Kenya: Kemsa Laxity, Red Tape Worsen Patients' Pain
[Nation] A weak healthcare system and systemic bureaucracy in government institutions has led to the suffering of thousands of terminally-ill patients for close to a year now due to shortage of oral morphine. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 18, 2020 Category: African Health Source Type: news

More than half of US opioid prescriptions for dental procedures exceeded 3-day supply recommendations from CDC 2016 guidelines
New largescale study in the American Journal of Preventive Medicine found overprescription of opioids by dentists common, particularly to patients at high risk for substance abuse, and that almost 1/3 of patients received more powerful drugs than neededElsevierIMAGE: In this cross-sectional analysis of 542,958 dental visits by adult patients, between 1 in 4 and 1 in 2 opioid prescriptions exceeded the recommended morphine equivalents and days'supply for...viewmore Credit: Michelle S. Woods Ann Arbor, February 4, 2020 - Dentists are among top prescribers of opioids in the US, however, whether their opioid prescrib...
Source: Dental Technology Blog - February 13, 2020 Category: Dentistry Source Type: news

'Painkillers should be renamed pain relievers to prevent people from taking a higher dose'
Medical experts argue that misconception that pain will be completely 'killed' makes people believe they should increase their dose. This is helping drive Britain's overuse of opioids such as morphine. (Source: the Mail online | Health)
Source: the Mail online | Health - February 6, 2020 Category: Consumer Health News Source Type: news

Duramorph (Morphine Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 5, 2020 Category: Drugs & Pharmacology Source Type: news

Re-engineered plant compound treats opioid addiction in mice
(American Chemical Society) The abuse of prescription and illegal opioids, such as morphine and heroin, is a major problem in the US, with devastating public health, economic and social consequences. That's why scientists are searching for new medicines to help break the cycle of addiction. Now, researchers reporting in ACS' Journal of Medicinal Chemistry have re-engineered the structure of vincamine, a plant-derived compound, so that it reduces morphine-seeking behaviors in mice.   (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2020 Category: International Medicine & Public Health Source Type: news

German nurse in morphine babies case freed after test mix-up
Prosecutors say a nurse at a German hospital who was arrested on suspicion of administering morphine to five young babies has been released after new tests showed that investigators' initial findings were wrong (Source: ABC News: Health)
Source: ABC News: Health - February 4, 2020 Category: Consumer Health News Tags: Health Source Type: news

Nurse in Germany Charged With Attempted Killing of Five Babies Nurse in Germany Charged With Attempted Killing of Five Babies
Authorities in southwestern Germany detained an intensive care nurse on Wednesday, suspecting that she had attempted to kill five newborn babies in her charge with morphine, police in the city of Ulm said.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - February 1, 2020 Category: Intensive Care Tags: Pediatrics News Source Type: news

Abuse-deterrent formulation of morphine saves healthcare costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - February 1, 2020 Category: Drugs & Pharmacology Source Type: news

Germany: nurse suspected of drugging 5 babies with morphine
Officials say a nurse at a German hospital has been arrested on suspicion that she administered morphine to five young babies shortly before Christmas (Source: ABC News: Health)
Source: ABC News: Health - January 30, 2020 Category: Consumer Health News Tags: Health Source Type: news

More Concern Over Morphine, Clopidogrel Interaction in ACS More Concern Over Morphine, Clopidogrel Interaction in ACS
New data suggest use of morphine delays the absorption of clopidogrel and leads to an increase in short-term cardiac ischemic events.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - January 23, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Former ER Nurse Sentenced to 60 Months in Prison for Fraudulently Obtaining, Tampering with Patient Drugs
Elet Neilson, Layton UT, emergency room, ER, nurse, tampering, personal use, diversion, infect Hep C, McKay-Dee Hospital, Ogden UT, hydromorphone, morphine, intravenous opioid, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - January 14, 2020 Category: Medical Law Authors: DOJ Source Type: news

Fentanyl deaths on rise in UK, drug report warns
The painkiller is said to be up to 100 times stronger than morphine and is entering UK markets. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 4, 2020 Category: Consumer Health News Source Type: news

Rwanda avoids US-style opioids crisis by making own morphine
Rwanda doesn't have access to costly opioids from big pharmaceutical companies, so the African country has come up with a solution (Source: ABC News: Health)
Source: ABC News: Health - December 28, 2019 Category: Consumer Health News Tags: Health Source Type: news

Sustained-Release Morphine Safe in Chronic Breathlessness Sustained-Release Morphine Safe in Chronic Breathlessness
Regular low-dose sustained-release oral morphine appears to be a safe treatment for chronic breathlessness, according to findings from a randomized clinical trial.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - December 27, 2019 Category: Intensive Care Tags: Family Medicine/Primary Care News Source Type: news

Rwanda makes own morphine while U.S. awash with opioids
As thousands die from opioid addiction in America, millions deal with untreated pain in the world's poorest nations. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - December 27, 2019 Category: Consumer Health News Source Type: news

Rwanda avoids US-style opioids crisis by making own morphine
Rwanda doesn't have access to costly opioids from big pharmaceutical companies, so the African country has come up with a solution (Source: ABC News: Health)
Source: ABC News: Health - December 25, 2019 Category: Consumer Health News Tags: Health Source Type: news

Haverhill Woman Sentenced for Drug Tampering
Lauren Perrin, Practical Nurse, Haverhill MA, Drug Tampering, Guilty Plea, Schedule II Controlled Substance, Morphine, Pain Relief, Hospice Patient, Maplewood Care and Rehabilitation Center, Amesbury MA, lowered potency (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - December 19, 2019 Category: Medical Law Authors: DOJ Source Type: news

Pharmacist Admits Tampering with Infusion Narcotics
Carl Mancini, Wolcott CT, Guilty Plea, Tampering, Pharmacist, Home Intravenous Infusions, Hospice Care Intravenous Infusions, Intravenous Infusions, Pain Management, Formulating Infusions, Workplace, Vials, Hydromorphone Hydrochloride, Morphine Sulfate Pentahydrate, Syringe, Saline, Crimping, Reseal (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - December 17, 2019 Category: Medical Law Authors: DOJ Source Type: news

Chronic opioid treatment may raise risk of post-traumatic stress disorder, study finds
While opioids are often prescribed to treat people with trauma-related pain, a new UCLA-led study suggests doctors should use caution before prescribing the drug to those they believe may experience severe stress in the future, in order to reduce the risk the patient will develop PTSD.In the study, researchers administered doses of the opioid morphine to a group of 22 mice for one week, then gave the mice relatively strong foot shocks. After the morphine wore off, the mice were given mild electric foot shocks. These mice showed a substantially longer “freezing response” than a second, control group of 24 mice t...
Source: UCLA Newsroom: Health Sciences - December 3, 2019 Category: Universities & Medical Training Source Type: news

Chronic opioid treatment may increase PTSD risk
(Springer) Long-term (chronic) treatment with opioids, such as morphine, prior to trauma enhances fear learning in mice, according to a study published in Neuropsychopharmacology. The findings, which link chronic opioid treatment before a traumatic event with responses to subsequent stressful events, may suggest a possible mechanism underlying the frequent co-occurrence of post-traumatic stress disorder (PTSD) and opioid dependence. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 1, 2019 Category: International Medicine & Public Health Source Type: news

Fighting opioids with an unlikely supplemental painkiller: Anti-itch medicine
(West Virginia University) West Virginia University researcher Shane Kaski is investigating whether an anti-itch medication that targets a specific part of our nerve cells can make morphine -- which targets a different part--more effective. His findings suggest it can. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2019 Category: International Medicine & Public Health Source Type: news

News: No Reason to Choose Tramadol over Morphine
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - November 1, 2019 Category: Emergency Medicine Tags: News Source Type: news

How the Ban on Medical Advertising Hurt Women Doctors
This article was published on JSTOR Daily, read the original article here. (Source: TIME: Health)
Source: TIME: Health - October 16, 2019 Category: Consumer Health News Authors: Olivia Campbell / JSTOR Daily Tags: Uncategorized health medicine onetime syndication Source Type: news

Registered Nurse Indicted on Drug Diversion Charge
Brianna Duffy, Haverhill MA, Hunt Nursing and Rehab, Danvers MA, morphine sulfate, hospice, patient, Maplewood Care and Rehabilitation Center, Amesbury MA, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - October 11, 2019 Category: Medical Law Authors: DOJ Source Type: news

Former Dracut Nurse Pleads Guilty to Tampering with Liquid Morphine
Michael Langlois, registered nurse, elderly hospice patients, Lowell MA nursing home, saline, Benadryl, Melrose MA nursing home, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - October 7, 2019 Category: Medical Law Authors: DOJ Source Type: news

Researchers Develop New Opioid Detection Breath Test
(CBS) – Breathalyzer tests have been around for years to help identify drunk drivers, but soon there could soon be a similar test for opioids. Engineers and physicians at the University of California, Davis have developed a test that can detect opioids in the exhaled breath of patients taking pain medications like morphine and oxycodone. They hope to eventually have a real time test which could help doctors and nurses determine whether patients with chronic pain are taking their medications properly, and also to check for illegal drug use. The team is also working on similar breath-based tests that could screen ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 7, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated Local Confronting The Crisis opioids Source Type: news

New Breath Test Detects Opioid Use
Researchers at the University of California, Davis have developed an interesting way to combat the opioid crisis. The group, comprised of engineers and physicians, have developed a test that can detect opioid drugs in exhaled breath. "There are a few ways we think this could impact society," Professor Cristina Davis, chair of the Department of Mechanical and Aerospace Engineering at UC Davis, who led the research along with Professor Michael Schivo from the UC Davis Medical Center, said in a release. The work is described in a paper published in the Journal of Breath Research Oct. 3. Doctors and nurses treating c...
Source: MDDI - October 5, 2019 Category: Medical Devices Authors: MDDI Staff Tags: IVD Source Type: news

Haverhill Nurse Pleads Guilty to Drug Tampering
Lauren Perrin, morphine, licensed practical nurse, LPN, Maplewood Care and Rehabilitation Center, Amesbury MA, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - October 4, 2019 Category: Medical Law Authors: DOJ Source Type: news

10 people in one Ohio county fatally overdose on drugs likely laced with fentanyl in just 26 HOURS
10 unnamed people in Franklin County, Ohio, overdosed over 26 hours, according to the Coroner's Office. It may be linked to fentanyl, the synthetic opioids 100 times stronger than morphine. (Source: the Mail online | Health)
Source: the Mail online | Health - September 30, 2019 Category: Consumer Health News Source Type: news

Genetic behavioral screen identifies an orphan anti-opioid system
Opioids target the μ-opioid receptor (MOR) to produce unrivaled pain management, but their addictive properties can lead to severe abuse. We developed a whole-animal behavioral platform for unbiased discovery of genes influencing opioid responsiveness. Using forward genetics in Caenorhabditis elegans, we identified a conserved orphan receptor, GPR139, with anti-opioid activity. GPR139 is coexpressed with MOR in opioid-sensitive brain circuits, binds to MOR, and inhibits signaling to heterotrimeric guanine nucleotide–binding proteins (G proteins). Deletion of GPR139 in mice enhanced opioid-induced inhibition of neu...
Source: ScienceNOW - September 19, 2019 Category: Science Authors: Wang, D., Stoveken, H. M., Zucca, S., Dao, M., Orlandi, C., Song, C., Masuho, I., Johnston, C., Opperman, K. J., Giles, A. C., Gill, M. S., Lundquist, E. A., Grill, B., Martemyanov, K. A. Tags: Cell Biology, Neuroscience r-articles Source Type: news

Prevention of Nausea, Vomiting After Abdominal Hysterectomy Prevention of Nausea, Vomiting After Abdominal Hysterectomy
Postoperative nausea and vomiting is common with intrathecal morphine use in total abdominal hysterectomy. Which antiemetic is most effective for these patients?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 18, 2019 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Dishing out more drugs won ’t stop the pain. Doctors need new tools | Ann Robinson
As a GP, I know opioids have their place. But we shouldn ’t be complacent about a US-style crisis happening in BritainGrowing concern about the prescription of drugs that cause dependence has been backed up by a recent report from Public Health England (PHE). The agencydiscovered that in 2017-18, 13% of adults in England received at least one prescription for opioids such as morphine or oxycodone (although this represented a slight downturn in prescribing after a long upward trend). Other drug classes were implicated too, with 25% of adults prescribed one or more of the following drugs: benzodiazepines (such as Valiu...
Source: Guardian Unlimited Science - September 15, 2019 Category: Science Authors: Ann Robinson Tags: Opioids GPs NHS Doctors Health Society Drugs policy Politics Science UK news Source Type: news

Rx Size Predicts Persistent Opioid Use After Cardiothoracic Surgery
Patients prescribed more than 450 oral morphine equivalents have more new persistent opioid use (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - August 22, 2019 Category: Respiratory Medicine Tags: Cardiology, Pharmacy, Pulmonology, Surgery, Anesthesiology & amp; Pain, Geriatrics, Journal, Source Type: news

Opioid-free Anesthesia and Post-op Period in Cardiac Surgery Opioid-free Anesthesia and Post-op Period in Cardiac Surgery
What impact might an opioid-free anesthesia protocol in cardiac surgery have on post-operative morphine consumption, ICU stay, and outcome?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 16, 2019 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Vital signs: Pharmacy-based naloxone dispensing - United States, 2012-2018 - Guy GP, Haegerich TM, Evans ME, Losby JL, Young R, Jones CM.
BACKGROUND: The CDC Guideline for Prescribing Opioids for Chronic Pain recommends considering prescribing naloxone when factors that increase risk for overdose are present (e.g., history of overdose or substance use disorder, opioid dosages ≥50 morphine ... (Source: SafetyLit)
Source: SafetyLit - August 10, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Intranasal Sufentanil Effective for Acute Severe Trauma Pain Intranasal Sufentanil Effective for Acute Severe Trauma Pain
Intranasal sufentanil is as effective as intravenous morphine for treating acute severe trauma pain, according to results from a noninferiority study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - July 17, 2019 Category: Surgery Tags: Anesthesiology News Source Type: news

Intranasal Sufentanil Cuts Acute Trauma Pain Treated in the ED
WEDNESDAY, July 17, 2019 -- Intranasal sufentanil (INS) is comparable to intravenous morphine (IVM) for acute severe trauma pain treated in the emergency department, according to a study published online July 16 in PLOS Medicine. Marc Blancher,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 17, 2019 Category: Pharmaceuticals Source Type: news

DOJ pushes to close loophole for knock-off fentanyl
Fentanyl, a synthetic opioid, is about 100 times stronger than morphine, and its analogues can be even more potent (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - July 2, 2019 Category: Consumer Health News Source Type: news

Benzodiazepine use with opioids intensifies neonatal abstinence syndrome
(Vanderbilt University Medical Center) Babies born after being exposed to both opioids and benzodiazepines before birth are more likely to have severe drug withdrawal, requiring medications like morphine for treatment, compared to infants exposed to opioids alone, according to a Vanderbilt University Medical Center study published in Hospital Pediatrics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 1, 2019 Category: International Medicine & Public Health Source Type: news

Former Dracut Nurse Pleads Guilty to Tampering with Liquid Morphine
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - June 20, 2019 Category: Drugs & Pharmacology Authors: DOJ Source Type: news

New opioid speeds up recovery without increasing pain sensitivity or risk of chronic pain
(Tulane University) A new type of non-addictive opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System accelerates recovery time from pain compared to morphine without increasing pain sensitivity, according to a new study published in the Journal of Neuroinflammation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 21, 2019 Category: International Medicine & Public Health Source Type: news

March 30, 2018: KC Paramedic Indicted for Stealing Fentanyl, Morphine from Ambulances
(Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - May 16, 2019 Category: Medical Law Authors: u.s. Department of Justice Source Type: news

Paracetamol Plus Ibuprofen Significantly Reduces Morphine Consumption After Hip Arthroplasty
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - May 16, 2019 Category: Orthopaedics Tags: Perspective Source Type: news

Kenya: Report - Shalom Hospital Flouted Patient Care Procedures
[Nation] Shalom Hospital, the facility in which a seven-month old bay died due to an overdose of morphine injection, has been violating several patient care procedures, a report has revealed. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 13, 2019 Category: African Health Source Type: news

Kenya: Cancer Drug Linked to Baby's Death at Shalom Hospital
[Nation] Morphine, a drug usually administered to cancer patients to relieve pain is suspected to have killed a seven-month-old baby at Shalom Community Hospital on Sunday. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 7, 2019 Category: African Health Source Type: news

Tanzania: Morphine Is Coming Around Again to Tanzania
[East African] Tanzania has said a new consignment of morphine will be available this month. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 22, 2019 Category: African Health Source Type: news

Peripheral Nerve Block May Cut Opioid Use After Amputation
WEDNESDAY, April 10, 2019 -- Peripheral nerve blockade with regular local anesthetic and liposomal bupivacaine is associated with lower oral morphine equivalent (OME) use at 72 hours after major lower extremity amputation (MLEA), according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 10, 2019 Category: Pharmaceuticals Source Type: news

TRPV1 promotes opioid analgesia during inflammation
Pain and inflammation are inherently linked responses to injury, infection, or chronic diseases. Given that acute inflammation in humans or mice enhances the analgesic properties of opioids, there is much interest in determining the inflammatory transducers that prime opioid receptor signaling in primary afferent nociceptors. Here, we found that activation of the transient receptor potential vanilloid type 1 (TRPV1) channel stimulated a mitogen-activated protein kinase (MAPK) signaling pathway that was accompanied by the shuttling of the scaffold protein β-arrestin2 to the nucleus. The nuclear translocation of β-...
Source: Signal Transduction Knowledge Environment - April 2, 2019 Category: Science Authors: Basso, L., Aboushousha, R., Fan, C. Y., Iftinca, M., Melo, H., Flynn, R., Agosti, F., Hollenberg, M. D., Thompson, R., Bourinet, E., Trang, T., Altier, C. Tags: STKE Research Articles Source Type: news

Poppy Seed Overdose Prompts Lawsuit
The parents of a Fayetteville man who died of a morphine overdose after drinking tea he made from poppy seeds he ordered from Amazon are suing the online retailer and Sincerely Nuts Inc. of New York, which marketed and sold the 5-pound bag of poppy seeds. (Source: Arkansas Business - Health Care)
Source: Arkansas Business - Health Care - April 1, 2019 Category: American Health Source Type: news

Tanzania: Tanzania Faces Shortage of Pain-Relieving Morphine
[East African] Tanzania is running out of morphine -- a key reliever of severe pain for patients with terminal illnesses. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 27, 2019 Category: African Health Source Type: news