Constituents of Passiflora incarnata, but Not of Valeriana officinalis, Interact with the Organic Anion Transporting Polypeptides (OATP)2B1 and OATP1A2
Planta Med DOI: 10.1055/a-1305-3936Herbal medication used in the treatment of sleep disorders and anxiety often contain extracts of Valeriana officinalis or Passiflora incarnata. Valerenic acid in V. officinalis and apigenin, orientin, and vitexin in P. incarnata are thought to contribute to their therapeutic effect. It was the aim of this study to test whether these constituents of herbal extracts are interacting with the uptake of estrone 3-sulfate, pregnenolone sulfate, and dehydroepiandrosterone sulfate mediated by the uptake transporters organic anion transporting polypeptide 2B1 (OATP2B1) or organic anion transporti...
Source: Planta Medica - January 28, 2021 Category: Drugs & Pharmacology Authors: Sch äfer, Anima M. Gilgen, Pierrine M. Spirgi, Clara Potterat, Olivier Meyer zu Schwabedissen, Henriette E. Tags: Original Papers Source Type: research
Anti-anxiety properties of selected medicinal plants.
The objective of this review is to provide information about the healing outcomes of anxiety treatment with natural products. Valeriana officinalis, Citrus aurantium, Commelina benghalensis, Achyranthes aspera, Mimosa pudica, Achillea millefolium, Nymphaea alba, Leonurus cardiac, Camellia sinensis, Turnera aphrodisiaca, Crataegus oxyacantha and Piper methysticum showed promising effects on anxiety in animal models. In clinical studies, passion flower, kava, valerian, St John's wort, and ashwagandha showed the most positive results. More studies are needed for the exploration of the anti-anxiety of medicinal plants. In drug...
Source: Current Pharmaceutical Biotechnology - January 22, 2021 Category: Biotechnology Authors: Khan A, Akram M, Thiruvengadam M, Daniyal M, Zakki SA, Munir N, Zainab R, Heydari M, Mosavat SH, Rebezov M, Shariati MA Tags: Curr Pharm Biotechnol Source Type: research
Nutraceuticals for Sleep Disorders.
Abstract
Sleep is considered as one of the most important aspect for maintaining a healthy life. For a person to function normally at least 6-8 hours of sleep daily is necessary. Sleep not only affects our mood, but also regulates the efficiency of work done. Many complications arise due to inadequacy of sleep. The unhealthy food and lifestyle choices have made us more prone to sleep disorders. The medications which are used for the treatment of sleep disorders are mainly habit forming and have tendencies of withdrawal symptoms. This inadequacy in medication has lead to search for newer, better options. Th...
Source: Combinatorial Chemistry and High Throughput Screening - January 20, 2021 Category: Chemistry Authors: Ali R, Tariq S, Kareem O, Fayaz F, Aziz T, Dinesh M, Pottoo FH, Siddiqui N Tags: Comb Chem High Throughput Screen Source Type: research
[ASAP] Correction to The Role of Endogenous Enzymes during Malting of Barley and Wheat Varieties in the Mitigation of Styrene in Wheat Beer
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.0c07142 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - January 19, 2021 Category: Food Science Authors: Valerian Kalb, Torsten Seewald, Thomas Hofmann, and Michael Granvogl Source Type: research
A Review Focused on Molecular Mechanisms of Anxiolytic Effect of Valerina officinalis L. in Connection with Its Phytochemistry through in vitro/in vivo Studies.
Abstract
Valeriana officinalis L. (Valerianaceae) is one of the most reputed ancient medicinal plants used in modern phytotherapy and traditional medicine. Its root extract is one of the most effective herbal sedatives and tranquilizers, where the plant is also used for treatment of gastrointestinal spasms. V. officinalis has a complex phytochemistry consisting of the esterified iridoid derivatives known as valepotriates (e.g. valtrate, didrovaltrate, isovalerenic acid), sesquiterpenes (e.g. valerenic acid), flavonoids (e.g. linarin, apigenin), lignans (e.g. pinoresinol, hydroxypinoresinol), alkaloids (e.g...
Source: Current Pharmaceutical Design - January 18, 2021 Category: Drugs & Pharmacology Authors: Orhan IE Tags: Curr Pharm Des Source Type: research
Combining mechanical and thermal surface Fourier transform analysis to follow the dynamic fatigue behavior of polymers
Publication date: Available online 13 January 2021Source: Polymer TestingAuthor(s): Valerian Hirschberg, Manfred Wilhelm, Denis Rodrigue (Source: Polymer Testing)
Source: Polymer Testing - January 13, 2021 Category: Chemistry Source Type: research
Efficacy of Valerian Extract on Sleep Quality after Coronary Artery bypass Graft Surgery: A Triple-Blind Randomized Controlled Trial
ConclusionThe consumption of oral valerian root extract over 30 nights could significantly improve the patients' sleep quality safely after CABG surgery. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - January 1, 2021 Category: Internal Medicine Source Type: research
Unexpected subdiaphragmatic benign cyst
Turk J Gastroenterol. 2020 Nov;31(11):829-830. doi: 10.5152/tjg.2020.19812.NO ABSTRACTPMID:33361048 | PMC:PMC7759233 | DOI:10.5152/tjg.2020.19812 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - December 28, 2020 Category: Gastroenterology Authors: Melania Macarie Alexandra Pais Calin Molnar Razvan Valerian Opaschi Minodora Maria Șchiopea Zolog Simona Maria B ățagă Ioan Macarie Source Type: research
Unexpected subdiaphragmatic benign cyst
Turk J Gastroenterol. 2020 Nov;31(11):829-830. doi: 10.5152/tjg.2020.19812.NO ABSTRACTPMID:33361048 | PMC:PMC7759233 | DOI:10.5152/tjg.2020.19812 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - December 28, 2020 Category: Gastroenterology Authors: Melania Macarie Alexandra Pais Calin Molnar Razvan Valerian Opaschi Minodora Maria Șchiopea Zolog Simona Maria B ățagă Ioan Macarie Source Type: research
The Effect of an Enhanced Recovery Program on Elective Right Hemicolectomies for Crohn's Disease vs. Colon Cancer: A Retrospective Cohort Analysis.
This study examines the postoperative course of both Crohn's disease (CD) and colon cancer (CC) patients after elective right hemicolectomies and compares the effectiveness of ERAS protocol.
METHODS: A retrospective analysis was performed on patients with CD and CC undergoing elective right hemicolectomies and ileocecectomies from January 2014 through June 2016 (pre-ERAS) and January 2017 through April 2019 (post-ERAS) from a single tertiary care center. Patient demographics and perioperative variables were examined, including prolonged postoperative ileus (PPOI), hospital LOS, and 30-day readmission.
RESUL...
Source: The American Surgeon - December 23, 2020 Category: Surgery Authors: Croasdale DR, Su EM, Olutola OE, Polito CP, Ata A, Keenan M, Valerian BT, David Chismark A, Canete JJ, Lee EC Tags: Am Surg Source Type: research
Discovering latent themes in traffic fatal crash narratives using text mining analytics and network topology
Publication date: February 2021Source: Accident Analysis & Prevention, Volume 150Author(s): Keneth Morgan Kwayu, Valerian Kwigizile, Kevin Lee, Jun-Seok Oh (Source: Accident Analysis and Prevention)
Source: Accident Analysis and Prevention - December 4, 2020 Category: Accident Prevention Source Type: research
Medicinal plants and their preparations in the European market: why has the harmonization failed? The cases of St. John's wort, valerian, ginkgo, ginseng, and green tea
Publication date: Available online 24 November 2020Source: PhytomedicineAuthor(s): Anna Rita Bilia, Maria do Céu Costa (Source: Phytomedicine)
Source: Phytomedicine - November 25, 2020 Category: Drugs & Pharmacology Source Type: research
Phosphate and Methionine Affect Cadmium Uptake in Valerian (Valeriana officinalis L.)
Publication date: Available online 24 November 2020Source: Plant Physiology and BiochemistryAuthor(s): Seyyedeh Atefeh Mousavi, Neda Dalir, Rasoul Rahnemaie, Rainer Schulin (Source: Plant Physiology and Biochemistry)
Source: Plant Physiology and Biochemistry - November 24, 2020 Category: Biochemistry Source Type: research
[ASAP] Correction to Studies on the Impact of Malting and Mashing on the Free, Soluble Ester-Bound, and Insoluble Ester-Bound Forms of Desired and Undesired Phenolic Acids Aiming at Styrene Mitigation during Wheat Beer Brewing
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.0c07140 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - November 18, 2020 Category: Food Science Authors: Valerian Kalb, Torsten Seewald, Thomas Hofmann, and Michael Granvogl Source Type: research
[ASAP] The Role of Endogenous Enzymes during Malting of Barley and Wheat Varieties in the Mitigation of Styrene in Wheat Beer
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.0c04837 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - November 5, 2020 Category: Food Science Authors: Valerian Kalb, Torsten Seewald, Thomas Hofmann, and Michael Granvogl Source Type: research
