Which flexible ureteroscope is the best for upper tract urothelial carcinoma treatment?
ConclusionsMiniaturization, digital image caption and image enhancement technologies seem to be the major determinants defining the best flexible ureteroscope for UTUC treatment. The impact of further factors, such as distal tip design, torque, working channel position, risk of contamination, as well as upcoming technological innovations should be evaluated in randomized controlled trials. (Source: World Journal of Urology)
Source: World Journal of Urology - February 15, 2019 Category: Urology & Nephrology Source Type: research

Prognostic significance of BAP1 expression in high-grade upper tract urothelial carcinoma: a multi-institutional study
AbstractPurposeTo evaluate the prognostic value of BRCA1-associated protein-1 (BAP1) expression in upper tract urothelial carcinoma (UTUC), asBAP1 mutations have been associated with prognostic implications in urologic and non-urologic malignancies.MethodsWe reviewed a multi-institutional cohort of patients who underwent radical nephroureterectomy (RNU) for high-grade UTUC from 1990 –2008. Immunohistochemistry (IHC) for BAP1 was performed on tissue microarrays. Staining intensity was graded from 0–3, with BAP1 loss defined as an average intensity of 
Source: World Journal of Urology - February 13, 2019 Category: Urology & Nephrology Source Type: research

Complications related to use of mesh implants in surgical treatment of stress urinary incontinence and pelvic organ prolapse: infection or inflammation?
AbstractThe surgical mesh material used in the surgical treatment of stress urinary incontinence (SUI) and pelvic organ prolapse (POP) in women is associated with significant complications in some women. This has recently become a public health issue with involvement of national parliaments and regulatory bodies. The occurrence of mesh complications is thought to be a result of multifactorial processes involving problems related to the material design, the surgical techniques used and disease, and patient-related factors. However, the infectious complications and mesh –tissue interactions are least studied. The aim o...
Source: World Journal of Urology - February 13, 2019 Category: Urology & Nephrology Source Type: research

Men ’s health on the web: an analysis of current resources
DiscussionThe lack of ‘relevant’ and HONcode-accredited websites relating to men’s health should be appreciated by health care professionals. (Source: World Journal of Urology)
Source: World Journal of Urology - February 12, 2019 Category: Urology & Nephrology Source Type: research

Live surgery in reconstructive urology: evaluation of the surgical outcome and educational benefit of the international meeting on reconstructive urology (IMORU)
ConclusionsThis is to our knowledge the first follow-up of LSE in the field of reconstructive urology. Rate of complications in general was acceptable. The performed survey showed participants value the quality and the educational benefit. Further studies are needed to improve learning possibilities. (Source: World Journal of Urology)
Source: World Journal of Urology - February 11, 2019 Category: Urology & Nephrology Source Type: research

Ureteral stenting practices following routine ureteroscopy: an international survey
AbstractPurposeStent omission after routine ureteroscopy (rtURS) is accepted by current guidelines and may result in decreased patient morbidity and treatment costs. In a value-based healthcare model, the added morbidity and cost of routine stent placement may be scrutinized. Furthermore, data are limited on urologist cost knowledge and it is effect on ureteral stent placement. As such, we seek to describe ureteral stenting practices and urologist cost knowledge amongst US and non-US-based urologists.MethodsThe ureteroscopic practice patterns and cost awareness of members of the Endourological Society were surveyed using a...
Source: World Journal of Urology - February 11, 2019 Category: Urology & Nephrology Source Type: research

Antibiotic prophylaxis in TURP: a prospective analysis concerning antibiotic stewardship and a potential reduction of antibiotic use in TURP
ConclusionsOur data show a low infectious complication rate (2.9%) in patients without a pre-operative catheter or pyuria,undergoing TURP without AB-prophylaxis. These findings might question the current use of AB prophylaxis in TURP in patients without a pre-operative catheter or pyuria, in times of antibiotic stewardship due to the high rate of microbial-resistance in our population. (Source: World Journal of Urology)
Source: World Journal of Urology - February 9, 2019 Category: Urology & Nephrology Source Type: research

The eye of the endourologist: what are the risks? A review of the literature
ConclusionsWhile the risks of infection, laser injury, lens opacity and cataract are generally low, the wear of protective glasses is recommended. Lead glasses may protect against all these risks in case of Ho:YAG laser use with concomitant X-ray radiation. If Ho:YAG laser is used without any concomitant X-ray radiation, proper laser safety glasses or at least conventional eyeglasses should be recommended. When other types of laser are used, we recommend wearing laser eye protection glasses covering the adequate range of wavelength. For endourological procedures without laser use and X-ray radiation, specific protection de...
Source: World Journal of Urology - February 8, 2019 Category: Urology & Nephrology Source Type: research

Re: Quantitation of hypoechoic lesions for the prediction and Gleason grading of prostate cancer: a prospective study
(Source: World Journal of Urology)
Source: World Journal of Urology - February 8, 2019 Category: Urology & Nephrology Source Type: research

Optimal sequencing strategy using docetaxel and androgen receptor axis-targeted agents in patients with castration-resistant prostate cancer: utilization of neutrophil-to-lymphocyte ratio
AbstractPurposeTo investigate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) for the selection of the optimal sequencing strategy using docetaxel and androgen receptor axis-targeted (ARAT) agents in patients with M0 or M1 castration-resistant prostate cancer (CRPC). Currently, there is a need to identify biomarkers to guide optimal sequential treatment in CRPC.MethodsThis multicenter, retrospective analysis included 303 consecutive patients initially diagnosed with M0 or M1 CRPC between September 2009 and March 2017. Of these, 52 (17.2%) patients received pre-docetaxel ARAT agents and 189 (62.4%) patients rec...
Source: World Journal of Urology - February 8, 2019 Category: Urology & Nephrology Source Type: research

‘En Bloc’ HoLEP with early apical release in men with benign prostatic hyperplasia
AbstractPurposeHoLEP represents an excellent treatment option for benign prostatic hyperplasia. Recently, ‘en bloc’ techniques resulting in improved visualization, shorter surgical times, and easier recognition of the dissection plane have been described. In this paper we describe the ‘En bloc’ HoLEP technique with early apical release.Materials and methodsBetween January 2015 and March 2017, 137 consecutive patients were subjected to this technique by a single surgeon. The following parameters were measured pre- and post-procedure: International Prostate Symptom Score (IPSS), maximum flow rate (Qma...
Source: World Journal of Urology - February 8, 2019 Category: Urology & Nephrology Source Type: research

Robotic versus laparoscopic radical nephrectomy: a large multi-institutional analysis (ROSULA Collaborative Group)
AbstractObjectiveTo compare the outcomes of robotic radical nephrectomy (RRN) to those of laparoscopic radical nephrectomy (LRN) for large renal masses.MethodsThis was a retrospective analysis of RRN and LRN cases performed for large ( ≥ cT2) renal masses from 2004 to 2017 and collected in the multi-institutional international database (ROSULA: RObotic SUrgery for LArge renal masses). Peri-operative, functional, and oncologic outcomes were compared between each approach. Descriptive analyses were performed and presented as me dians with interquartile ranges. Inverse probability of treatment weighting-ad...
Source: World Journal of Urology - February 7, 2019 Category: Urology & Nephrology Source Type: research

A systematic review of the clinical significance of nephrostomy urine cultures
ConclusionNephrostomy urine cultures have utility in clinical practice and can help support treatment and antimicrobial stewardship. (Source: World Journal of Urology)
Source: World Journal of Urology - February 7, 2019 Category: Urology & Nephrology Source Type: research

Impact of nadir PSA level and time to nadir during initial androgen deprivation therapy on prognosis in patients with metastatic castration-resistant prostate cancer
AbstractPurposeWe determine whether the nadir prostate-specific antigen level (PSA nadir) and time to nadir (TTN) during initial androgen deprivation therapy (ADT) are prognostic factors in metastatic castration-resistant prostate cancer (mCRPC) patients.MethodsWe reviewed the Michinoku Japan Urological Cancer Study Group database, including 321 mCRPC patients. Optimal cutoff values for PSA nadir and TTN on survival were calculated with the receiver operating characteristic (ROC) curve. Patients were stratified into unfavorable (higher PSA nadir and/or shorter TTN) and favorable (lower PSA nadir and longer TTN) groups. The...
Source: World Journal of Urology - February 7, 2019 Category: Urology & Nephrology Source Type: research

Thulium fiber laser: the new player for kidney stone treatment? A comparison with Holmium:YAG laser
ConclusionsThe Thulium fiber laser overcomes the main limitations reported with the Holmium:YAG laser relating to lithotripsy, based on preliminary in vitro studies. This innovative laser technology seems particularly advantageous for ureteroscopy and may become an important milestone for kidney stone treatment. (Source: World Journal of Urology)
Source: World Journal of Urology - February 6, 2019 Category: Urology & Nephrology Source Type: research

Evidence-based approach to active surveillance of prostate cancer
AbstractActive surveillance is a good management option for some men with non-metastatic prostate cancer. In this review, we examine the evidence for several topics related to active surveillance. We examine: (1) which patients should be eligible for active surveillance, (2) what follow-up (monitoring) protocols should be used for men on surveillance, (3) what is the role of prostate magnetic resonance imaging (MRI) for men on surveillance, and (4) what is the prognosis for men who choose surveillance compared to radical treatment. In many instances, the evidence is evolving or lacking. In these situations, we highlight th...
Source: World Journal of Urology - February 6, 2019 Category: Urology & Nephrology Source Type: research

Perioperative management of direct oral anticoagulants in patients undergoing radical prostatectomy: results of a prospective assessment
ConclusionOur report is the first to prospectively assess current guideline recommendations regarding DOAC restarting after major urological surgery. RP can safely be performed, if DOACs are correctly paused before surgery. Moreover, in case of an uneventful postoperative clinical course, DOACs can be safely restarted on the third postoperative day. A 9% Clavien  ≥ 3 30-day morbidity warrants attention and should be further explored in future studies. (Source: World Journal of Urology)
Source: World Journal of Urology - February 6, 2019 Category: Urology & Nephrology Source Type: research

Optimizing male fertility: oxidative stress and the use of antioxidants
ConclusionsProtective agents against ROS, such as antioxidants, may have positive effects on semen parameters in some patients, although a widespread indication is still restricted by practical aspects, including unknown physiological levels of ROS and controversy regarding different concentrations and combinations of drugs. (Source: World Journal of Urology)
Source: World Journal of Urology - February 4, 2019 Category: Urology & Nephrology Source Type: research

Stone composition independently predicts stone size in 18,029 spontaneously passed stones
AbstractPurposeTo evaluate whether the size of spontaneously passed stones (SPS) may be associated with clinical parameters.MethodsA search for SPS was conducted in our electronic stone database, comprising data on stones analyzed over the last 33  years at our institution. Adults with upper urinary tract stones were included. Cases with stenotic urinary tract disease or past history of anastomotic urinary tract surgery were excluded. Stone size expressed as maximal stone diameter (MSD) and stone volume (SV) was compared between groups by on e-way ANOVA. Logistic regression analyses were performed to identify predicto...
Source: World Journal of Urology - February 4, 2019 Category: Urology & Nephrology Source Type: research

Clinical significance of cystoscopic urethral stricture recurrence after anterior urethroplasty: a multi-institution analysis from Trauma and Urologic Reconstructive Network of Surgeons (TURNS)
ConclusionsMany patients with cystoscopic recurrence do not need an intervention after initial urethroplasty. Despite good negative predictive value, cystoscopy alone may be a poor screening test for stricture recurrence defined by patient symptoms and need for secondary interventions. (Source: World Journal of Urology)
Source: World Journal of Urology - February 2, 2019 Category: Urology & Nephrology Source Type: research

MRI-targeted biopsies: What ’s next?
(Source: World Journal of Urology)
Source: World Journal of Urology - February 2, 2019 Category: Urology & Nephrology Source Type: research

Suctioning ureteral access sheath use in flexible ureteroscopy might decrease operation time and prevent infectious complications
(Source: World Journal of Urology)
Source: World Journal of Urology - February 1, 2019 Category: Urology & Nephrology Source Type: research

Complications, oncological and functional outcomes of salvage treatment options following focal therapy for localized prostate cancer: a systematic review and a comprehensive narrative review
ConclusionsCurrent evidence is weak and limited to a few retrospective series. Oncological control is acceptable although it seems lower compared to a primary treatment setting. Functional outcomes are comparable to primary treatment with the exception of EF; overall, suggesting FT has little impact on subsequent salvage treatments. Future studies are needed to confirm the current findings. (Source: World Journal of Urology)
Source: World Journal of Urology - February 1, 2019 Category: Urology & Nephrology Source Type: research

Combined-modality 125 J-seed-brachytherapy, external beam radiation and androgen deprivation therapy of unfavorable-risk prostate cancer: report of outcomes and side-effects
AbstractPurposeTo analyze outcomes and complication rates in an unselected cohort of men with unfavorable (NCCN intermediate and high-risk) PCa receiving combined-modality radiation treatment (CRT).MethodsPatients received androgen deprivation therapy for 1  year and combined-modality radiation treatment (CRT) consisting of external-beam radiotherapy (EBRT, 59.4 Gy, 33 fractions) and125J seed-brachytherapy (S-BT, 100  Gy). Subgroups, including WHO group 3–5, and initial PSA (iPSA)   20 ng/ml were identified. Biochemical recurrence-free (BRFS), metastasis-free (MFS), cancer-specific (...
Source: World Journal of Urology - February 1, 2019 Category: Urology & Nephrology Source Type: research

Should partial nephrectomy be considered “elective” in patients with stage 2 chronic kidney disease? A comparative analysis of functional and survival outcomes after radical and partial nephrectomy
AbstractPurposeTo compare renal function and survival outcomes in patients with baseline chronic kidney disease (CKD) stage 2 undergoing partial (PN) or radical nephrectomy (RN), as nephron-sparing surgery is considered to be elective in this group.MethodsRetrospective analysis of patients with CKD stage 2 and T1/T2 renal mass  undergoing PN or RN from 2001 to 2015. Patients were stratified into substage CKD 2a or CKD 2b and analyzed between types of surgery. Primary outcome was overall survival (OS), eGFR 
Source: World Journal of Urology - February 1, 2019 Category: Urology & Nephrology Source Type: research

Letter to the Editor regarding the article “Meta-analysis of efficacy and safety of continuous saline bladder irrigation compared with intravesical chemotherapy after transurethral resection of bladder tumors”
(Source: World Journal of Urology)
Source: World Journal of Urology - February 1, 2019 Category: Urology & Nephrology Source Type: research

SIU Newsletter - March 2019
(Source: World Journal of Urology)
Source: World Journal of Urology - January 31, 2019 Category: Urology & Nephrology Source Type: research

A systematic review of contemporary management of oligometastatic prostate cancer: fighting a challenge or tilting at windmills?
AbstractPurposeAmongst the unanswered questions regarding prostate cancer (PCa), the optimal management of oligometastatic disease remains one of the major concerns of the scientific community. The very existence of this category is still subject to controversy. Aim of this systematic review is to summarize current available data on the most appropriate management of oligometastatic PCa.Evidence acquisitionAll relevant studies published in English up to November the 1st were identified through systematic searches in PubMed, EMBASE, Cochrane Library, CINAHL, Google Scholar and Ovid database. A search was performed including...
Source: World Journal of Urology - January 31, 2019 Category: Urology & Nephrology Source Type: research

Prevention of healthcare-associated infections (HAIs) in a surgical urology ward: observational study —analysis of the problem and strategies for implementation
ConclusionIt is essential to monitor the incidence of HAIs, and preventive measures play a useful role in reducing the rate of infection and in optimising their management. (Source: World Journal of Urology)
Source: World Journal of Urology - January 30, 2019 Category: Urology & Nephrology Source Type: research

Clinical relevance of gene expression in localized and metastatic prostate cancer exemplified by FABP5
AbstractPurposeFatty acid-binding protein 5 (FABP5), a transport protein for lipophilic molecules, has been proposed as protein marker in prostate cancer (PCa). The role ofFABP5 gene expression is merely unknown.MethodsIn two cohorts of PCa patients who underwent radical prostatectomy (n = 40 andn = 57) and one cohort of patients treated with palliative transurethral resection of the prostate (pTUR-P;n = 50)FABP5 mRNA expression was analyzed with qRT-PCR. Expression was correlated with clinical parameters. BPH tissue samples served as control. To independently validate findings onF...
Source: World Journal of Urology - January 30, 2019 Category: Urology & Nephrology Source Type: research

Health-related quality of life after radical cystectomy and ileal orthotopic neobladder: effect of detailed continence outcomes
AbstractPurposeTo objectively quantify continence rates and to correlate continence outcomes with health-related quality of life (HRQOL) after radical cystectomy and orthotopic ileal neobladder (ONB).MethodsQuestionnaires were sent to 244 patients who underwent radical cystectomy with ONB between 2004 and 2015, and information about the current continence status was retrieved. To objectify postoperative urine loss, daytime and nocturnal pad tests were performed. Continence was defined as need of up to one safety pad. HRQOL was assessed using EORTC QLQ-C30 scoring with global health status being the primary endpoint. Statis...
Source: World Journal of Urology - January 30, 2019 Category: Urology & Nephrology Source Type: research

Efficacy and safety of non-ablative vaginal erbium:YAG laser treatment as a novel surgical treatment for overactive bladder syndrome: comparison with anticholinergics and β3-adrenoceptor agonists
AbstractPurposeTo examine the efficacy and safety of non-ablative vaginal erbium:YAG laser (VEL) for the treatment of overactive bladder syndrome (OAB) compared with those of two other common pharmacotherapies, namely, anticholinergics and β3-adrenoceptor agonists.MethodsFemale subjects aged 60 –69 years who presented with symptoms of OAB from 2015 to 2017 were assigned to three groups (n = 50) receiving treatment with an anticholinergic agent (4 mg fesoterodine), a β3-adrenoceptor agonist (25 mg mirabegron), or VEL (20 min/session of VEL performed thrice). The OAB symptom ...
Source: World Journal of Urology - January 28, 2019 Category: Urology & Nephrology Source Type: research

Confocal laser endomicroscopy for upper tract urothelial carcinoma: validation of the proposed criteria and proposal of a scoring system for real-time tumor grading
ConclusionsBased on the previously proposed criteria, CLE enables accurate grading of papillary UTUC at a non-diagnostic rate of 19%. The most prevalent CLE criteria with the highest diagnostic potential for grading of papillary UTUC are cellular organization, morphology and cohesiveness of cells. The proposed scoring system may simplify the assessment of CLE images for UTUC grading but external validation is required. (Source: World Journal of Urology)
Source: World Journal of Urology - January 25, 2019 Category: Urology & Nephrology Source Type: research

SIU –ICUD consultation on bladder cancer: treatment of muscle-invasive bladder cancer
ConclusionA multi-disciplinary approach is paramount to achieving optimal outcomes for MIBC patients, irrespective of their age, performance and nutritional status, fitness/frailty, renal and other organ function, or disease severity. (Source: World Journal of Urology)
Source: World Journal of Urology - January 25, 2019 Category: Urology & Nephrology Source Type: research

Patients knowledge and experience with urinary and peripheral intravenous catheters
ConclusionsThere is a lack of knowledge about the indication for having a urinary and peripheral intravenous catheter in a substantial part of patients. Although catheters cause symptoms, patients in general do not ask if the catheter could be removed. Doctors should give more information and ask more questions about catheters to their patients. Quality improvement initiatives stimulating patients to actively participate in their treatment are needed. (Source: World Journal of Urology)
Source: World Journal of Urology - January 24, 2019 Category: Urology & Nephrology Source Type: research

Liquid chromatography –mass spectrometry identification of serum biomarkers for nocturia in aged men
This study enrolled 66 men aged 65 –80 years, recruited from the outpatient department of a university hospital. The participants were stratified as follows: Nocturia group [45 men with any total international prostate symptom score (IPSS) and an average of 3 nights ≥ 1.5 micturitions/night] and Control group (21 men with to tal IPSS 
Source: World Journal of Urology - January 23, 2019 Category: Urology & Nephrology Source Type: research

Musculocutaneous latissimus dorsi flap for phalloplasty in female to male gender affirmation surgery
ConclusionMusculocutaneous latissimus dorsi flap is a good choice for phalloplasty in gender affirmation surgery. It provides an adequate amount of tissue with sufficient blood supply for safe urethral reconstruction and penile prosthesis implantation. (Source: World Journal of Urology)
Source: World Journal of Urology - January 23, 2019 Category: Urology & Nephrology Source Type: research

Impact of intravesical therapy for non-muscle invasive bladder cancer on the accuracy of urine cytology
ConclusionsWhile urinary cytology maintains a high specificity following intravesical therapy, it demonstrates a low sensitivity for potentially aggressive high-grade urothelial carcinoma. Further evaluation of more effective, clinic-based enhanced cystoscopy techniques and biomarkers is warranted to better identify patients at risk for disease recurrence following BCG therapy. (Source: World Journal of Urology)
Source: World Journal of Urology - January 23, 2019 Category: Urology & Nephrology Source Type: research

A national survey of radiation oncologists and urologists on prediction tools and nomograms for localized prostate cancer
AbstractPurposeAlthough prediction tools for prostate cancer (PCa) are essential for high-quality treatment decision-making, little is known about the degree of confidence in existing tools and whether they are used in clinical practice from radiation oncologists (RO) and urologists (URO). Herein, we performed a national survey of specialists about perceived attitudes and use of prediction tools.MethodsIn 2017, we invited 940 URO and 911 RO in a national survey to query their confidence in and use of the D ’Amico criteria, Kattan Nomogram, and CAPRA score. The statistical analysis involved bivariate association and m...
Source: World Journal of Urology - January 22, 2019 Category: Urology & Nephrology Source Type: research

Focal laser ablation as clinical treatment of prostate cancer: report from a Delphi consensus project
ConclusionFocal laser ablation is a promising technique for treatment of clinically localized PCa and should ideally be performed within approved clinical trials. So far, only few studies have reported on FLA and further validation with longer follow-up is mandatory before widespread clinical implementation is justified. (Source: World Journal of Urology)
Source: World Journal of Urology - January 22, 2019 Category: Urology & Nephrology Source Type: research

SIU –ICUD consultation on bladder cancer 2018
(Source: World Journal of Urology)
Source: World Journal of Urology - January 21, 2019 Category: Urology & Nephrology Source Type: research

Salvage high-intensity focused ultrasound versus salvage radical prostatectomy for radiation-recurrent prostate cancer: a comparative study of oncological, functional, and toxicity outcomes
ConclusionS-HIFU and S-RP could both be considered valuable LST options for patients with radiation-recurrent nonmetastatic PCa with sufficient life expectancy. S-RP is associated with more pad-dependent patients at 12  months. (Source: World Journal of Urology)
Source: World Journal of Urology - January 21, 2019 Category: Urology & Nephrology Source Type: research

Simultaneous treatment of ureteropelvic junction obstruction complicated by renal calculi with robotic laparoscopic surgery and flexible cystoscope
ConclusionsRALP combined with flexible cystoscope lithotomy is safe and effective alternatives for the simultaneous management of UPJO complicated by renal caliceal stones. (Source: World Journal of Urology)
Source: World Journal of Urology - January 19, 2019 Category: Urology & Nephrology Source Type: research

Role of androgen receptor splice variants, their clinical relevance and treatment options
ConclusionThe methods used for detecting AR-Vs, at least on the mRNA level, are well-advanced and harbor the potential to be introduced into clinical diagnostics. It is important to note, that the testing, especially of AR-V7 has its limitations in predicting treatment response. More promising is the great number of active clinical trials aimed at reducing the AR-Vs, and using this to re-sensitize CRPC towards endocrine treatment might provide additional treatment options for CRPC patients in the future. (Source: World Journal of Urology)
Source: World Journal of Urology - January 19, 2019 Category: Urology & Nephrology Source Type: research

Clinically occult prostate cancer cases may distort the effect of testosterone replacement therapy on risk of PCa
ConclusionsTRT may make occult PCa cases detectable within early phase of treatment and present a beneficial effect in the long run. Future longitudinal studies are needed to confirm findings from our exploratory analyses. (Source: World Journal of Urology)
Source: World Journal of Urology - January 18, 2019 Category: Urology & Nephrology Source Type: research

The discrepancy between European Association of Urology (EAU) guidelines and daily practice in the evaluation and management of nocturia: results of a Dutch survey
ConclusionsThese observations mandate better education and campaigns to raise the awareness on the EAU-guideline recommendations for nocturia. (Source: World Journal of Urology)
Source: World Journal of Urology - January 17, 2019 Category: Urology & Nephrology Source Type: research

Prospective analysis of artificial urinary sphincter AMS 800 implantation after buccal mucosa graft urethroplasty
AbstractObjectivesTo analyze functional outcomes and complication rates of artificial urinary sphincter (AUS) implantation in patients who had undergone buccal mucosa graft urethroplasty (BMGU) beforehand.Patients and methodsThis prospectively maintained single-center database comprises data from 236 patients from 2009 to 2015 who underwent AUS implantation. A total of 17 patients after BMGU were available for analysis. Primary endpoints consisted of continence and complication rates. Continence was defined as no use of safety pads, social continence as
Source: World Journal of Urology - January 17, 2019 Category: Urology & Nephrology Source Type: research

In response to “Obstructive sleep apnea syndrome should always be screened in patients complaining of nocturia”. World J Urol. 2018
(Source: World Journal of Urology)
Source: World Journal of Urology - January 17, 2019 Category: Urology & Nephrology Source Type: research

Urologic provider experiences in transitioning spina bifida patients from pediatric to adult care
ConclusionsPotential solutions to improve the urologic care of this population suggest additional national provider resources, standardized guidelines, multidisciplinary collaboration, access to care, and an advanced-training pathway to improve care of adult patients with spina bifida. (Source: World Journal of Urology)
Source: World Journal of Urology - January 16, 2019 Category: Urology & Nephrology Source Type: research

A multicentric study on accurate grading of prostate cancer with systematic and MRI/US fusion targeted biopsies: comparison with final histopathology after radical prostatectomy
AbstractObjectiveTo evaluate the accuracy in histologic grading of MRI/US image fusion biopsy by comparing histopathology between systematic biopsies (SB), targeted biopsies (TB) and the combination of both (SB  + TB) with the final histopathologic outcomes of radical prostatectomy specimens.Materials and methodsRetrospective, multicentric study of 443 patients who underwent SB and TB using MRI/US fusion technique (Urostation® and Trinity®) prior to radical prostatectomy between 2010 and 2017. Cochran ’sQ test and McNemar test were conducted as a post hoc test. Uni-multivariable analyses were pe...
Source: World Journal of Urology - January 16, 2019 Category: Urology & Nephrology Source Type: research