Associations of Prenatal Urinary Bisphenol A Concentrations with Child Behaviors and Cognitive Abilities

Conclusion: Prenatal urinary BPA concentration was associated with some aspects of child behavior in this cohort, and some associations were stronger among boys. Received: 18 August 2016 Revised: 09 December 2016 Accepted: 12 December 2016 Published: 16 June 2017 Address correspondence to Joseph M. Braun, Department of Epidemiology, Box G-S121-2, Brown University, Providence, RI 02912 USA. Telephone: (401) 863-5397. E-mail: Supplemental Material is available online ( The authors declare they have no actual or potential competing financial interests. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact Our staff will work with you to assess and meet your accessibility needs within 3 working days. Supplemental Material PDF (386 KB) Note to readers with disabilities: EHP has provided a 508-conformant table of contents summarizing the Supplemental Material for this article (see below) so readers with disabilities may determine whether they wish to access the full, nonconformant Supplemental Material. If you need assistance accessing...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research

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AbstractFrontotemporal dementia (FTD) is a highly heritable group of neurodegenerative disorders, with around 30% of patients having a strong family history. The majority of that heritability is accounted for by autosomal dominant mutations in the chromosome 9 open reading frame 72 (C9orf72), progranulin (GRN), and microtubule-associated protein tau (MAPT) genes, with mutations more rarely seen in a number of other genes. This review will discuss the recent updates in the field of genetic FTD. Age at symptom onset in genetic FTD is variable with recently identified genetic modifiers includingTMEM106B (inGRN carriers partic...
Source: Journal of Neurology - Category: Neurology Source Type: research
AbstractThe possibility that alcohol consumption should be considered as a “protective factor” for Parkinson’s disease (PD) has been suggested by several case–control studies. However, other case–control studies and data from prospective longitudinal cohort studies have been inconclusive. We carried out a systematic review which included all the eligible studies published on PD risk related with alcohol consumption, and conducted a meta-analysis according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. The systematic review was performed using two...
Source: Journal of Neurology - Category: Neurology Source Type: research
ConclusionsALS8 patients present mild executive dysfunction and behavioural changes such as mood disorders, apathy and stereotypic behaviour. Our findings suggest that ALS8 is not a pure motor disorder and it is associated with subtle cognitive and behavioural impairments.
Source: Journal of Neurology - Category: Neurology Source Type: research
CONCLUSIONS: Contrary to earlier reports of lower-quality care, patients with and without mental illness had similar preventive and chronic disease management care quality following medical home implementation. PMID: 31310189 [PubMed - as supplied by publisher]
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
CONCLUSIONS: Notable overlap in eating difficulties, behavioural problems and sensory profiles of children with ARFID, ASD or PE, with more severe aberrations in ARFID (food-responsiveness) and ASD (hypersensitivity and social problems) on specific dimensions, argue for a dimensional approach to improve therapy and management of children with these disorders. PMID: 31310945 [PubMed - as supplied by publisher]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
ConclusionsLanguage delays are highly prevalent in HR-sibs and their representation resembles the language profile of children with ASD. Evaluation of language at the level of phonology, grammar, semantics and pragmatics will detect considerably more children experiencing delayed language than holistic approaches.
Source: Research in Autism Spectrum Disorders - Category: Psychiatry Source Type: research
In this study, we aimed to evaluate the effects of pregnancy on the serum level of HE4. Forty-six singleton pregnant women in the study group and 40 premenopausal women in the control group were included. HE4 and Ca125 levels were measured longitudinally at each trimester of pregnancy in the study group and once in the control group at the recruitment. In total 46, 38 and 33 pregnant patients blood samples were analysed in the first, second and third trimester of pregnancy, respectively. The analysis was performed in 31 of the pregnant patients (31/46, 67.4%) in each trimester of pregnancy. A comparison of the median HE4 l...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Publication date: Available online 17 July 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Fabien Pifferi, Fabienne AujardAbstractThe health benefits of chronic caloric restriction (CR) resulting in lifespan extension are well established in many species and has been recently demonstrated also in non-human primates, but its effects in humans remain to be proven on a long-term basis. CR might be a very efficient anti-aging strategy but its definition and limits must be well understood before envisaging to apply it to human. In this review, we first report and compare the recently issued ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
ConclusionConsidering patients with chronic subdural hematomas our study demonstrated that the significant variables predicting outcome are chronic subdural hematomas occurring secondary to an overdraining ventriculo-peritoneal shunt, a history of seizures, and a low level of consciousness measured by either the Markwalder or the Glasgow Coma Score. Interestingly all of these variables are determined prior to the patient arriving at hospital. Our study highlights the need for early presentation prior to clinical deterioration as the major determinant of outcome.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
We present the findings of a three-phase research project. Findings from the research informs organizations and policymakers on how to provide persons with disabilities better access to HIV/AIDS care. PMID: 31308616 [PubMed - in process]
Source: Ethnicity and Disease - Category: International Medicine & Public Health Tags: Ethn Dis Source Type: research
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