Metabolic acidosis in critically ill patients with cirrhosis: Epidemiology and short-term mortality risk factors.
CONCLUSION: Critically ill patients with cirrhosis have a high mortality rate and poor prognosis because of the high prevalence of metabolic acidosis. Lactic acidosis is the worst prognosis of all types of metabolic acidosis. MELD-MA performs well on the short-term mortality assessment in critically ill patients with cirrhosis and metabolic acidosis. PMID: 31633484 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Gao F, Lin MT, Yang XY, Cai MX, Nan H, Xie W, Huang ZM Tags: Turk J Gastroenterol Source Type: research

Covering the Cover.
PMID: 31625930 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Şimşek C Tags: Turk J Gastroenterol Source Type: research

Investigation of JAM-A (rs790056) and LFA-1 (rs8058823) gene variants in Turkish colorectal cancer patients.
an H, Taştekin D Abstract BACKGROUND/AIMS: Lymphocyte function-associated antigen 1 (LFA-1) is a transmembrane glycoprotein expressed on the surface of leukocytes and containing the binding domain for junctional adhesion molecule-A (JAM-A). The aim of the present study was to evaluate the effects of JAM-A and LFA-1 variants on the formation of colorectal cancer and metastasis. MATERIALS AND METHODS: A total of 82 subjects with colorectal cancer and 67 healthy subjects were studied. DNA was isolated from blood samples, and variations were determined using the polymerase chain reaction and restriction fragment...
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Çaykara B, Alsaadoni H, Pençe HH, Pençe S, Yılmaz Aydoğan H, Taştekin D Tags: Turk J Gastroenterol Source Type: research

Impaired thiol/disulfide homeostasis in patients with mild acute pancreatitis.
el Ö Abstract BACKGROUND/AIMS: The aim of this study was to compare the dynamic thiol/disulfide (SS) homeostasis and ischemia-modified albumin (IMA) concentration between healthy subjects and patients with mild acute pancreatitis (AP). MATERIALS AND METHODS: A total of 28 patients with AP (AP group) and 35 age- and sex-matched healthy individuals (control group) were included in this study. Serum thiols/SS and IMA concentrations were measured and compared between the two groups. RESULTS: The mean serum native thiol (SH) and total thiol (TT) levels were significantly lower in the AP group than in the...
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Uyanıkoğlu A, Sabuncu T, Yıldız R, Cindioğlu Ç, Kirmit A, Erel Ö Tags: Turk J Gastroenterol Source Type: research

Palliative resection of primary site in advanced gastroenteropancreatic neuroendocrine tumors improves survivals.
CONCLUSION: Gastroenteropancreatic neuroendocrine tumors with primary site resected had improved survivals when compared to the unresected group. PMID: 31625933 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Kıvrak Salim D, Bayram S, Gömceli İ, Çekin AH, Karaca M, Koçer M, Yıldız M Tags: Turk J Gastroenterol Source Type: research

Determination of the changes on the small intestine of pregnant mice by histological, enzyme histochemical, and immunohistochemical methods.
CONCLUSION: In conclusion, villus parameters, ALP reactivity, and percentage of PCNA-positive cells in the small intestine were affected during pregnancy. PMID: 31625934 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Şensoy E, Öznurlu Y Tags: Turk J Gastroenterol Source Type: research

Rare cause of severe hematemesis due to IgG4-related gastric ulcer.
PMID: 31625935 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: He YQ, Fu X, Chen DF Tags: Turk J Gastroenterol Source Type: research

Necrotizing pancreatitis after removal of prophylactically placed pancreatic stent.
PMID: 31625936 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Sundaram S Tags: Turk J Gastroenterol Source Type: research

Giant hepatic hemangioma: An unusual cause of gastric compression.
lmaz S PMID: 31625937 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Özdemir E, Akbulut S, Kutlutürk K, Yılmaz S Tags: Turk J Gastroenterol Source Type: research

Segmental cytomegalovirus colitis mimicking sigmoid tumor in an immunocompetent patient.
PMID: 31625938 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Santacruz CC, Carlin PS, Rancano RS, Medina LO, Miguel JC Tags: Turk J Gastroenterol Source Type: research

Application of preoperative endoscopic ultrasonography-guided carbon nanoparticle tattooing combined with titanium clip labeling in esophagogastric junction adenocarcinoma.
PMID: 31625939 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Lin L, Wang M, Hong J, Yang S, Wang Y Tags: Turk J Gastroenterol Source Type: research

Neutrophil-to-lymphocyte ratio alone may not be a true indicator of the severity of acute pancreatitis.
i T PMID: 31625940 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Tanoğlu A, Düzenli T Tags: Turk J Gastroenterol Source Type: research

Acute liver failure in adults.
lu M PMID: 31625941 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Authors: Çalışkan AR, Harputluoğlu M Tags: Turk J Gastroenterol Source Type: research

Erratum.
Authors: PMID: 31625942 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Tags: Turk J Gastroenterol Source Type: research

Erratum.
Authors: PMID: 31625943 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - October 1, 2019 Category: Gastroenterology Tags: Turk J Gastroenterol Source Type: research

Covering the Cover.
PMID: 31530519 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Toka B Tags: Turk J Gastroenterol Source Type: research

Usage of HCV viremic organs in liver transplantation to anti-HCV negative recipients: The current status and review of literature.
M, Şimşek C, Gürakar A Abstract Liver transplantation is the main curative therapy for end-stage liver disease. The number of transplanted organs is increasing globally. However, the number of available organs in the pool is insufficient, considering the excessive number of patients on the waiting list, which is a major concern for transplant programs. Hepatitis C infection (HCV) is a common indication for liver transplantation, and in recent years, a major progress has been made in its treatment with direct-acting antiviral (DAA) agents. HCV-positive livers have been transplanted to HCV-positive recipients...
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Çiftçibaşı Örmeci A, Yıldız Ç, Seberi B, Gürakar M, Şimşek C, Gürakar A Tags: Turk J Gastroenterol Source Type: research

Does celiac disease cause autoimmune sensorineural hearing loss?
CONCLUSION: In this study with a higher number of CD patients when compared with the previous studies, it has been shown that CD does not appear to cause autoimmune sensorineural hearing loss. In addition, the status of the patients regarding the activeness or the remission of CD did not display a differ between the CD patients in terms of hearing levels. PMID: 31530521 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Yazıcı A, Yıldırım AE, Konduk BT Tags: Turk J Gastroenterol Source Type: research

Effect of gender on the etiology of fecal incontinence: Retrospective analysis of a tertiary referral center in Turkey.
CONCLUSION: Increasing awareness of labor safety, controlling diabetes mellitus, and preventing obstetric traumas may reduce the prevalence of fecal incontinence. PMID: 31530522 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Tokay Tarhan S, Atuğ Ö, Giral A, İmeryüz N Tags: Turk J Gastroenterol Source Type: research

Gastrointestinal findings in 26 adults with common variable immunodeficiency: The fickle nature of the disease manifests in gastrointestinal biopsies.
avşargil B Abstract BACKGROUND/AIMS: The aim of the present study was to demonstrate the histopathological findings in gastrointestinal (GI) biopsies in adults with common variable immunodeficiency (CVID). MATERIALS AND METHODS: A total of 172 GI biopsies of 26 patients with CVID obtained over a 16-year period were reevaluated. Findings were analyzed using descriptive analyzes and χ2 test. RESULTS: Female-to-male ratio was 1.36. The median age at diagnosis was 36±13.94 (16-72) years. Chronic esophagitis was noted in 3 patients. The absence of plasma cells in the stomach, duodenum, and colon w...
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Pehlivanoğlu B, Ardeniz Ö, Hassoy H, Sezak M, Özdemir H, Ünal NG, Onay H, Doğanavşargil B Tags: Turk J Gastroenterol Source Type: research

Evaluation of depression, anxiety and quality of life in hepatitis C patients who treated with direct acting antiviral agents.
CONCLUSION: Depression got minimally worse in the male group despite an improvement in CHC. Anxiety scores were improved with treatment in the cirrhotic and non-cirrhotic groups significantly. A decrease in anticipatory anxiety may be related to the high treatment success with DAAA. Nearly all the subitems of the QoL scores were improved after treatment and these were more common in the female group. Elimination of HCV may itself decrease the number of patients who need psychiatric treatment. PMID: 31530524 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Kesen O, Kani HT, Yanartaş Ö, Aykut UE, Gök B, Gündüz F, Yılmaz Y, Özdoğan OC, Özen Alahdab Y Tags: Turk J Gastroenterol Source Type: research

The relationship between serum histon levels and the severity of acute pancreatitis.
CONCLUSION: Serum histone levels did not significantly differ between the severe and mild AP groups. Therefore, these markers may not provide additional benefit for determining the severity of AP. PMID: 31530525 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Biberci Keskin E, İnce AT, Sümbül Gültepe B, Köker İH, Şentürk H Tags: Turk J Gastroenterol Source Type: research

May dexpanthenol, platelet-rich plasma, and thymoquinone provide new hope to maintain liver regeneration after partial hepatectomy?
CONCLUSION: Although dexpanthenol did not affect biochemical oxidative parameters, it was considered to have improving effects on liver regeneration histopathologically. In addition, it was thought that PRP may be used for treatment of ischemia-reperfusion injury and cholestatic damage of the liver. Nevertheless, further studies are required on these subjects. PMID: 31530526 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Aydın O, Pehlivanlı F, Karaca G, Aydın G, Altunkaya C, Bulut H Tags: Turk J Gastroenterol Source Type: research

Anti-colon cancer activity of Bifidobacterium metabolites on colon cancer cell line SW742.
CONCLUSION: The study has shown that the regular ingested probiotics could prevent the development of colorectal cancer. During the present study, the produced CFS could inhibit the growth of colon cancer cells. In conclusion, probiotics have good potential to be introduced as a new approach to colon cancer treatment. PMID: 31530527 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Bahmani S, Azarpira N, Moazamian E Tags: Turk J Gastroenterol Source Type: research

What is a disappearing intra-abdominal mass?
PMID: 31530528 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Sahoo AK, Goneppanavar M, Rajan S, Raj R, Prasad N R V Tags: Turk J Gastroenterol Source Type: research

A very rare cause of the intra-abdominal bleeding.
AN PMID: 31530529 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Yücesoy AN Tags: Turk J Gastroenterol Source Type: research

Extraneural metastasis of meningeal haemangiopericytoma to the liver.
PMID: 31530530 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Yusoff AR, Mokhtar S, Raman K, Singh H, Shabery NAM Tags: Turk J Gastroenterol Source Type: research

A rare case of eosinophilic esophagitis and eosinophilic subserosal gastroenteritis with ascites.
ron;ević V PMID: 31530531 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Šaban J, Milošević V Tags: Turk J Gastroenterol Source Type: research

Endobiliary radiofrequency ablation and percutaneous biliary stent placement for choledocal invasion of renal cell carcinoma.
PMID: 31530532 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Ayaz E, Aşık M Tags: Turk J Gastroenterol Source Type: research

Laser treatment of congenital esophageal stenosis and web at the upper esophageal sphincter.
;akır Ö PMID: 31530533 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Özer Çakır Ö Tags: Turk J Gastroenterol Source Type: research

Post-colonoscopy colorectal cancer rates in the Swedish IBD and non-IBD population: Something missed or something faster?
stündağ Y PMID: 31530534 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - September 1, 2019 Category: Gastroenterology Authors: Yılmaz Ürün Y, Üstündağ Y Tags: Turk J Gastroenterol Source Type: research

Covering the Cover.
PMID: 31418409 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Kani HT Tags: Turk J Gastroenterol Source Type: research

Role of endoscopic interventions and electroincision in benign anastomotic strictures following colorectal surgery.
CONCLUSION: Balloon dilation can be performed safely as the primary treatment option, because of its easy access and noninvasive application. Electroincision is also a safe and effective endoscopic technique that can be preferred especially when the balloon dilation fails. PMID: 31418410 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Acar T, Aslan F, Acar N, Kamer E, Ünsal B, Hacıyanlı M Tags: Turk J Gastroenterol Source Type: research

Effects of pentasa-combined probiotics on the microflora structure and prognosis of patients with inflammatory bowel disease.
CONCLUSION: The combination of probiotics and pentasa can improve microflora composition in patients with IBD and reduce the level of inflammatory cytokines; therefore, it is worthy of further clinical validation. PMID: 31418411 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Fan H, Du J, Liu X, Zheng WW, Zhuang ZH, Wang CD, Gao R Tags: Turk J Gastroenterol Source Type: research

Fall of another myth for colon cancer: Duration of symptoms does not differ between right- or left-sided colon cancers.
CONCLUSION: Symptom duration is not associated with localization, nor is the tumor stage. Diagnosis of colorectal cancer at an earlier stage may be best achieved by screening of the population. PMID: 31418412 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Öztürk E, Kuzu MA, Öztuna D, Işık Ö, Canda AE, Balık E, Erkasap S, Yoldaş T, Akyol C, Demirbaş S, Özoğul B, Topçu Ö, Gedik E, Baca B, Ergüner İ, Asoğlu O, Erkek B, Yılmazlar T, Reis E, Gençosmanoğlu R, Konan A Tags: Turk J Gastroenterol Source Type: research

Paritaprevir, ritonavir, ombitasvir, and dasabuvir treatment in renal transplant patients with hepatitis C virus infection.
CONCLUSION: In this real-life experience, all of the 21 PrOD-treated RT recipients reached SVR12. Tac or Csa serum levels were maintained within the normal range with close monitoring. PrOD regime can be successfully and safely used in RT recipients with HCV infection with close follow-up. PMID: 31418413 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Danış N, Toz H, Ünal N, Yılmaz M, Turan İ, Günşar F, Karasu Z, Ersöz G, Özkahya M, Akarca US Tags: Turk J Gastroenterol Source Type: research

A model to predict early hepatic encephalopathy in patients undergoing transjugular intrahepatic portosystemic shunt.
CONCLUSION: The logistic regression model based on age, Child-Pugh classification, and fibrinogen for early post-TIPS HE can effectively predict the risk of early HE after TIPS. PMID: 31418414 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Li Y, He X, Pang H Tags: Turk J Gastroenterol Source Type: research

A significant upsurge of body mass index in patients with chronic hepatitis C successfully treated with direct-acting antiviral regimens.
CONCLUSION: Treatment of chronic HCV with DAAs was associated with increased body mass index. Further studies are needed to explore if this effect is secondary to treatment with DAAs or is an improvement in the liver function and lifestyle of treated patients. PMID: 31418415 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Kassas ME, Alboraie M, Naguib M, Omar H, Tahan AE, Moaz I, Abdellah M, Ezzat S, Wifi MN, Sherief AF, Eltabbakh M, Abdelsalam L, Eissa AH, Omran D Tags: Turk J Gastroenterol Source Type: research

Percutaneous transpapillary biliary stent placement for distal malignant biliary obstruction: Outcomes and survival analysis.
Abstract BACKGROUND/AIMS: For distal malignant biliary obstruction (MBO), a percutaneous metal stent is usually inserted by the transpapillary method. However, stent-related complications and recurrent biliary obstruction following transpapillary stent placement are concerns, and survival analysis of patients with distal MBO has rarely been done. MATERIALS AND METHODS: From January 2012 to March 2016, 104 patients underwent transpapillary uncovered metal stent placement for distal MBO at our institution. Clinical success, complications, recurrent biliary obstruction rates, and predictors of survival were anal...
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Zu QQ, Zhang JX, Wang B, Ye W, Liu S, Shi HB Tags: Turk J Gastroenterol Source Type: research

Claudin-9 enhances the metastatic potential of hepatocytes via Tyk2/Stat3 signaling.
CONCLUSION: As an HCC proto-oncogene, CLDN9 affected the Stat3 signaling pathway via Tyk2 and ultimately enhanced the metastatic ability of hepatocytes. PMID: 31418417 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Liu H, Wang M, Liang N, Guan L Tags: Turk J Gastroenterol Source Type: research

Potential effects of xylopic acid on acetic acid-induced ulcerative colitis in rats.
This study aimed to investigate the anti-colitic potential of XA. MATERIALS AND METHODS: We investigated the effect of XA on body weight, disease activity, inflammatory cell infiltration, and generation of reactive oxygen species. Rats were treated with XA or sulphasalazine, challenged intrarectally with acetic acid with macroscopic and microscopic findings made after eight days. RESULTS: Administration of XA to rats with colitis resulted in an increase in body weight with significant (p
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Osafo N, Obiri DD, Danquah KO, Essel LB, Antwi AO Tags: Turk J Gastroenterol Source Type: research

A bioactive product lipoxin A4 attenuates liver fibrosis in an experimental model by regulating immune response and modulating the expression of regeneration genes.
CONCLUSION: The anti-inflammatory effect of LXA4 maintains the regenerative capacity of liver during fibrosis in an experimental liver fibrosis model. LXA4 may be therapeutically beneficial in liver fibrosis. PMID: 31418419 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Kurtoğlu EL, Kayhan B, Gül M, Kayhan B, Akdoğan Kayhan M, Karaca ZM, Yeşilada E, Yılmaz S Tags: Turk J Gastroenterol Source Type: research

Bacterial infections in cirrhotic patients.
l;ekin AH PMID: 31418420 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - August 1, 2019 Category: Gastroenterology Authors: Ömerci Baş B, Çekin AH Tags: Turk J Gastroenterol Source Type: research

Covering the Cover.
PMID: 31290745 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - July 1, 2019 Category: Gastroenterology Authors: Yapalı S Tags: Turk J Gastroenterol Source Type: research

The effect of concomitant ankylosing spondylitis on long-term outcome of patients with inflammatory bowel disease.
ik AF Abstract BACKGROUND/AIMS: The aim of the present study was to compare the demographic features and long-term outcomes of patients with inflammatory bowel disease (IBD) with or without ankylosing spondylitis (AS). MATERIALS AND METHODS: Among 1640 IBD (Crohn's disease and ulcerative colitis), 76 patients with IBD+AS were identified. The study group consisted of 76 patients with IBD with synchronous AS. The control group consisted of patients with only IBD, and those were selected according to their registry sequence number being the previous and next case to the diseased case with IBD+AS. The primary end...
Source: The Turkish Journal of Gastroenterology - July 1, 2019 Category: Gastroenterology Authors: Atay K, Eyvazov H, Bozcan S, Eşkazan T, Demir N, Hatemi İ, Erzin Y, Çelik AF Tags: Turk J Gastroenterol Source Type: research

One-day versus four-day antibiotic treatment for acute right colonic uncomplicated diverticulitis: A randomized clinical trial.
Abstract BACKGROUND/AIMS: Currently, right colonic uncomplicated diverticulitis is typically treated with antibiotic therapy. However, the optimal duration of treatment is unknown. The aim of the present study was to compare the treatment failure rates between 1- and 4-day antibiotic treatment protocols. MATERIALS AND METHODS: A prospective randomized study in adults presenting with uncomplicated diverticulitis at the first episode from July 2011 to June 2014 was performed. Patients were randomized to receive intravenous antibiotics for 1 day (1-day group) or intravenous and oral antibiotics for 4 days (4-day...
Source: The Turkish Journal of Gastroenterology - July 1, 2019 Category: Gastroenterology Authors: Park JH, Park HC, Lee BH Tags: Turk J Gastroenterol Source Type: research

Association of obesity with chronic kidney disease in elderly patients with nonalcoholic fatty liver disease.
CONCLUSION: Elderly obese patients with NAFLD are at a higher risk of CKD. NAFLD patients with advanced age, greater BMI, or higher serum uric acid levels are more prone to developing CKD. The renal function of NAFLD patients should be closely monitored. PMID: 31290748 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - July 1, 2019 Category: Gastroenterology Authors: Luo K, Bian J, Wang Q, Wang J, Chen F, Li H, Jin D Tags: Turk J Gastroenterol Source Type: research

Assessment of HLADP gene rs3128917 and rs9380343 polymorphisms in chronic HBV infection.
This study aims to assess the relationship of HLA gene variants to chronic HBV infection. MATERIALS AND METHODS: HLA variants were explored in 238 chronic HBV patients and in 238 individuals with spontaneous clearance of HBV using PCR-RFLP assay. RESULTS: The allele and genotype of rs9380343 polymorphism were associated with persistent HBV infection risk (allele: p=0.038, genotype: p=0.029), but rs3128917 polymorphism was not significant. Additionally, rs9380343 polymorphism was also related to increased risk of HBV infection in males (p
Source: The Turkish Journal of Gastroenterology - July 1, 2019 Category: Gastroenterology Authors: Akgöllü E Tags: Turk J Gastroenterol Source Type: research

The relationship between fibrosis and nodule structure and esophageal varices.
CONCLUSION: Although thrombocytopenia and splenomegaly may predict the presence of large esophageal varices, cirrhosis histopathology is the main factor in the presence of varices. PMID: 31290750 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - July 1, 2019 Category: Gastroenterology Authors: Coşar AM, Yakar T, Serin E, Özer B, Kayaselçuk F Tags: Turk J Gastroenterol Source Type: research

Newly-developed colonoscope (PCF-PQ260L) is useful for patients with difficult colons.
Abstract BACKGROUND/AIMS: Preforming total colonoscopy (TCS) is sometimes difficult due to adhesions or long colons. The PCF-PQ260L (PQL) was developed to overcome TCS-related difficulties. The aim of this study was to investigate the performance and usefulness of PQL for difficult colon cases. MATERIALS AND METHODS: This was a retrospective single center observational cohort study investigating differences in patient characteristics and examination performance between patients examined with PQL, versus standard (SD), scopes. Secondly, we directly compared PQL and SD scopes in patients treated with both types...
Source: The Turkish Journal of Gastroenterology - July 1, 2019 Category: Gastroenterology Authors: Inoki K, Yamada M, Kuwabara H, Takamaru H, Sekiguchi M, Sakamoto T, Matsuda T, Saito Y Tags: Turk J Gastroenterol Source Type: research