Woman whose lupus sent her into heart and kidney failure describes agonizing five-year battle
Nichole Woodward, 27, of Nebraska developed lupus suddenly five years ago, losing her hair, nearly 20lbs and going in to heart and kidney failure. Now, her autoimmune disease is at last under control. (Source: the Mail online | Health)
Source: the Mail online | Health - June 19, 2018 Category: Consumer Health News Source Type: news

Abatacept Misses the Mark in Lupus Nephritis
(MedPage Today) -- But further analyses planned because of " provocative " findings (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 19, 2018 Category: Rheumatology Source Type: news

Tattoo health warning for people with weakened immune systems
A woman with cystic fibrosis and lung transplants suffered chronic pain for three years after she had a tattoo on her thighGetting a tattoo if you have a weakened immune system could put you at risk of complications, doctors have warned. The caution comes after a woman with cystic fibrosis and lung transplants developed thigh and knee pain after having body art inked on her leg.Doctors say those taking immunosuppressant drugs should take precautions if considering body art. These medicines are often given after an organ transplant or to treat autoimmune conditions such as Crohn ’s disease, lupus or rheumatoid arthrit...
Source: Guardian Unlimited Science - June 18, 2018 Category: Science Authors: Nicola Davis Tags: Tattoos Medical research Immunology Biochemistry and molecular biology Health Cystic fibrosis Diabetes Source Type: news

Two UAB professors among nine nationally to receive lupus research grants
Two UAB researchers have received Novel Research grants from the Lupus Research Alliance.   The grants, which total $100,000 for up to three years, were awarded to Andre Ballesteros-Tato and Frances Lund. The grants are aimed toward developing targeting treatments for lupus, a complex auto-immune disorder that has widespread and varied effects throughout the body. The professors are two of nine researchers nationwide who were awarded these grants to explore lupus from many different perspectives… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - June 18, 2018 Category: Biotechnology Authors: Tyler Patchen Source Type: news

Two UAB professors among nine nationally to receive lupus research grants
Two UAB researchers have received Novel Research grants from the Lupus Research Alliance.   The grants, which total $100,000 for up to three years, were awarded to Andre Ballesteros-Tato and Frances Lund. The grants are aimed toward developing targeting treatments for lupus, a complex auto-immune disorder that has widespread and varied effects throughout the body. The professors are two of nine researchers nationwide who were awarded these grants to explore lupus from many different perspectives… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - June 18, 2018 Category: American Health Authors: Tyler Patchen Source Type: news

Rituximab Therapy in Lupus
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - June 15, 2018 Category: Orthopaedics Tags: Perspective Source Type: news

Lilly's Lupus Treatment Succeeds in Mid-Stage Trial Lilly's Lupus Treatment Succeeds in Mid-Stage Trial
Eli Lilly& Co said its drug to treat autoimmune disease lupus met the main goal of a mid-stage trial, positioning the drugmaker to begin a bigger study later this year.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 14, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

EULAR: Baricitinib Shows Promise in SLE
(MedPage Today) -- Significant clinical benefits with JAK inhibition in active lupus (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - June 14, 2018 Category: Rheumatology Source Type: news

Clinical advances in systemic lupus erythematosus
(European League Against Rheumatism) The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate exciting advances for individuals suffering from systemic lupus erythematosus (SLE). The first is a phase II clinical study of a promising oral treatment, baricitinib. The second demonstrates the effective use of shingles vaccine in SLE patients who are particularly prone to this infection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 14, 2018 Category: Infectious Diseases Source Type: news

Lilly's lupus treatment succeeds in mid-stage trial
(Reuters) - Eli Lilly& Co said its drug to treat autoimmune disease lupus met the main goal of a mid-stage trial, positioning the drugmaker to begin a bigger study later this year. (Source: Reuters: Health)
Source: Reuters: Health - June 13, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Systemic Lupus Erythematosus: 2004 Perspectives
Title: Systemic Lupus Erythematosus: 2004 PerspectivesCategory: Doctor's& Expert's views on SymptomsCreated: 11/1/2004 12:00:00 AMLast Editorial Review: 6/13/2018 2:55:09 PM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - June 13, 2018 Category: Rheumatology Source Type: news

Systemic Lupus Erythematosus 2002 Arthritis Conference Report
Title: Systemic Lupus Erythematosus 2002 Arthritis Conference ReportCategory: Doctor's& Expert's views on SymptomsCreated: 1/6/2003 12:00:00 AMLast Editorial Review: 6/13/2018 2:55:09 PM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - June 13, 2018 Category: Rheumatology Source Type: news

Low Disease Activity in Lupus Limits Damage
(MedPage Today) -- Organ damage decreased by 50% with persistent low disease activity (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - May 31, 2018 Category: Rheumatology Source Type: news

Nigeria:Experts Urge Lupus Patients to See Their Doctors Regularly
[This Day] To raise awareness and make a difference for people affected by Lupus in Nigeria, experts from Labalaba Foundation for Lupus Awareness and Advocacy have urged patients to make their rheumatologists their best friends and go for constant check up. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 24, 2018 Category: African Health Source Type: news

Experts Discuss Unique Side Effects of Immunotherapy
If you have mesothelioma and you’ve already received standard-of-care therapies, you may be considering an immunotherapy clinical trial. If you’re considering this option, a free immunotherapy teleconference is a great place to learn more. CancerCare recently hosted two one-hour education workshops featuring panels of immunotherapy experts. Part I of the teleconference presented an overview of immunotherapy. Part II of the teleconference, which is available online for free, focused exclusively on immunotherapy side effects. Understanding these issues and the role each patient plays in managing their own side ef...
Source: Asbestos and Mesothelioma News - May 21, 2018 Category: Environmental Health Authors: Matt Mauney Source Type: news

In Lupus, Time on Dialysis Matters
(MedPage Today) -- Survival in lupus nephritis worsens after 24 months of dialysis (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 18, 2018 Category: Primary Care Source Type: news

Obesity Worsens Symptoms in Lupus
(MedPage Today) -- Adiposity associated with pain, fatigue, and depression (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - May 11, 2018 Category: Endocrinology Source Type: news

Cutaneous Lupus Tied to Risk for Coexisting Autoimmune Conditions Cutaneous Lupus Tied to Risk for Coexisting Autoimmune Conditions
Patients with cutaneous lupus erythematosus (CLE) should be monitored closely for other autoimmune conditions, researchers suggest.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 10, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

World Lupus Day: Three women describe living with the disease
May 10 is World Lupus Day. Sue Hayes, 67, describes suffering 10 miscarriages; Amy Baker, 24, was forced to drop out of school; Tracy Hodgson, 42, was left with bubbling skin from her medication. (Source: the Mail online | Health)
Source: the Mail online | Health - May 10, 2018 Category: Consumer Health News Source Type: news

Obesity may worsen symptoms for patients with lupus
(Wiley) In a recent Arthritis Care& Research study of 148 women with lupus, obesity was linked with worse disease activity, depressive symptoms, and symptoms of pain and fatigue. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 10, 2018 Category: International Medicine & Public Health Source Type: news

Renal Outlook Improves in Lupus (CME/CE)
(MedPage Today) -- Increasing incidence of milder clinical syndromes since 1970 (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 9, 2018 Category: Primary Care Source Type: news

May is #LupusAwarenessMonth! Learn about the research being done to help develop therapies for lupus: https://go.usa.gov/xQNCM   pic.twitter.com/BK8UkUtfw2
May is #LupusAwarenessMonth! Learn about the research being done to help develop therapies for lupus: https://go.usa.gov/xQNCM  pic.twitter.com/BK8UkUtfw2 (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - May 8, 2018 Category: Medical Devices Authors: ( at FDAOMH) Source Type: news

C1q restrains autoimmunity and viral infection by regulating CD8+ T cell metabolism
Deficiency of C1q, the initiator of the complement classical pathway, is associated with the development of systemic lupus erythematosus (SLE). Explaining this association in terms of abnormalities in the classical pathway alone remains problematic because C3 deficiency does not predispose to SLE. Here, using a mouse model of SLE, we demonstrate that C1q, but not C3, restrains the response to self-antigens by modulating the mitochondrial metabolism of CD8+ T cells, which can themselves propagate autoimmunity. C1q deficiency also triggers an exuberant effector CD8+ T cell response to chronic viral infection leading to letha...
Source: ScienceNOW - May 3, 2018 Category: Science Authors: Ling, G. S., Crawford, G., Buang, N., Bartok, I., Tian, K., Thielens, N. M., Bally, I., Harker, J. A., Ashton-Rickardt, P. G., Rutschmann, S., Strid, J., Botto, M. Tags: Immunology reports Source Type: news

Gilead inks $90m deal with Verily to create “molecular map” of inflammatory disease
Gilead Sciences (NSDQ:GILD) is reportedly slated to pay Alphabet’s Verily Life Sciences $90 million over three years to analyze cells from patients with rheumatoid arthritis, inflammatory bowel disease and lupus-related diseases. By probing immune cells from patients involved in Gilead’s clinical trials, the companies hope to glean a better understanding of the immunological signatures of RA, IBD and lupus-related diseases. It’s the first large-scale use of Verily’s Immunoscape platform, which combines immunogenomic phenotyping and computational analysis to profile the molecular chara...
Source: Mass Device - May 1, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Diagnostics Drug-Device Combinations Pharmaceuticals Wall Street Beat Gilead Sciences Verily Source Type: news

2 big Bay Area companies look to map, tackle inflammatory diseases
Scientific powerhouses Gilead Sciences Inc. and Verily Life Sciences will work together to find a molecular map of the immune system in lupus, rheumatoid arthritis and inflammatory bowel disease and how it responds to drugs in development. The deal, the value of which wasn't disclosed Monday, comes as the power of understanding and manipulating the immune system to tackle those conditions, cancer and other diseases has taken center stage over the past few years. Gilead (NASDAQ: GILD) will use the… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - April 30, 2018 Category: American Health Authors: Ron Leuty Source Type: news

2 big Bay Area companies look to map, tackle inflammatory diseases
Scientific powerhouses Gilead Sciences Inc. and Verily Life Sciences will work together to find a molecular map of the immune system in lupus, rheumatoid arthritis and inflammatory bowel disease and how it responds to drugs in development. The deal, the value of which wasn't disclosed Monday, comes as the power of understanding and manipulating the immune system to tackle those conditions, cancer and other diseases has taken center stage over the past few years. Gilead (NASDAQ: GILD) will use the… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - April 30, 2018 Category: Biotechnology Authors: Ron Leuty Source Type: news

Subcutaneous Belimumab Improves Systemic Lupus Erythematosus Outcomes Subcutaneous Belimumab Improves Systemic Lupus Erythematosus Outcomes
Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - April 30, 2018 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news

Gilead To Pay Verily $90 Million To Probe Immune Cells
Gilead Sciences will pay up to $90 million over three years to Verily to run a suite of tests on the white blood cells of patients with rheumatoid arthritis, inflammatory bowel disease, and lupus in the hopes of identifying which patients respond to existing drugs. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - April 30, 2018 Category: Pharmaceuticals Authors: Matthew Herper, Forbes Staff Tags: NASDAQ:GILD NASDAQ:GOOG Source Type: news

What Causes Flushing?
Discussion Flushing is usually thought of as a benign condition such as blushing, but can be quite irritating if it is frequent or persistent (i.e. menopausal hot flashes) or even pathologic (i.e. malignancy). “Flushing is a subjective and sensation of warmth that is accompanied by reddening of the skin anywhere on the body but favors the face, neck, and upper torso…. Flushing can be broadly divided into episodic or persistent. Episodic flashing is mediated by the release of endogenous vasoactive mediators or medications, while persistent flushing result in a fixed facial erythema with telangiectasias and cyan...
Source: PediatricEducation.org - April 30, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Lupus Is a Leading Cause of Death in Young Women
WEDNESDAY, April 25, 2018 -- Systemic lupus erythematous (SLE) is among the top 20 leading causes of death in females between the ages of 5 and 64 years in the United States, according to a study published online April 18 in Arthritis&... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 25, 2018 Category: Pharmaceuticals Source Type: news

Medical News Today: What is a malar rash?
A malar rash is also known as a butterfly rash and appears on the face. It is usually red or purple and may be blotchy or solid. It can occur alongside many conditions, including lupus and rosacea. Treatment depends on the cause. There are lifestyle tips and tricks that can help. Learn more about the best ones here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 24, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Epstein-Barr virus and autoimmune diseases
Researchers found a mechanism that may explain why the Epstein-Barr virus is associated with certain autoimmune illnesses such as lupus. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - April 24, 2018 Category: Consumer Health News Source Type: news

Belimumab Aids Anti-dsDNA & #43;, Hypocomplementemic Lupus
MONDAY, April 23, 2018 -- Weekly belimumab is associated with greater benefit than placebo for patients with hypocomplementemic/anti-double stranded (ds)DNA-positive systemic lupus erythematosus (SLE), according to a study published online April 18... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 23, 2018 Category: Pharmaceuticals Source Type: news

Injectible drug shown to be effective against lupus in clinical trial
Injections of the drug Belimumab, marketed as Benlysta, benefited patients with a form of lupus in a Phase 3 clinical trial, researchers reported this week. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 20, 2018 Category: Consumer Health News Source Type: news

Lupus Subgroup Responds to Anti-CD22 (CME/CE)
(MedPage Today) -- Patients with concomitant Sjogren's syndrome improved with epratuzumab (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 20, 2018 Category: Primary Care Source Type: news

Colleague's Consult in Rheumatology
(MedPage Today) -- Exclusive video with Susan Manzi, MD, Co-Director of the Lupus Center of Excellence at Allegheny Health Network and Jill Buyon, MD, Director of the Division of Rheumatology at NYU Langone Health. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - April 20, 2018 Category: Rheumatology Source Type: news

Lupus treatment generates positive results in Phase III clinical trial
(Wiley) New research indicates that belimumab, a monoclonal antibody therapy that targets a component of the immune system, provides considerable benefits to patients with systemic lupus erythematosus (SLE), a predominately female, chronic inflammatory disease that can affect virtually any organ. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 20, 2018 Category: International Medicine & Public Health Source Type: news

Compound treats psoriasis, may curb autoimmune diseases, researchers say
A compound from immune cells treats psoriasis in mice and might also be effective in treating multiple sclerosis, rheumatoid arthritis and lupus. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 18, 2018 Category: Consumer Health News Source Type: news

With Antimalarials in Lupus, Watch for Retinal Toxicity
(MedPage Today) -- Following guidelines will minimize risk, specialist says (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - April 17, 2018 Category: Rheumatology Source Type: news

Epstein-Barr virus protein can “switch on” risk genes for autoimmune diseases
EBV may trigger some cases of lupus, say NIH-supported researchers. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 16, 2018 Category: American Health Source Type: news

Epstein-Barr virus protein can 'switch on' risk genes for autoimmune diseases
(NIH/National Institute of Allergy and Infectious Diseases) Infection with Epstein-Barr virus (EBV), the cause of infectious mononucleosis, has been associated with subsequent development of systemic lupus erythematosus and other chronic autoimmune illnesses, but the mechanisms behind this association were unclear. Now, a novel computational method shows that a viral protein found in EBV-infected human cells may activate genes associated with increased risk for autoimmunity. Scientists supported by the National Institute of Allergy and Infectious Diseases report their findings today in Nature Genetics. (Source: EurekAlert!...
Source: EurekAlert! - Infectious and Emerging Diseases - April 16, 2018 Category: Infectious Diseases Source Type: news

You Asked: What Is Inflammation, And Why Should I Care About It?
Your body can heal itself, which is pretty miraculous when you sit back and think about it. If you suffer a cut or infection—or if a disease, allergen or virus finds its way into you—your immune system reacts by sending specialized white blood cells to the affected area. These white blood cells can repair damage, stop the spread of infection or illness and in some cases eradicate the intruder. This whole response is called inflammation. “Inflammation is an activation of cells and cell-derived components that have the job of fighting invasions, and in some cases just sponging up or clearing out damaged cel...
Source: TIME: Health - April 11, 2018 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthytime medicine Source Type: news

The BSR Guideline for the Management of SLE in Adults The BSR Guideline for the Management of SLE in Adults
A new guideline from the British Society for Rheumatology offers guidance for the management of systemic lupus erythematosus in adults.Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 11, 2018 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Metabolic Syndrome Common in Patients With Lupus
TUESDAY, April 10, 2018 -- As with the general population, metabolic syndrome (MetS) is common among patients with systemic lupus erythematosus (SLE), according to a study published online April 3 in the International Journal of Rheumatic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 10, 2018 Category: Pharmaceuticals Source Type: news

Study points to potential personalized approach to treating lupus
A new finding by Yale researchers opens the door to future Lupus therapies targeting bacteria rather than the patient ’s immune system. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 28, 2018 Category: Universities & Medical Training Source Type: news

Predictive Biomarkers of Systemic Lupus Erythematosus Flares Predictive Biomarkers of Systemic Lupus Erythematosus Flares
Which biomarkers may predict the occurrence of new SLE flares?Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2018 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Identification and Management of Lupus Nephritis Identification and Management of Lupus Nephritis
Find out what there is to know regarding the diagnosis and medical management of lupus nephritis.Journal for Nurse Practitioners (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 12, 2018 Category: Consumer Health News Tags: Nursing Journal Article Source Type: news

Medical News Today: Could targeting gut bacteria prevent autoimmunity?
A gut bacterium called Enterococcus gallinarum can drive autoimmune diseases such as lupus, new research finds. Could targeting it offer a new treatment? (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 9, 2018 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

A Role for Rituximab in Lupus?
(MedPage Today) -- Half of refractory patients responded in 6 months (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - March 8, 2018 Category: Rheumatology Source Type: news

Cancer patients shed new light on rheumatoid arthritis
Side-effects in immunotherapy for cancer patients have given scientists an ally in the battle against rheumatoid arthritisThe human immune system is one of the most effective defence mechanisms known to nature. It can ward off myriad microbial invaders: bacteria, viruses and parasites. It is sometimes overwhelmed by disease, of course, but the billions of men and women who now live on Earth are a testament – at least in part – to the effectiveness of their immune defences.However, on occasions they go too far. Instead of killing off invading organisms, our immune systems turn on our own tissue and attack it. Co...
Source: Guardian Unlimited Science - March 3, 2018 Category: Science Authors: Robin McKie Tags: Immunology Science Cancer research Biology Source Type: news