Maximal exercise outcomes with a face mask: the effects of gender and age differences on cardiorespiratory responses
ConclusionThe surgical mask use affected the maximal exercise capacity of middle-aged participants more than young participants. Although males performed better than females in tests without masks, the decrease in exercise capacity with mask use was greater than in females. Advanced age and male gender may be factors that need more attention during exercise with mask use.Trial registration number and dateNCT04498546 —02/17/2021. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 26, 2021 Category: General Medicine Source Type: research

Segmentation of intentions towards COVID-19 vaccine acceptance through political and health behaviour explanatory models
ConclusionsWhile the ‘right thing to do’ is clear when viewed through a lens of scientific expert advice, this is precisely the paradigm which populist movement rejects. Segmentations, such as the outputs from this study, validate the importance of proactively engaging with diverse communities both on and offline an d afford a framework for developing and evaluating more refined, targeted, policies and interventions. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 26, 2021 Category: General Medicine Source Type: research

Development and validation of a tool for evaluating YouTube-based medical videos
ConclusionCollectively, our findings indicated that the MQ-VET is a valid and reliable tool that will help to standardize future evaluations of online medical videos. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 25, 2021 Category: General Medicine Source Type: research

Neutrophil gelatinase associated lipocalin in predicting postoperative acute kidney injury in elderly
This study aimed to examine the potential utility of plasma neutrophil gelatinase associated lipocalin levels in early prediction of AKI in geriatric patients undergoing laparotomic oncological surgery.MethodsThis prospective single-center cohort study included 60 geriatric patients ( ≥ 65 years of age) that underwent major oncologic surgery with laparotomy. Perioperative measurements of plasma creatinine, blood urinary nitrogen, plasma lactate, urine output, and neutrophil gelatinase associated lipocalin (NGAL) were made. Patients were followed for AKI development, which is the primary outcome measure, and ...
Source: Irish Journal of Medical Science - November 25, 2021 Category: General Medicine Source Type: research

Impact of the COVID-19 pandemic on provision and outcomes of emergency abdominal surgery in Irish public hospitals
ConclusionsSignificant improvements in patient flow following admission for EAS during the pandemic were observed. These changes were not associated with greater mortality nor increased readmission rates and offer important insights into optimal delivery of EAS services. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 25, 2021 Category: General Medicine Source Type: research

Physical activity and exercise benefits/barriers in mothers of children with motor disabilities
ConclusionThis study has revealed that the physical activity levels of mothers of children with motor disabilities are low, and this is related to the gross motor function level of the children. The focus should be on increasing the physical activity levels of mothers of children with motor disabilities. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 25, 2021 Category: General Medicine Source Type: research

Management of “torus” or “buckle” fractures of the distal radius: a systematic review
ConclusionsCurrent research indicates that torus fractures should be managed with a removable splint supplied in A&E and worn for 3  weeks. There is no need for fracture clinic follow-up or repeat radiological imaging once patients are given adequate information at the time of diagnosis. This would represent both an economical and resource saving for patients, parents and the health service. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 22, 2021 Category: General Medicine Source Type: research

The relation of circulating cell division cycle 42 expression with Th1, Th2, and Th17 cells, adhesion molecules, and biochemical indexes in coronary heart disease patients
This study aimed to evaluate CDC42 expression, its correlation with Th1, Th2, and Th17 cells, adhesion molecules, and biochemical indexes in CHD patients.MethodsOne hundred two CHD patients and 50 controls were enrolled. CDC42 expression in peripheral blood mononuclear cells was assessed by reverse transcription quantitative polymerase chain reaction in all participants. In CHD patients, Th1, Th2, and Th17 cells were detected by flow cytometric analysis; meanwhile, serum levels of inflammatory cytokines and adhesion molecules were detected by enzyme-linked immunosorbent assay.ResultsCDC42 was lower in CHD patients (median ...
Source: Irish Journal of Medical Science - November 22, 2021 Category: General Medicine Source Type: research

A retrospective cohort study of outcomes in hospitalised COVID-19 patients during the first pandemic wave in Ireland
ConclusionThis study provides patient-level epidemiological characterisation of hospitalisations during the first COVID-19 pandemic wave in Ireland. The higher risk of adverse outcomes in older age groups supports the age-based prioritisation of COVID-19 vaccinations currently used in Ireland. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 19, 2021 Category: General Medicine Source Type: research

Implications of a diagnosis of atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) on prostate biopsy: a 5-year follow-up study
AbstractBackgroundIn the era of active surveillance of low- and intermediate-risk prostatic cancer, a reconsideration of the implications of a biopsy report of ASAP and/or HGPIN may be timely.AimsWe investigated the implications of a diagnosis of atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) on prostate biopsy.MethodsThe rate of re-biopsy and the incidence of carcinoma on repeat biopsy for benign, HGPIN, and ASAP groups were compared. Mean PSA and PSA velocity was also compared between groups.ResultsThere was an increased risk of developing prostate cancer in the foll...
Source: Irish Journal of Medical Science - November 19, 2021 Category: General Medicine Source Type: research

Personal perception of risk and melanoma awareness in an Irish cohort
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 18, 2021 Category: General Medicine Source Type: research

Up-regulation of TGFBI and TGFB2 in the plasma of gestational diabetes mellitus patients and its clinical significance
ConclusionsTGFBI and TGFB2 were up-regulated in the placenta and plasma of GDM patients, and TGFBI and TGFB2 in the plasma are potent to be diagnostic markers for the GDM. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 18, 2021 Category: General Medicine Source Type: research

Correction to: Paediatric major trauma: demographics, management and outcomes at Cork University Hospital
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 18, 2021 Category: General Medicine Source Type: research

Artificial Intelligence: the future of medicine, or an overhyped and dangerous idea?
ConclusionThis report concludes that balanced assessment of AI ’s role in healthcare requires improvement in three areas: improving clarity in definition of AI and its extant remit in medicine; aligning contemporary discourse on AI use with contemporary objective ethical, legal and system frameworks; and clearly identifying for dismissal a number of logical f allacies deliberately sensationalising AI’s potential. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 16, 2021 Category: General Medicine Source Type: research

The effect of pterygium surgery on intraocular lens power and ocular biometric parameters
ConclusionsPterygium surgery causes a significant decrease in calculated IOL power obtained with all formulas. It becomes more pronounced with the increase in the size of the pterygium. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 13, 2021 Category: General Medicine Source Type: research

Letter to the editor regarding penicillin allergy de-labelling in Ireland
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 12, 2021 Category: General Medicine Source Type: research

Comparative efficacy of 0.2% chlorhexidine and 10% Betadine for perioral skin disinfection prior to oral surgical procedures: a clinical trial
This study aimed to compare the efficacy of 0.2% chlorhexidine (CHX) and 10% Betadine (povidone-iodine) for perioral skin disinfection prior to oral surgical procedures.MethodsThis clinical trial (IRCT20181017041365N1) (registration date: 2019/05/04) evaluated 57 male patients who were randomly selected among those presenting to the Periodontology Department of Ahvaz Jundishapur University. Baseline microbial samples were collected from the perioral skin at the right and left sides of the face in each patient by sterile swabs. Next, the perioral area was disinfected with 10% Betadine in the right side and 0.2% CHX in the l...
Source: Irish Journal of Medical Science - November 12, 2021 Category: General Medicine Source Type: research

Orbital involvement in Waldenstrom macroglobulinaemia: a multidisciplinary approach
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 11, 2021 Category: General Medicine Source Type: research

Association between sleep quality and general anesthesia in teenager under elective surgery: a prospective study
ConclusionsTeenagers who were treated with general anesthesia and under urologic or otolaryngologic surgery might have poor sleep quality within 7 postoperative days. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 10, 2021 Category: General Medicine Source Type: research

Correction to: Virtual fracture clinic reduces patient X ‑ray volume for common wrist and ankle fractures
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 9, 2021 Category: General Medicine Source Type: research

Experiences and priorities of older adults during the COVID-19 pandemic
ConclusionsAdverse consequences of ‘cocooning’ were commonly expressed amongst older adults. Public health policy should take into account the heterogeneity of this population and be sensitive to their self-expressed wishes and priorities. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 8, 2021 Category: General Medicine Source Type: research

Respiratory muscle strength in volleyball players suffered from COVID-19
ConclusionsInspiratory and expiratory muscle strength in COVID-19 players were more affected compared with non-COVID-19 players. Pulmonary functions were mostly preserved in COVID-19 players. Respiratory muscle weakening can affect the performance of female players. Therefore, respiratory muscle strength training could be suggested in female players with COVID-19 to increase respiratory muscle strength and prevent deterioration in performance.Trial registration (ClinicalTrials.gov)Registration ID: NCT04789512. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 8, 2021 Category: General Medicine Source Type: research

Cardiovascular autonomic responses during head-up tilt test in newly diagnosed type 2 diabetes
AbstractBackgroundAutonomic dysfunction is commonly observed in patients with long-standing type 2 diabetes. Previous studies have confirmed the value of both subjectively assessed symptoms and objective measurements of autonomic nervous system function in diagnosing cardiovascular autonomic neuropathy. However, the head-up tilt test (HUTT) has been rarely used to investigate cardiovascular autonomic responses in subjects with high risk of  newly diagnosed type 2 diabetes (nT2D).ObjectiveTo evaluate autonomic cardiovascular responses through passive orthostatic challenge along the diabetes continuum.MethodsThe study p...
Source: Irish Journal of Medical Science - November 8, 2021 Category: General Medicine Source Type: research

Paediatric major trauma: demographics, management and outcomes at Cork University Hospital
AbstractObjectivesTo establish the demographics, injury patterns, management and outcomes of paediatric major trauma patients at Cork University Hospital (CUH).MethodsThis was a retrospective, descriptive study. Data from all CUH paediatric major trauma cases that were recorded in the Trauma Audit and Research Network (TARN) database from January 2014 to July 2018 were examined. All patients were under the age of sixteen and fulfilled NOCA ’s Major Trauma Audit inclusion criteria (Appendix).ResultsA total of 163 patients were included, with a mean age of 9  years (standard deviation 4.8 years); 33% (n&thins...
Source: Irish Journal of Medical Science - November 6, 2021 Category: General Medicine Source Type: research

The expression and clinical significance of ER β/ERα in ovarian cancer: can we predict the effectiveness of platinum plus taxane therapy?
ConclusionA high level of ER β and not ERα expression can predict the efficacy of front-line platinum plus taxane chemotherapy in stage III HGSOC patients. The status of estrogen receptor beta can be considered as one of the possible predictors for evaluating the effectiveness of ovarian cancer therapy. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 6, 2021 Category: General Medicine Source Type: research

Dietary supplements, cytochrome metabolism, and pharmacogenetic considerations
ConclusionCYP P450 activity is an important consideration for any patient but becomes increasingly critical if patients have certain CYP P450 phenotypes that impact metabolism. These popular supplements have the potential for changes in supplement exposure, and adverse effects based on pharmacogenetic profiles. Furthermore, these sites of metabolism are shared with many medications, setting the stage for possibly more profound interactions between medications and supplements. This paper highlights the mechanisms in which dietary supplements may constitute a risk for patients with certain CYP P450 phenotypes. Further resear...
Source: Irish Journal of Medical Science - November 4, 2021 Category: General Medicine Source Type: research

Real-life experience: sensitivity and specificity of nasal and saliva samples for COVID-19 diagnosis
ConclusionsThe sample taken by the paramedic was compatible compared to the real-life experience for the samples taken by the patient in the COVID-19 pandemic period. During the pandemic that is unknown when it will end, this study demonstrated that taking the sample of the patient alone for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test is a beneficial approach to the protection of the healthcare worker, reducing the need for protective equipment, increasing the patient ’s comfort and rapid sampling. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 3, 2021 Category: General Medicine Source Type: research

Oral N-acetylcysteine as an adjunct to standard medical therapy improved heart function in cases with stable class II and III systolic heart failure
ConclusionsThese preliminary data support experimental findings showing that NAC supplementation is able to improve heart function.Trial registrationThe registration of the trial was done at the Iranian Registry of Clinical Trials (www.irct.ir). Identifier code: IRCT20120215009014N333. Registration date: 2020 –01-11. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 2, 2021 Category: General Medicine Source Type: research

Gone in 60  days: our first experience with a bioconvertible IVC filter
We describe our first deployment of the filter in an 85-year-old female with gastric malignancy (who subsequently underwent a subtotal gastrectomy) with a history of anaemia and previous pulmonary emboli. The availability of a bioconvertible filter constitutes a further step forward in the management of patients with potential or active thromboembolic disease. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 2, 2021 Category: General Medicine Source Type: research

Repair of sternoclavicular joint ligament: a novel approach
ConclusionsWe believe this novel technique is safer than the existing described techniques, and it does not compromise on functional outcomes. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - November 1, 2021 Category: General Medicine Source Type: research

COVID-19 vaccine — can it affect fertility?
AbstractHeadlines have appeared across multiple social media platforms questioning the effects of newly authorised COVID-19 vaccines on fertility. Although the effects on future fertility were not studied in the initial trials, at present, there is no evidence that the COVID-19 vaccine has any effect of future fertility. It is well known that pregnant women are at a higher risk of complications associated with COVID-19 such as ICU admission and death, and there is a rare but tragic increase in placentitis and stillbirth, highlighting the importance for those planning a pregnancy any time in the future to be vaccinated. Her...
Source: Irish Journal of Medical Science - October 15, 2021 Category: General Medicine Source Type: research

Genetic association between CDKN2B-AS1 polymorphisms and the susceptibility of primary open-angle glaucoma (POAG): a meta-analysis from 21,775 subjects
This study aimed to evaluate the correlation of CDKN2B-AS1 polymorphisms and POAG susceptibility using a meta-analysis.MethodsMeta-analysis was performed by searching PubMed, Web of science, the Cochrane database of system reviews, CNKI, and Embase databases. The relationship of CDKN2B-AS1 rs4977756, rs10120688, rs2157719, and rs7049105 polymorphisms and POAG risk was evaluated by the odds ratios (ORs) and 95% confidence intervals (CIs).ResultsEleven studies with 8290 cases and 13,485 controls were included in the present meta-analysis. The alleles of rs4977756 and rs10120688 significantly increased the risk of POAG (rs497...
Source: Irish Journal of Medical Science - October 14, 2021 Category: General Medicine Source Type: research

Pre-vaccination immune response to COVID-19 in a population in Northeast Portugal
ConclusionIgM and IgG displayed a similar initial increase (within 1/2  weeks), with IgG having a significant decrease after the 21st week post-diagnosis, translating a loss of immunity at this point. The youngest and oldest symptomatic age groups were found to be the highest responders. Antibody assays enabled the identification of previously undiagnosed participants . (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 12, 2021 Category: General Medicine Source Type: research

Unclear reporting of secondary outcome in randomized trial of Lv et al
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 12, 2021 Category: General Medicine Source Type: research

Relation among EGFL7, ITGB3, and KLF2 and their clinical implication in multiple myeloma patients: a prospective study
ConclusionEGFL7, ITGB3, and KLF2 may serve as potential prognostic indicators in MM patients. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 11, 2021 Category: General Medicine Source Type: research

Correction to: Predictors of improvement in resting heart rate after exercise training in patients with chronic obstructive pulmonary disease
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 11, 2021 Category: General Medicine Source Type: research

Burnout on the frontline: the impact of COVID-19 on emergency department staff wellbeing
ConclusionsThe COVID-19 pandemic may be contributing to the long-established problem of health care burnout. The trajectory of this disease is still unclear. Consistent, progressive measures to address staff well-being, and support frontline workers, are imperative going forward. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 9, 2021 Category: General Medicine Source Type: research

Transition to telehealth
AbstractIn recent years, telemedicine has been increasingly incorporated into medical practice, a process which has now been accelerated by the COVID-19 pandemic. As telemedicine continues to progress, it is necessary for medical institutions to incorporate telemedicine into their curricula, and to provide students with the necessary skills and experience to effectively carry out telemedicine consultations. The purposes of this study are to review the involvement of medical students with telemedicine and to determine both the benefits and the challenges experienced. A literature review on the MEDLINE; CINAHL Plus; APA Psyc...
Source: Irish Journal of Medical Science - October 9, 2021 Category: General Medicine Source Type: research

Long non-coding RNA Plasmacytoma variant 1 in acute ischemic stroke: association with disease risk, severity, and recurrence-free survival and relation with inflammatory cytokines
AbstractObjectiveLong non-coding RNA plasmacytoma variant 1 (Lnc-PVT1) is implied with neuron apoptosis, inflammatory cytokines recruitment, endothelial cell proliferation, and angiogenesis; the latter are closely implicated in acute ischemic stroke (AIS) pathology. However, clinical significance of Lnc-PVT1 in AIS management remains unexplored. Thus, this study aimed to investigate this topic.MethodsIn total, 110 patients AIS and 110 controls were enrolled. Peripheral blood mononuclear cells (PBMCs) and serum were extracted from AIS patients and controls. Then, RT-qPCR was performed to determine the PBMC Lnc-PVT1 expressi...
Source: Irish Journal of Medical Science - October 7, 2021 Category: General Medicine Source Type: research

Ascaris lumbricoides and the surgical complications: our experience from Medical College Hospital
ConclusionAscaris lumbricoides is common cause of acute abdomen in our valley attributed to poor hygiene and low socioeconomic background. In patients of high clinical suspicion of worm obstruction, prompt investigations should be advised to reach a definitive diagnosis and prevent the development of complications. Significant efforts must be channelised at political and society levels for the prevention of this disease. Mass deworming programs should be adopted to overcome this menace. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 7, 2021 Category: General Medicine Source Type: research

COVID-19 outbreak impact on emergency trauma visits and trauma surgery in a level 3 trauma center
ConclusionDespite the decrease in the visit frequency of adult trauma patients during the pandemic period, the needs for trauma surgery, ICU, and ward admission did not change. Trauma teams should continue their duties during the pandemic period. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 7, 2021 Category: General Medicine Source Type: research

Ubi pus, ibi evacua: a review of 601 peritonsillar abscess adult cases
ConclusionΟver 10% of PTA cases may develop complications, the most common of which is extension into deep neck spaces. Comorbid conditions increase the risk of complications. Despite the wide range of treatment strategies, incision and drainage remain the cornerstone of surgical treatment. In patients with no comorbidities, intravenous antibiotics appear to have no advantage over oral antibiotics. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 6, 2021 Category: General Medicine Source Type: research

The effect of exercise on disease-free survival and overall survival in patients with breast cancer
ConclusionExercise was associated with decreased relapse and mortality rates in patients with BC. Therefore, exercise should be recommended to BC patients as a significant component of the treatment. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 4, 2021 Category: General Medicine Source Type: research

Estimating need for alcohol treatment in Ireland using national treatment surveillance data
ConclusionsDespite high rates of alcohol consumption and dependence, the rate of treatment entry nationally is sub-optimal, although there are wide geographic variations. There is a need to better understand the reasons for low treatment entry rates in Ireland for people with alcohol dependence. Monitoring and surveillance play a key role in measuring the successful efforts to reduce the harm of alcohol. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 3, 2021 Category: General Medicine Source Type: research

Correction to: The effect of video exercise ‑based telerehabilitation on clinical outcomes, expectation, satisfaction, and motivation in patients with chronic low back pain
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 2, 2021 Category: General Medicine Source Type: research

General data protection regulations (2018) and clinical research: perspectives of patients and doctors in an Irish university teaching hospital
AbstractBackgroundEurope ’s General Data Protection Regulation, or GDPR, is a set of data protection rules on the acquisition, storage, use, and access of personal data. GDPR came into effect in May 2018 when it was introduced across all 27 European Union (EU) member states and the European Economic Area (EEA). Maintainin g compliance with this legislation has presented significant new challenges for ongoing clinical research.AimsTo evaluate the knowledge and expectations of patients and doctors regarding GDPR and implications for future clinical research.MethodsAn anonymous 12-item questionnaire was circulated to pa...
Source: Irish Journal of Medical Science - September 30, 2021 Category: General Medicine Source Type: research

Systematic review of latent tuberculosis infection research to inform programmatic management in Ireland
AbstractThe World Health Organisation (WHO) End Tuberculosis (TB) Strategy and the WHO Framework Towards Tuberculosis Elimination in Low Incidence Countries state that latent tuberculosis infection (LTBI) screening and treatment in selected high-risk groups is a priority action to eliminate TB. The European Centre for Disease Prevention and  Control (ECDC) advises that this should be done through high-quality programmatic management, which they describe as having six key components. The research aim was to systematically review the literature to identify what is known about the epidemiology of LTBI and the uptake and ...
Source: Irish Journal of Medical Science - September 30, 2021 Category: General Medicine Source Type: research

There is an association between gastro-oesophageal reflux and cow ’s milk protein intolerance
ConclusionThis review highlights an association between GOR and CMPI. CMPI should be considered, particularly in cases of reflux resistant to pharmacological therapy, as a co-existing or causative entity accounting for symptoms. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 30, 2021 Category: General Medicine Source Type: research

JKAP, Th1 cells, and Th17 cells are dysregulated and inter-correlated, among them JKAP and Th17 cells relate to cognitive impairment progression in Alzheimer ’s disease patients
This study aimed to investigate its clinical value serving as a biomarker for AD.MethodsFifty AD patients, 50 Parkinson ’s disease (PD) patients, and 50 controls (patients with non-degenerative neurological diseases with normal cognition) were enrolled. Their β-protein 42 (Aβ42), total tau (t-tau), p-tau, and Mini-Mental State Examination (MMSE) scale were assessed. Furthermore, JKAP in serum and T-help type 1 (T h1) and T-help type 17 (Th17) cells in CD4+ T cells were measured.ResultsJKAP level was lower, while Th17 cell proportion (but not Th1 cell proportion) was higher in AD patients compared with PD pa...
Source: Irish Journal of Medical Science - September 30, 2021 Category: General Medicine Source Type: research

The expression and clinical significance of GPR39 in colon cancer
ConclusionsGPR39 was upregulated in colon cancer tissues compared with tumor-adjacent tissues. GPR39 was an independent prognostic biomarker in colon cancer for poor prognosis. EPCAM and PD-L1 were substantially associated with GPR39 expression, and they were also identified as prognostic biomarkers in colon cancers. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 29, 2021 Category: General Medicine Source Type: research