Template-based peptide modeling for celiac risk assessment of newly expressed proteins in GM crops
Publication date: Available online 30 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Ping Song, Zhenglin Hou, Shravan Sukumar, Rod Herman (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 1, 2020 Category: Toxicology Source Type: research

A flow scheme for cumulative assessment of pesticides for adverse liver effects
Publication date: Available online 1 July 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Thomas Colnot, Stephanie Melching-Kollmuß, Giovanna Semino, Wolfgang Dekant (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 1, 2020 Category: Toxicology Source Type: research

Safety assessment of metarrestin in dogs: A clinical candidate targeting a subnuclear structure unique to metastatic cancer cells
Publication date: Available online 30 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Mohamed Bourdi, Udo Rudloff, Samarjit Patnaik, Juan Marugan, Pramod S. Terse (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - July 1, 2020 Category: Toxicology Source Type: research

Bolstering the existing database supporting the non-cancer Threshold of Toxicological Concern values with toxicity data on fragrance-related materials
Publication date: Available online 27 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Atish Patel, Kaushal Joshi, Jane Rose, Michael Laufersweiler, Susan P. Felter, Anne Marie Api (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 28, 2020 Category: Toxicology Source Type: research

Clinical epidemiology studies on potential effects of endocrine disrupting chemicals (EDCs) should exclude subjects with obesity as determined by BMI
Publication date: Available online 26 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Carr J. Smith, Thomas A. Perfetti, A. Wallace Hayes, Sir Colin Berry (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 27, 2020 Category: Toxicology Source Type: research

Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture
Publication date: Available online 23 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): James R. Turk, Aimee M. Deaton, Jun Yin, Marina Stolina, Melanie Felx, Gabrielle Boyd, Jean-Guy Bienvenu, Aurore Varela, Martin Guillot, Gill Holdsworth, Alison Wolfreys, Denise Dwyer, Sheetal V. Kumar, Emily M. de Koning, Yusheng Qu, Michael Engwall, Kathrin Locher, Lucas D. Ward, Charles Glaus, Yudong D. He (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 24, 2020 Category: Toxicology Source Type: research

Indicators for lack of systemic availability of organic pigments
Publication date: Available online 18 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Heidi Stratmann, Maria Hellmund, Ulrich Veith, Nicole End, Wera Teubner (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 19, 2020 Category: Toxicology Source Type: research

Corrigendum to “Assessment of the skin sensitisation hazard of functional polysiloxanes and silanes in the SENS-IS assay” [Regul. Toxicol. Pharmacol. 98 (2018) 209–214]
Publication date: Available online 19 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Thomas Petry, Axel Bosch, Farah Koraïchi-Emeriau, Dorothea Eigler, Pierre Germain, Shawn Seidel (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 19, 2020 Category: Toxicology Source Type: research

Replacing the refinement for skin sensitization testing: Considerations to the implementation of adverse outcome pathway (AOP)-based defined approaches (DA) in OECD guidelines
Publication date: Available online 17 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Susanne N. Kolle, Robert Landsiedel, Andreas Natsch (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 18, 2020 Category: Toxicology Source Type: research

Yellow-colored extract from cashew byproduct – Nonclinical safety assessment
Publication date: Available online 17 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Gisele Goulart da Silva, Adriana Della Torre, Lucia Elaine de Oliveira Braga, Patrícia Bachiega, Sirlene Valério Tinti, João Ernesto de Carvalho, Ana Paula Dionísio, Ana Lúcia Tasca Gois Ruiz (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 18, 2020 Category: Toxicology Source Type: research

Calculating safety margins using total plasma concentration versus unbound plasma concentration - Does it make a difference?
Publication date: Available online 15 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Suman K. Mukherjee, James B. Ferry (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 16, 2020 Category: Toxicology Source Type: research

Establishing health-based biological exposure limits for pesticides: A proof of principle study using mancozeb
Publication date: Available online 13 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Stefan Mandić-Rajčević, Federico Maria Rubino, Claudio Colosio (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 14, 2020 Category: Toxicology Source Type: research

Safety evaluation of E12, W8, X17, and Y9 potatoes: Nutritional evaluation and 90-day subchronic feeding study in rats
Publication date: Available online 12 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Pushkor Mukerji, Gary W. Rudgers, Christopher Gibson, Jason M. Roper (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 13, 2020 Category: Toxicology Source Type: research

Assessment of lead exposure controls on bridge painting projects using worker blood lead levels
Publication date: Available online 10 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Kevin Guth, Marie Bourgeois, Giffe Johnson, Raymond Harbison (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 11, 2020 Category: Toxicology Source Type: research

Safety evaluation of Ochratoxin A and citrinin after 28 days repeated dose oral exposure to Wistar rats
Publication date: Available online 7 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Pankaj Ramji Jagdale, Indradev, Anjaneya Ayanur, Dhirendra Singh, Md Arshad, Kausar Mahmood Ansari (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 8, 2020 Category: Toxicology Source Type: research

Editorial Board
Publication date: July 2020Source: Regulatory Toxicology and Pharmacology, Volume 114Author(s): (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 8, 2020 Category: Toxicology Source Type: research

Deriving harmonised permitted daily exposures (PDEs) for paracetamol (acetaminophen) CAS #: 103-90-2
Publication date: Available online 6 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Kamila Gromek, William Hawkins, Tanja Bernier, Claudia Sehner, Eva Zeller, Markus Schwind, Thomas Pfister, Martin Kohan, Osahon Osalodor, Milica Glogovac, Gregor Tuschl, David Dolan, Ester Lovsin Barle (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 8, 2020 Category: Toxicology Source Type: research

How the 62-year old Delaney Clause continues to thwart science: Case study of the flavor substance β-myrcene
Publication date: Available online 6 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Susan P. Felter, Craig Llewelyn, Lisa Navarro, Xiaoling Zhang (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 8, 2020 Category: Toxicology Source Type: research

Response to “OECD 428 in vitro dermal absorption mass balance performance based on our in-house database of pesticide studies”
Publication date: Available online 6 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Felix M. Kluxen, Sébastien Grégoire, Andreas Schepky, Nicky J. Hewitt, Martina Klaric, Jeanne Y. Domoradzki, Edgars Felkers, Philip Fisher, Steven F. McEuen, Robert Parr-Dobrzanski, Eric Fabian, Christiane Wiemann (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 7, 2020 Category: Toxicology Source Type: research

A novel approach to monitor skin permeation of metals in vitro
Publication date: Available online 4 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Klara Midander, Linda Schenk, Anneli Julander (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 5, 2020 Category: Toxicology Source Type: research

Safety assessment of astaxanthin from Haematococcus pluvialis: Acute toxicity, genotoxicity, distribution and repeat-dose toxicity studies in gestation mice
Publication date: Available online 5 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Tingting Niu, Jiawei Zhou, Feng Wang, Rongrong Xuan, Juanjuan Chen, Wei Wu, Haimin Chen (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 5, 2020 Category: Toxicology Source Type: research

Meta-analysis of animal studies applied to short-term inhalation exposure levels of hazardous chemicals
Publication date: Available online 3 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Andrew J. Prussia, Joshua Hill, Cheryl R. Cornwell, Ram C. Siwakoti, Eugene Demchuk (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 4, 2020 Category: Toxicology Source Type: research

PBPK model reporting template for chemical risk assessment applications
Publication date: Available online 2 June 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Yu-Mei Tan, Melissa Chan, Amechi Chukwudebe, Jeanne Domoradzki, Jeffrey Fisher, C. Eric Hack, Paul Hinderliter, Kota Hirasawa, Jeremy Leonard, Annie Lumen, Alicia Paini, Hua Qian, Patricia Ruiz, John Wambaugh, Fagen Zhang, Michelle Embry (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 4, 2020 Category: Toxicology Source Type: research

Confidence interval function analysis to evaluate the risk of mesothelioma among an expanded international cohort of cosmetic talc miners and millers
Publication date: Available online 31 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Gary M. Marsh, A. Michael Ierardi (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - June 2, 2020 Category: Toxicology Source Type: research

Pulmonary toxicity of silver vapours, nanoparticles and fine dusts: A review
Publication date: Available online 28 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Niels Hadrup, Anoop K. Sharma, Katrin Loeschner, Nicklas R. Jacobsen (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 29, 2020 Category: Toxicology Source Type: research

Risk assessment of unintentional phthalates contaminants in cosmetics
Publication date: Available online 28 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Min Kook Kim, Kyu Bong Kim, Sungpil Yoon, Hyung Sik Kim, Byung-Mu Lee (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 29, 2020 Category: Toxicology Source Type: research

Toxicological testing of a photoactive phthalocyanine-based antimicrobial substance
Publication date: Available online 23 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Kristina Kejlová, Hana Bendová, Jan Chrz, Markéta Dvořáková, Lada Svobodová, Alena Vlková, Lubomír Kubáč, Radka Kořínková, Jiří Černý, Danuše Očadlíková, Marian Rucki, Tuula Heinonen, Dagmar Jírová, Silvia Letašiová, Helena Kandarova, Hana Kolářová (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 25, 2020 Category: Toxicology Source Type: research

Effect of low- and high-level groundwater arsenic on peripheral blood and lung function of exposed rural women
Publication date: Available online 23 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Priyanka Prasad, Nivedita Sarkar, Dona Sinha (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 25, 2020 Category: Toxicology Source Type: research

Toxicological evaluation of exosomes derived from human adipose tissue-derived mesenchymal stem/stromal cells
Publication date: Available online 22 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Dae Hyun Ha, Sun-Don Kim, Joon Lee, Hyuck Hoon Kwon, Gyeong-Hun Park, Steve Hoseong Yang, Jae Yoon Jung, Jun Ho Lee, Sang Rae Park, Jinkwon Youn, Sang Hee Lee, Ji Eun Kim, Jihye Lim, Hyun-Kul Lee, Byong Seung Cho, Yong Weon Yi (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 23, 2020 Category: Toxicology Source Type: research

Hydroalcoholic extract of leaf of Arachis hypogaea L. (Fabaceae) did not induce toxic effects in the repeated-dose toxicity study in rats
Publication date: Available online 13 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Jocelene Filippin Cossetin, Amanda Spring de Almeida, Caren Tatiane de David Antoniazzi, Sabrina Qader Kudsi, Ana Martiele Engelmann, Camille Gaube Guex, Juliana Sorraila de Oliveira, Maria Carolina Theisen, Camila Santos Ritter, Pedro Henrique Doleski, Evelyne da Silva Brum, Diéssica Padilha Dalenogare, Diulle Spat Peres, Francieli Guedes Pintos, Cinthia Melazzo de Andrade, Daniela Bitencourt Rosa Leal, Sara Marchesan Oliveira, Liliane de Freitas Bauermann, Roberta Cougo Riéffel, Michele Rorato Sagrillo (So...
Source: Regulatory Toxicology and Pharmacology - May 14, 2020 Category: Toxicology Source Type: research

An interim internal Threshold of Toxicologic Concern (iTTC) for chemicals in consumer products, with support from an automated assessment of ToxCast™ dose response data
Publication date: Available online 11 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Karen L. Blackburn, Gregory Carr, Jane L. Rose, Bastian G. Selman (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 11, 2020 Category: Toxicology Source Type: research

Derivation of biomonitoring equivalents (BE values) for bismuth
Publication date: Available online 11 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Devika Poddalgoda, Sean M. Hays, Andy Nong (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 11, 2020 Category: Toxicology Source Type: research

Application of structural and functional pharmacokinetic analogs for physiologically based pharmacokinetic model development and evaluation
Publication date: Available online 5 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Corie A. Ellison, Shengde Wu (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 6, 2020 Category: Toxicology Source Type: research

Editorial Board
Publication date: June 2020Source: Regulatory Toxicology and Pharmacology, Volume 113Author(s): (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 6, 2020 Category: Toxicology Source Type: research

An evaluation of the genotoxicity and subchronic toxicity of the peel extract of Ponkan cultivar ‘Ohta ponkan’ (Citrus reticulata Blanco) that is rich in nobiletin and tangeretin with anti-dementia activity
Publication date: Available online 1 May 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Akira Nakajima, Kiyomitsu Nemoto, Yasushi Ohizumi (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 2, 2020 Category: Toxicology Source Type: research

Dietary pectin at 0.2% in milk replacer did not inhibit growth, feed intake, or nutrient digestibility in a 3-week neonatal pig study
Publication date: Available online 29 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): S.A. Fleming, J.D. Richards, C.L. Bradley, X. Pan, Q. Li, R.N. Dilger (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 30, 2020 Category: Toxicology Source Type: research

Derivation of whole blood biomonitoring equivalents for titanium for the interpretation of biomonitoring data
Publication date: Available online 30 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): S. Ramoju, M.E. Andersen, A. Nong, N. Karyakina, N. Shilnikova, K. Krishnan, D. Krewski (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 30, 2020 Category: Toxicology Source Type: research

A 90-day repeated oral dose toxicity study of four stereoisomers of 2,4-dimethyl-4-phenyltetrahydrofuran, a synthetic flavoring substance, in F344 rats
Publication date: Available online 27 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Tetsuya Ide, Yasuko Mizuta, Jun-ichi Akagi, Naoko Masumoto, Naoki Sugimoto, Kyoko Sato, Kumiko Ogawa, Young-Man Cho (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 28, 2020 Category: Toxicology Source Type: research

New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop
Publication date: Available online 23 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Catherine Mahony, Randolph S. Ashton, Barbara Birk, Alan R. Boobis, Tom Cull, George P. Daston, Lorna Ewart, Thomas B. Knudsen, Irene Manou, Sebastian Maurer-Stroh, Luigi Margiotta-Casaluci, Boris P. Müller, Pär Nordlund, Ruth A. Roberts, Thomas Steger-Hartmann, Evita Vandenbossche, Mark R. Viant, Mathieu Vinken, Maurice Whelan, Zvonar Zvonimir (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 25, 2020 Category: Toxicology Source Type: research

Acute toxicity “six-pack” studies supporting approved new drug applications in the U.S., 2015–2018
Publication date: Available online 23 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Joseph Manuppello, Kristie Sullivan, Elizabeth Baker (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 25, 2020 Category: Toxicology Source Type: research

Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across: An EFSA funded project
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Romualdo Benigni, Rositsa Serafimova, Juan Manuel Parra Morte, Chiara Laura Battistelli, Cecilia Bossa, Alessandro Giuliani, Elena Fioravanzo, Arianna Bassan, Mojca Fuart Gatnik, James Rathman, Chihae Yang, Aleksandra Mostrag-Szlichtyng, Oliver Sacher, Olga Tcheremenskaia (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Regulating human safety: How dose selection in toxicity studies impacts human health hazard assessment and subsequent risk management options
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Marjolijn Woutersen, Andre Muller, Marja E.J. Pronk, Nicole H.P. Cnubben, Betty C. Hakkert (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Chuanyang Xu, Lijuan Sun, FengLing Ren, Ping Huang, Zhuang Tian, Jiazhen Cui, Wangqian Zhang, Shuning Wang, Kuo Zhang, Lei He, Wei Zhang, Cun Zhang, Qiang Hao, Yingqi Zhang, Meng Li, Weina Li (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management
Publication date: Available online 22 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Minne B. Heringa, Nicole H.P. Cnubben, Wout Slob, Marja E.J. Pronk, Andre Muller, Marjolijn Woutersen, Betty C. Hakkert (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

Chronic inflammation, Adverse Outcome Pathways, and risk assessment: A diagrammatic exposition
Publication date: Available online 21 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Louis Anthony Cox, Julie E. Goodman, Anna M. Engel (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 23, 2020 Category: Toxicology Source Type: research

An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs)
Publication date: Available online 20 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Amy M. Avila, Ilona Bebenek, Jessica A. Bonzo, Todd Bourcier, Karen L. Davis Bruno, David B. Carlson, John Dubinion, Ikram Elayan, Wafa Harrouk, Shwu-Luan Lee, Donna L. Mendrick, Jill C. Merrill, Jackye Peretz, Emily Place, Muriel Saulnier, Ronald L. Wange, Jia Yao, Dong Zhao, Paul C. Brown (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 21, 2020 Category: Toxicology Source Type: research

Integration of in vitro data from three dimensionally cultured HepaRG cells and physiologically based pharmacokinetic modeling for assessment of acetaminophen hepatotoxicity
Publication date: Available online 18 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Chi Zhang, Qiang Zhang, Jin Li, Lin Yu, Fengxiang Li, Weiwei Li, Yujie Li, Hui Peng, Jun Zhao, Paul L. Carmichael, Yunfang Wang, Shuangqing Peng, Jiabin Guo (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 20, 2020 Category: Toxicology Source Type: research

Regulatory landscape of dietary supplements and herbal medicines from a global perspective
Publication date: Available online 16 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Shraddha Thakkar, Elke Anklam, Alex Xu, Franz Ulberth, Jing Li, Bo Li, Marta Hugas, Nandakumara Sarma, Scott Crerar, Sibyl Swift, Takashi Hakamatsuka, Valeriu Curtui, William Yan, Xingchao Geng, William Slikker, Weida Tong (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 17, 2020 Category: Toxicology Source Type: research

Safety evaluation of water extract of Gastrodia elata Blume: Genotoxicity and 28-day oral toxicity studies
Publication date: Available online 9 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Kuan-Hung Lu, Guan-Ling Ou, Hui-Ping Chang, Wei-Cheng Chen, Shing-Hwa Liu, Lee-Yan Sheen (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 10, 2020 Category: Toxicology Source Type: research

Toxicological evaluation of, red rice yeast extract, Xuezhikang: Acute, 26-week chronic and genotoxicity studies
Publication date: Available online 9 April 2020Source: Regulatory Toxicology and PharmacologyAuthor(s): Yonglin Gao, Xiao Chen, Chunmei Li, Hongbo Wang, Jingwei Tian, Fenghua Fu (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 10, 2020 Category: Toxicology Source Type: research