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Lateral trochanteric pain following total hip arthroplasty: radiographic assessment of altered biomechanics as a potential aetiology
ConclusionNo relationship was found between LTP and femoral offset or femoral centre of rotation. Disruption of the soft tissues during a lateral approach with resultant abductor tear, tendon defects and tendinitis might play a role in LTP and explain the apparent efficacy of corticosteroid injections. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 15, 2018 Category: General Medicine Source Type: research

Transfer of critically ill adults —assessing the need for training
ConclusionsOrganisational, communication and individual issues need to be considered when addressing problems associated with IHT. A multifaceted approach is needed, with a focus on organisational solutions in the form of checklists as well as educational interventions such as interprofessional education initiatives. Further studies on implementation of educational initiatives will add to the findings we report here. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 12, 2018 Category: General Medicine Source Type: research

Correction to: Epidemiology of chronic hepatitis B virus in Ireland using routinely collected surveillance and administrative data, 2004 –2014
AbstractThe original version contained a mistake. The published version of this article incorrectly lists Lelia Thornton as Thornton Thornton. The correct author name is presented above. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 10, 2018 Category: General Medicine Source Type: research

Aciclovir-induced acute kidney injury in patients with ‘suspected viral encephalitis’ encountered on a liaison neurology service
ConclusionsLiaison neurologists and general physicians need to be aware that aciclovir may cause AKI attributed to distal intra-tubular crystal nephropathy. Daily fluid balance and renal function monitoring are essential because AKI may arise even with intensive pre-hydration. Prognosis is good if identified early and actively treated. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 6, 2018 Category: General Medicine Source Type: research

Risk reduction surgery (RRS) for tubo-ovarian cancer in an Irish gynaecological practice: an analysis of indications and outcomes
ConclusionMore than 60% of women undergoing RRS were BRCAm negative or untested. Counselling of high-risk women without defined germline mutations remains a challenge for gynaecologists because the likelihood of removing STIC lesions or occult invasive cancer is low. Removal of coincidental pathology may give added value to RRS in these women. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 3, 2018 Category: General Medicine Source Type: research

A cadaveric study of aortic arch variation in an Irish population
ConclusionThis is the first study documenting the rates of variation of the AA in Ireland. Variation of AA branching is of radiological and surgical significance, particularly in the diagnosis and treatment of thoracic and head and neck diseases. Awareness of these variations is particularly relevant for interventionalists who access these vessels during endovascular surgery. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 29, 2017 Category: General Medicine Source Type: research

A prospective pilot study of Dilapan-S compared with Propess for induction of labour at 41+ weeks in nulliparous pregnancy
ConclusionsDilapan-S is an acceptable, safe form of induction of labour in post-dates uncomplicated nulliparous pregnancy. No cases of hyperstimulation were found, and therefore, Dilapan-S may be a suitable option for outpatient induction of labour in low-risk post-dates nulliparas. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 21, 2017 Category: General Medicine Source Type: research

From a direct oral anticoagulant to warfarin: reasons why patients switch
This study was an analysis of prospectively collected data from a 4-year period surveying a warfarin dose adjustment clinic in a large city centre hospital with the primary objective to identify these reasons. In our clinic with 1791 patients annually under review, 40 patients were identified as having switched from a DOAC to warfarin with the most common reasons for switching being bleeding, re-thrombosis and renal deterioration. Other reasons included medication interactions, side effects, antiphospholipid syndrome, valvular replacement or arterial embolism. Clinical events following warfarin commencement were also recor...
Source: Irish Journal of Medical Science - December 21, 2017 Category: General Medicine Source Type: research

Prevalence of pulmonary hypertension in systemic lupus erythematosus: a meta-analysis
ConclusionsPH is prevalent in SLE patients, but it was significantly different between different gender, age, regions, year of publication, and diagnostic methods. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 18, 2017 Category: General Medicine Source Type: research

Elective ambulatory surgical care in Ireland —why it needs to be better coded, classified and managed
ConclusionOur findings show that many day cases should have been performed as outpatient procedures and that there were variations in coding and practices between hospitals that could not be easily explained. Outpatient procedure coding and a better, more consistent, classification of day cases are both required to better manage this group of patients. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 12, 2017 Category: General Medicine Source Type: research

Epidemiology of chronic hepatitis B virus in Ireland using routinely collected surveillance and administrative data, 2004 –2014
This study aimed to describe the epidemiology of chronic HBV in Ireland between 2004 and 2014 using routine surveillance data and identify and interrogate additional data sources in Ireland to complement the interpretation of HBV surveillance data.MethodsRoutinely collected passive surveillance data of notified cases of HBV infection were collated for 2004 –2014. Additional data sources relating to primary liver cancer and cirrhosis were collated, including hospital discharge data (2005–2013), diagnoses of primary liver cancer (2004–2013), and deaths (2007–2014). Publicly available immigration (2004...
Source: Irish Journal of Medical Science - December 9, 2017 Category: General Medicine Source Type: research

Contrast-enhanced ultrasound of the kidney: a single-institution experience
ConclusionCEUS is a valuable alternative to CT in assessing complex cystic or solid renal lesions where iodinated CT contrast or gadolinium is inappropriate. CEUS can also refine the Bosniak category of atypical cystic renal lesions and help facilitate treatment decisions. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 7, 2017 Category: General Medicine Source Type: research

Evaluation of the effectiveness and patients ’ contentment with transanal haemorrhoidal artery dearterialisation and mucopexy (THD) for treatment of haemorrhoidal disease: a 6-year study
AbstractIntroductionWith high incidence of haemorrhoidal disease and significant complication rates of traditional haemorrhoidectomy procedures, transanal haemorrhoidal artery ligation and mucopexy (THD) emerges as a minimally invasive procedure with superior results. However, it is crucial that effectiveness of results and patient satisfaction be gauged based on post-operative experience, symptomology and recurrence.AimOur aim is to provide a long-term analysis of efficacy and patient ’s satisfaction for the procedure, for the largest patient population, in correlation to presenting symptoms and degree of haemorrhoi...
Source: Irish Journal of Medical Science - December 6, 2017 Category: General Medicine Source Type: research

Epidemiological changes in rubella IgG antibody levels detected in antenatal women from a retrospective rubella seroprevalence study
AbstractBackgroundRubella is caused by the rubella virus, a single-stranded RNA virus of theTogaviridae family. The most severe complications of rubella in adult women occur during pregnancy when infection can lead to miscarriage, stillbirth or congenital rubella syndrome. Antenatal rubella susceptibility screening is no longer performed in England, Scotland or Wales but continues in Northern Ireland.AimThe aims of this seroprevalence study were to (1) determine amongst women presenting for antenatal care the percentage of women who are rubella susceptible, rubella immune and those with equivocal rubella antibody levels by...
Source: Irish Journal of Medical Science - December 5, 2017 Category: General Medicine Source Type: research

Aetiological profile and treatment outcomes of epistaxis at a major teaching hospital: a review of 721 cases
ConclusionMore return and admitted patients presented at out-of-hours times with less clinical staff on site. Most non-admitted patients received no treatment. These factors possibly lead to increased stress on the ENT casualty service. Cautery and nasal packing are the most common treatment modalities in first-time and admitted patients yet result in considerable rates of representation. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 2, 2017 Category: General Medicine Source Type: research

Cognitive assessment of older adults in general practice: the collateral history
ConclusionsDespite recognition of the utility and importance of the collateral history, the vast majority of GPs report having never received training in obtaining one and do not use structured tools to guide their interview. Further emphasis on the informant history as a distinct clinical entity on medical curricula and increasing emphasis on the availability of structured informant tools are warranted. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 2, 2017 Category: General Medicine Source Type: research

Progress of statistical analysis in biomedical research through the historical review of the development of the Framingham score
ConclusionClinically applicable predictive model should be a trade-off between all abovementioned statistical metrics, a trade-off between calibration and discrimination, accuracy and decision-making, costs and benefits, and quality and quantity of patient ’s life. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - December 2, 2017 Category: General Medicine Source Type: research

Correction to: MRI and multiple sclerosis —the evolving role of MRI in the diagnosis and management of MS: a clinician’s perspective
AbstractThe original version of this article unfortunately contained a mistake. The presentation of Table  1 was incorrectly captured. The Publisher regrets that it introduced errors to Table  1 during the typesetting of the article. The corrected Table is given below. The original article has been corrected. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 28, 2017 Category: General Medicine Source Type: research

Long-term endurance training increases serum cathepsin S levels in healthy female subjects
ConclusionsWe could show a significant increase of circulating CS levels in healthy female subjects induced by long-term physical activity. CS, occurring in the tumour microenvironment, is well-known to promote tumour growth, e.g. by ameliorating angiogenesis. However, the role of circulating CS in cancer growth is not clear. As physical activity is known as preventive intervention, in particular concerning breast and colorectal cancers, and long-term physical activity leads to an increase of CS levels in female subjects, circulating CS might even be involved in this protective effect.Trial registrationClinical trial regis...
Source: Irish Journal of Medical Science - November 27, 2017 Category: General Medicine Source Type: research

Direct to consumer genetic testing —law and policy concerns in Ireland
ConclusionsIn consideration of the ethical and legal challenges, this paper highlights the regulation of DTC genetic testing as a growing concern in Ireland, recognising its importance to both the scientific community as well as in respect of enhancing consumer confidence in such technologies. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 25, 2017 Category: General Medicine Source Type: research

MRI and multiple sclerosis ––the evolving role of MRI in the diagnosis and management of MS: the radiologist’s perspective
AbstractMagnetic resonance imaging (MRI) plays an integral role in the management of multiple sclerosis (MS), from both diagnostic and therapeutic perspectives. This 2-part review aims to detail the evolving and expanding role of MRI for both radiologists and neurologists. In this article, we discuss the diagnostic criteria for MS relevant to radiologists, as well as its varying imaging manifestations. The role of MRI in therapeutic modification and complications are discussed. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 25, 2017 Category: General Medicine Source Type: research

Smartphones in clinical practice: doctors ’ experience at two Dublin paediatric teaching hospitals
ConclusionSmartphone usage is universal among healthcare professionals and their influence is growing in patient care. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 23, 2017 Category: General Medicine Source Type: research

Dermatomyositis and colorectal cancer: a systematic review
ConclusionIt is of paramount importance to perform a systematic diagnostic workup for malignancy, always including colonoscopy, in DM patients, since there is a high incidence of cancer in DM patients. Surgical treatment of colorectal tumors should precede the treatment of DM, as DM will frequently regress after a successful resection of malignancy. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 22, 2017 Category: General Medicine Source Type: research

Vitamin D supplementation in pregnancy —a survey of compliance with recommendations
ConclusionsOf the women surveyed, 74.3% reported supplementation with vitamin D, either knowingly or unknowingly. Public health initiatives need to utilize this relatively safe, low-cost intervention to maximize maternal and fetal health. This could reduce the rates of antenatal conditions with associated high morbidity and healthcare burden such as gestational diabetes and preeclampsia. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 20, 2017 Category: General Medicine Source Type: research

UCD School of Medicine, Summer Student Research Awards 2017, 4th October 2017, UCD, Dublin, Ireland
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 18, 2017 Category: General Medicine Source Type: research

The effect of SMS (text message) reminders on attendance at a community adult mental health service clinic: do SMS reminders really increase attendance?
This study aimed to determine if sending SMS ( ‘short message service’ or text message) reminders to patients before appointments reduced non-attendance.MethodsWe collected outpatient data at Ballyfermot and Lucan Community Adult Mental Health Service, Dublin, Ireland during 6-month periods (a) immediately prior to the introduction of SMS reminders for outpatient appointments; (b) immediately following the introduction of SMS reminders; and (c) two and a half years later.ResultsIn the 6-month period prior to SMS reminders, 2170 outpatient appointments were offered and there was a 22.2% non-attendance rate. In t...
Source: Irish Journal of Medical Science - November 16, 2017 Category: General Medicine Source Type: research

Comparing reactive oxygen species and DNA fragmentation in semen samples of unexplained infertile and healthy fertile men
ConclusionsThe higher levels of intracellular ROS and DNA fragmentation in the semen samples of unexplained infertile couples and their causes might be considered as an important factor related to diagnosis and treatment of the unexplained infertile couples. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 15, 2017 Category: General Medicine Source Type: research

Cadaveric simulation: a review of reviews
ConclusionCadavers are an effective medium for surgical teaching, and it may be appropriate for them to be used whenever surrounding conditions such cost and availability allow. Further research is required to provide evidence on whether there is equivalence between cadavers and other educational media which may not bear the same shortcomings. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 14, 2017 Category: General Medicine Source Type: research

Patient safety ward round checklist via an electronic app: implications for harm prevention
ConclusionsThe baseline audit demonstrated significant practice bias on daily ward rounds which tended to omit several key-proven patient safety practices such as prompting hand decontamination and obtaining up to date reports from nursing staff. Results of the intervention arm demonstrate the feasibility of using the Checklist App on daily ward rounds. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 6, 2017 Category: General Medicine Source Type: research

Outcomes from a community-based hypertension educational programme: the West of Ireland Hypertension study
This study aims to explore the impact of a structured hypertension educational intervention on patient knowledge, lifestyle behaviours and blood pressure control.DesignAn observational, prospective cohort design was selected.MethodsParticipants were recruited through a public blood pressure screening event in a community-based setting. They were asked to complete a self-report questionnaire followed by an assessment of their blood pressure. Participants with high blood pressure were randomly assigned to either a control group or an intervention group. Those in the intervention group received an educational intervention on ...
Source: Irish Journal of Medical Science - November 6, 2017 Category: General Medicine Source Type: research

Attitudes to trainee-led surgical mentoring
ConclusionOur study, the first to describe the experience and potential benefits of a surgical trainee-led mentoring programme in Ireland, demonstrates a significant appetite amongst students and surgical trainees for mentorship. Further evaluation of the importance of mentoring programmes and the role of trainees in their delivery are necessary. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 4, 2017 Category: General Medicine Source Type: research

Prenatal surgery for spina bifida: a therapeutic dilemma. Proceedings of the SHINE conference, Belfast
AbstractThis is a transcript of a scientific conference on the subject of prenatal surgery for spina bifida. It represents the views of three patients, an obstetrician, a postnatal neurosurgeon, a neonatologist, a paediatric neurologist, two surgeons who practice open spina bifida foetal surgery, a fetoscopic surgeon and an obstetrician experienced in randomised trials and systematic reviews. Implications for current practice and recommendations for future research are also discussed in detail. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 3, 2017 Category: General Medicine Source Type: research

Assessment of patients ’ attitudes towards weight loss in an Irish general practice setting
ConclusionOverweight or obese patients are more likely to underestimate their BMI. GPs are not discussing weight management with patients who would benefit the most. There is a poor referral rate to weight loss services. Patients are happy to discuss their weight with their GP but are aware that time management is an issue in their consultations. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 3, 2017 Category: General Medicine Source Type: research

Proceedings of the RAMI Section of OtoRhinoLaryngology Head and Neck Surgery (ORL HNS) Spring Meeting, Saturday 8th April 2017
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 1, 2017 Category: General Medicine Source Type: research

Desires versus reality of medical and health science summer student research opportunities
ConclusionDespite the desire by summer research students to be involved in early components of research project design, this only occasionally occurs. Summer student research programs should explore the possibility of early involvement of students in the research design phase. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 27, 2017 Category: General Medicine Source Type: research

Using the theory of planned behavior framework for designing interventions related to organ donation
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 24, 2017 Category: General Medicine Source Type: research

Changing trends in postoperative cataract care: impact of electronic patient records in optometrist-delivered shared care
This study evaluates a community optometrist-delivered postoperative care scheme in patients discharged from the hospital ophthalmology department following uncomplicated cataract surgery.AimThe aim of this study is to assess the efficacy of electronic patient records (EPR) in facilitating co-managed cataract care.MethodsWe performed a retrospective analysis of a prospectively maintained Medisoft EPR database of postoperative cataract review data at a single centre, Sligo University Hospital (SUH), which serves a large and predominantly rural catchment area. All patients undergoing cataract surgery at SUH from October 2012...
Source: Irish Journal of Medical Science - October 23, 2017 Category: General Medicine Source Type: research

Implementing an electronic clinical handover system in a university teaching hospital
ConclusionElectronic clinical handover is feasible and practical within the Irish healthcare system. In addition, it was found in our study to be attractive and effective to physicians without increasing their workload. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 23, 2017 Category: General Medicine Source Type: research

Geographic distribution and incidence of Lyme borreliosis in the west of Ireland
ConclusionsIncreased awareness may explain the increase in requests. There is no indication of an increase in incidence. As many GPs treat suspected Lyme borreliosis empirically without testing and as antibody may be undetectable early in the course of illness, the true incidence of infection is likely to exceed the number of laboratory-confirmed cases. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 23, 2017 Category: General Medicine Source Type: research

In recognition of Ireland ’s contemporary medical scientists—Ted Dinan, Timothy O’Brien, Michael Hutchinson, Desmond FitzGerald, Michael Gibney, Mary Cannon and Fergal O’Gara
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 19, 2017 Category: General Medicine Source Type: research

Pituitary plasmacytoma —a rare presentation of multiple myeloma
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 18, 2017 Category: General Medicine Source Type: research

Undergraduate basic surgical skills education: impact on attitudes to a career in surgery and surgical skills acquisition
ConclusionThe introduction of surgical skills teaching to the undergraduate medical curriculum has a positive impact on students ’ attitudes towards surgery and accelerates basic technical skills development. Consideration should be given to development of a standardised undergraduate core curriculum in basic surgical skills teaching. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 17, 2017 Category: General Medicine Source Type: research

Surgical management of splenic marginal zone lymphoma
ConclusionBased on the data obtained, current practice requires defined guidelines and centralised care. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 17, 2017 Category: General Medicine Source Type: research

Can the gastrointestinal microbiota be modulated by dietary fibre to treat obesity?
AbstractRecent research suggests that the human gastrointestinal microbiota is greatly involved in yielding, storing and expending energy from the diet; therefore, it may be a further factor in linking diet to obesity. The gut microbial composition is affected by diet throughout the human lifespan, and is highly dynamic and efficient in response to dietary alterations in particular to dietary fibre intake. Short-chained fatty acids (SCFA) are the bi-product of fibre fermentation and have both obesogenic and anti-obesogenic properties. The production of specific forms of SCFAs depends on the microbes available in the gut an...
Source: Irish Journal of Medical Science - October 16, 2017 Category: General Medicine Source Type: research

Non-attendance of vulnerable populations within epilepsy outpatient services in Ireland
ConclusionsThis study provided evidence that in certain groups of patients, clinicians may need to explore other care delivery models due to high DNA rates. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 14, 2017 Category: General Medicine Source Type: research

Clinical evaluation for sublingual immunotherapy with Dermatophagoides farinae drops in adult patients with allergic asthma
AbstractPurposeThe efficacy and safety of sublingual immunotherapy (SLIT) in house dust mite-induced allergic asthma (AA) have yet to be firmly established, especially in adult patients. Our objective is to evaluate the efficacy of SLIT withDermatophagoides farinae drops in adult patients with AA.MethodsOne hundred and thirty-four adult patient data with house dust mite (HDM)-induced AA who had been treated for 2  years were collected. These patient data that we collected were divided into the SLIT group (n = 85) and control group (n = 49). All patients were treated with low to moderate dose of inh...
Source: Irish Journal of Medical Science - October 14, 2017 Category: General Medicine Source Type: research

MRI and multiple sclerosis —the evolving role of MRI in the diagnosis and management of MS: a clinician’s perspective
AbstractThe diagnosis of multiple sclerosis (MS) is based on a history consistent with demyelination of the central nervous system and corresponding physical signs on examination. However, this diagnosis is supported radiologically using magnetic resonance imaging (MRI). At present, MRI serves as the most reliable and widely available biomarker for the practising clinician to measure disease activity and treatment response in MS. As MRI remains central to both the diagnosis and management of MS, this paper provides proposed guidelines for its use in routine clinical practice. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 10, 2017 Category: General Medicine Source Type: research

Burnout and stress amongst interns in Irish hospitals: contributing factors and potential solutions
ConclusionsBurnout and stress are significant problems amongst doctors in Irish hospitals. Ensuring better preparation for clinical practice and awareness of support services is vital to tackle this issue. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 9, 2017 Category: General Medicine Source Type: research

Ultra-low dose of intravitreal bevacizumab in retinopathy of prematurity
AbstractAimWe aimed to investigate the effectivity of the 0.0625  mg dose of bevacizumab in patients with retinopathy of prematurity (ROP) and compare the results with 0.625 mg dose of intravitreal bevacizumab (IVB) injection.MethodsThe medical records of the patients with type 1 ROP who received IVB monotherapy were retrospectively reviewed. Demographic and clinical characteristics of the patients were recorded. The patients were classified into two groups with respect to received dose of bevacizumab as follows: group F (n = 46) (full dose of bevacizumab—0.625 mg/0.025 ml) and group L (...
Source: Irish Journal of Medical Science - October 7, 2017 Category: General Medicine Source Type: research

Irish Thoracic Society Annual Scientific Meeting 2017 10th - 11th November 2017, Limerick Strand Hotel, Limerick
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 1, 2017 Category: General Medicine Source Type: research