Genetic Abnormalities Common in Autism-Spectrum Disorder Genetic Abnormalities Common in Autism-Spectrum Disorder
About one in eight children diagnosed with autism-spectrum disorder (ASD) have pathogenic findings after genetic testing, according to a new study.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - September 17, 2020 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news

Cross-lagged model of bullying victimization and mental health problems in children with autism in middle to older childhood - Rodriguez G, Drastal K, Hartley SL.
Youth with autism spectrum conditions have been shown to be at an increased risk for bullying victimization. The overall aim of this study was to identify factors associated with increased risk for bullying victimization in youth with autism during middle ... (Source: SafetyLit)
Source: SafetyLit - September 17, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Alleged computer hacker Lauri Love: Living with my autism
Alleged computer hacker Lauri Love won his appeal against extradition and his autism was cited as a factor. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 13, 2020 Category: Consumer Health News Source Type: news

New data further reinforce Roche ’s OCREVUS (ocrelizumab) as a highly effective treatment for people with multiple sclerosis
Basel, 11 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new data that show OCREVUS® (ocrelizumab) is a highly effective treatment option for people with relapsing-remitting multiple sclerosis (RRMS) who experienced a suboptimal response to their prior disease modifying therapy (DMT). Subgroup analys is from the two-year open-label Phase IIIb CASTING study also demonstrates that patients benefit across a wide range of disease related and demographic subgroups, regardless of prior treatment background. Findings will be presented at MSVirtual2020, the 8th Joint Meeting of the Americas Committee...
Source: Roche Media News - September 11, 2020 Category: Pharmaceuticals Source Type: news

New data further reinforce Roche ’s OCREVUS (ocrelizumab) as a highly effective treatment for people with multiple sclerosis
Basel, 11 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new data that show OCREVUS® (ocrelizumab) is a highly effective treatment option for people with relapsing-remitting multiple sclerosis (RRMS) who experienced a suboptimal response to their prior disease modifying therapy (DMT). Subgroup analys is from the two-year open-label Phase IIIb CASTING study also demonstrates that patients benefit across a wide range of disease related and demographic subgroups, regardless of prior treatment background. Findings will be presented at MSVirtual2020, the 8th Joint Meeting of the Americas Committee...
Source: Roche Investor Update - September 11, 2020 Category: Pharmaceuticals Source Type: news

The Great Vaccine Race: Inside the Unprecedented Scramble to Immunize the World Against COVID-19
The cleverest of enemies thrive on surprise attacks. Viruses—and coronaviruses in particular—know this well. Remaining hidden in animal hosts for decades, they mutate steadily, sometimes serendipitously morphing into more effective and efficient infectious agents. When a strain with just the right combination of genetic codes that spell trouble for people makes the leap from animal to human, the ambush begins. Such was the case with SARS-CoV-2, the coronavirus behind COVID-19, and the attack was mostly silent and insidious at first. Many people infected with SARS-CoV-2 remained oblivious as they served as the v...
Source: TIME: Health - September 10, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Magazine Source Type: news

New data show Roche ’s ENSPRYNG (satralizumab) significantly reduces severity and risk of relapse in neuromyelitis optica spectrum disorder (NMOSD)
Basel, 10 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) will present new ENSPRYNG ® (satralizumab) data on reducing relapse severity in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare disease of the central nervous system. These data are being presented at MSVirtual2020, the 8th joint ACTRIMS-ECTRIMS meeting, in addition to longer-term efficacy data supporting the continued effect of ENSPRYNG on reducing the risk of NMOSD relapse, as well as its favourable benefit:risk profile.“The data for ENSPRYNG at MSVirtual2020 are promising and suggest it significantly reduces relapse severity ...
Source: Roche Media News - September 10, 2020 Category: Pharmaceuticals Source Type: news

New data show Roche ’s ENSPRYNG (satralizumab) significantly reduces severity and risk of relapse in neuromyelitis optica spectrum disorder (NMOSD)
Basel, 10 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) will present new ENSPRYNG ® (satralizumab) data on reducing relapse severity in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare disease of the central nervous system. These data are being presented at MSVirtual2020, the 8th joint ACTRIMS-ECTRIMS meeting, in addition to longer-term efficacy data supporting the continued effect of ENSPRYNG on reducing the risk of NMOSD relapse, as well as its favourable benefit:risk profile.“The data for ENSPRYNG at MSVirtual2020 are promising and suggest it significantly reduces relapse severity ...
Source: Roche Investor Update - September 10, 2020 Category: Pharmaceuticals Source Type: news

Autistic adults have a higher rate of physical health conditions
(University of Cambridge) Autistic individuals are more likely to have chronic physical health conditions, particularly heart, lung, and diabetic conditions, according to a new study by researchers at the University of Cambridge. The results are published in the journal Autism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 10, 2020 Category: International Medicine & Public Health Source Type: news

FABP4: Preschool-aged biomarker discovered for autism spectrum disorder
(RIKEN) Researchers at the RIKEN Center for Brain Science in Japan have discovered a biomarker that can detect autism spectrum disorder (ASD) in preschool-aged children. The new study found that levels of the protein FABP4 were much lower in four- to six-year-old children with ASD than they were in other typically developing children. Experiments in mice that lacked FABP4 revealed changes in neurons that resemble those found in the postmortem brains of people with ASD. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 10, 2020 Category: International Medicine & Public Health Source Type: news

Roche expands its multiple sclerosis portfolio with investigational BTK inhibitor fenebrutinib and initiates novel clinical trials for OCREVUS (ocrelizumab)
Basel, 9 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced the initiation of an innovative Phase III clinical trial programme for its investigational medicine fenebrutinib in multiple sclerosis (MS), along with a higher-dose Phase III clinical trial programme for OCREVUS® (ocrelizumab) and a distinct O CREVUS trial specifically to support African-American and Hispanic- and Latinx-American patients with MS. Overviews of clinical trials and scientific rationale will be presented at MSVirtual2020, the 8th Joint Meeting of the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTR...
Source: Roche Media News - September 9, 2020 Category: Pharmaceuticals Source Type: news

Roche expands its multiple sclerosis portfolio with investigational BTK inhibitor fenebrutinib and initiates novel clinical trials for OCREVUS (ocrelizumab)
Basel, 9 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced the initiation of an innovative Phase III clinical trial programme for its investigational medicine fenebrutinib in multiple sclerosis (MS), along with a higher-dose Phase III clinical trial programme for OCREVUS® (ocrelizumab) and a distinct O CREVUS trial specifically to support African-American and Hispanic- and Latinx-American patients with MS. Overviews of clinical trials and scientific rationale will be presented at MSVirtual2020, the 8th Joint Meeting of the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTR...
Source: Roche Investor Update - September 9, 2020 Category: Pharmaceuticals Source Type: news

Advancing our understanding of self-harm, suicidal thoughts and behaviours in autism - Cassidy SA, Robertson A, Townsend E, O'Connor RC, Rodgers J.
Until recently, self-harm, suicidal thoughts and behaviours have not received extensive attention in autism research (Cassidy 2020; Cassidy and Rodgers 2017). The extant research evidence indicates high rates of self-harm in autistic people, but this work ... (Source: SafetyLit)
Source: SafetyLit - September 7, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Development of the parental self-efficacy scale for preventing challenging behaviors in children with autism spectrum disorder - Kabashima Y, Tadaka E, Arimoto A.
BACKGROUND: Almost all children with autism spectrum disorder (ASD) have experienced challenging behavior, including disruptive and aggressive behavior symptoms to both themselves and others. In conjunction with appropriate strategic parenting, challenging... (Source: SafetyLit)
Source: SafetyLit - September 7, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Yale researchers find a cause and possible treatment for Fragile X
Fragile X syndrome — a disorder of the X chromosome — is the leading cause of autism and the primary genetic driver of intellectual disability. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 3, 2020 Category: Universities & Medical Training Source Type: news

Meeting the needs of people with a learning disability and autistic people, NHS Providers (published August 2020)
Based on extensive interviews with the leaders of seven trusts in the NHS, this report sets out in detail the common themes behind high-quality care, offering detailed case studies of how these services have succeeded. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 3, 2020 Category: Consumer Health News Source Type: news

Getting it right for everyone: meeting the needs of people with a learning disability and autistic people in NHS services
Based on extensive interviews with the leaders of seven trusts in the NHS providing good or outstanding care to people with a learning disability and people with autism, and broader ongoing engagement with trusts providing these services, this report sets out in detail the common themes behind high-quality care, offering detailed case studies of how these services have succeeded. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 2, 2020 Category: Consumer Health News Source Type: news

The Role of Structural Racism in Delayed Autism Diagnoses The Role of Structural Racism in Delayed Autism Diagnoses
This study the need to further understand – and act on – the disproportionate burden of intellectual disability comorbidity among these children, the investigators say.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - September 2, 2020 Category: Psychiatry Tags: Pediatrics News Source Type: news

Prenatal Flu Vaccination Not Linked to Autism in Children Prenatal Flu Vaccination Not Linked to Autism in Children
Children exposed to the influenza A(H1H1)pdm09 vaccine in utero were no more likely to develop autism than children whose mothers were not vaccinated during pregnancy, a study has found.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - September 2, 2020 Category: Infectious Diseases Tags: Pediatrics News Source Type: news

Prenatal Flu Shot Not Linked to Autism in Kids
Prenatal Flu Vaccination Not Linked to Autism in Children (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - September 2, 2020 Category: General Medicine Source Type: news

Guilt by dissociation: Study sheds light on serotonin in autism
(Florida Atlantic University) A study on serotonin, a mood-regulating molecule in the brain that regulates many brain synapses, is helping to unravel the puzzle surrounding its role in autism. The activity and regulation of the serotonin transporter (SERT), protein is critically dependent on a number of other proteins that tell the protein where to locate on nerve cells and how to act. Shifts in the transporter's activity can significantly impact the ability of serotonin to act in the brain. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 2, 2020 Category: International Medicine & Public Health Source Type: news

Meeting the needs of people with a learning disability and autistic people
Based on extensive interviews with the leaders of seven trusts in the NHS providing good or outstanding care to people with a learning disability and people with autism, and broader ongoing engagement with trusts providing these services, this report sets out in detail the common themes behind high-quality care, offering detailed case studies of how these services have succeeded. (Source: NHS Networks)
Source: NHS Networks - September 2, 2020 Category: UK Health Source Type: news

Maternal H1N1 Flu Vaccination Not Linked to Autism in Offspring
Prenatal exposure not associated with diagnosis of autism spectrum disorder, autistic disorder (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - September 1, 2020 Category: Psychiatry Tags: Family Medicine, Gynecology, Infections, Internal Medicine, Neurology, Nursing, Pediatrics, Pharmacy, Psychiatry, Journal, Source Type: news

Maternal H1N1 Flu Vaccination Not Linked to Autism in Offspring
TUESDAY, Sept. 1, 2020 -- Maternal influenza A(H1N1)pdm09 vaccination during pregnancy is not associated with risk for autism spectrum disorder (ASD) in offspring, according to a study published online Sept. 1 in the Annals of Internal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 1, 2020 Category: Pharmaceuticals Source Type: news

Mom-to-Be's Flu Shot Doesn't Raise Autism Risk
TUESDAY, Sept. 1, 2020 -- Pregnant women are understandably worried about everything that goes into their bodies. But here's one worry they can cross off that list: flu shots. A large, new study has confirmed that an expectant woman's flu shot... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 1, 2020 Category: General Medicine Source Type: news

Flu vaccine during pregnancy has NO link to a baby's risk of developing autism, study confirms
Researchers from the Karolinska Institutet in Stockholm, Sweden, studied birth records of 69,000 children born between 2009 and 2010 and found autism was lower in the vaccine group. (Source: the Mail online | Health)
Source: the Mail online | Health - September 1, 2020 Category: Consumer Health News Source Type: news

PCOS is linked to increased risk of neuropsychiatric disorders in offspring
(European Society of Human Reproduction and Embryology) Children born to mothers with polycystic ovary syndrome (PCOS) are at greater risk of a wide range of psychiatric and neurodevelopmental disorders, according to new research published in Human Reproduction. The study is the first to show links between PCOS and such a wide range of disorders, which include emotional and behavioural problems, delayed development, learning, speech and language problems, autism and attention deficit hyperactivity disorder (ADHD). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 31, 2020 Category: International Medicine & Public Health Source Type: news

Israeli Officer Need Not Have Shot Autistic Palestinian, Commander Says: The commander testified that the man his partner killed, Iyad...
The commander testified that the man his partner killed, Iyad al-Hallaq, was not resisting and posed no danger, in a case that ignited... (Source: Reuters: Health)
Source: Reuters: Health - August 28, 2020 Category: Consumer Health News Source Type: news

Physiological test for autism proves effective independent of co-occurring conditions
(Rensselaer Polytechnic Institute) Developing a physiological test for diagnosing autism spectrum disorder (ASD), one that measures certain components in the blood, has the potential to be a paradigm shift for diagnosing ASD. However, the large heterogeneity of how ASD affects individuals has long been viewed as a key obstacle to the development of such a test. Research conducted at Rensselaer Polytechnic Institute, and published online today in the journal Research in Autism Spectrum Disorders, represents a significant step toward addressing this challenge. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 28, 2020 Category: Biology Source Type: news

Genetic link between cattle temperament and autism
(University of Queensland) Researchers have discovered that cattle share an overlap of genes with humans that are critical in brain function and response to fear stimuli. The results open the way for research conducted on behavioural traits in humans to shed further light on temperament in cattle. The study confirms that temperament has a significant genetic basis in cattle - around 35 per cent - and it is the first time a whole genome sequence has been used to analyse temperament in cattle. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 27, 2020 Category: International Medicine & Public Health Source Type: news

‘Missed opportunities’ in management of troubled service, review finds
Several “missed opportunities” by local commissioners to tackle problems within a troubled autism service have been identified by an independent review. (Source: HSJ)
Source: HSJ - August 25, 2020 Category: UK Health Source Type: news

For Black Kids, Autism Caught Late in the Game
That delay means that young Black Americans miss out on early intensive treatment that is essential to help children with autism be better able to deal with school and social life, the researchers said. (Source: WebMD Health)
Source: WebMD Health - August 24, 2020 Category: Consumer Health News Source Type: news

For Black Children With Autism, Diagnosis Occurs at About Age 5
On average, diagnosis occurs 3.5 years after parents'first concerns about the child's development (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - August 24, 2020 Category: Psychiatry Tags: Family Medicine, Neurology, Nursing, Pediatrics, Psychiatry, Journal, Source Type: news

For Black Kids, Autism Caught Late in the Game
MONDAY, Aug. 24, 2020 -- It takes close to three years for a Black preschooler with autism to get a definitive diagnosis, a new U.S. study finds. That delay means that young Black Americans miss out on early intensive treatment that is essential to... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 24, 2020 Category: General Medicine Source Type: news

For Black Children With Autism, Diagnosis Occurs at About Age 5
MONDAY, Aug. 24, 2020 -- Diagnosis of African American children with autism spectrum disorder (ASD) occurs at an average of 64.9 months, many months after parents'first concerns about their child's development, according to a study published online... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 24, 2020 Category: Pharmaceuticals Source Type: news

Autistic people's nerve cells differ before birth
(Elsevier) A new study now shows in human brain cells that Autism, a neurodevelopmental condition, can now be traced back to prenatal development, even though the disorder is not diagnosed until at least 18 months of age. The atypical development starts at the very earliest stages of brain organization, at the level of individual brain cells, according to scientists at King's College London and Cambridge University, UK. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 24, 2020 Category: International Medicine & Public Health Source Type: news

Simple test could improve public attitudes to autism
(University of Bath) Psychologists from Bath and Essex suggest existing ways of testing public attitudes towards autism are not fit for purpose. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 21, 2020 Category: International Medicine & Public Health Source Type: news

Independent community mobility and driving experiences of adults on the autism spectrum: a scoping review - Kersten M, Coxon K, Lee H, Wilson NJ.
IMPORTANCE: Autistic adults face decreased community participation for employment, education, and social activities plus barriers to driving and transportation. However, little is known about their experiences of moving around community environments. O... (Source: SafetyLit)
Source: SafetyLit - August 20, 2020 Category: International Medicine & Public Health Tags: Age: Young Adults Source Type: news

Art show by adults with autism now on display near Upstate Cancer Center
The artists work out of Studio 8 at the Delavan with Jackie Adamo. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - August 20, 2020 Category: Universities & Medical Training Tags: News Source Type: news

Art show by adults with autism now on display at Upstate Cancer Center
The artists work out of Studio 8 at the Delavan with Jackie Adamo. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - August 20, 2020 Category: Universities & Medical Training Tags: News Source Type: news

Give  disabled people the right to work from home after Covid-19, says UNISON    
  Disabled employees work​ing from home during lockdown say they​ have been more productive and took fewer days off sick than when ​they were doing their job​s in the office, according to a survey published today (Wednesday) by UNISON. The union is now calling on the government to give disabled people a new right to work from home if they w​ish and for employers to face penalties if they do​n’t comply. Disabled employees should have the right under equality laws* to ‘reasonable adjustments’ ...
Source: UNISON Health care news - August 19, 2020 Category: UK Health Authors: Sophie Goodchild Tags: News Press release disability home working guide Source Type: news

Swim program pilot for children with autism: impact on behaviors and health - Johnson NL, Bekhet AK, Karenke T, Garnier Villareal M.
The purpose of this mixed methods pre-/post-pilot intervention study was to assess parental psychological health and child challenging behaviors before and after a swimming program for children with autism. Participants were 10 parent-child dyads. Child's ... (Source: SafetyLit)
Source: SafetyLit - August 18, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

A prosocial neuroligin
NLGN3 links oxytocin signaling, protein synthesis, and social behavior in a mouse model of autism. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - August 18, 2020 Category: Science Authors: Ferrarelli, L. K. Tags: STKE Editors ' Choice Source Type: news

Autism-cholesterol link
(Harvard Medical School) Study identifies genetic link between cholesterol alterations and autism. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2020 Category: International Medicine & Public Health Source Type: news

Drexel study: Measuring social networks of young adults with autism
(Drexel University) While social isolation is a core challenge associated with autism, researchers from Drexel University's A.J. Drexel Autism Institute have laid the groundwork to show how interpersonal relationships, and the resources they provide, could impact autistic youth's adult outcomes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 17, 2020 Category: International Medicine & Public Health Source Type: news

Pregnant mother's immunity tied to behavioral, emotional challenges for kids with autism
(University of California - Davis Health) Children with autism born to mothers who had immune conditions during their pregnancy are more likely to have behavioral and emotional problems, a UC Davis Health study has found. Offspring sex may also interact with maternal immune conditions to influence outcomes, particularly in terms of a child's cognition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2020 Category: International Medicine & Public Health Source Type: news

Timing of diagnosis, depression and self-harm in adolescents with autism spectrum disorder - Hosozawa M, Sacker A, Cable N.
This exploratory study aimed to explore the association between depression and self-harming behaviour in adolescence and the timing of diagnosis for autism spectrum disorder. We analysed data on 11,320 14  year olds, including 396 children with autism spe... (Source: SafetyLit)
Source: SafetyLit - August 13, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Brief report: predictors of school refusal due to bullying in children with autism spectrum disorder and attention-deficit/hyperactivity disorder - McClemont AJ, Morton HE, Gillis JM, Romanczyk RG.
This study exa... (Source: SafetyLit)
Source: SafetyLit - August 13, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Developing community mobility and driving with youth on the autism spectrum: a psychosocial perspective - Kersten ML, Coxon K, Lee H, Wilson NJ.
BACKGROUND: Youth on the autism spectrum face particular challenges with community mobility and driving, contributing to reduced community participation. Skill development may be uniquely shaped by complex interactions between autistic traits, psychosocial... (Source: SafetyLit)
Source: SafetyLit - August 13, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

ASD, OCD and violence - a forensic case study - Edwards H, Higham L.
PURPOSE The purpose of this paper is to illustrate the formulation and psychological treatment of a complex case whereby a combination of autism spectrum disorder (ASD) and obsessive compulsive disorder (OCD) has resulted in violent and aggressive behaviou... (Source: SafetyLit)
Source: SafetyLit - August 13, 2020 Category: International Medicine & Public Health Tags: Violence and Weapons Issues Source Type: news