Advanced in Vitro Safety Assessment of Herbal Medicines for the Treatment of Non-Psychotic Mental Disorders in Pregnancy
This study suggests that extracts from St. John’s wort, California poppy, valerian, lavender, and hops are likely to be safe during pregnancy. High plasma concentrations of some relevant compounds—hyperforin and hypericin from St. John’s wort and valtrate from valerian—deserve special attention, however. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - June 23, 2022 Category: Drugs & Pharmacology Source Type: research

Integrated Quality by Design Approach for Quantification and Standardization of BetaSitosterol and Lupeol in a emCissus quadrangularisem Linn Plant Extracts and its Marketed Formulation by Reverse Phase High Performance Liquid Chromatography
Ashita Valerian D ’souza, Prajakta Patil, S. Khan and C. J. Puralae* (Source: Indian Journal of Pharmaceutical Sciences)
Source: Indian Journal of Pharmaceutical Sciences - June 18, 2022 Category: Drugs & Pharmacology Source Type: research

Clinical evidence for effectiveness of herbal medicines in treatment of obsessive- compulsive disorder, a review study
CONCLUSION: Overall, herbal medicines can be used as stand-alone therapies for OCD or in conjunction with other methods.PMID:35713134 | DOI:10.2174/1570163819666220616122543 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 17, 2022 Category: Drugs & Pharmacology Authors: Maryam Hosseini Abrishami Mohamad Reza Noras Atefeh Soltanifar Roshanak Salari Lida Jarahi Hamideh Khorram Pazhouh Source Type: research

Clinical evidence for effectiveness of herbal medicines in treatment of obsessive- compulsive disorder, a review study
CONCLUSION: Overall, herbal medicines can be used as stand-alone therapies for OCD or in conjunction with other methods.PMID:35713134 | DOI:10.2174/1570163819666220616122543 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 17, 2022 Category: Drugs & Pharmacology Authors: Maryam Hosseini Abrishami Mohamad Reza Noras Atefeh Soltanifar Roshanak Salari Lida Jarahi Hamideh Khorram Pazhouh Source Type: research

Clinical evidence for effectiveness of herbal medicines in treatment of obsessive- compulsive disorder, a review study
CONCLUSION: Overall, herbal medicines can be used as stand-alone therapies for OCD or in conjunction with other methods.PMID:35713134 | DOI:10.2174/1570163819666220616122543 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 17, 2022 Category: Drugs & Pharmacology Authors: Maryam Hosseini Abrishami Mohamad Reza Noras Atefeh Soltanifar Roshanak Salari Lida Jarahi Hamideh Khorram Pazhouh Source Type: research

Clinical evidence for effectiveness of herbal medicines in treatment of obsessive- compulsive disorder, a review study
CONCLUSION: Overall, herbal medicines can be used as stand-alone therapies for OCD or in conjunction with other methods.PMID:35713134 | DOI:10.2174/1570163819666220616122543 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 17, 2022 Category: Drugs & Pharmacology Authors: Maryam Hosseini Abrishami Mohamad Reza Noras Atefeh Soltanifar Roshanak Salari Lida Jarahi Hamideh Khorram Pazhouh Source Type: research

Clinical evidence for effectiveness of herbal medicines in treatment of obsessive- compulsive disorder, a review study
CONCLUSION: Overall, herbal medicines can be used as stand-alone therapies for OCD or in conjunction with other methods.PMID:35713134 | DOI:10.2174/1570163819666220616122543 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 17, 2022 Category: Drugs & Pharmacology Authors: Maryam Hosseini Abrishami Mohamad Reza Noras Atefeh Soltanifar Roshanak Salari Lida Jarahi Hamideh Khorram Pazhouh Source Type: research

Clinical evidence for effectiveness of herbal medicines in treatment of obsessive- compulsive disorder, a review study
CONCLUSION: Overall, herbal medicines can be used as stand-alone therapies for OCD or in conjunction with other methods.PMID:35713134 | DOI:10.2174/1570163819666220616122543 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 17, 2022 Category: Drugs & Pharmacology Authors: Maryam Hosseini Abrishami Mohamad Reza Noras Atefeh Soltanifar Roshanak Salari Lida Jarahi Hamideh Khorram Pazhouh Source Type: research

Protective effect of valerian extract capsule (VEC) on ethanol- and indomethacin-induced gastric mucosa injury and ameliorative effect of VEC on gastrointestinal motility disorder
CONCLUSIONS: VEC showed a potential gastroprotective effect, suggesting that VEC is a promising phytomedicine for the treatment of GI diseases.PMID:35658820 | DOI:10.1080/13880209.2022.2071449 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - June 6, 2022 Category: Drugs & Pharmacology Authors: Yuan Feng Wan Dai Junyu Ke Yong Cui Shuang Li Jingjing Ma Wenfeng Guo Gang Chen Ning Li Yanwu Li Source Type: research

Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae
CONCLUSIONS: An S. cerevisiae strain was constructed and optimized to produce VA, but the valerena-4,7(11)-diene oxidation by LsGAO2 is still the rate-limiting step for VA synthesis that needs to be further optimized in future studies.PMID:35643816 | DOI:10.1007/s10529-022-03264-9 (Source: Biotechnology Letters)
Source: Biotechnology Letters - June 1, 2022 Category: Biotechnology Authors: Mengya Zhao Chuanbo Zhang Haibin Wang Shifan He Wenyu Lu Source Type: research

Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae
CONCLUSIONS: An S. cerevisiae strain was constructed and optimized to produce VA, but the valerena-4,7(11)-diene oxidation by LsGAO2 is still the rate-limiting step for VA synthesis that needs to be further optimized in future studies.PMID:35643816 | DOI:10.1007/s10529-022-03264-9 (Source: Biotechnology Letters)
Source: Biotechnology Letters - June 1, 2022 Category: Biotechnology Authors: Mengya Zhao Chuanbo Zhang Haibin Wang Shifan He Wenyu Lu Source Type: research

Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae
CONCLUSIONS: An S. cerevisiae strain was constructed and optimized to produce VA, but the valerena-4,7(11)-diene oxidation by LsGAO2 is still the rate-limiting step for VA synthesis that needs to be further optimized in future studies.PMID:35643816 | DOI:10.1007/s10529-022-03264-9 (Source: Biotechnology Letters)
Source: Biotechnology Letters - June 1, 2022 Category: Biotechnology Authors: Mengya Zhao Chuanbo Zhang Haibin Wang Shifan He Wenyu Lu Source Type: research

Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae
CONCLUSIONS: An S. cerevisiae strain was constructed and optimized to produce VA, but the valerena-4,7(11)-diene oxidation by LsGAO2 is still the rate-limiting step for VA synthesis that needs to be further optimized in future studies.PMID:35643816 | DOI:10.1007/s10529-022-03264-9 (Source: Biotechnology Letters)
Source: Biotechnology Letters - June 1, 2022 Category: Biotechnology Authors: Mengya Zhao Chuanbo Zhang Haibin Wang Shifan He Wenyu Lu Source Type: research

Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae
CONCLUSIONS: An S. cerevisiae strain was constructed and optimized to produce VA, but the valerena-4,7(11)-diene oxidation by LsGAO2 is still the rate-limiting step for VA synthesis that needs to be further optimized in future studies.PMID:35643816 | DOI:10.1007/s10529-022-03264-9 (Source: Biotechnology Letters)
Source: Biotechnology Letters - June 1, 2022 Category: Biotechnology Authors: Mengya Zhao Chuanbo Zhang Haibin Wang Shifan He Wenyu Lu Source Type: research