AI-Enabled Stethoscope Brings Specialized Knowledge to the Point of Care
Recent results of a collaborative study between Eko and the Mayo Clinic demonstrating the use of Eko’s DUO digital stethoscope as a heart failure screening tool suggest that the device could help identify asymptomatic patients with low ejection fraction during routine physical examinations. “The low ejection fraction algorithm was used with a very specific protocol of four touchpoints—three on the chest and one on the fingers,” said Steve Pham, MD, vice president of clinical and research affairs at Eko, in an interview with MD+DI. â&#...
Source: MDDI - December 11, 2019 Category: Medical Devices Authors: Susan Shepard Tags: Digital Health Source Type: news

Racial Differences Seen With Hypertrophic Cardiomyopathy
THURSDAY, Dec. 5, 2019 -- Racial differences in disease expression and adverse clinical outcomes exist between black and white patients with hypertrophic cardiomyopathy, according to a study published online Dec. 4 in JAMA Cardiology. Lauren A.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 5, 2019 Category: Pharmaceuticals Source Type: news

World's most comprehensive study of a deadly heart condition yields 1st results
(University of Virginia Health System) Researchers have revealed the initial results from the world's largest comprehensive study of hypertrophic cardiomyopathy, an abnormal thickening of the heart that often goes undiagnosed and can prove deadly. The condition can present at any age, and it is the most common cause of sudden cardiac death in young athletes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 7, 2019 Category: International Medicine & Public Health Source Type: news

Ultra-Low SCD Risk Seen in HCM Challenges Prevailing Views Ultra-Low SCD Risk Seen in HCM Challenges Prevailing Views
The risk is'an order of magnitude lower'and exercise less often a trigger in hypertrophic cardiomyopathy than often thought in current practice, with implications for ICDs.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 2, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Nov 1 2019 This Week in Cardiology Nov 1 2019 This Week in Cardiology
Mortality after AF ablation, cardiac rehab programs, hypertrophic cardiomyopathy, and clinician wellness are the topics Dr. John Mandrola discusses in this week ’ s podcast.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 1, 2019 Category: Cardiology Tags: Cardiology Commentary Source Type: news

AHA News: Deadly Heart Problem Might Not Be So Deadly
MONDAY, Oct. 21, 2019 (American Heart Association News) -- An incurable condition called hypertrophic cardiomyopathy may be less deadly than previously thought, according to a new study of sudden cardiac deaths among young people. At least 1 in 500... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 21, 2019 Category: General Medicine Source Type: news

New Algorithm Can Help Predict Sudden-Death Risk in Kids With Hypertrophic Cardiomyopathy New Algorithm Can Help Predict Sudden-Death Risk in Kids With Hypertrophic Cardiomyopathy
Researchers have developed a new model to predict the individualized risk of sudden cardiac death (SCD) in children with hypertrophic cardiomyopathy.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - August 27, 2019 Category: Radiology Tags: Cardiology News Source Type: news

Heart cells ’ environment a potentially major factor in heart disease
New research shows the role that a diseased extracellular matrix plays in the progression of the genetic condition hypertrophic cardiomyopathy. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 24, 2019 Category: Universities & Medical Training Source Type: news

Hypertrophic Cardiomyopathy, Diabetes, and the Test of Time Hypertrophic Cardiomyopathy, Diabetes, and the Test of Time
How does diabetes mellitus impact the clinical profile and outcome of patients with hypertrophic cardiomyopathy? How might it affect disease management?European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 15, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Guidelines for HOCM Treatment: A Moving Target? Guidelines for HOCM Treatment: A Moving Target?
The optimal treatment for symptomatic hypertrophic obstructive cardiomyopathy continues to be a subject of debate among surgeons and cardiologists.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 10, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Published Study Supports MyoKardia ’s Wrist-Worn Biosensor
MyoKardia’s said data on its wrist-worn digital health device was published in an article titled, “Machine Learning Detection of Obstructive Hypertrophic Cardiomyopathy (oHCM) Using a Wearable Biosensor,” in the Nature Partner Journal, Digital Medicine. The South San Francisco-based company said results from an exploratory study provided encouraging evidence of the potential for a wrist-worn biosensor to screen for obstructive hypertrophic cardiomyopathy. The study demonstrated that continuous monitoring using a wrist-worn photoplethysmography (PPG) digital health devic...
Source: MDDI - June 24, 2019 Category: Medical Devices Authors: MDDI Staff Tags: Business Cardiovascular Source Type: news

New Technology Saves Those With Genetic Heart Disease
BOSTON (CBS) – We’ve all heard the tragic tales of teens and young adults collapsing while playing sports from a rare heart condition. Now, a father-son team in Boston has developed a strategy to save those patients most at risk. “It was devastating.”  Kevin Whelan recalled the moment he learned his oldest brother, Kyle, collapsed and died. He was only 26 years old. Kyle had hypertrophic cardiomyopathy, or HCM, a genetic disease of the heart and the most common cause of sudden death in otherwise healthy young people. But Kyle wasn’t the only one in the family with it.  His father and...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Hypertrophic Cardiomyopathy Source Type: news

New Strategy Saving Those With Genetic Heart Disease
BOSTON (CBS) – We’ve all heard the tragic tales of teens and young adults collapsing while playing sports from a rare heart condition. Now, a father-son team in Boston has developed a strategy to save those patients most at risk. “It was devastating.”  Kevin Whelan recalled the moment he learned his oldest brother, Kyle, collapsed and died. He was only 26 years old. Kyle had hypertrophic cardiomyopathy, or HCM, a genetic disease of the heart and the most common cause of sudden death in otherwise healthy young people. But Kyle wasn’t the only one in the family with it.  His father and...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Hypertrophic Cardiomyopathy Source Type: news

Heart scan 'could pick up signs of sudden death risk'
Researchers used detailed images of the heart to look for signs of hypertrophic cardiomyopathy. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 20, 2019 Category: Consumer Health News Source Type: news

Breakthrough as scientists can now spot leading cause of cardiac arrest in young people
Oxford University scientists have found a way to use MRI scanners to picture the arrangement of muscle fibres in the heart to pick out warning signs of hypertrophic cardiomyopathy. (Source: the Mail online | Health)
Source: the Mail online | Health - May 20, 2019 Category: Consumer Health News Source Type: news

The ECG and the Phenotypic Expression of HCM The ECG and the Phenotypic Expression of HCM
What is the significance of marked ECG abnormalities in an individual with a positive genotype for hypertrophic cardiomyopathy?European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 8, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Continuous ECG Changes Over 8 Years in an Athlete With HCM Continuous ECG Changes Over 8 Years in an Athlete With HCM
This case report reveals that abnormal ECG findings may precede the symptoms and signs of hypertrophic cardiomyopathy for many years.Journal of Medical Case Reports (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - May 8, 2019 Category: Radiology Tags: Cardiology Journal Article Source Type: news

A promising new treatment for infants with Noonan syndrome
(University of Montreal) Infants less than six months old with Noonan Syndrome, hypertrophic cardiomyopathy and congestive heart failure normally have a poor prognosis, with a one-year survival rate of 34%. In the new study, doctors used Trametinib to try to treat NS in two patients.They observed dramatic improvement of clinical and cardiac status in the patients only three months after treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 30, 2019 Category: International Medicine & Public Health Source Type: news

What Is the Most Common Type of Cardiomyopathy?
Discussion Barth syndrome is characterized by a dilated cardiomyopathy, proximal skeletal muscle weakness, neutropenia and short stature that usually presents at birth or soon after. It is a rare X-linked recessive disease process caused by mutations in the TAZ gene. The TAZ gene codes for tafazzin which alters cardiolipin in mitochondria. Characteristic facies can be seen especially in infancy including a tall and broad forehead, prominent chin and full cheeks, larger ears, and deep-set eyes. Most patients present at birth or soon afterwards but some may not until later in life. Life expectancy is reduced with many childr...
Source: PediatricEducation.org - February 25, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Scientists unravel genetic basis of hypertrophic cardiomyopathy in Finns
(University of Eastern Finland) One third of hypertrophic cardiomyopathy cases in Finland are caused by one of the four major mutations, a new study from the University of Eastern Finland and Kuopio University Hospital shows. Overall, 40 percent of patients carried a specific or a likely mutation causing the disease, and 20 percent were carriers of a rare gene mutation whose role in the disease remains unknown. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 22, 2019 Category: International Medicine & Public Health Source Type: news

Bad brakes
(Harvard Medical School) A study in human and mouse heart cells identifies a faulty molecular brake in the most common form of hypertrophic cardiomyopathy, a leading cause of sudden cardiac death in young people and athletes and the most common genetic disease of the heart The faulty brake, found about a quarter of all genetic mutations in hypertrophic cardiomyopathy, interferes with the heart muscle's ability to contract and relax,.Treatment with a chemical compound successfully restores normal contractility and relaxation in human heart cells (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 28, 2019 Category: International Medicine & Public Health Source Type: news

Hypertrophic Cardiomyopathy: A to Z with Richard Bach, MD
(MedPage Today) -- Andrew Perry, MD, interviews specialty center director (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - December 28, 2018 Category: Urology & Nephrology Source Type: news

Weekly Postings
See something of interest? Please share our postings with colleagues in your institutions! Spotlight The MAReport: read the Summer/Fall 2018 issue of the MAReport newsletter! Have you had the chance to meet our Health Programming Coordinator? Learn more about the newest member of the MAR team, Michael Balkenhol! DOCLINE users! Please review the DOCLINE 6.0 Preview Checklist. Questions or concerns? Contact the DOCLINE Coordinating Office (NDCO) via email: DOCLINE@hshsl.umaryland.edu or telephone: (410) 706-4173. National Network of Libraries of Medicine News NNLM All of Us Community Engagement Awards: NNLM MAR is accep...
Source: NN/LM Middle Atlantic Region Blog - November 9, 2018 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Weekly Postings Source Type: news

GOOD WORKS SA: Losing son inspires creation of AugustHeart
Ten years after Bart Koontz's teenage son died, his voice wavers with emotion as he recounts the morning August never woke due to an undetected heart condition called hypertrophic cardiomyopathy. A few years later, in 2011, Bart and Dore Koontz founded AugustHeart with a bold vision: to establish and fund a rapid, low-cost, scalable cardiovascular screening model. Their goal was a free communitywide cardiac screening program for all teens in Bexar County to minimize the risks of sudden car diac arrest,… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 26, 2018 Category: American Health Authors: Andi Rodriguez Source Type: news

Researchers determine how contraction leads to hypertrophic cardiomyopathy
Individual myosin molecules and rod-like filaments inside muscles produce less force and lower velocity of contraction, leading to hypertrophic cardiomyopathy, researcher report in a new study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 16, 2018 Category: Consumer Health News Source Type: news

Why heart contractions are weaker in those with hypertrophic cardiomyopathy
(McGill University) Familial hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease in the US and affects an estimated 1 in 500 people around the world. A protein called myosin acts as the molecular motor which makes the muscles in the heart contract. An international team has discovered that in transgenic rabbits with the R403Q mutation,, individual myosin molecules and myofibrils (the basic rod-like filaments inside muscles) produce less force and a lower maximum velocity of contraction than those isolated from healthy hearts. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 16, 2018 Category: International Medicine & Public Health Source Type: news

The man who has died NINE times: 29-year-old's illness regularly makes his heart stop
Jamie Poole, from Australia but living in London, has hypertrophic cardiomyopathy, which means his heart muscle is thickened and weaker, and causes him regular cardiac arrests. (Source: the Mail online | Health)
Source: the Mail online | Health - October 4, 2018 Category: Consumer Health News Source Type: news

Can a common heart condition cause sudden death?
(Gladstone Institutes) About one person out of 500 has a heart condition known as hypertrophic cardiomyopathy (HCM). This condition causes thickening of the heart muscle and results in defects in the heart's electrical system. Under conditions of environmental stress such as exercise, HCM can result in sudden death. In other cases, patients may go undiagnosed, with their heart function declining gradually over decades. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 20, 2018 Category: Biology Source Type: news

CHOP researchers highlight advances in pediatric heart disease at 2017 AHA scientific sessions
(Children's Hospital of Philadelphia) Physician-researchers from the Cardiac Center at Children's Hospital of Philadelphia (CHOP) recently presented new findings on pediatric cardiovascular disease at the American Heart Association's Scientific Sessions 2017 in Anaheim, Calif. Among many abstracts presented were research on racial disparities in bystander CPR methods in children with sudden cardiac arrest, and findings that children with hypertrophic cardiomyopathy may be at risk for sudden cardiac death. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 28, 2017 Category: International Medicine & Public Health Source Type: news

When Heart Disease Runs in the Family
Treatment TermsCardiomyopathy Overview Anne Goodes knew her heart beat faster than normal, but it wasn ’t until her local cardiologist detected a heart murmur that she discovered she was at risk for sudden cardiac death. At Duke, she learned the cause was hypertrophic cardiomyopathy, a common heart condition that can run in the family. Goodes soon discovered her children may need to take precaution s as well. Hero Image2017_anne_heart_596.jpg Preview Image Content Blocks Header Learning to Live with Hypertrophic Cardiomyopathy ContentHypertrophic cardiomyopathy affects the cells that make up the heart muscle,...
Source: dukehealth.org: Duke Health News - November 27, 2017 Category: Consumer Health News Authors: dg62 at duke.edu Source Type: news

MRI discovers heart damage among male triathletes
Using late gadolinium-enhanced MRI scans, German researchers found myocardial...Read more on AuntMinnie.comRelated Reading: Some cardiac MRI findings predict future heart events Stress cardiac MR matches 320-row CCTA results Study shows feasibility of cardiac PET/MRI -- with caveats Cardiac MR tops ECG in finding hidden myocardial infarctions Late MRI enhancement predicts death risk in hypertrophic cardiomyopathy (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 21, 2017 Category: Radiology Source Type: news

Fruit fly muscles with a hypertrophic cardiomyopathy mutation don't relax properly
(Johns Hopkins Medicine) Using fruit flies, Johns Hopkins researchers have figured out why a particular inherited human heart condition that is almost always due to genetic mutations causes the heart to enlarge, thicken and fail. They found that one such mutation interferes with heart muscle's ability to relax after contracting, and prevents the heart from fully filling with blood and pumping it out. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 9, 2017 Category: International Medicine & Public Health Source Type: news

Preventing sudden death in hypertrophic cardiomyopathy: ESC guidelines (HCM-EVIDENCE)
(European Society of Cardiology) A large study conducted across North America, Europe, the Middle East and Asia has validated the ESC recommendations for predicting and preventing sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 29, 2017 Category: International Medicine & Public Health Source Type: news

MyoKardia ’s Phase II trial for oHCM drug meets endpoints
MyoKardia has reported positive top-line results from the first cohort of its Phase II PIONEER-HCM clinical trial of mavacamten in patients with symptomatic, obstructive hypertrophic cardiomyopathy (oHCM). (Source: Drug Development Technology)
Source: Drug Development Technology - August 8, 2017 Category: Pharmaceuticals Source Type: news

Researchers successfully edit 1st human embryo with CRISPR
Scientists have successfully edited genes in a human embryo, correcting a disease-causing mutation to prevent the defect from being inherited. The groundbreaking process, covered in a paper published yesterday in Nature, was confirmed last week by the Oregon Health and Science University, which collaborated with the Salk Institute and Korea’s Institute for Basic Science on the task. To edit the genetic mutation, in this case for hypertrophic cardiomyopathy, researchers used a technique known as CRISPR-Cas9. The CRISPR-Cas9 technique operates as a sort of ‘molecular scissors’ which can trim away unwanted p...
Source: Mass Device - August 3, 2017 Category: Medical Devices Authors: Fink Densford Tags: Biotech Research & Development Source Type: news

Gene editing used to repair diseased genes in embryos
Conclusion Currently, genetically-inherited conditions like hypertrophic cardiomyopathy cannot be cured, only managed to reduce the risk of sudden cardiac death. For couples where one partner carries the mutated gene, the only option to avoid passing it onto their children is pre-implantation genetic diagnosis. This involves using IVF to create embryos, then testing a cell of the embryo to see whether it carries the healthy or mutated version of the gene. Embryos with healthy versions of the gene are then selected for implantation in the womb. Problems arise if too few or none of the embryos have the correct version of the...
Source: NHS News Feed - August 3, 2017 Category: Consumer Health News Tags: Genetics/stem cells Source Type: news

First human gene editing performed on human embryo
Researchers have successfully used the gene-editing technique CRISPR to correct the gene responsible for hypertrophic cardiomyopathy in a human embryo. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 2, 2017 Category: Consumer Health News Source Type: news

THIS inherited heart condition can cause sudden death - new test could identify risk
HYPERTROPHIC cardiomyopathy is a condition which can cause sudden death. The condition claimed the life of Miles Frost, Sir David Frost's son. (Source: Daily Express - Health)
Source: Daily Express - Health - July 12, 2017 Category: Consumer Health News Source Type: news

Spectrum Health Cardiomyopathy Program named National Center of Excellence
(Spectrum Health) The Spectrum Health Hypertrophic Cardiomyopathy Program has been designated a national Center of Excellence by the Hypertrophic Cardiomyopathy Association (HCMA). Spectrum Health joins 25 other centers with this recognition, and becomes the second center in the state of Michigan. Hypertrophic cardiomyopathy is the most common genetic cardiovascular disorder, and affects at least 1 in 500 people in the United States. HCMA Centers of Excellence are recognized for providing comprehensive diagnostic, treatment, education and research programs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2017 Category: Global & Universal Source Type: news

Brisk Walking Can Help in Hypertrophic Cardiomyopathy Brisk Walking Can Help in Hypertrophic Cardiomyopathy
The study"provides support for a regimen of unsupervised brisk walking 4 to 7 days per week for a minimum of 30 minutes, as a targeted intervention for patients with hypertrophic cardiomyopathy."Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 18, 2017 Category: Cardiology Tags: Cardiology News Source Type: news

Study shows moderate exercise may aid HCM patients
Research suggests a change in current guidelines for people with hypertrophic cardiomyopathy to include moderate exercise. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 17, 2017 Category: Consumer Health News Source Type: news

Moderate exercise may be beneficial for HCM patients
Patients with hypertrophic cardiomyopathy are urged to take it easy. But new research shows they might benefit from moderate aerobic exercise. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 17, 2017 Category: Science Source Type: news

Moderate exercise may be beneficial for HCM patients
(Michigan Medicine - University of Michigan) Patients with hypertrophic cardiomyopathy are urged to take it easy. But new research shows they might benefit from moderate aerobic exercise. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 17, 2017 Category: Global & Universal Source Type: news

Cardiac Symptoms Before Sudden Cardiac Death Caused by HCM Cardiac Symptoms Before Sudden Cardiac Death Caused by HCM
Hypertrophic cardiomyopathy is a frequent cause of sudden cardiac death in young persons. Do most have prior cardiac symptoms? What type of symptoms do they experience?Europace (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2017 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Call to screen for silent killer sudden death gene
Premier League footballer Fabrice Muamba (pictured) collapsed on the pitch in 2012. His heart stopped for 78 minutes and he was diagnosed with hypertrophic cardiomyopathy. (Source: the Mail online | Health)
Source: the Mail online | Health - February 1, 2017 Category: Consumer Health News Source Type: news

Hypertrophic Cardiomyopathy in Afro-Caribbean vs. Caucasians Hypertrophic Cardiomyopathy in Afro-Caribbean vs. Caucasians
How does ethnicity impact the clinical profile and outcomes in hypertrophic cardiomyopathy?Heart (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 13, 2016 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Sep 9 Cardiology News Sep 9 Cardiology News
Trends in infective endocarditis, vein-graft intervention, use of OCT in ACS, hypertrophic cardiomyopathy, and electronic health records are discussed in this week's podcast.theheart.org on Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 9, 2016 Category: Consumer Health News Tags: Cardiology News Source Type: news

Appropriate ICD Therapy in Hypertrophic Cardiomyopathy Appropriate ICD Therapy in Hypertrophic Cardiomyopathy
ICDs are effective at terminating ventricular arrhythmias that cause the majority of sudden cardiac deaths in hypertrophic cardiomyopathy, but is therapy being administered appropriately?Journal of Cardiovascular Electrophysiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 2, 2016 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Heart Metabolics begins Phase IIb trial of perhexiline to treat HCM
Irish biopharmaceutical company Heart Metabolics has begun its Phase IIb trial of perhexiline to treat hypertrophic cardiomyopathy (HCM) and moderate-to-severe heart failure with preserved left ventricular function. (Source: Drug Development Technology)
Source: Drug Development Technology - September 1, 2016 Category: Pharmaceuticals Source Type: news