Factors affecting the intraoperative calculi excretion during flexible ureteroscopy lithotripsy: an in vitro analysis
ConclusionEmploying negative-pressure UAS, smaller RESD, milder hydronephrosis, lateral position, and smaller gravel size contribute to improved ICE during fURL. Among them, the adoption of negative-pressure UAS had the most substantial effects. (Source: World Journal of Urology)
Source: World Journal of Urology - March 9, 2024 Category: Urology & Nephrology Source Type: research

RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis
Transl Res. 2024 Mar 5:S1931-5244(24)00047-1. doi: 10.1016/j.trsl.2024.03.003. Online ahead of print.ABSTRACTThe progression of chronic kidney disease (CKD) often involves renal interstitial fibrosis (RIF) and subsequent loss of peritubular capillaries (PTCs), which enhances disease severity. Despite advancements in our understanding of fibrosis, effective interventions for reversing capillary loss remain elusive. Notably, RIF exhibits reduced capillary density, whereas renal cell carcinoma (RCC) shows robust angiogenesis under hypoxic conditions. Using RNA sequencing and bioinformatics, we identified differentially expres...
Source: Translational Research : the journal of laboratory and clinical medicine - March 7, 2024 Category: Laboratory Medicine Authors: Yu Zhang Yiqiong Yang Xiuxiu Hu Bizhen Wei Qian Shen Chuanbing Shi Pingsheng Chen Source Type: research

RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis
Transl Res. 2024 Mar 5:S1931-5244(24)00047-1. doi: 10.1016/j.trsl.2024.03.003. Online ahead of print.ABSTRACTThe progression of chronic kidney disease (CKD) often involves renal interstitial fibrosis (RIF) and subsequent loss of peritubular capillaries (PTCs), which enhances disease severity. Despite advancements in our understanding of fibrosis, effective interventions for reversing capillary loss remain elusive. Notably, RIF exhibits reduced capillary density, whereas renal cell carcinoma (RCC) shows robust angiogenesis under hypoxic conditions. Using RNA sequencing and bioinformatics, we identified differentially expres...
Source: Translational Research : the journal of laboratory and clinical medicine - March 7, 2024 Category: Laboratory Medicine Authors: Yu Zhang Yiqiong Yang Xiuxiu Hu Bizhen Wei Qian Shen Chuanbing Shi Pingsheng Chen Source Type: research

RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis
Transl Res. 2024 Mar 5:S1931-5244(24)00047-1. doi: 10.1016/j.trsl.2024.03.003. Online ahead of print.ABSTRACTThe progression of chronic kidney disease (CKD) often involves renal interstitial fibrosis (RIF) and subsequent loss of peritubular capillaries (PTCs), which enhances disease severity. Despite advancements in our understanding of fibrosis, effective interventions for reversing capillary loss remain elusive. Notably, RIF exhibits reduced capillary density, whereas renal cell carcinoma (RCC) shows robust angiogenesis under hypoxic conditions. Using RNA sequencing and bioinformatics, we identified differentially expres...
Source: Translational Research : the journal of laboratory and clinical medicine - March 7, 2024 Category: Laboratory Medicine Authors: Yu Zhang Yiqiong Yang Xiuxiu Hu Bizhen Wei Qian Shen Chuanbing Shi Pingsheng Chen Source Type: research

RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis
Transl Res. 2024 Mar 5:S1931-5244(24)00047-1. doi: 10.1016/j.trsl.2024.03.003. Online ahead of print.ABSTRACTThe progression of chronic kidney disease (CKD) often involves renal interstitial fibrosis (RIF) and subsequent loss of peritubular capillaries (PTCs), which enhances disease severity. Despite advancements in our understanding of fibrosis, effective interventions for reversing capillary loss remain elusive. Notably, RIF exhibits reduced capillary density, whereas renal cell carcinoma (RCC) shows robust angiogenesis under hypoxic conditions. Using RNA sequencing and bioinformatics, we identified differentially expres...
Source: Translational Research : the journal of laboratory and clinical medicine - March 7, 2024 Category: Laboratory Medicine Authors: Yu Zhang Yiqiong Yang Xiuxiu Hu Bizhen Wei Qian Shen Chuanbing Shi Pingsheng Chen Source Type: research