Activation of Cytochrome C Peroxidase Function Through Coordinated Foldon Loop Dynamics upon Interaction with Anionic Lipids
Publication date: Available online 24 May 2021Source: Journal of Molecular BiologyAuthor(s): Mingyue Li, Wanyang Sun, Vladimir A. Tyurin, Maria DeLucia, Jinwoo Ahn, Valerian E. Kagan, Patrick C.A. van der Wel (Source: Journal of Molecular Biology)
Source: Journal of Molecular Biology - May 25, 2021 Category: Molecular Biology Source Type: research
Molecules, Vol. 26, Pages 3155: Back to the Roots —An Overview of the Chemical Composition and Bioactivity of Selected Root-Essential Oils
Molecules, Vol. 26, Pages 3155: Back to the Roots—An Overview of the Chemical Composition and Bioactivity of Selected Root-Essential Oils
Molecules doi: 10.3390/molecules26113155
Authors:
Karin Lunz
Iris Stappen
Since ancient times, plant roots have been widely used in traditional medicine for treating various ailments and diseases due to their beneficial effects. A large number of studies have demonstrated that—besides their aromatic properties—their biological activity can often be attributed to volatile constituents. This review provides a comprehensive overview of investigations into the chemical compos...
Source: Molecules - May 25, 2021 Category: Chemistry Authors: Karin Lunz Iris Stappen Tags: Review Source Type: research
Ni and Cr impurities profile in Valeriana officinalis L., radix-based herbal medicinal product available in Polish pharmacies due to ICH Q3D guideline
Regul Toxicol Pharmacol. 2021 May 12:104945. doi: 10.1016/j.yrtph.2021.104945. Online ahead of print.ABSTRACTElemental impurities (EIs) profiling in final pharmaceutical products is often not adequately treated, however it is crucial problem in pharmaceutical analysis by reason of the various regulatory authorities (like ICH Q3D guideline). EIs in pharmaceuticals may arise from numerous sources of which the herbal ingredients are not a frequent subject of pharmaceutical analyses. However, based on number of traditional use registrations per year for herbal medicinal products (HMPs) in the EU, it can be stated that monocomp...
Source: Regulatory Toxicology and Pharmacology : RTP - May 15, 2021 Category: Toxicology Authors: Kamil Jurowski Maria Fo łta Barbara Tatar Mehmet Berkoz Miros ław Krośniak Source Type: research
Ni and Cr impurities profile in Valeriana officinalis L., radix-based herbal medicinal product available in Polish pharmacies due to ICH Q3D guideline
Regul Toxicol Pharmacol. 2021 May 12:104945. doi: 10.1016/j.yrtph.2021.104945. Online ahead of print.ABSTRACTElemental impurities (EIs) profiling in final pharmaceutical products is often not adequately treated, however it is crucial problem in pharmaceutical analysis by reason of the various regulatory authorities (like ICH Q3D guideline). EIs in pharmaceuticals may arise from numerous sources of which the herbal ingredients are not a frequent subject of pharmaceutical analyses. However, based on number of traditional use registrations per year for herbal medicinal products (HMPs) in the EU, it can be stated that monocomp...
Source: Regulatory Toxicology and Pharmacology : RTP - May 15, 2021 Category: Toxicology Authors: Kamil Jurowski Maria Fo łta Barbara Tatar Mehmet Berkoz Miros ław Krośniak Source Type: research
Ni and Cr impurities profile in Valeriana officinalis L., radix-based herbal medicinal product available in Polish pharmacies due to ICH Q3D guideline
Regul Toxicol Pharmacol. 2021 May 12:104945. doi: 10.1016/j.yrtph.2021.104945. Online ahead of print.ABSTRACTElemental impurities (EIs) profiling in final pharmaceutical products is often not adequately treated, however it is crucial problem in pharmaceutical analysis by reason of the various regulatory authorities (like ICH Q3D guideline). EIs in pharmaceuticals may arise from numerous sources of which the herbal ingredients are not a frequent subject of pharmaceutical analyses. However, based on number of traditional use registrations per year for herbal medicinal products (HMPs) in the EU, it can be stated that monocomp...
Source: Regulatory Toxicology and Pharmacology : RTP - May 15, 2021 Category: Toxicology Authors: Kamil Jurowski Maria Fo łta Barbara Tatar Mehmet Berkoz Miros ław Krośniak Source Type: research
Ni and Cr impurities profile in Valeriana officinalis L., radix-based herbal medicinal product available in Polish pharmacies due to ICH Q3D guideline
Publication date: Available online 13 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Kamil Jurowski, Maria Fołta, Barbara Tatar, Mehmet Berkoz, Mirosław Krośniak (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 13, 2021 Category: Toxicology Source Type: research
Structural insights into new luminescent 2D lanthanide coordination polymers using an N, N’-disubstituted benzimidazole zwitterion. Influence of the ligand
Publication date: Available online 8 May 2021Source: Inorganica Chimica ActaAuthor(s): Li-Xin You, Sen-Yue Cao, Yang Guo, Shu-Ju Wang, Gang Xiong, Ileana Dragutan, Valerian Dragutan, Fu Ding, Ya-Guang Sun (Source: Inorganica Chimica Acta)
Source: Inorganica Chimica Acta - May 8, 2021 Category: Chemistry Source Type: research
Comparison of transversus abdominis plane catheters with thoracic epidurals for cost and length of stay in open colorectal surgeries: a cohort study
Thoracic epidural analgesia has long been a common method of postoperative analgesia for major open abdominal surgeries and is frequently used within enhanced recovery after surgery programs. An alternative po... (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - May 6, 2021 Category: Anesthesiology Authors: David Miller, Peter Andriakos, Justin VanBacker, Erin Macbeth, Igor Galay, Dilip Sidhu, Divya Cherukupalli, Edward Lee, Brian Valerian, A. David Chismark, Jonathan Canete and Farzana Afroze Tags: Research Source Type: research
8-hydroxypinoresinol-4-O-β-D-glucoside from Valeriana officinalis L. Is a Novel Kv1.5 Channel Blocker
Publication date: 10 August 2021Source: Journal of Ethnopharmacology, Volume 276Author(s): Xingxing Liu, Xueyun Duan, Heng Fan, Hongfei Wang, Xionggang Jiang, Ying Fang, Qing Tang, Jun Xiao, Qian Li (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - May 5, 2021 Category: Drugs & Pharmacology Source Type: research
The Effects of Valerian on Sleep Quality, Depression, and State Anxiety in Hemodialysis Patients: A Randomized, Double-blind, Crossover Clinical Trial
CONCLUSIONS: Valerian significantly improved sleep quality, the symptoms of state anxiety, and depression in HD patients.PMID:33936782 | PMC:PMC8077445 | DOI:10.5001/omj.2021.56 (Source: Oman Medical Journal)
Source: Oman Medical Journal - May 3, 2021 Category: Middle East Health Authors: Mohammad Reza Tammadon Monir Nobahar Zaynab Hydarinia-Naieni Abbasali Ebrahimian Raheb Ghorbani Abbas Ali Vafaei Source Type: research
Use of Plant-Derived Natural Products in Sleep Disturbances
Adv Exp Med Biol. 2021;1308:217-224. doi: 10.1007/978-3-030-64872-5_15.ABSTRACTSleep disorders have a high prevalence both in the general population and especially in specific populations such older adults and oncologic patients. Impacting on quality of life, they often translate in drug prescription, with consequent increased risk of drug-drug interactions and adverse drug reactions. In the last years several products derived from plants have been developed with the aim of treating insomnia with lower risk of side effects. Despite several studies have been performed with this aim, the available evidence is inconclusive, a...
Source: Advances in Experimental Medicine and Biology - April 16, 2021 Category: Research Authors: Diana Lelli Livio Cortese Claudio Pedone Source Type: research
