Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring
This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg-1·day-1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was eval...
Source: Braz J Med Biol Res - September 29, 2021 Category: Research Authors: D P Carvalho V M Peters A F Dias S C P L Dutra M O Guerra Source Type: research

Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring
This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg-1·day-1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was eval...
Source: Brazilian Journal of Medical and Biological Research - September 29, 2021 Category: Research Authors: D P Carvalho V M Peters A F Dias S C P L Dutra M O Guerra Source Type: research

Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring
This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg-1·day-1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was eval...
Source: Braz J Med Biol Res - September 29, 2021 Category: Research Authors: D P Carvalho V M Peters A F Dias S C P L Dutra M O Guerra Source Type: research

Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring
This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg-1·day-1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was eval...
Source: Brazilian Journal of Medical and Biological Research - September 29, 2021 Category: Research Authors: D P Carvalho V M Peters A F Dias S C P L Dutra M O Guerra Source Type: research

Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring
This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg-1·day-1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was eval...
Source: Braz J Med Biol Res - September 29, 2021 Category: Research Authors: D P Carvalho V M Peters A F Dias S C P L Dutra M O Guerra Source Type: research

Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring
This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg-1·day-1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was eval...
Source: Brazilian Journal of Medical and Biological Research - September 29, 2021 Category: Research Authors: D P Carvalho V M Peters A F Dias S C P L Dutra M O Guerra Source Type: research

Long-Term Survival After Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A 16-Year Experience
CONCLUSIONS: ASA appears to be a safe and effective treatment for symptomatic HOCM refractory to medical therapy with long-term survival comparable to a demographically similar United States population.PMID:34559674 (Source: The Journal of Invasive Cardiology)
Source: The Journal of Invasive Cardiology - September 24, 2021 Category: Cardiology Authors: Valerian Fernandes Ahmadreza Karimianpour Jeremy D Rier Shawn Shaji Billy J Mullinax Amy H Wahlquist Christopher D Nielsen Source Type: research

Long-Term Survival After Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A 16-Year Experience
CONCLUSIONS: ASA appears to be a safe and effective treatment for symptomatic HOCM refractory to medical therapy with long-term survival comparable to a demographically similar United States population.PMID:34559674 (Source: The Journal of Invasive Cardiology)
Source: The Journal of Invasive Cardiology - September 24, 2021 Category: Cardiology Authors: Valerian Fernandes Ahmadreza Karimianpour Jeremy D Rier Shawn Shaji Billy J Mullinax Amy H Wahlquist Christopher D Nielsen Source Type: research

Long-Term Survival After Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A 16-Year Experience
CONCLUSIONS: ASA appears to be a safe and effective treatment for symptomatic HOCM refractory to medical therapy with long-term survival comparable to a demographically similar United States population.PMID:34559674 (Source: The Journal of Invasive Cardiology)
Source: The Journal of Invasive Cardiology - September 24, 2021 Category: Cardiology Authors: Valerian Fernandes Ahmadreza Karimianpour Jeremy D Rier Shawn Shaji Billy J Mullinax Amy H Wahlquist Christopher D Nielsen Source Type: research

Herb-drug interactions in neuropsychiatric pharmacotherapy - a review of clinically relevant findings
This study reviewed the relevant literature and identified 13 commonly used herbal products - celery, echinacea, ginkgo, ginseng, hydroxycut, kava, kratom, moringa, piperine, rhodiola, St John's wort, terminalia/commiphora ayurvedic mixture and valerian - which have shown clinically relevant interactions with prescription drugs used in the management of neuropsychiatric disorders. The clinical focus is aimed to provide easily accessible information that will be of interest to clinicians, researchers, and the drug-consuming public.PMID:34370637 | DOI:10.2174/1570159X19666210809100357 (Source: Current Neuropharmacology)
Source: Current Neuropharmacology - August 9, 2021 Category: Drugs & Pharmacology Authors: Tram T Le Sarah R McGrath Pius S Fasinu Source Type: research