Association of Metabolic Dysfunction-Associated Fatty Liver Disease with Cognitive Impairment and All-Cause Dementia: A Comprehensive Review
Turk J Gastroenterol. 2024 Feb;35(2):76-82. doi: 10.5152/tjg.2024.23629.ABSTRACTMetabolic dysfunction-associated fatty liver disease (MAFLD) is a significant public health concern, affecting one-third of the global population and posing a risk for progressive liver disease. MAFLD is characterized by hepatic steatosis and impaired metabolic status, which not only impact the liver but also other systems of the human body, making it a multisystemic disorder. Emerging evidence suggests that MAFLD and its associated pathological pathways may contribute to cognitive impairment, potentially through neuroinflammation and neurodege...
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Eda Kaya Yusuf Y ılmaz Source Type: research

Acupuncture Versus Biofeedback for Treatment of Functional Anorectal Pain
CONCLUSION: Both acupuncture and biofeedback therapy reduced the pain of patients with functional anorectal pain. Biofeedback provided more relief in patients with pelvic floor dyssynergia, and acupuncture provided greater improvements in mental health status.PMID:38454239 | PMC:PMC10895862 | DOI:10.5152/tjg.2024.22516 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Yahong Xue Shuqing Ding Huifen Zhou Min Li Jianbao Cao Qian Chen Yijiang Ding Source Type: research

Investigation of Clinical, Laboratory, Imaging Findings and Histopathological Features of Patients w ıth Gastric Neuroendocrine Cell Hyperplasia
CONCLUSION: Neuroendocrine tumor development rate was found to be 4.3% in the background of neuroendocrine cell hyperplasia. Two factors predicting progression from neuroendocrine cell hyperplasia to neuroendocrine tumor can be elaborated as the presence of polypoid appearance due to neuroendocrine cell hyperplasia as confirmed via endoscopy and dysplasia as confirmed via histopathological examination.PMID:38454240 | PMC:PMC10895882 | DOI:10.5152/tjg.2024.22681 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Burcu Çoban G öksel Bengi G özde Derviş Hakim Şadiye Mehtat Ünlü Dudu Solako ğlu Kahraman Funda Barl ık Gamze Çapa Kaya M üjde Soytürk Source Type: research

Nine-Gene Prognostic Signature Related to Gut Microflora for Predicting the Survival in Gastric Cancer Patients
CONCLUSIONS: These results indicate the 9 differentially expressed genes related to gut microflora might predict the survival time of patients with gastric cancer. Both risk signature and nomogram could effectively predict the prognosis for patients with gastric cancer.PMID:38454241 | PMC:PMC10895821 | DOI:10.5152/tjg.2024.23063 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Qing Yue Wei Han Zi Ling Lu Source Type: research

Being a Female Gastroenterologist in Turkey
CONCLUSION: More effort is needed to keep a fair gender balance in Turkish gastroenterology society and to increase the women's representation in therapeutic endoscopy options and also in leadership positions.PMID:38454242 | PMC:PMC10895884 | DOI:10.5152/tjg.2024.22612 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Z üleyha Akhan Çetinkaya Özdal Ersoy Nurdan T özün Source Type: research

Efficacy and Safety of Peroral Endoscopic Myotomy in the Treatment of Zenker's Diverticulum: A Single-Center Experience
CONCLUSION: Zenker's peroral endoscopic myotomy is a successful and reliable method in the treatment of ZD, with low recurrence rates.PMID:38454243 | PMC:PMC10895880 | DOI:10.5152/tjg.2024.23402 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Abdullah Murat Buyruk Çağdaş Erdoğan Source Type: research

A Plasma Exosomal Metabolic Profiling of Nonalcoholic Fatty Liver Disease Patients Complicated with Impaired Fasting Glucose
CONCLUSION: Metabolomic analysis of plasma exosomes revealed a distinct change in fatty acids and related pathways in nonalcoholic fatty liver disease patients with impaired fasting glucose. These preliminary results provide a metabolomic snapshot and basis for further investigation of exosome biology for these patients.PMID:38454244 | PMC:PMC10895878 | DOI:10.5152/tjg.2024.22739 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Weiyun Jiang Qiaofei Jin Chunqing Li Yunhao Xun Source Type: research

Can Endothelin-1 Levels in Patients with Esophageal Variceal Bleeding at Admission Predict Rebleeding Within 5 Days?
CONCLUSION: Serum endothelin-1 levels appear to be a reliable, practical, noninvasive predictor of early variceal rebleeding and related comorbidities such as the severity of kidney affection and duration of hospital stay.PMID:38454245 | PMC:PMC10895874 | DOI:10.5152/tjg.2024.23028 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Shaker Wagih Shaltout A E Messery Ahmed Elshabrawi Ahmed I Amin Mostafa H Elshennawy Metwaly Ibrahim Mortada Walid ElSherbiny Hatem Elalfy Dina Elhammady Source Type: research

Microvascular Invasion in Hepatocellular Carcinoma: Some Puzzling Facets
CONCLUSION: For patients beyond Milan criteria, but not within Milan criteria, microvascular invasion plays a significant role in predicting recurrence and shorter survival after liver transplantation.PMID:38454246 | PMC:PMC10895888 | DOI:10.5152/tjg.2024.22769 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: İbrahim Umar Garzali Brian I Carr Volkan Ince Burak I şık Ay şe Nur Akatlı Sezai Y ılmaz Source Type: research

The Supression of Migration and Metastasis via Inhibition of Vascular Endothelial Growth Factor in Pancreatic Adenocarcinoma Cells Applied Danusertib
CONCLUSION: Danusertib, a pan-Aurora kinase inhibitor, is predicted to be used as a potential agent in pancreatic cancers due to its antitumor and anti-metastatic effect.PMID:38454247 | PMC:PMC10895890 | DOI:10.5152/tjg.2024.22319 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Erkan Alaba ş Ahmet Ata Özçimen Source Type: research

What Is the Optimal Treatment for Liver Hydatid Cysts in Emergency and Elective Situations?
Turk J Gastroenterol. 2024 Feb;35(2):158-159. doi: 10.5152/tjg.2024.23523.NO ABSTRACTPMID:38454248 | PMC:PMC10895872 | DOI:10.5152/tjg.2024.23523 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Enver Zerem Željko Puljiz Boris Zdilar Suad Kunosi ć Admir Kurtcehajic Omar Zerem Source Type: research

RE: What Is the Optimal Treatment for Liver Hydatid Cysts in Emergency and Elective Situations?
Turk J Gastroenterol. 2024 Feb;35(2):160. doi: 10.5152/tjg.2024.235342.NO ABSTRACTPMID:38454249 | PMC:PMC10895873 | DOI:10.5152/tjg.2024.235342 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Serdar Öter Metin Yal çın Source Type: research

Can Serum Histone H4 Level Be a Biomarker in Ulcerative Colitis?
CONCLUSION: Decreased serum histone H4 values may be used as an auxiliary marker in the progression and diagnosis of ulcerative colitis. Further studies are needed to delineate this relationship between clinical and laboratory traits of ulcerative colitis and serum histone H4.PMID:38454272 | PMC:PMC10837591 | DOI:10.5152/tjg.2024.22385 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: İrfan Küçük Fatih Özçelik Yusuf Yazgan İsmail Yılmaz Mustafa Kaplan İdris Yıldırım Source Type: research

Endoscopic Characteristics of Early Gastroesophageal Junction Adenocarcinomas and Assessment for Invasion Depth: A Case Series Study
CONCLUSION: The posterior side and lesser curvature of the GEJ are the high-incidence sites of GEJ adenocarcinoma. Both forward and backward views during endoscopy should be combined to detect the lesion. Endoscopic characteristics such as Is or IIc morphology, larger size, red color with subsquamous extension, and disordered microsurface with local fusion may indicate a higher pathological grade and deeper invasion.PMID:38454273 | PMC:PMC10837581 | DOI:10.5152/tjg.2024.23312 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Shunzhe Song Feng Yan Jingwen Zhang Aixia Gong Source Type: research

Results of Nucleos(t)ide Analog Treatment Discontinuation in Hepatitis B e-Antigen-Negative Chronic Hepatitis B: NUCSTOP Study
CONCLUSION: Despite receiving NAs suppression therapy for a long time, HBsAg loss occurs rarely. Although it was not life-threatening, most patients experienced relapses and treatment should be restarted. In our study, whether it is a coincidence that all patients with HBsAg loss are patients in whom NAs are used sequentially due to lamivudine resistance is an issue that needs to be further investigated.PMID:38454274 | PMC:PMC10837598 | DOI:10.5152/tjg.2024.23463 (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - March 7, 2024 Category: Gastroenterology Authors: Sercan Kiremit çi Koray Ko çhan G ülseren Seven Elmas Biberci Keskin G ülay Okay Yasemin Akkoyunlu Meliha Meri ç Koç Bilge S ümbül Hakan Şentürk Source Type: research