Brazilian Journal of Medical and Biological Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Combined effect of physical exercise and hormone replacement therapy on cardiovascular and metabolic health in postmenopausal women: A systematic review and meta-analysis
Braz J Med Biol Res. 2023 May 15;56:e12241. doi: 10.1590/1414-431X2023e12241. eCollection 2023.ABSTRACTThe cardioprotective effect of postmenopausal hormone replacement therapy (HRT) has been demonstrated in several studies. Similarly, physical exercise has yielded positive results. However, the effects of their combination remain inconclusive. This review describes the combined effects of physical exercise and hormone therapy on cardiovascular and metabolic health in postmenopausal women. We searched the Scopus, Web of Science, PubMed, and Embase databases and included randomized controlled trials published up to December...
Source: Brazilian Journal of Medical and Biological Research - May 17, 2023 Category: Research Authors: J C S ánchez-Delgado A M J ácome-Hortúa O M Uribe-Sarmiento S V Philbois A C Pereira K P Rodrigues H C D Souza Source Type: research

The myocardial capillary network is altered in congenital diaphragmatic hernia in the fetal rabbit model
Braz J Med Biol Res. 2023 May 15;56:e12521. doi: 10.1590/1414-431X2023e12521. eCollection 2023.ABSTRACTCongenital diaphragmatic hernia (CDH) is associated with thoracic compression of the lungs and heart caused by the herniated abdominal content, leading to cardiac modifications including pressure and vascular changes. Our aim was to investigate the experimental immunoexpression of the capillary proliferation, activation, and density of Ki-67, VEGFR2, and lectin in the myocardium after surgical creation of a diaphragmatic defect. Pregnant New Zealand rabbits were operated on the 25th gestational day in order to create left...
Source: Brazilian Journal of Medical and Biological Research - May 17, 2023 Category: Research Authors: A L A Nour A T Fabro S S Batah M Oria J L Peiro L Sbragia Source Type: research

Extraction and characterization of collagen from the skin of Amazonian freshwater fish pirarucu
In conclusion, the procedures used may be considered to be an interesting alternative for collagen extraction, a new product obtained from the processing of fish waste.PMID:37194834 | DOI:10.1590/1414-431X2023e12564 (Source: Brazilian Journal of Medical and Biological Research)
Source: Brazilian Journal of Medical and Biological Research - May 17, 2023 Category: Research Authors: K C R Carpio R S Bezerra T B Cah ú F T D do Monte R C A Neri J F da Silva P R Dos Santos R P Carvalho D M L Galeno A J Inhamuns Source Type: research

Anti-inflammatory, procollagen, and wound repair properties of topical insulin gel
This study aimed to investigate the therapeutic outcomes of insulin gel in wounds of hyperglycemic mice. After diabetes induction, a 1-cm2 full-thickness wound was created on each animal's dorsum. The lesions were treated daily for 14 days with insulin gel (insulin group) or vehicle gel without insulin (vehicle group). Tissue samples were extracted on days 4, 7, 10, and 14 after the creation of the lesion. The samples were analyzed with hematoxylin/eosin and Sirius red staining, immunohistochemistry, Bio-Plex immunoassays, and western blotting. Insulin gel favored re-epithelialization at day 10 and increased the organizati...
Source: Brazilian Journal of Medical and Biological Research - May 17, 2023 Category: Research Authors: P P Apolin ário F C Zanchetta J S C Breder G Adams S R Consonni R Gillis M J A Saad M H M Lima Source Type: research

Retraction notice for: "lncRNA ZEB1-AS1 inhibits high glucose-induced EMT and fibrogenesis by regulating the miR-216a-5p/BMP7 axis in diabetic nephropathy" [https://doi.org/10.1590/1414-431X20209288]
Braz J Med Biol Res. 2023 May 15;56:e9288retraction. doi: 10.1590/1414-431X2023e9288retraction.ABSTRACT[This retracts the article doi: 10.1590/1414-431X20209288].PMID:37194836 | DOI:10.1590/1414-431X2023e9288retraction (Source: Brazilian Journal of Medical and Biological Research)
Source: Brazilian Journal of Medical and Biological Research - May 17, 2023 Category: Research Source Type: research