Synthesis of lipid-linked oligosaccharides by a compartmentalized multi-enzyme cascade for the in vitro N-glycosylation of peptides
Publication date: Available online 9 July 2020Source: Journal of BiotechnologyAuthor(s): Thomas F.T. Rexer, Lisa Wenzel, Marcus Hoffmann, Sebastian Tischlik, Christin Bergmann, Valerian Grote, Simon Boecker, Katja Bettenbrock, Anna Schildbach, Robert Kottler, Reza Mahour, Erdmann Rapp, Markus Pietzsch, Udo Reichl (Source: Journal of Biotechnology)
Source: Journal of Biotechnology - July 10, 2020 Category: Biotechnology Source Type: research

Identifying Herbal Adverse Events From Spontaneous Reporting Systems Using Taxonomic Name Resolution Approach.
This study aimed to extract, standardize, and summarize supplement-relevant reports from two SRSs: (1) Food and Drug Administration Adverse Event Reporting System (FAERS) and (2) Canada Vigilance Adverse Reaction (CVAR) database. A thesaurus of plant names was developed and integrated with a mapping and normalization approach that accommodated misspellings and variants. The reports gathered from FAERS between the years 2004 and 2016 show 185,915 herbal and 7,235,330 non-herbal accounting for 2.51%. The data from CVAR found 36,940 reports of herbal and 503,580 non-herbal reports between the years 1965 and 2017 for a total o...
Source: Bioinformatics and Biology Insights - July 1, 2020 Category: Bioinformatics Authors: Sharma V, Gelin LFF, Sarkar IN Tags: Bioinform Biol Insights Source Type: research

[ASAP] Effect of Topology and Molecular Properties on the Rheology and Fatigue Behavior of Solid Polystyrene/Polyisoprene Di- and Triblock Copolymers
MacromoleculesDOI: 10.1021/acs.macromol.0c00632 (Source: Macromolecules)
Source: Macromolecules - June 16, 2020 Category: Chemistry Authors: Valerian Hirschberg †‡, Lorenz Faust†, Denis Rodrigue‡, and Manfred Wilhelm*† Source Type: research

Popescu technique revisited: review of the literature and case series
Management of vascular malformations depends on size, type, age of the patient, location, dissemination and depth of penetration. Treatment options include propranolol, which reduces endothelial vessel proliferation, minimally invasive sclerotherapy to induce fibrosis, or surgery. In 1985 Valerian Popescu described a new approach to treatment consisting of intra-tumoral ligation by compartmentalization. This technique allows for high doses of the sclerosant agent to be delivered as systemic dissemination is restricted by a series of strangulating suture loops that divide the mass into segments. (Source: Journal of Oral and...
Source: Journal of Oral and Maxillofacial Surgery - May 24, 2020 Category: ENT & OMF Authors: Ashley Ferro, Ana Otero-Rico, Vijay Santhanam Tags: Case Report Source Type: research

Plant Extracts for Sleep Disturbances: A Systematic Review.
Conclusions: Sleep aids based on plant extracts are generally safe and well tolerated by the population. More high-quality research is needed to confirm the effectiveness of food supplements containing plant extracts in sleep complaints; in particular, it would be interesting to evaluate the association between plant extracts and sleep hygiene guidelines and to identify the optimal products to be used in a specific symptom of sleep complaint, giving more appropriate tools to the medical doctor. PMID: 32382286 [PubMed] (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - May 10, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research