Ureter and Renal Pelvis Cancer Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

CD226 promotes renal fibrosis by regulating macrophage activation and migration
J Leukoc Biol. 2024 Apr 25:qiae054. doi: 10.1093/jleuko/qiae054. Online ahead of print.ABSTRACTIt has been found that CD226 plays an important role in regulating macrophage function, but its expression and function in macrophages during renal fibrogenesis have not been studied. Our data demonstrated that CD226 expression in macrophages was obviously upregulated in the unilateral ureteral obstruction model, while CD226 deficiency attenuated collagen deposition in renal interstitium along with fewer M1 within renal cortex and renal medulla and a lower level of proinflammatory factors compared to that of control littermates. ...
Source: Journal of Leukocyte Biology - April 25, 2024 Category: Hematology Authors: Yun Song Yazhen Wang Juan Li Yuting Shen Yongli Hou Zhaoyue Fu Liang Fang Boquan Jin Lihua Chen Source Type: research

Predictive role of ureteral wall thickness and patient characteristics in endoscopic treatment outcomes for ureteral stricture disease following stone surgery
ConclusionsOur current results indicated that assessment of UWT value at the obstructing stone could be helpful enough to predict the likelihood of failure following endoscopic management of strictures with high sensitivity and specificity. Evaluation of this particular parameter could let the endourologists to look for more rational treatment alternatives with necessary measures taken on time. (Source: World Journal of Urology)
Source: World Journal of Urology - April 25, 2024 Category: Urology & Nephrology Source Type: research

Evaluation of the effect of 9.5/11.5-fr ureteral access sheath use on acute kidney injury with the myo-inositol oxygenase biomarker in patients undergoing retrograde intrarenal surgery: a prospective, randomized, and controlled study
CONCLUSION: Even if UAS is not used, significant acute kidney injury is not observed under gravity irrigation and therefore, if we avoid manual pumping, the intrarenal pressure remains low, thus potentially rendering the use of 9,5/11,5-Fr UAS unnecessary.PMID:38651905 | DOI:10.1080/13645706.2024.2340730 (Source: Minimally Invasive Therapy and Allied Technologies)
Source: Minimally Invasive Therapy and Allied Technologies - April 23, 2024 Category: Surgery Authors: Abdullah Turan Erkan Hirik Abdullah Erdo ğan Abdulsemet Altun Cuma Merto ğlu Emre Şam Muhittin Atar Source Type: research

Urgent ureterorenoscopy as a primary treatment for ureteral stone: why not?
AbstractTo evaluate the feasibility of urgent ureteroscopy (uURS) and elective ureteroscopy (eURS) in the management of patients with renal colic due to ureteral stones. Patients who were operated for ureteral stones between September 2020 and March 2022 were determined retrospectively. The patients who were operated within the first 24 h constituted the uURS group, while the patients who were operated after 24 h were classified as eURS. No limiting factors such as age, gender and concomitant disease were determined as inclusion criteria. Patients with bilateral or multiple ureteral stones, bleeding diathesis, patients ...
Source: Urolithiasis - April 23, 2024 Category: Urology & Nephrology Source Type: research

Long Term Renal Preservation and Complication Profile with Ileal Ureter Creation
To examine long-term ileal ureter replacement results at over 32 years at our institution. Long segment or proximal ureteral strictures pose a challenging reconstructive problem. Ureteroureterostomy, psoas hitch, boari flap, buccal ureteroplasty and autotransplantation are common reconstructive techniques. We show that ileal ureter remains a lasting option. (Source: Urology)
Source: Urology - April 22, 2024 Category: Urology & Nephrology Authors: Mary E. Soyster, Ramzy T. Burns, James E. Slaven, Jason L. Zappia, Peter J. Arnold, Joshua D. Roth, Richard Bihrle, M. Francesca Monn, Matthew J. Mellon Source Type: research

Renal pelvic plasmacytoid subtype urothelial carcinoma accompanied with solitary mammary metastasis
AbstractA 72-year-old female was referred to our institution for further evaluation of right renal tumor detected during work-up for macroscopic hematuria in other hospital. CT urography performed at our institution suggested renal pelvic tumor. Voiding cytology was atypical. CT also revealed a small mass in the right mammary gland. Percutaneous needle biopsies were performed on the right mammary gland and renal mass, leading to a pathological diagnosis of UC with plasmacytoid subtype, suggesting metastasis from the renal pelvic UC to the mammary gland. She had a favorable response to four cycles of dose-dense MVAC therapy...
Source: International Cancer Conference Journal - April 22, 2024 Category: Cancer & Oncology Source Type: research

Antisense oligonucleotide-mediated terminal intron retention of endoglin: A potential strategy to inhibit renal interstitial fibrosis
Biochim Biophys Acta Mol Basis Dis. 2024 Apr 18;1870(5):167186. doi: 10.1016/j.bbadis.2024.167186. Online ahead of print.ABSTRACTTGF-β is considered an important cytokine in the development of interstitial fibrosis in chronic kidney disease. The TGF-β co-receptor endoglin (ENG) tends to be upregulated in kidney fibrosis. ENG has two membrane bound isoforms generated via alternative splicing. Long-ENG was shown to enhance the extent of renal fibrosis in an unilateral ureteral obstruction mouse model, while short-ENG inhibited renal fibrosis. Here we aimed to achieve terminal intron retention of endoglin using antisense-ol...
Source: Biochimica et Biophysica Acta - April 20, 2024 Category: Biochemistry Authors: Tessa Gerrits Kyra L Dijkstra Jan Anthonie Bruijn Marion Scharpfenecker Roel Bijkerk Hans J Baelde Source Type: research

A comparison between vapor tunnel and virtual basket for the treatment of proximal ureteral stones using holmium:YAG laser (Cyber Ho): which is the best tool to reduce retropulsion?
ConclusionsVT and VB are equally safe and effective tools in reducing retropulsion of ureteral stones. Operative time, dusting time and SFR were comparable. They also equally avoided stone push-up and prevented ureteral lesions, which may later occur in ureteral strictures. (Source: World Journal of Urology)
Source: World Journal of Urology - April 20, 2024 Category: Urology & Nephrology Source Type: research

Metastasis to the bladder from primary breast cancer: A case report and literature review
Oncol Lett. 2024 Apr 5;27(6):249. doi: 10.3892/ol.2024.14382. eCollection 2024 Jun.ABSTRACTBreast cancer is the most prevalent malignant tumor affecting women and represents the leading cause of female cancer-related mortality worldwide. Although distant organ metastasis accounts for the majority of breast cancer-related deaths, reports on bladder metastasis are limited in the existing literature. The present study describes the case of a patient with bladder metastasis originating from breast cancer. In addition, the present study also provides a review of 54 cases of similar disease that have been documented in the curre...
Source: Oncology Letters - April 19, 2024 Category: Cancer & Oncology Authors: Hanli Zhou Danna Liu Lu Chen Yujie Zhang Xiaoli Zhao Yongchao Ge Mengmeng Liu Tiandong Kong Source Type: research

GSE199178 Tight Junction Claudins-associated vascular heterogeneity determines organotypic metastasis
Contributors : Valerie LeBleu ; Toru MiyakeSeries Type : Expression profiling by arrayOrganism : Mus musculusTo identify the underlying mechanisms associated with lung and kidney fibrosis inducing lung metastasis, we evaluated global transcriptomic changes in healthy lung, fibrotic lung fibrosis, and lung from mice with kidney fibrosis.Results provide information on the vascular remodeling of the lungs with organ fibrosis. Lung fibrosis is induced with intratracheal bleomycin administration. Kidney fibrosis is induced by unilateral ureter obstruction (UUO). (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - April 19, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research

Recent developments in ureteral stent: Substrate material, coating polymer and technology, therapeutic function
Colloids Surf B Biointerfaces. 2024 Apr 12;238:113916. doi: 10.1016/j.colsurfb.2024.113916. Online ahead of print.ABSTRACTThe ureteral stent is an effective treatment for clinical ureteral stricture following urological surgery, and the functional coating of the stent could effectively inhibit bacterial colonization and other complications. The present review provides an analysis and description of the materials used in ureteral stents and their coatings. Emphasis is placed on the technological advancements of functional coatings, taking into consideration the characteristics of these materials and the properties of their ...
Source: Colloids and Surfaces - April 18, 2024 Category: Biotechnology Authors: Kai-Chao Wen Zheng-An Li Ji-Heng Liu Chuan Zhang Feng Zhang Feng-Qian Li Source Type: research

Gene of the month: the uroplakins
Uroplakins are a family of membrane-spanning proteins highly specific to the urothelium. There are four uroplakin proteins in humans. These are encoded by the following UPK genes: UPK1A, UPK1B, UPK2 and UPK3. Uroplakin proteins span the apical membrane of umbrella cells of the urothelium, where they associate into urothelial plaques. This provides a barrier function to prevent passage of urine across the urothelium in the renal pelvis, ureters, and bladder. Uroplakins are also involved in developmental processes such as nephrogenesis. The specific localisation of uroplakins within the urothelium means that they are often e...
Source: Journal of Clinical Pathology - April 18, 2024 Category: Pathology Authors: Sivakumaar, K., Griffin, J., Schofield, E., Catto, J. W. F., Jubber, I. Tags: Gene of the month Source Type: research

Exploring the Topography of the Obturator Artery and Corona Mortis: a Detailed Analysis with Surgical Implications
ConclusionsOur study developed a unique arterial anatomical map of the ObA, showcasing its origin and course. Moreover, we have provided more data for straightforward intraoperative identification of the corona mortis through simple anatomical landmarks, including the pubic symphysis. Interestingly, a statistically significant difference (p < 0.05) between the morphometric properties of the aberrant ObAs and the “normal” ObAs originating from the internal iliac artery was found. It is hoped that our study may aid in reducing the risk of serious hemorrhagic complications during various surgical procedures in the...
Source: International Urogynecology Journal and Pelvic Floor Dysfunction - April 18, 2024 Category: OBGYN Source Type: research