Willingness to Engage in Collective Action After the Police Killing of an Unarmed Black Man: Differential Pathways for Black and White Individuals
Am J Community Psychol. 2022 Feb 15. doi: 10.1002/ajcp.12587. Online ahead of print.ABSTRACTThis cross-sectional survey study examined the underlying psychosocial constructs of Black (n = 163) and White (n = 246) university students' willingness to endorse racially motivated collective action. Consistent with the defensive motivation system model, we expected the police shooting of an unarmed Black American to activate concerns about personal safety, thereby eliciting negative affect, lack of forgiveness of the perpetrator, and motivation to engage in collective action. This path model was expected for both Black and White...
Source: American Journal of Community Psychology - February 15, 2022 Category: Psychiatry Authors: Brynn E Sheehan Valerian J Derlega Ralitsa S Maduro Delaram A Totonchi Source Type: research

Willingness to Engage in Collective Action After the Police Killing of an Unarmed Black Man: Differential Pathways for Black and White Individuals
Am J Community Psychol. 2022 Feb 15. doi: 10.1002/ajcp.12587. Online ahead of print.ABSTRACTThis cross-sectional survey study examined the underlying psychosocial constructs of Black (n = 163) and White (n = 246) university students' willingness to endorse racially motivated collective action. Consistent with the defensive motivation system model, we expected the police shooting of an unarmed Black American to activate concerns about personal safety, thereby eliciting negative affect, lack of forgiveness of the perpetrator, and motivation to engage in collective action. This path model was expected for both Black and White...
Source: American Journal of Community Psychology - February 15, 2022 Category: Psychiatry & Psychology Authors: Brynn E Sheehan Valerian J Derlega Ralitsa S Maduro Delaram A Totonchi Source Type: research

Willingness to Engage in Collective Action After the Police Killing of an Unarmed Black Man: Differential Pathways for Black and White Individuals
Am J Community Psychol. 2022 Feb 15. doi: 10.1002/ajcp.12587. Online ahead of print.ABSTRACTThis cross-sectional survey study examined the underlying psychosocial constructs of Black (n = 163) and White (n = 246) university students' willingness to endorse racially motivated collective action. Consistent with the defensive motivation system model, we expected the police shooting of an unarmed Black American to activate concerns about personal safety, thereby eliciting negative affect, lack of forgiveness of the perpetrator, and motivation to engage in collective action. This path model was expected for both Black and White...
Source: American Journal of Community Psychology - February 15, 2022 Category: Psychiatry Authors: Brynn E Sheehan Valerian J Derlega Ralitsa S Maduro Delaram A Totonchi Source Type: research

Alzheimer's disease and sleep disorders: Insights into the possible disease connections and the potential therapeutic targets
Asian J Psychiatr. 2021 Dec 2;68:102961. doi: 10.1016/j.ajp.2021.102961. Online ahead of print.ABSTRACTOne of the comorbid conditions in an individual with Alzheimer's disease is a sleep disorder. Clinical features of sleep disorders involve various sleep disturbances such as Obstructive Sleep Apnea (OSAS), Excessive Daytime Sleepiness (EDS), Rapid Eye Movement (REM), Breathing Disorders, Periodic limb movements in sleep (PLMS), etc. The primary tools used for the identification of such disturbances are Polysomnography (PSG) and Wrist actigraphy. This review will highlight and explains the different approaches used in the ...
Source: Asian Journal of Psychiatry - December 10, 2021 Category: Psychiatry Authors: Vaibhav S Marde Utkarsha A Atkare Shweta V Gawali Prerna L Tiwari Saurabh P Badole Nitu L Wankhede Brijesh G Taksande Aman B Upaganlawar Milind J Umekar Mayur B Kale Source Type: research

Molecules, Vol. 26, Pages 7421: Herbal Products Used in Menopause and for Gynecological Disorders
OEMONOM Herbal products are often used as an alternative to pharmacological therapy. Menopausal symptoms and gynecological disorders (such as premenstrual syndrome and dysmenorrhea) are the indications where pharmacological therapy may have serious adverse events, hence many women prefer to use herbal products to help with these symptoms. Here, we reviewed plants and derived products, which are commonly used for the abovementioned indications, focusing on clinical data, safely profile and whether or not their use is justified. We noted that limited data are available on the use of some plants for alleviating the sympto...
Source: Molecules - December 8, 2021 Category: Chemistry Authors: Ma ša Kenda Nina Ko čevar Glavač Milan Nagy Marija Sollner Dolenc on behalf of the OEMONOM Tags: Review Source Type: research

4D Structural root architecture modeling from digital twins by X-Ray Computed Tomography
Breakthrough imaging technologies may challenge the plant phenotyping bottleneck regarding marker-assisted breeding and genetic mapping. In this context, X-Ray CT (computed tomography) technology can accuratel... (Source: Plant Methods)
Source: Plant Methods - December 4, 2021 Category: Biology Authors: Monica Herrero-Huerta, Valerian Meline, Anjali S. Iyer-Pascuzzi, Augusto M. Souza, Mitchell R. Tuinstra and Yang Yang Tags: Research Source Type: research

15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type-2 inflammation
J Clin Invest. 2021 Nov 11:e151685. doi: 10.1172/JCI151685. Online ahead of print.ABSTRACTAltered redox biology challenges all cells, with compensatory responses often determining a cell's fate. When 15 lipoxygenase-1 (15LO1), a lipid peroxidizing enzyme abundant in asthmatic human airway epithelial cells (HAECs), binds phosphatidylethanolamine binding protein-1 (PEBP1), hydroperoxy-phospholipids, which drive ferroptotic cell death, are generated. Peroxidases, including glutathione peroxidase-4 (GPX4), metabolize hydroperoxy-phospholipids to hydroxy derivatives to prevent ferroptotic death, but consume reduced glutathione ...
Source: Clinical Lung Cancer - November 11, 2021 Category: Cancer & Oncology Authors: Tadao Nagasaki Alexander J Schuyler Jinming Zhao Svetlana N Samovich Kazuhiro Yamada Yanhan Deng Scott P Ginebaugh Stephanie A Christenson Prescott G Woodruff John V Fahy John B Trudeau Detcho Stoyanovsky Anuradha Ray Yulia Y Tyurina Valerian E Kagan Sall Source Type: research

15LO1 dictates glutathione redox changes in asthmatic airway epithelium to worsen type-2 inflammation
J Clin Invest. 2021 Nov 11:e151685. doi: 10.1172/JCI151685. Online ahead of print.ABSTRACTAltered redox biology challenges all cells, with compensatory responses often determining a cell's fate. When 15 lipoxygenase-1 (15LO1), a lipid peroxidizing enzyme abundant in asthmatic human airway epithelial cells (HAECs), binds phosphatidylethanolamine binding protein-1 (PEBP1), hydroperoxy-phospholipids, which drive ferroptotic cell death, are generated. Peroxidases, including glutathione peroxidase-4 (GPX4), metabolize hydroperoxy-phospholipids to hydroxy derivatives to prevent ferroptotic death, but consume reduced glutathione ...
Source: Clinical Lung Cancer - November 11, 2021 Category: Cancer & Oncology Authors: Tadao Nagasaki Alexander J Schuyler Jinming Zhao Svetlana N Samovich Kazuhiro Yamada Yanhan Deng Scott P Ginebaugh Stephanie A Christenson Prescott G Woodruff John V Fahy John B Trudeau Detcho Stoyanovsky Anuradha Ray Yulia Y Tyurina Valerian E Kagan Sall Source Type: research

New Ln-MOFs based on mixed organic ligands: synthesis, structure and efficient luminescence sensing of the Hg2+ ions in aqueous solutions
Dalton Trans., 2021,50,15612-15619 DOI: 10.1039/D1DT02687A, PaperShu-Ju Wang, Qian Li, Guan-Lin Xiu, Li-Xin You, Fu Ding, Rik Van Deun, Ileana Dragutan, Valerian Dragutan, Ya-Guang Sun Four Ln-MOFs (Ln = Ce, Pr, Eu and Tb) based on thiobis(4-methylene-benzoic acid) and 1,10-phenanthroline were synthesized. The Eu-MOF selectively acts as an excellent luminescence probe for the detection of Hg2+ ions in waters. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Dalton Trans. latest articles)
Source: RSC - Dalton Trans. latest articles - November 11, 2021 Category: Chemistry Authors: Shu-Ju Wang Source Type: research

Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: pathologic, physiologic and detailed molecular profiling
Transl Res. 2021 Nov 2:S1931-5244(21)00263-2. doi: 10.1016/j.trsl.2021.10.007. Online ahead of print.ABSTRACTThe acute respiratory distress syndrome (ARDS) is a common complication of severe COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. Knowledge of molecular mechanisms driving host responses to SARS-CoV-2 is limited by the lack of reliable preclinical models of COVID-19 that recapitulate human illness. Further, existing COVID-19 animal models are not characterized as models of experimental acute lung injury (ALI) or ARDS. Acknowledging differences in ...
Source: Translational Research : the journal of laboratory and clinical medicine - November 6, 2021 Category: Laboratory Medicine Authors: Joseph S Bednash Valerian E Kagan Joshua A Englert Daniela Farkas Yulia Y Tyurina Vladimir A Tyurin Svetlana N Samovich Laszlo Farkas Ajit Elhance Finny Johns Hyunwook Lee Lijun Cheng Abhishek Majumdar Daniel Jones Oscar Rosas Mejia Marisa Ruane-Foster Ja Source Type: research

Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: pathologic, physiologic and detailed molecular profiling
Transl Res. 2021 Nov 2:S1931-5244(21)00263-2. doi: 10.1016/j.trsl.2021.10.007. Online ahead of print.ABSTRACTThe acute respiratory distress syndrome (ARDS) is a common complication of severe COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. Knowledge of molecular mechanisms driving host responses to SARS-CoV-2 is limited by the lack of reliable preclinical models of COVID-19 that recapitulate human illness. Further, existing COVID-19 animal models are not characterized as models of experimental acute lung injury (ALI) or ARDS. Acknowledging differences in ...
Source: Translational Research : the journal of laboratory and clinical medicine - November 6, 2021 Category: Laboratory Medicine Authors: Joseph S Bednash Valerian E Kagan Joshua A Englert Daniela Farkas Yulia Y Tyurina Vladimir A Tyurin Svetlana N Samovich Laszlo Farkas Ajit Elhance Finny Johns Hyunwook Lee Lijun Cheng Abhishek Majumdar Daniel Jones Oscar Rosas Mejia Marisa Ruane-Foster Ja Source Type: research

Dietary supplements, cytochrome metabolism, and pharmacogenetic considerations
ConclusionCYP P450 activity is an important consideration for any patient but becomes increasingly critical if patients have certain CYP P450 phenotypes that impact metabolism. These popular supplements have the potential for changes in supplement exposure, and adverse effects based on pharmacogenetic profiles. Furthermore, these sites of metabolism are shared with many medications, setting the stage for possibly more profound interactions between medications and supplements. This paper highlights the mechanisms in which dietary supplements may constitute a risk for patients with certain CYP P450 phenotypes. Further resear...
Source: Irish Journal of Medical Science - November 4, 2021 Category: General Medicine Source Type: research

Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling
The acute respiratory distress syndrome (ARDS) is a common complication of severe COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. Knowledge of molecular mechanisms driving host responses to SARS-CoV-2 is limited by the lack of reliable preclinical models of COVID-19 that recapitulate human illness. Further, existing COVID-19 animal models are not characterized as models of experimental acute lung injury (ALI) or ARDS. Acknowledging differences in experimental lung injury in animal models and human ARDS, here we systematically evaluate a model of experime...
Source: Translational Research - November 2, 2021 Category: Research Authors: JOSEPH S. BEDNASH, VALERIAN E. KAGAN, JOSHUA A. ENGLERT, DANIELA FARKAS, YULIA Y. TYURINA, VLADIMIR A. TYURIN, SVETLANA N. SAMOVICH, LASZLO FARKAS, AJIT ELHANCE, FINNY JOHNS, HYUNWOOK LEE, LIJUN CHENG, ABHISHEK MAJUMDAR, DANIEL JONES, OSCAR ROSAS MEJIA, M Source Type: research

Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: pathologic, physiologic and detailed molecular profiling
The acute respiratory distress syndrome (ARDS) is a common complication of severe COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection. Knowledge of molecular mechanisms driving host responses to SARS-CoV-2 is limited by the lack of reliable preclinical models of COVID-19 that recapitulate human illness. Further, existing COVID-19 animal models are not characterized as models of experimental acute lung injury (ALI) or ARDS. Acknowledging differences in experimental lung injury in animal models and human ARDS, here we systematically evaluate a model of experime...
Source: Translational Research - November 2, 2021 Category: Research Authors: Joseph S. Bednash, Valerian E. Kagan, Joshua A. Englert, Daniela Farkas, Yulia Y. Tyurina, Vladimir A. Tyurin, Svetlana N. Samovich, Laszlo Farkas, Ajit Elhance, Finny Johns, Hyunwook Lee, Lijun Cheng, Abhishek Majumdar, Daniel Jones, Oscar Rosas Mejia, M Source Type: research