Ureter and Renal Pelvis Cancer Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

GSE199178 Tight Junction Claudins-associated vascular heterogeneity determines organotypic metastasis
Contributors : Valerie LeBleu ; Toru MiyakeSeries Type : Expression profiling by arrayOrganism : Mus musculusTo identify the underlying mechanisms associated with lung and kidney fibrosis inducing lung metastasis, we evaluated global transcriptomic changes in healthy lung, fibrotic lung fibrosis, and lung from mice with kidney fibrosis.Results provide information on the vascular remodeling of the lungs with organ fibrosis. Lung fibrosis is induced with intratracheal bleomycin administration. Kidney fibrosis is induced by unilateral ureter obstruction (UUO). (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - April 19, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research

Recent developments in ureteral stent: Substrate material, coating polymer and technology, therapeutic function
Colloids Surf B Biointerfaces. 2024 Apr 12;238:113916. doi: 10.1016/j.colsurfb.2024.113916. Online ahead of print.ABSTRACTThe ureteral stent is an effective treatment for clinical ureteral stricture following urological surgery, and the functional coating of the stent could effectively inhibit bacterial colonization and other complications. The present review provides an analysis and description of the materials used in ureteral stents and their coatings. Emphasis is placed on the technological advancements of functional coatings, taking into consideration the characteristics of these materials and the properties of their ...
Source: Colloids and Surfaces - April 18, 2024 Category: Biotechnology Authors: Kai-Chao Wen Zheng-An Li Ji-Heng Liu Chuan Zhang Feng Zhang Feng-Qian Li Source Type: research

Gene of the month: the uroplakins
Uroplakins are a family of membrane-spanning proteins highly specific to the urothelium. There are four uroplakin proteins in humans. These are encoded by the following UPK genes: UPK1A, UPK1B, UPK2 and UPK3. Uroplakin proteins span the apical membrane of umbrella cells of the urothelium, where they associate into urothelial plaques. This provides a barrier function to prevent passage of urine across the urothelium in the renal pelvis, ureters, and bladder. Uroplakins are also involved in developmental processes such as nephrogenesis. The specific localisation of uroplakins within the urothelium means that they are often e...
Source: Journal of Clinical Pathology - April 18, 2024 Category: Pathology Authors: Sivakumaar, K., Griffin, J., Schofield, E., Catto, J. W. F., Jubber, I. Tags: Gene of the month Source Type: research

Exploring the Topography of the Obturator Artery and Corona Mortis: a Detailed Analysis with Surgical Implications
ConclusionsOur study developed a unique arterial anatomical map of the ObA, showcasing its origin and course. Moreover, we have provided more data for straightforward intraoperative identification of the corona mortis through simple anatomical landmarks, including the pubic symphysis. Interestingly, a statistically significant difference (p < 0.05) between the morphometric properties of the aberrant ObAs and the “normal” ObAs originating from the internal iliac artery was found. It is hoped that our study may aid in reducing the risk of serious hemorrhagic complications during various surgical procedures in the...
Source: International Urogynecology Journal and Pelvic Floor Dysfunction - April 18, 2024 Category: OBGYN Source Type: research

Distal renal tubular acidosis as a rare complication of vesicoureteral reflux in children: a case report and literature review
In conclusion, the development of hypokalemia and nephrolithiasis/nephrocalcinosis along with metabolic acidosis in a patient diagnosed with VUR should be considered as an indicator of impaired tubular functions. Also, the possibility of an underlying VUR in the p resence of recurrent urinary tract infection in a patient diagnosed with dRTA should not be ignored. (Source: CEN Case Reports)
Source: CEN Case Reports - April 18, 2024 Category: Urology & Nephrology Source Type: research

Multicenter evaluation of complex urinary diversion for renal transplantation: outcomes of complex surgical solutions
ConclusionThe mid-term kidney transplant function with complex urinary diversion appears to be comparable to transplants with regular urinary diversions. Hence, complex urinary diversion should always be considered as a surgical option, even during transplantation, if necessary. (Source: World Journal of Urology)
Source: World Journal of Urology - April 17, 2024 Category: Urology & Nephrology Source Type: research

Fluid dynamics within renal cavities during endoscopic stone surgery: does the position of the flexible ureteroscope and ureteral access sheath affect the outflow rate?
ConclusionsOur study showed that higher fluid outflow rates are observed from upper and middle calyces compared to lower calyx. This was true when the UAS was positioned 2 cm below the PUJ and at the iliac crest. Significant worsening of fluid dynamics from upper and middle calyces was observed when the UAS was placed distally at the level of the iliac crest. While the difference was statistically significant, the absolute change was not significant. In contrast, f or lower calyces, a statistically significant improvement was documented. (Source: World Journal of Urology)
Source: World Journal of Urology - April 17, 2024 Category: Urology & Nephrology Source Type: research

Prone vs supine percutaneous nephrolithotomy: does position affect renal pelvic pressures?
AbstractThe purpose of this study was to measure and compare renal pelvic pressure (RPP) between prone and supine percutaneous nephrolithotomy (PCNL) in a benchtop model. Six identical silicone kidney models were placed into anatomically correct prone or supine torsos constructed from patient CT scans in the corresponding positions. A 30-Fr renal access sheath was placed in either the upper, middle, or lower pole calyx for both prone and supine positions. Two 9-mm BegoStones were placed in the respective calyx and RPPs were measured at baseline, irrigating with a rigid nephroscope, and irrigating with a flexible nephroscop...
Source: Urolithiasis - April 17, 2024 Category: Urology & Nephrology Source Type: research

Extracorporeal shock wave lithotripsy: retrospective study on possible predictors of treatment success and revisiting the role of non-contrast-enhanced computer tomography in kidney and ureteral stone disease
This study aimed to assess the influence of stone size, location, stone density, and skin-to-stone distance (SSD), on the outcome of ESWL. We assessed whether pre-treatment non-contrast-enhanced CT scan (NCCT) confers significant advantages compared to kidney-ureter-bladder film (KUB) only. We reviewed the medical records of 307 cases (165 men, 142 women) with renal and ureteral stones treated consecutively at our institution with ESWL between 2020 and 2023. 44 of these underwent a NCCT. The outcome of ESWL was defined in two ways: visible stone fragmentation on KUB, and the need for further treatment. Overall success of f...
Source: Urolithiasis - April 17, 2024 Category: Urology & Nephrology Source Type: research

Spontaneous Ureteral Rupture During a < sup > 99m < /sup > Tc-Mercaptoacetyltriglycine Renal Scan
J Nucl Med Technol. 2024 Apr 16:jnmt.124.267428. doi: 10.2967/jnmt.124.267428. Online ahead of print.ABSTRACTAfter therapeutic pelvic radiation for malignancy such as prostate cancer, patients are at greater risk for spontaneous ureteral rupture. Bladder outlet obstruction and other more proximal causes of obstruction also exacerbate this vulnerability. Here we present a case of spontaneous ureteral rupture during a 99mTc-mercaptoacetyltriglycine nuclear renal scan secondary to Foley catheter obstruction in a 73-y-old man with a prior ureteral reimplantation procedure. Prompt detection of Foley catheter malfunction could p...
Source: Journal of Nuclear Medicine Technology - April 16, 2024 Category: Nuclear Medicine Authors: Roxana Apostol Paul Rodrigue Source Type: research