The Toxicological Risk Assessment of Lead and Cadmium in Valeriana officinalis L., radix (Valerian root) as Herbal Medicinal Product for the Relief of Mild Nervous Tension and Sleep Disorders Available in Polish Pharmacies
Biol Trace Elem Res. 2021 Apr 1. doi: 10.1007/s12011-021-02691-5. Online ahead of print.ABSTRACTStudies related to the toxicological risk assessment (TRA) of heavy metal impurities (HMIs) in pharmaceuticals are an important issue but there is a lack of refereed literature around the safety of Valeriana officinalis L., radix (Valerian root) as herbal medicinal product (HMP) for the relief of mild nervous tension and sleep disorders according to lead and cadmium impurities. The aim of the study was to estimate the TRA of lead and cadmium in Valeriana officinalis L., radix (Valerian root) as HMP (n = 5) available in Polish ph...
Source: Biological Trace Element Research - April 1, 2021 Category: Biology Authors: Kamil Jurowski Maria Fo łta Barbara Tatar Mehmet Berkoz Miros ław Krośniak Source Type: research
Molecules, Vol. 26, Pages 1992: Effect of Botanical Extracts on the Growth and Nutritional Quality of Field-Grown White Head Cabbage (Brassica oleracea var. capitata)
szula Piszcz
Nutraceuticals and functional foods are gaining more attention amongst consumers interested in nutritious food. The consumption of foodstuffs with a high content of phytochemicals has been proven to provide various health benefits. The application of biostimulants is a potential strategy to fortify cultivated plants with beneficial bioactive compounds. Nevertheless, it has not yet been established whether the proposed higher plants (St. John’s wort, giant goldenrod, common dandelion, red clover, nettle, and valerian) are appropriate for the production of potential bio-products enhancing the nutritional v...
Source: Molecules - April 1, 2021 Category: Chemistry Authors: Katarzyna Godlewska Pawe ł Pacyga Izabela Michalak Anita Biesiada Antoni Szumny Natalia Pachura Urszula Piszcz Tags: Article Source Type: research
Molecules, Vol. 26, Pages 1827: Increased Stress Resistance and Lifespan in Chaenorhabditis elegans Wildtype and Knockout Mutants —Implications for Depression Treatment by Medicinal Herbs
Molecules, Vol. 26, Pages 1827: Increased Stress Resistance and Lifespan in Chaenorhabditis elegans Wildtype and Knockout Mutants—Implications for Depression Treatment by Medicinal Herbs
Molecules doi: 10.3390/molecules26071827
Authors:
Janine Naß
Christopher J. Kampf
Thomas Efferth
Depression and anxiety disorders are widespread diseases, and they belong to the leading causes of disability and greatest burdens on healthcare systems worldwide. It is expected that the numbers will dramatically rise during the COVID-19 pandemic. Established medications are not sufficient to adequately treat depression and are ...
Source: Molecules - March 24, 2021 Category: Chemistry Authors: Janine Na ß Christopher J. Kampf Thomas Efferth Tags: Article Source Type: research
Electro-optic comb pumped optical parametric oscillator with flexible repetition rate at GHz level
We present a gigahertz (GHz)-repetition-rate optical parametric oscillator (OPO) pumped by an electro-optic comb at 1.03 µ m, ... (Source: Optics Letters)
Source: Optics Letters - March 23, 2021 Category: Physics Authors: Hanyu Ye Valerian Freysz Ramatou Bello-Doua Lilia Pontagnier Giorgio Santarelli Eric Cormier Eric Freysz Source Type: research
Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spec-trometry (GCIB-SIMS)
Angew Chem Int Ed Engl. 2021 Mar 8. doi: 10.1002/anie.202102001. Online ahead of print.ABSTRACTPeroxidized phosphatidylethanolamine (PEox) species have been identified by Liquid Chromatography Mass Spectrometry (LC-MS) as predictive biomarkers of ferroptosis, a new program of regulated cell death. However, the presence and subcellular distribution of PEox in specific cell types and tissues have not been directly detected by imaging protocols. By applying Gas Cluster Ion Beam Secondary Ion Mass Spectrometry (GCIB-SIMS) imaging with a 70 keV (H 2 O) n + (n>28,000) cluster ion beam, we were able to map PEox with 1.2 micron...
Source: Angewandte Chemie - March 8, 2021 Category: Chemistry Authors: Louis Sparvero Hua Tian Andrew A Amoscato Wan-Yang Sun Tamil S Anthonymuthu Yulia Y Tyurina Oleksandr Kapralov Sabzali Javadov Rong-Rong He Simon C Watkins Nicholas Winograd Valerian E Kagan H ülya Bayır Source Type: research
Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spec-trometry (GCIB-SIMS)
Angew Chem Int Ed Engl. 2021 Mar 8. doi: 10.1002/anie.202102001. Online ahead of print.ABSTRACTPeroxidized phosphatidylethanolamine (PEox) species have been identified by Liquid Chromatography Mass Spectrometry (LC-MS) as predictive biomarkers of ferroptosis, a new program of regulated cell death. However, the presence and subcellular distribution of PEox in specific cell types and tissues have not been directly detected by imaging protocols. By applying Gas Cluster Ion Beam Secondary Ion Mass Spectrometry (GCIB-SIMS) imaging with a 70 keV (H 2 O) n + (n>28,000) cluster ion beam, we were able to map PEox with 1.2 micron...
Source: Angewandte Chemie - March 8, 2021 Category: Chemistry Authors: Louis Sparvero Hua Tian Andrew A Amoscato Wan-Yang Sun Tamil S Anthonymuthu Yulia Y Tyurina Oleksandr Kapralov Sabzali Javadov Rong-Rong He Simon C Watkins Nicholas Winograd Valerian E Kagan H ülya Bayır Source Type: research
The healthy human virome: from virus–host symbiosis to disease
Publication date: April 2021Source: Current Opinion in Virology, Volume 47Author(s): Eugene V Koonin, Valerian V Dolja, Mart Krupovic (Source: Current Opinion in Virology)
Source: Current Opinion in Virology - March 1, 2021 Category: Virology Source Type: research
Identification of Valeriana fauriei and other Eurasian medicinal valerian by DNA polymorphisms in psb A – trn H intergenic spacer sequences in chloroplast DNA
AbstractIn order to differentiate amongValeriana fauriei Briq. and other Eurasian medicinal valerian (V.dioica L.,V.hardwickii Wall.,V.jatamansi Jones, andV.officinalis L.), we attempted to establish DNA markers. DNA sequences for thepsbA –trnH intergenic spacer region of chloroplast DNA (psbA –trnH) and 18S ribosomal RNA, internal transcribed spacer 1 (ITS1), 5.8S ribosomal RNA, internal transcribed spacer 2 (ITS2), and 28S ribosomal RNA of nuclear DNA inV. fauriei and other Eurasian medicinal valerian were compared. Using partial sequences ofpsbA –trnH (nucleotide positions 1 –75 from the 5′ end of the intergen...
Source: Journal of Natural Medicines - February 25, 2021 Category: Drugs & Pharmacology Source Type: research
Rapid emergence of virus-host mutualism under stress [Evolution]
Broad Spectrum of Outcomes in Virus–Host Interactions The article by González et al. (1) in PNAS illuminates the flexibility of the virus–host relationships by demonstrating a rapid shift to mutualism under stress in an RNA plant virus model. A common public perception of a virus, particularly relevant in the time... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - February 17, 2021 Category: Science Authors: Valerian V. Dolja Tags: Evolution, Commentaries Commentary Source Type: research
Urethrocutaneous fistulas after voluntary medical male circumcision for HIV prevention —15 African Countries, 2015–2019
Voluntary medical male circumcision (VMMC) is an HIV prevention strategy recommended to partially protect men from heterosexually acquired HIV. From 2015 to 2019, the President ’s Emergency Plan for AIDS Relief... (Source: BMC Urology)
Source: BMC Urology - February 12, 2021 Category: Urology & Nephrology Authors: Todd Lucas, Jonas Z. Hines, Julia Samuelson, Timothy Hargreave, Stephanie M. Davis, Ian Fellows, Amber Prainito, D. Heather Watts, Valerian Kiggundu, Anne G. Thomas, Onkemetse Conrad Ntsuape, Kunle Dare, Elijah Odoyo-June, Leonard Soo, Likabelo Toti-Mokot Tags: Research article Source Type: research
Shaker Anodyne: Teetotalers ’ Valerian Elixir
A religious group founded in England in the 1740s, the Shakers were organized in the United States by the 1780s and lived in communes from upstate New York and New England to urban Philadelphia and the Midwest. A uniquely celibate sect of Christian teetotalers, their ecstatic singing and dancing at worship had earned them the sobriquet of “Shaking Quakers,” or Shakers. Up through the 1890s, their North Enfield (bottom, “Nth Enfield / N.H. ”) community in New Hampshire compounded “Brown’s Pure Extract of English Valerian,” better known as “Shaker Anodyne” (top). The root of the English, not American, Valer...
Source: Anesthesiology - February 10, 2021 Category: Anesthesiology Source Type: research
