Trends in HbA1c and other biochemical outcomes of individuals with newly diagnosed type 1 diabetes
AbstractBackgroundThere is limited data on glycaemic control and cardiovascular risk factor management in newly diagnosed individuals with type 1 diabetes in the first 2 years.MethodsRetrospective, single centre study from the North West of England, newly diagnosed with type 1 diabetes between 2014 and 2018 (n = 58). HbA1c, blood pressure, lipids and body mass index (BMI) data were collected from electronic patient records from the time of diagnosis until the end of 2 years, stratified by age 16 –24 years or ≥ 25 years at presentation.ResultsFor those aged 16 –24 years (n = 31), median (IQR), HbA1c improved ...
Source: Irish Journal of Medical Science - November 24, 2020 Category: General Medicine Source Type: research

Clinical outcomes and epidemiology of intraocular foreign body injuries in Cork University Hospital, Ireland: an 11-year review
ConclusionsThis review provides important epidemiological data for IOFB injuries in Ireland. It also adds some useful information to the literature in relation to prognostic factors and lens status post IOFB injury. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 23, 2020 Category: General Medicine Source Type: research

Serum Lithium monitoring in non-psychiatric wards in a university hospital
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 23, 2020 Category: General Medicine Source Type: research

The impact of the first 24 h of loop diuretic on kidney function in acute decompensated heart failure
ConclusionIn patients with ADHF, the initial high dose of IV loop diuretics is associated with an increased risk of developing AKI. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 22, 2020 Category: General Medicine Source Type: research

Impact of changes in community psychiatric service provision on mental health presentations to the emergency department
ConclusionsRemoving a direct community access point for this group resulted in a substantial increase in ED presentations, many of which did not have physical needs. This study has implications for future policy to address the needs of this group, especially in light of the pandemic. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 21, 2020 Category: General Medicine Source Type: research

Resveratrol and cardiovascular system —the unfulfilled hopes
ConclusionDespite numerous articles and clinical studies, the convincing beneficial mechanisms of resveratrol as well as its health-promoting effects in cardiovascular diseases have not been clearly confirmed in humans. Therefore, there is a need for further clinical studies, especially randomized, double-blind, placebo-controlled trials to objectively confirm the possible health-promoting effects of this substance and to determine both the efficacy and safety, and possible therapeutic potential. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 21, 2020 Category: General Medicine Source Type: research

Vitamin D and SARS-CoV-2 infection —evolution of evidence supporting clinical practice and policy development
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 21, 2020 Category: General Medicine Source Type: research

Kidney-gut crosstalk in renal disease
ConclusionIn the present review, the main characteristics of kidney-gut crosstalk are described. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 20, 2020 Category: General Medicine Source Type: research

A snapshot of chronic obstructive pulmonary disease management in general practice in Ireland
ConclusionsThis study provides a comprehensive snapshot of care in Irish general practice for patients with COPD prior to introduction of the Chronic Disease Management programme (CDM). (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 20, 2020 Category: General Medicine Source Type: research

Optimal perioperative blood pressure management —the jury is still out
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 19, 2020 Category: General Medicine Source Type: research

Remdesivir versus ritonavir/lopinavir in COVID-19 patients
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 18, 2020 Category: General Medicine Source Type: research

A prospective study on the incidence of postponed time-sensitive urological procedures during the SARS-CoV-2 pandemic due to patient preference
ConclusionsThe incidence for patients postponing urological procedures due to the risk of acquiring nosocomial SARS-CoV-2 is 10%. Endourological procedures for urolithiasis are the most frequently postponed procedures by patients. This study demonstrates that a subset of patients will decline urgent urological surgery during the SARS-CoV-2 pandemic. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 17, 2020 Category: General Medicine Source Type: research

Lentigo maligna —an old disease under new light
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 16, 2020 Category: General Medicine Source Type: research

Maxillofacial space infection experience and risk factors: a retrospective study of 222 cases
AbstractBackgroundMaxillofacial space infection (MSI) experience review is beneficial for its management.AimTo identify potential risk factors predisposing to the exacerbation of MSI and a prolonged length of stay (LOS).MethodsWe performed a comprehensive retrospective review of medical records of 222 MSI patients admitted in Center of Stomatology during 1993 –2019.ResultsAbout 63.5% of 222 patients had an odontogenic infection, and submandibular space was the most involved space.Streptococcus spp. was the most common organism isolated (72.4%). Multiple-space cases had more systemic diseases, respiratory difficulty, ...
Source: Irish Journal of Medical Science - November 14, 2020 Category: General Medicine Source Type: research

Clinical presentations of pain in patients with COVID-19 infection
ConclusionsThe most common pain symptoms were myalgia/arthralgia and headache (69.17% and 50.37%) and found to be much higher than previously reported. Pain is one of the most common complaints of admission to the hospital in patients with COVID-19. Patients who apply to health institutions with pain complaints should be evaluated and questioned in suspicion of COVID-19 infection. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 14, 2020 Category: General Medicine Source Type: research

Implementation of a nurse-led lower urinary tract symptoms (LUTS) clinic reduces general urology clinic workload in a Model 4 Hospital: a pilot study in Tallaght University Hospital
ConclusionIntroduction of a CNS-led LUTS clinic has significantly reduced the number of patients requiring follow-up in general urology clinics, representing a quality improvement in service provision. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 14, 2020 Category: General Medicine Source Type: research

Mulla Sadra, the pioneer theorist in proposing “mental imagery as treatment”
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 11, 2020 Category: General Medicine Source Type: research

Reduced JKAP correlates with advanced disease features, inflammation, as well as increased exacerbation risk and severity in asthmatic children
ConclusionJKAP serves as a potential biomarker for asthmatic susceptibility, inflammation, exacerbation risk, and severity in children. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 6, 2020 Category: General Medicine Source Type: research

The provision of neuro-oncology and glioma neurosurgery during the SARS-CoV-2 pandemic: a single national tertiary centre experience
ConclusionThe provision of neuro-oncological surgery can be safely continued during respiratory illness epidemic or pandemic if a rigorous testing and staffing framework is implemented. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 5, 2020 Category: General Medicine Source Type: research

The mental health and well-being benefits of exercise during the COVID-19 pandemic: a cross-sectional study of medical students and newly qualified doctors in the UK
DiscussionExercise can help to benefit the well-being of medical students and interim foundation doctors. It is hoped that higher education providers and employers recognise the importance of promoting physical activity for the well-being of their students and staff, respectively. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 4, 2020 Category: General Medicine Source Type: research

Sociodemographic variables as predictors of adverse outcome in SARS-CoV-2 infection: an Irish hospital experience
We describe the organisational challenges faced in managing the surge and identified risk factors for mortality and ICU admission among hospitalised SARS-CoV-2-infected patients.MethodsAll hospitalised SARS-CoV-2 patients diagnosed between March 13 and May 1, 2020, were included. Demographic, referral, deprivation, ethnicity and clinical data were recorded. Multivariable regression, including age-adjusted hazard ratios (HR (95% CI), was used to explore risk factors associated with adverse outcomes.ResultsOf 257 inpatients, 174 were discharged (68%) and 39 died (15%) in hospital. Two hundred three (79%) patients presented f...
Source: Irish Journal of Medical Science - November 3, 2020 Category: General Medicine Source Type: research

A review: a new authentication protocol for real-time healthcare monitoring system
AbstractInternet of Things is a fast growing technology and a network of devices in which everything (smart objects or smart devices) are associated to the internet for effective exchange of information between these connected objects. Internet of Things (IoT) serves as a method for healthcare and acts as an essential part in broad range of real-time healthcare monitoring applications. Previous work shows networked sensor devices, either equipped on the body or embedded inside living being or a camera, make possible in gathering real-time information to evaluate physical and mental health state of the patient by collecting...
Source: Irish Journal of Medical Science - November 3, 2020 Category: General Medicine Source Type: research

Anxiety and depression in glioma patients: prevalence, risk factors, and their correlation with survival
This study aimed to investigate the risk factors and prognostic value of anxiety and depression in glioma patients.MethodsA total of 190 glioma patients who underwent resection were consecutively enrolled. Anxiety was assessed using hospital anxiety and depression scale (HADS) and Zung self-rating anxiety scale (SAS); depression was assessed with the use of HADS and Zung self-rating depression scale (SDS). All patients were followed up to death or 36 months. Overall survival (OS) was calculated according to the survival data.ResultsThe prevalence of anxiety ranged from 36.3 to 37.4%, and the prevalence of depression ranged...
Source: Irish Journal of Medical Science - November 2, 2020 Category: General Medicine Source Type: research

Saving time in the fracture clinic: 2 weeks post-operative plain films following open reduction and internal fixation of distal radius fractures do not affect management
ConclusionRepeat imaging at 2 weeks following distal radius ORIF did not change management of distal radius fractures in this study. Therefore, our data suggests 2-week plain films should not routinely be ordered for these patients which will reduce wait time and exposure to radiation. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 2, 2020 Category: General Medicine Source Type: research

The line between COVID-19 pandemic and rare bone diseases
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 2, 2020 Category: General Medicine Source Type: research

Paediatric asthma deaths in Ireland: 2006 –2016
ConclusionOur data suggests that most patients present in extremis and have little warning signs of severity of the attack. Better education on recognition of symptoms and initiation of action plans is required. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 13, 2020 Category: General Medicine Source Type: research

Trends and outcomes of non-traumatic major lower extremity amputations in an Irish tertiary referral hospital
ConclusionLEA for vascular pathology has significant morbidity and mortality, with long in-patient stays and short median survival; there is need to focus on improving quality of life in postoperative pathways. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 13, 2020 Category: General Medicine Source Type: research

Correction to: Homelessness, emergency care and mental health. Inner-city emergency department psychiatry referrals: a retrospective descriptive analysis
This article was published online with incorrect spelling of author name. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 12, 2020 Category: General Medicine Source Type: research

Embolization or disruption of thoracic duct and cisterna chyli leaks post oesophageal cancer surgery should be first line management for ECCG-defined type III chyle fistulae
This article is built around two recent cases, where interventional radiology to embolize and disrupt complex fistulae was successfully performed. The lessons from this experience will change practice at this centre to initial lymphangiography with a view to embolization or disruption of thoracic duct and cisterna chyli leaks as first line therapy for type III chyle leaks, with surgery reserved for where this fails. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 11, 2020 Category: General Medicine Source Type: research

The road to consultancy: an epidemiological study
ConclusionThis study highlights variations in postgraduate Irish medical training pathways and discrepancies in training requirements expected in each specialty. The establishment of a modern guideline for young trainees working towards consultancy may be imperative in ensuring trainees have insight into training requirements expected in their specialty. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 5, 2020 Category: General Medicine Source Type: research

Platelet-rich plasma injections for hip osteoarthritis: a review of the evidence
AbstractOsteoarthritis is a significant cause of chronic pain in the elderly population with hip osteoarthritis as one of the main causes of functional disability and joint pain in adults older than 55 years. Recently, platelet rich plasma (PRP) injections have been introduced for treatment of osteoarthritis. The aim of this systematic review is to assess its effectiveness in the management of hip osteoarthritis. We performed a search of the literature for published prospective studies that assessed the effectiveness of PRP injections in the treatment of hip osteoarthritis, with a minimum follow-up of 3 months. Primary out...
Source: Irish Journal of Medical Science - October 4, 2020 Category: General Medicine Source Type: research

The relationship between cognition, depression, fatigue, and disability in patients with multiple sclerosis
AbstractBackgroundMultiple sclerosis (MS) is a chronic, progressive, and neurodegenerative central nervous system disorder. MS usually causes disability, cognitive deficiency, fatigue, and depression symptoms.ObjectivesTo assess cognitive functions of people with MS (pwMS) and investigate the impact of depression, fatigue, and disability on cognitive functions.MethodsWe administered the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) battery to assess 200 pwMS. The Expanded Disability Status Scale (EDSS) was used to evaluate disability levels. Fatigue Severity Scale (FSS) and the Beck Depression In...
Source: Irish Journal of Medical Science - September 30, 2020 Category: General Medicine Source Type: research

Homelessness, emergency care and mental health. Inner-city emergency department psychiatry referrals: a retrospective descriptive analysis
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 30, 2020 Category: General Medicine Source Type: research

Pachydermodactyly: a systematic review
ConclusionsDiagnosis can be established in asymptomatic young patients through a congruent physical exam, regular analytic results and imaging tests that simply show swelling of soft tissue —a biopsy is generally not required for diagnosis. As pachydermodactyly’s course is asymptomatic and benign, knowledge about this condition is limited, which increases the likelihood of its underdiagnosis—it is important that clinicians know of pachydermodactyly in order to avoid misdiagnosis. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 30, 2020 Category: General Medicine Source Type: research

A brief literature review of the psychological benefits of volunteerism in watersports inclusion
AbstractThe 2009 National Guidelines on Physical Activity for Ireland assert that ‘all people with disabilities should be active’. Events such as the Watersports Inclusion Games invite individuals across the full spectrum of abilities to take part in physical activity in the form of adaptive watersports. This literature review aims to assess the value of inclusive watersport events such as this in the context of what is currently published on the motivation and benefits for volunteers in watersports inclusion. This is the first review that we are aware of on this subject. A literature review was performed using...
Source: Irish Journal of Medical Science - September 29, 2020 Category: General Medicine Source Type: research

Frequent but limited assessment of potentially concussed players in Gaelic Football: an opportunity to learn from other sports
ConclusionIn the GAA NFL, PCEs are often briefly assessed but rarely result in player removal. Introduction of video incident analysis and concussion substitutions, as in other sports, may reduce the long-term burden of SRC on Gaelic Football players. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 29, 2020 Category: General Medicine Source Type: research

Dietitians supporting breastfeeding: a survey of education, skills, knowledge and attitudes
ConclusionsFurther examination of the role of the dietitian and the establishment of expected competencies would provide a clear framework for future training and education of dietitians towards increasing breastfeeding prevalence in Ireland. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 28, 2020 Category: General Medicine Source Type: research

Rational use of shoulder MRI in the private setting: specialist-ordered MRIs influence clinical management significantly more often than primary care physicians
AbstractPurposeThe aim of this study was to determine the difference in proportion of shoulder MRIs that influence the management plan of shoulder patients based on whether MRI was ordered by a shoulder specialist, orthopaedic surgeon or primary care provider prior to referral to a specialist.MethodsThis observational analytical study was conducted in a private practice setting. Data were obtained from 153 MRIs performed on 151 patients. Seventy-seven MRIs were ordered by a specialist shoulder surgeon and 76 by a primary care provider (general practitioner, non-operative sports medicine physician or physiotherapist).Result...
Source: Irish Journal of Medical Science - September 28, 2020 Category: General Medicine Source Type: research

Partial compliance with symptom-based testing pathways reveals asymptomatic carriage of SARS-CoV-2 in Ireland
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 27, 2020 Category: General Medicine Source Type: research

Expert consensus for primary management of reproductive health: a Delphi study
ConclusionsThese recommendations could set the basis for a public health action plan for primary management of reproductive health. The findings may be applicable to any country whose health services system provides primary healthcare. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 27, 2020 Category: General Medicine Source Type: research

Association of RAGE with acute ischemic stroke prognosis in type 2 diabetes
In this study, the clinical significance of serum RAGE levels in acute ischemic stroke patients with type 2 diabetes was determined.MethodThree hundred seven patients (165 patients without diabetes and 142 patients with diabetes) with acute cerebral infarction (ACI) were enrolled over 3 consecutive months. On admission, their National Institute of Health Stroke Scale (NIHSS) scores were recorded. The clinical laboratory data of all subjects were collected, and their serum levels of RAGE were assayed using enzyme-linked immunosorbent assay (ELISA). On admission and 3 months after stroke, the clinical outcomes were assessed ...
Source: Irish Journal of Medical Science - September 27, 2020 Category: General Medicine Source Type: research

COVID-19 community assessment hubs in Ireland —the experience of clinicians
ConclusionAcademic departments, GPs and the Irish health system collaborated effectively to respond to the need for community assessment of COVID-19 patients. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 25, 2020 Category: General Medicine Source Type: research

Sepsis in surgical inpatients: under-recognised but with significant consequences
ConclusionSepsis was under-documented, and barriers exist with use of the national sepsis screening form. Frailty, which is a sepsis risk factor, should be assessed pre-operatively to maximise prevention. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 24, 2020 Category: General Medicine Source Type: research

Coronary computed tomography angiography versus invasive coronary angiography: medical staff perceptions and diagnostic interest in Gaza-Palestine
ConclusionEfficient diagnostic benefits of CCTA and overuse of ICA for stable CAD are documented. Clear diagnostic strategy with medical, ethical, and logistical issues should be considered when selecting the CCTA or ICA for diagnosis CAD. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 24, 2020 Category: General Medicine Source Type: research

Use of antipsychotics after traumatic brain injury
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 24, 2020 Category: General Medicine Source Type: research

Correction to: Validity of a dysphagia screening test following resection for head and neck cancer
The above article was published online with error in Table 5 and 6. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 24, 2020 Category: General Medicine Source Type: research

Recognizing dysphagia: implementation of an in-hospital screening protocol
AbstractBackgroundDysphagia affects up to 30% of hospitalized patients, and it is associated with numerous complications.AimsAssess the impact of a 24/7 dysphagia screening protocol in an Internal Medicine Unit regarding respiratory complications (such as aspiration pneumonia) as the primary outcome. Length of stay and discharge destination were secondary outcomes.MethodsCase-control hospital-based analysis comparing the outcomes before and after the implementation of the screening protocol. We analysed demographic data (such as age and gender) and clinical data (presence of dysphagia, vascular risk factors and other comor...
Source: Irish Journal of Medical Science - September 21, 2020 Category: General Medicine Source Type: research

Atypical presentation of COVID-19 in hospitalised older adults
ConclusionOlder patients with atypical presentation of COVID-19 in the community are equally susceptible to poor outcomes. Early detection may improve outcomes and limit community transmission. Primary care practitioners should be vigilant and consider prompt onward referral. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 20, 2020 Category: General Medicine Source Type: research

Interleukin-1 β, interleukin-6, and interleukin-17A as indicators reflecting clinical response to celecoxib in ankylosing spondylitis patients
ConclusionSerum IL-1 β, IL-6, and IL-17A serve as indicators for predicting clinical response to celecoxib in AS patients, which may assist with the optimization of personalized treatment. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 20, 2020 Category: General Medicine Source Type: research

The challenges of international comparisons of COVID-19
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 20, 2020 Category: General Medicine Source Type: research