ELABELA-derived peptide ELA13 attenuates kidney fibrosis by inhibiting the Smad and ERK signaling pathways
In conclusion, ELA13 protected against kidney fibrosis through inhibiting the Smad and ERK signaling pathways and could thus be a promising candidate for anti-renal fibrosis treatment.PMID:38584095 | DOI:10.1631/jzus.B2300033 (Source: J Zhejiang Univ Sci ...)
Source: J Zhejiang Univ Sci ... - April 7, 2024 Category: Science Authors: Zhibin Yan Ying Shi Runling Yang Jijun Xue Caiyun Fu Source Type: research

ELABELA-derived peptide ELA13 attenuates kidney fibrosis by inhibiting the Smad and ERK signaling pathways
In conclusion, ELA13 protected against kidney fibrosis through inhibiting the Smad and ERK signaling pathways and could thus be a promising candidate for anti-renal fibrosis treatment.PMID:38584095 | DOI:10.1631/jzus.B2300033 (Source: J Zhejiang Univ Sci ...)
Source: J Zhejiang Univ Sci ... - April 7, 2024 Category: Science Authors: Zhibin Yan Ying Shi Runling Yang Jijun Xue Caiyun Fu Source Type: research

ELABELA-derived peptide ELA13 attenuates kidney fibrosis by inhibiting the Smad and ERK signaling pathways
In conclusion, ELA13 protected against kidney fibrosis through inhibiting the Smad and ERK signaling pathways and could thus be a promising candidate for anti-renal fibrosis treatment.PMID:38584095 | DOI:10.1631/jzus.B2300033 (Source: J Zhejiang Univ Sci ...)
Source: J Zhejiang Univ Sci ... - April 7, 2024 Category: Science Authors: Zhibin Yan Ying Shi Runling Yang Jijun Xue Caiyun Fu Source Type: research

ELABELA-derived peptide ELA13 attenuates kidney fibrosis by inhibiting the Smad and ERK signaling pathways
In conclusion, ELA13 protected against kidney fibrosis through inhibiting the Smad and ERK signaling pathways and could thus be a promising candidate for anti-renal fibrosis treatment.PMID:38584095 | DOI:10.1631/jzus.B2300033 (Source: J Zhejiang Univ Sci ...)
Source: J Zhejiang Univ Sci ... - April 7, 2024 Category: Science Authors: Zhibin Yan Ying Shi Runling Yang Jijun Xue Caiyun Fu Source Type: research

ELABELA-derived peptide ELA13 attenuates kidney fibrosis by inhibiting the Smad and ERK signaling pathways
In conclusion, ELA13 protected against kidney fibrosis through inhibiting the Smad and ERK signaling pathways and could thus be a promising candidate for anti-renal fibrosis treatment.PMID:38584095 | PMC:PMC11009446 | DOI:10.1631/jzus.B2300033 (Source: J Zhejiang Univ Sci ...)
Source: J Zhejiang Univ Sci ... - April 7, 2024 Category: Science Authors: Zhibin Yan Ying Shi Runling Yang Jijun Xue Caiyun Fu Source Type: research

ELABELA-derived peptide ELA13 attenuates kidney fibrosis by inhibiting the Smad and ERK signaling pathways
In conclusion, ELA13 protected against kidney fibrosis through inhibiting the Smad and ERK signaling pathways and could thus be a promising candidate for anti-renal fibrosis treatment.PMID:38584095 | PMC:PMC11009446 | DOI:10.1631/jzus.B2300033 (Source: J Zhejiang Univ Sci ...)
Source: J Zhejiang Univ Sci ... - April 7, 2024 Category: Science Authors: Zhibin Yan Ying Shi Runling Yang Jijun Xue Caiyun Fu Source Type: research

Extraperitoneal lateral pelvic sidewall excision: a novel rectal-sparing approach for lateral locally recurrent rectal cancer
Updates Surg. 2024 Apr 6. doi: 10.1007/s13304-024-01834-2. Online ahead of print.ABSTRACTLocally recurrent rectal cancer (LRRC) involving the lateral pelvic sidewall requires a complex approach to maximize the likelihood of R0 resection, which is the only predictor of survival. The purpose of this report is to describe a novel technique to resect a localized lateral pelvic sidewall LRRC. A 63-year-old male patient was referred for a 15-mm LRRC near the right internal iliac vessels. Endoscopic ultrasound and magnetic resonance imaging excluded any involvement of the pelvic colon or residual rectum. A combined extraperitonea...
Source: Cancer Control - April 6, 2024 Category: Cancer & Oncology Authors: Luca Sorrentino Gaia Colletti Filiberto Belli Alessandro Gronchi Source Type: research

Extraperitoneal lateral pelvic sidewall excision: a novel rectal-sparing approach for lateral locally recurrent rectal cancer
AbstractLocally recurrent rectal cancer (LRRC) involving the lateral pelvic sidewall requires a complex approach to maximize the likelihood of R0 resection, which is the only predictor of survival. The purpose of this report is to describe a novel technique to resect a localized lateral pelvic sidewall LRRC. A 63-year-old male patient was referred for a 15-mm LRRC near the right internal iliac vessels. Endoscopic ultrasound and magnetic resonance imaging excluded any involvement of the pelvic colon or residual rectum. A combined extraperitoneal antero-lateral approach and gluteal access were used to optimize vascular contr...
Source: Updates in Surgery - April 6, 2024 Category: Surgery Source Type: research

Towards the establishment of national diagnostic reference levels for abdomen, KUB, and lumbar spine x-ray examinations in Sri Lanka: a multi-centric study
Diagnostic reference levels (DRLs) and achievable doses (ADs) provide guidance to optimise radiation doses for patients undergoing medical imaging procedures. This multi-centre study aimed to compare institutional DRLs (IDRLs) across hospitals, propose ADs and multi-centric DRLs (MCDRLs) for four common x-ray examinations in Sri Lanka, and assess the potential for dose reduction. A prospective cross-sectional study of 894 adult patients referred for abdomen anteroposterior (AP), kidney-ureter-bladder (KUB) AP, lumbar spine AP, and lumbar spine lateral (LAT) x-ray examinations was conducted. Patient demographic information ...
Source: Journal of Radiological Protection - April 4, 2024 Category: Physics Authors: Sachith Welarathna, Sivakumar Velautham and Sivananthan Sarasanandarajah Source Type: research

Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence
CONCLUSIONS: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.PMID:38567601 | DOI:10.26355/eurrev_202403_35745 (Source: Cancer Control)
Source: Cancer Control - April 3, 2024 Category: Cancer & Oncology Authors: S-C Jiang Y-G Liao J Luo D Hu Y-D Wang K He Source Type: research

Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence
CONCLUSIONS: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.PMID:38567601 | DOI:10.26355/eurrev_202403_35745 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: S-C Jiang Y-G Liao J Luo D Hu Y-D Wang K He Source Type: research

Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence
CONCLUSIONS: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.PMID:38567601 | DOI:10.26355/eurrev_202403_35745 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: S-C Jiang Y-G Liao J Luo D Hu Y-D Wang K He Source Type: research

Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence
CONCLUSIONS: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.PMID:38567601 | DOI:10.26355/eurrev_202403_35745 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: S-C Jiang Y-G Liao J Luo D Hu Y-D Wang K He Source Type: research

Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence
CONCLUSIONS: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.PMID:38567601 | DOI:10.26355/eurrev_202403_35745 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: S-C Jiang Y-G Liao J Luo D Hu Y-D Wang K He Source Type: research