Ureter and Renal Pelvis Cancer Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Exosomes From Human Umbilical Cord Stem Cells Suppress Macrophage-to-myofibroblast Transition, Alleviating Renal Fibrosis
This study investigates their potential to lessen renal fibrosis by targeting macrophage-to-myofibroblast transformation (MMT), a key driver of fibrosis. We employed a mouse model of unilateral ureteral obstruction (UUO) and cultured cells exposed to transforming growth factor-β (TGF-β) to mimic MMT. HucMSC-Exos were administered to UUO mice, and their effects on kidney function and fibrosis were assessed. Additionally, RNA sequencing and cellul ar analysis were performed to elucidate the mechanisms by which HucMSC-Exos inhibit MMT. HucMSC-Exos treatment significantly reduced kidney damage and fibrosis in UUO mice. Th...
Source: Inflammation - April 25, 2024 Category: Allergy & Immunology Source Type: research

Evaluation of the effect of 9.5/11.5-fr ureteral access sheath use on acute kidney injury with the myo-inositol oxygenase biomarker in patients undergoing retrograde intrarenal surgery: a prospective, randomized, and controlled study
CONCLUSION: Even if UAS is not used, significant acute kidney injury is not observed under gravity irrigation and therefore, if we avoid manual pumping, the intrarenal pressure remains low, thus potentially rendering the use of 9,5/11,5-Fr UAS unnecessary.PMID:38651905 | DOI:10.1080/13645706.2024.2340730 (Source: Minimally Invasive Therapy and Allied Technologies)
Source: Minimally Invasive Therapy and Allied Technologies - April 23, 2024 Category: Surgery Authors: Abdullah Turan Erkan Hirik Abdullah Erdo ğan Abdulsemet Altun Cuma Merto ğlu Emre Şam Muhittin Atar Source Type: research

Urgent ureterorenoscopy as a primary treatment for ureteral stone: why not?
AbstractTo evaluate the feasibility of urgent ureteroscopy (uURS) and elective ureteroscopy (eURS) in the management of patients with renal colic due to ureteral stones. Patients who were operated for ureteral stones between September 2020 and March 2022 were determined retrospectively. The patients who were operated within the first 24 h constituted the uURS group, while the patients who were operated after 24 h were classified as eURS. No limiting factors such as age, gender and concomitant disease were determined as inclusion criteria. Patients with bilateral or multiple ureteral stones, bleeding diathesis, patients ...
Source: Urolithiasis - April 23, 2024 Category: Urology & Nephrology Source Type: research

Long Term Renal Preservation and Complication Profile with Ileal Ureter Creation
To examine long-term ileal ureter replacement results at over 32 years at our institution. Long segment or proximal ureteral strictures pose a challenging reconstructive problem. Ureteroureterostomy, psoas hitch, boari flap, buccal ureteroplasty and autotransplantation are common reconstructive techniques. We show that ileal ureter remains a lasting option. (Source: Urology)
Source: Urology - April 22, 2024 Category: Urology & Nephrology Authors: Mary E. Soyster, Ramzy T. Burns, James E. Slaven, Jason L. Zappia, Peter J. Arnold, Joshua D. Roth, Richard Bihrle, M. Francesca Monn, Matthew J. Mellon Source Type: research

Renal pelvic plasmacytoid subtype urothelial carcinoma accompanied with solitary mammary metastasis
AbstractA 72-year-old female was referred to our institution for further evaluation of right renal tumor detected during work-up for macroscopic hematuria in other hospital. CT urography performed at our institution suggested renal pelvic tumor. Voiding cytology was atypical. CT also revealed a small mass in the right mammary gland. Percutaneous needle biopsies were performed on the right mammary gland and renal mass, leading to a pathological diagnosis of UC with plasmacytoid subtype, suggesting metastasis from the renal pelvic UC to the mammary gland. She had a favorable response to four cycles of dose-dense MVAC therapy...
Source: International Cancer Conference Journal - April 22, 2024 Category: Cancer & Oncology Source Type: research

Antisense oligonucleotide-mediated terminal intron retention of endoglin: A potential strategy to inhibit renal interstitial fibrosis
Biochim Biophys Acta Mol Basis Dis. 2024 Apr 18;1870(5):167186. doi: 10.1016/j.bbadis.2024.167186. Online ahead of print.ABSTRACTTGF-β is considered an important cytokine in the development of interstitial fibrosis in chronic kidney disease. The TGF-β co-receptor endoglin (ENG) tends to be upregulated in kidney fibrosis. ENG has two membrane bound isoforms generated via alternative splicing. Long-ENG was shown to enhance the extent of renal fibrosis in an unilateral ureteral obstruction mouse model, while short-ENG inhibited renal fibrosis. Here we aimed to achieve terminal intron retention of endoglin using antisense-ol...
Source: Biochimica et Biophysica Acta - April 20, 2024 Category: Biochemistry Authors: Tessa Gerrits Kyra L Dijkstra Jan Anthonie Bruijn Marion Scharpfenecker Roel Bijkerk Hans J Baelde Source Type: research

A comparison between vapor tunnel and virtual basket for the treatment of proximal ureteral stones using holmium:YAG laser (Cyber Ho): which is the best tool to reduce retropulsion?
ConclusionsVT and VB are equally safe and effective tools in reducing retropulsion of ureteral stones. Operative time, dusting time and SFR were comparable. They also equally avoided stone push-up and prevented ureteral lesions, which may later occur in ureteral strictures. (Source: World Journal of Urology)
Source: World Journal of Urology - April 20, 2024 Category: Urology & Nephrology Source Type: research