**
Human immunodeficiency virus
Human herpes virus 6**
Influenza
Parvovirus B-19**
Other infections
Streptococcus
Trypanosomiasis
Non-infectious causes
Idiopathic
Drug-induced hypersensitivity
Eosinophilic myocarditis
Giant cell myocarditis
Sarcoidosis
Systemic lupus erythematosus
** = most common viruses identified
Myocarditis is divided into 3 phases: acute (where muscle fibers can be lysed), subacute (where viral cell damage occurs including apoptosis, and inflammatory proc...
Source: PediatricEducation.org - Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
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