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Poverty Affects Severity of Organ Damage Due to Lupus
And, pregnancy complications higher among non - white patients with lupus (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - May 23, 2017 Category: Respiratory Medicine Tags: Cardiology, Family Medicine, Gynecology, Internal Medicine, Nephrology, Neurology, Nursing, Pathology, Pulmonology, Rheumatology, Journal, Source Type: news

Joint pain could be a symptom of THIS potentially life-threatening condition
LUPUS is a complex disease which affects individuals in many different ways and with differing severity. Joint pain is one of the main symptoms of the condition. (Source: Daily Express - Health)
Source: Daily Express - Health - May 21, 2017 Category: Consumer Health News Source Type: news

Poverty Could Make Lupus Even Worse
Second study saw pregnancy complications higher among non-whites Source: HealthDay Related MedlinePlus Pages: Health Disparities, Health Problems in Pregnancy, Lupus (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 19, 2017 Category: Consumer Health News Source Type: news

Poverty Could Make Lupus Even Worse
FRIDAY, May 19, 2017 -- Poverty and race are tied to the health of lupus patients in the United States, according to two new studies. One study of 783 patients linked poverty to an increased risk of organ damage from the autoimmune disease. It was... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 19, 2017 Category: General Medicine Source Type: news

Living with lupus: what it's like having an invisible illness
Lisa Walters is a 28-year-old living with lupus, or what she refers to as an invisible illness. (Source: CBC | Health)
Source: CBC | Health - May 19, 2017 Category: Consumer Health News Tags: News/Canada/NL Source Type: news

Aurinia begins voclosporin dosing in Phase III trial for LN
Canadian-based biopharmaceutical firm Aurinia Pharmaceuticals has begun dosing patients in the Phase III AURORA clinical trial of voclosporin to treat lupus nephritis (LN). (Source: Drug Development Technology)
Source: Drug Development Technology - May 18, 2017 Category: Pharmaceuticals Source Type: news

Systemic Lupus Erythematosus: Osmosis Study Video Systemic Lupus Erythematosus: Osmosis Study Video
This video covers the known pathophysiology behind systemic lupus erythematosus, as well as the diagnostic criteria, signs and symptoms, and treatment. (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 16, 2017 Category: Consumer Health News Tags: Med Students Commentary Source Type: news

Erratum for the Research Article: "Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus" by I. A. Buskiewicz, T. Montgomery, E. C. Yasewicz, S. A. Huber, M. P. Murphy, R. C. Hartley, R. Kelly, M. K. Crow, A. Perl, R. C. Budd, A. Koenig
(Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - May 16, 2017 Category: Science Tags: STKE Errata Source Type: news

New report reveals 1 in 4 children in UK lives in poverty
Poverty is ‘making children sick,’ say paediatricians Related items fromOnMedica NHS bears brunt of cost of poverty Studies reveal socioeconomic and race disparities in lupus Preschool tooth extractions rise by a quarter Child type 2 diabetes is a ‘wake-up call’ to the nation Eight-year-olds to get 'happiness lessons' (Source: OnMedica Latest News)
Source: OnMedica Latest News - May 12, 2017 Category: UK Health Source Type: news

Researchers identify trigger for autoimmune disease
Researchers at National Jewish Health have identified age-associated B cells are a trigger for autoimmune diseases like lupus and Crohn's disease. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 11, 2017 Category: Consumer Health News Source Type: news

Boehringer begins enrolment in Phase II trial of BI 655064 to treat lupus nephritis
Pharmaceutical company Boehringer Ingelheim has begun patient enrolment in the Phase II clinical trial of BI 655064 for the treatment of lupus nephritis (LN). (Source: Drug Development Technology)
Source: Drug Development Technology - May 10, 2017 Category: Pharmaceuticals Source Type: news

Trigger for autoimmune disease identified
Researchers have identified a trigger for autoimmune diseases such as lupus, Crohn's disease and multiple sclerosis. The findings help explain why women suffer autoimmune disease more frequently than men, and suggest a therapeutic target to prevent autoimmune disease in humans. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 10, 2017 Category: Science Source Type: news

Phase II Trial now enrolling patients with Lupus Nephritis
(Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - May 10, 2017 Category: Research Source Type: news

Trigger for autoimmune disease identified
(National Jewish Health) Researchers at National Jewish Health have identified a trigger for autoimmune diseases such as lupus, Crohn's disease and multiple sclerosis. The findings help explain why women suffer autoimmune disease more frequently than men, and suggest a therapeutic target to prevent autoimmune disease in humans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 10, 2017 Category: International Medicine & Public Health Source Type: news

Enteric-coated Mycophenolate Sodium May Trump Azathioprine for SLE Enteric-coated Mycophenolate Sodium May Trump Azathioprine for SLE
Enteric-coated mycophenolate sodium (EC-MPS) may treat systemic lupus erythematosus (SLE) more effectively than azathioprine (AZA) and prevent further relapses, researchers in Spain suggest.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - May 9, 2017 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news

Studies reveal socioeconomic and race disparities in lupus
Poverty linked with medical complications over time Related items fromOnMedica Arthritis may be a major driver of poverty NHS bears brunt of cost of poverty Rich and poor lifespan gap widens Blood test identifies high-risk lupus pregnancies (Source: OnMedica Latest News)
Source: OnMedica Latest News - May 9, 2017 Category: UK Health Source Type: news

Studies show socioeconomic and racial disparities in lupus
Researchers have identified a link between socioeconomic and racial disparities in the severity and treatment of lupus. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 8, 2017 Category: Consumer Health News Source Type: news

Better Lupus Remission with Mycophenolate (CME/CE)
(MedPage Today) -- Complete SLE remission sooner, more frequent than with azathioprine (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - May 5, 2017 Category: Consumer Health News Source Type: news

Renal Data Reassuring in Lupus Pregnancy (CME/CE)
(MedPage Today) -- De novo nephritis numbers were miniscule in prospective study (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - May 4, 2017 Category: OBGYN Source Type: news

GlaxoSmithKline announces $139 million investment in Rockville
British drug giant GlaxoSmithKline PLC (NYSE: GSK) is investing $139 million to expand its Rockville manufacturing site, saying it needs extra capacity there to meet anticipated demand for its lupus drug. Already, the Rockville location manufactures a drug substance in bulk for Benlysta as an intravenous formulation. That substance is also used to make GSK's asthma drug Nucala and its drug for inhaled anthrax called raxibacumab. But now, GSK is hoping to boost that bulk production by about 50 perce nt. The… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - May 1, 2017 Category: Pharmaceuticals Authors: Tina Reed Source Type: news

GlaxoSmithKline making $139M investment in Rockville plant
British drug giant GlaxoSmithKline PLC (NYSE: GSK) is investing $139 million to expand its Rockville manufacturing site, saying it needs extra capacity there to meet anticipated demand for its lupus drug. The expansion would allow the company to boost bulk production of a substance used in several of its drugs, including Benlysta, by about 50 percent. The expansion comes as the pharmaceutical giant is awaiting Food and Drug Administration approval to sell a new self-injectable form of Benlysta.… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - May 1, 2017 Category: Health Management Authors: Tina Reed Source Type: news

Lupus Patients at Risk for Stroke (CME/CE)
(MedPage Today) -- Risks high for women, the young, and during the year after diagnosis (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 23, 2017 Category: Primary Care Source Type: news

Mid-Stage Voclosporin Data Look Good in Lupus Nephritis (CME/CE)
(MedPage Today) -- 48-week findings of AURA-LV reported high rates of complete, partial remission (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 21, 2017 Category: Primary Care Source Type: news

A Rosy Outlook for Pregnancy and Lupus A Rosy Outlook for Pregnancy and Lupus
One doctor's research is helping reassure pregnant women with lupus that in most cases, their pregnancies should be free of complications.Hospital for Special Surgery (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - April 20, 2017 Category: Allergy & Immunology Tags: Rheumatology Expert Interview Source Type: news

Ultrasensitive detection of protein linked to multiple autoimmune diseases
Researchers have developed a new method that will allow doctors to detect minute amounts of a protein called interferon- in patient samples. The technique will aid the diagnosis and treatment of numerous autoimmune diseases, including systemic lupus erythematosus (SLE) and dermatomyositis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 18, 2017 Category: Science Source Type: news

Researchers describe ultrasensitive detection of protein linked to multiple autoimmune diseases
(Rockefeller University Press) Researchers in France have developed a new method that will allow doctors to detect minute amounts of a protein called interferon- in patient samples. The technique, which is described in the study 'Detection of interferon- protein reveals differential levels and cellular sources in disease' published April 18 in The Journal of Experimental Medicine, will aid the diagnosis and treatment of numerous autoimmune diseases, including systemic lupus erythematosus (SLE) and dermatomyositis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 18, 2017 Category: Global & Universal Source Type: news

Xencor Appoints Kevin Gorman, Ph.D., to its Board of Directors
MONROVIA, Calif., April 17, 2017 -- (Healthcare Sales & Marketing Network) -- Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of inflammation and cancer, today announced... Biopharmaceuticals, Personnel Xencor, XmAb, Systemic Lupus Erythematosus, acute myeloid leukemia (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 17, 2017 Category: Pharmaceuticals Source Type: news

Kids Face Slightly Higher Allergy Risk When Mom Has Lupus (CME/CE)
(MedPage Today) -- Odds ratio of 1.35; less risk than for certain other adverse outcomes (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - April 16, 2017 Category: Allergy & Immunology Source Type: news

Remission in SLE: Durable Remission Is Rare Remission in SLE: Durable Remission Is Rare
An examination of the remission rates in systemic lupus erythematosus provides insight into the frequency and duration of remission in this inflammatory disease.Annals of the Rheumatic Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 14, 2017 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Multiple Metabolic Abnormalities Seen in Lupus (CME/CE)
(MedPage Today) -- Targeting insulin resistance alone won't be enough (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - April 4, 2017 Category: Endocrinology Source Type: news

The Value of an Early Diagnosis of Lupus to Improve Health Outcomes Among Hispanics
March 31, 2017 1-2pm ET.(Lupus Foundation of America) (Source: HSR Information Central)
Source: HSR Information Central - March 30, 2017 Category: Global & Universal Source Type: news

Lupus Research Alliance Novel Research Grants push discoveries
(Lupus Research Institute) The Lupus Research Alliance announced today the Novel Research Grant Class of 2017. The Lupus Research Alliance Novel Research Grants, the proven platform for innovation, make discovery and scientific progress possible. This year's grantees push science out in front and ahead of the curve to deliver 10 innovative approaches seeking results that can transform the lives of people with lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 30, 2017 Category: Global & Universal Source Type: news

Lupus: What you need to know
An invisible disease with debilitating symptoms, lupus is more common than you might think. Learn about the causes, triggers and treatments for this devastating disease. (Source: CNN.com - Health)
Source: CNN.com - Health - March 28, 2017 Category: Consumer Health News Source Type: news

Does Stress Affect Lupus
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - March 27, 2017 Category: Journals (General) Source Type: news

The next generation of prenatal testing: let ’s proceed with caution
Catherine Joynson, from the Nuffield Council on Bioethics, discusses a new prenatal screening test launching in 2018 Related items fromOnMedica Leading the way with NHS Screening Programmes Blood test identifies high-risk lupus pregnancies Maternity care to become more ‘personalised’ New NHS screening for Down's expected soon (Source: OnMedica Views)
Source: OnMedica Views - March 20, 2017 Category: Primary Care Source Type: news

Belimumab for Lupus: Helpful in the Real World (CME/CE)
(MedPage Today) -- More than half had improvement of 50% or more at 6 months (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 18, 2017 Category: Primary Care Source Type: news

Facial erythema: Side effects of anti-fungal drugs - drug rashes
View the full imagePatient AB: Voriconazole rash. Following 8 weeks of Voriconazole, patient had remarkable facial erythema, most consistent with sun exposure because of sparing of her neck.View the full imagePatient AB: Voriconazole rash. Following 8 weeks of Voriconazole, patient had remarkable facial erythema, most consistent with sun exposure because of sparing of her neck.View the full imagePatient AB: Discoid lupus erythematosus following 12 months voriconazole therapy. This improved with use of sunblock factor 30 and resolved after discontinuation of voriconazole, 2 months later.Facial erythema: Side effects of anti...
Source: The Aspergillus Website - updates - March 17, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Modified red blood cells 'could alleviate autoimmune diseases'
This study is interesting and has the potential to be a tool used to both treat and prevent rheumatoid arthritis. It is promising to see that autoimmunity could be treated in mice, but people with arthritis need to be aware that this research is in its very early stages. "More research is needed to determine how the results can be translated into a benefit for people living inpain now, and for those who may develop arthritis in the future." (Source: Arthritis Research UK)
Source: Arthritis Research UK - March 17, 2017 Category: Rheumatology Source Type: news

Selena Gomez Says Therapy Completely Changed Her Life
Can we get an amen for this? Selena Gomez spoke to Vogue about recently taking a break from the spotlight to focus on her psychological well-being. She candidly praised the power of therapy in the interview, saying she sees a mental health professional five days a week. Gomez, who revealed in 2015 she had been diagnosed with lupus, specifically credited Dialectical Behavioral Therapy for helping her manage depression and anxiety. The technique, a form of talk therapy, teaches patients how to “accept” uncomfortable thoughts in order to make it easier to change them. The practice also places an emp...
Source: Healthy Living - The Huffington Post - March 16, 2017 Category: Consumer Health News Source Type: news

Tackling Lupus and its renal complications with novel small molecule drug candidate
A drug starting through the pipeline could ameliorate or even eliminate the symptoms in most lupus sufferers, report researchers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 7, 2017 Category: Science Source Type: news

Infection Rates High in Kids with SLE (CME/CE)
(MedPage Today) -- Highest rates seen in those with lupus nephritis (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 23, 2017 Category: Infectious Diseases Source Type: news

Neanderthal DNA contributes to human gene expression
The last Neanderthal died 40,000 years ago, but much of their genome lives on, in bits and pieces, through modern humans. The impact of Neanderthals'genetic contribution has been uncertain. Researchers now report evidence that Neanderthal DNA sequences still influence how genes are turned on or off in modern humans. Neanderthal genes'effects on gene expression likely contribute to traits such as height and susceptibility to schizophrenia or lupus, the researchers found. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 23, 2017 Category: Science Source Type: news

Neovacs and BioSense partner to develop and commercialise IFNa Kinoid in China
French-based Neovacs has signed a commercial licence option agreement with BioSense Global for the development and commercial rights of IFN α Kinoid vaccine to treat lupus and dermatomyositis in China. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - February 22, 2017 Category: Pharmaceuticals Source Type: news

Infections in Lupus: Do Meds Contribute? (CME/CE)
(MedPage Today) -- Steroids and immunosuppressants risky; antimalarials benefit (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 14, 2017 Category: Infectious Diseases Source Type: news

Systemic Lupus Erythematosus Quiz: Test Your SLE IQ
Title: Systemic Lupus Erythematosus Quiz: Test Your SLE IQCategory: MedicineNet QuizCreated: 8/17/2011 1:33:00 PMLast Editorial Review: 2/13/2017 3:45:54 PM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 13, 2017 Category: Rheumatology Source Type: news

Stressed out interferons reveal potential key to alternative lupus treatment
New research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target for treating the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 10, 2017 Category: Science Source Type: news

Stressed out interferons reveal potential key to alternative lupus treatment
(University of Vermont) New research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target for treating the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 10, 2017 Category: Global & Universal Source Type: news

Study of complex genetic region finds hidden role of NCF1 in multiple autoimmune diseases
(Medical University of South Carolina) Medical University of South Carolina investigators report pre-clinical research showing that a genetic variant encoded in neutrophil cystolic factor 1 (NCF1) is associated with increased risk for autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sj ö gren's syndrome, in the January 2017 issue of Nature Genetics. Data indicate that increased NCF1 protects against SLE while decreased NCF1 raises SLE risk and highlight the pathogenic role of reduced reactive oxygen species in autoimmune disease development. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 8, 2017 Category: Biology Source Type: news

Lupus in Kids: Damage Starts Early (CME/CE)
(MedPage Today) -- Antimalarials helped protect against organ damage (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - February 5, 2017 Category: Pediatrics Source Type: news

Lupus: A Continuum of Disease? (CME/CE)
(MedPage Today) -- Incomplete lupus is often mild, but can progress, cause damage (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 31, 2017 Category: Primary Care Source Type: news