Ureter and Renal Pelvis Cancer Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Patients undergoing double J substitution with a pigtail suture stent report a significant decrease of stent-related symptoms. Results from a prospective multicenter longitudinal trial
ConclusionsPatients undergoing DJ substitution with PSS after URS report a significant decrease of SRS. Urologists may consider positioning PSS after URS in pre-stented patients to reduce the impact of SRS. (Source: World Journal of Urology)
Source: World Journal of Urology - March 22, 2024 Category: Urology & Nephrology Source Type: research

Understanding formation processes of calcareous nephrolithiasis in renal interstitium and tubule lumen
J Cell Mol Med. 2024 Apr;28(7):e18235. doi: 10.1111/jcmm.18235.ABSTRACTKidney stone, one of the oldest known diseases, has plagued humans for centuries, consistently imposing a heavy burden on patients and healthcare systems worldwide due to their high incidence and recurrence rates. Advancements in endoscopy, imaging, genetics, molecular biology and bioinformatics have led to a deeper and more comprehensive understanding of the mechanism behind nephrolithiasis. Kidney stone formation is a complex, multi-step and long-term process involving the transformation of stone-forming salts from free ions into asymptomatic or sympt...
Source: J Cell Mol Med - March 21, 2024 Category: Molecular Biology Authors: Caitao Dong Jiawei Zhou Xiaozhe Su Ziqi He Qianlin Song Chao Song Hu Ke Chuan Wang Wenbiao Liao Sixing Yang Source Type: research

Understanding formation processes of calcareous nephrolithiasis in renal interstitium and tubule lumen
J Cell Mol Med. 2024 Apr;28(7):e18235. doi: 10.1111/jcmm.18235.ABSTRACTKidney stone, one of the oldest known diseases, has plagued humans for centuries, consistently imposing a heavy burden on patients and healthcare systems worldwide due to their high incidence and recurrence rates. Advancements in endoscopy, imaging, genetics, molecular biology and bioinformatics have led to a deeper and more comprehensive understanding of the mechanism behind nephrolithiasis. Kidney stone formation is a complex, multi-step and long-term process involving the transformation of stone-forming salts from free ions into asymptomatic or sympt...
Source: Molecular Medicine - March 21, 2024 Category: Molecular Biology Authors: Caitao Dong Jiawei Zhou Xiaozhe Su Ziqi He Qianlin Song Chao Song Hu Ke Chuan Wang Wenbiao Liao Sixing Yang Source Type: research

Surgical considerations during laparoscopic hysterectomy in patients with pelvic kidney
The kidneys are typically located retroperitoneally in the abdomen; however, a pelvic kidney encompasses the anatomical abnormalities that occur when a kidney fails to ascend from the pelvis during embryogenesis. Pelvic kidneys may lead to variations in vascular supply and the ureteral pathway, and therefore, is important to consider in abdominal and pelvic surgery in order to avoid injury. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: M Yuen, A Farrell, E Parent, E Gagliardi Source Type: research

Bladder flap dissection in gynecologic surgery: tips and tricks for success
Laparoscopic gynecologic surgeries are known to have a complication rate of 0.33% for bladder or ureteral injuries. The most common location of injury is on the posterior side of the bladder during vesico-uterine dissection. While injuries are generally noticed at the time of surgery, an unnoticed serosal injury can lead to delayed cystotomy and vesico-vaginal fistula. A safe bladder flap technique is important to prevent complications in both the short and long term. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: C Niino, K Hamilton, R Schneyer, R Meyer, M Siedhoff, K Wright, M Truong Source Type: research

Recurrent ureteral endometriosis
We present a case of a 31-year-old female with recurrent endometriosis after excision 5 years prior. Imaging was consistent with deep infiltrating endometriosis along the pelvic sidewall and this corresponded with surgical findings of a 1cm deep infiltrating endometriosis lesion extrinsic to the left ureter. It is crucial for the gynecologic surgeon to be familiar with ureteral endometriosis, its preferred treatment algorithm, and how to prevent recurrence. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: T Horton, A Carrubba Source Type: research

A novel simulation model for ureteral stent placement
Cystoscopy and ureteral stenting are important skills for trainees in gynecologic and urologic surgery to acquire during their training. Oncological and benign conditions requiring complex pelvic surgery are associated with an increased risk of urinary tract injuries. Therefore, placement of temporary ureteral stents either prophylactically or when a ureteral injury is suspected may be necessary. Advanced gynecology trainees such as fellows in urogynecology, oncology and minimally invasive gynecologic surgery should be well versed in placing temporary ureteral stent to avoid or diagnose a ureteral injury. (Source: American...
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: N Wood, L Cheng, D Volkin, E Tunitsky Source Type: research

Endometriosis of the bladder trigone: a fertility- sparing approach
Endometriosis can affect a variety of organs, including the urinary tract. Involvement of urinary structures occurs in 1-5% of endometriosis cases. Patients with urinary tract endometriosis can present with cyclic urinary frequency, dysuria, hematuria, urgency and pain with bladder distention. This video presents a 35-year-old nulliparous woman with dysmenorrhea, dysuria, urgency and pain with bladder distention. Pelvic MRI demonstrated uterine fibroids and deep infiltrating endometriosis invading the right pelvic sidewall and right bladder base involving the full thickness of the bladder near the right ureterovesical junc...
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: T Muir, R Young, E Lin, J Gahan, K Kho Source Type: research

Ureterolysis for advanced endometriosis: principles and pearls for safe execution
Ureterolysis is typically required during resection of advanced endometriosis to keep the ureters safely distant during the procedure or to resect endometriosis involving the ureter itself. Proper technique is imperative to minimize the risk of ureteral injury. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: R Schneyer, K Hamilton, R Meyer, M Truong, K Wright, M Siedhoff Source Type: research

Prophylactic ureteral stents in complex pelvic surgery and rates of acute kidney injury
Prophylactic Ureteral Catheterization (PUC) is among the adjunctive strategies aimed at preventing intraoperative ureteral injury. It has gained some acceptance as a technique to assist in identifying the ureter during surgery. However, there is ongoing debate regarding the acceptance and application of PUC, as there are mixed reports regarding its advantages, complications, and cost-effectiveness. While certain authors claim reduced rates of intraoperative ureteral injury with PUC, aggregated data has failed to conclusively demonstrate its clinical benefits. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: F Sunez, R Jalloul, H Ayoub, J Ma, R Pham, A Agarwal Source Type: research

Renal pelvis metastasis following surgery for breast angiosarcoma: a case report and literature review
This article reports the medical records of a patient diagnosed with breast angiosarcoma who underwent radical mastectomy and was found to have multiple lung metastases 3 years after surgery and renal pelvic metastasis 4 years after surgery. The patient underwent robot-assisted laparoscopic radical nephroureterectomy and sleeve resection of the intramural segment of the ureter, and postoperative pathology and immunohistochemical staining confirmed the diagnosis of renal pelvic metastasis of breast angiosarcoma. The patient received anlotinib for lung metastases following surgery and was followed up for 4 months after surge...
Source: Frontiers in Oncology - March 21, 2024 Category: Cancer & Oncology Source Type: research

Hypermethylation leads to the loss of HOXA5, resulting in JAG1 expression and NOTCH signaling contributing to kidney fibrosis
Epigenetic regulations, including DNA methylation, are critical to the development and progression of kidney fibrosis, but the underlying mechanisms remain elusive. Here, we show that fibrosis of the mouse kidney was associated with the induction of DNA methyltransferases and increases in global DNA methylation and was alleviated by the DNA methyltransferase inhibitor 5-Aza-2 ’-deoxycytidine (5-Aza). Genome wide analysis demonstrated the hypermethylation of 94 genes in mouse unilateral ureteral obstruction kidneys, which was markedly reduced by 5-Aza. (Source: Kidney International)
Source: Kidney International - March 21, 2024 Category: Urology & Nephrology Authors: Xiao Xiao, Wei Wang, Chunyuan Guo, Jiazhu Wu, Sheng Zhang, Huidong Shi, Sangho Kwon, Jiankang Chen, Zheng Dong Tags: basic research Source Type: research

Genitourinary Fistula: 5 Years ’ Experience of Five Referral Centers in Iran
ConclusionsOur patients with genitourinary fistula had a successful outcome following repair techniques, without any significant morbidity or mortality. (Source: International Urogynecology Journal)
Source: International Urogynecology Journal - March 21, 2024 Category: OBGYN Source Type: research