The knowledge of cervical length is essential in decision-making for cervical cerclage
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 27, 2020 Category: OBGYN Authors: Amanda ROMAN, Vincenzo BERGHELLA Source Type: research

Incidence of Uterine Bleeding following Oral Anticoagulant Use in FDA ’s Sentinel System
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 26, 2020 Category: OBGYN Authors: Abby ANDERSON, Laura HOU, Efe EWORUKE, Hui-Lee WONG, David MOENY, Ting-Ying HUANG, Audrey GASSMAN Tags: Research Letter Source Type: research

Optimal use of intravenous tranexamic acid for hemorrhage prevention in pregnant women
Every 2 minutes there is a pregnancy related death worldwide, with one third due to severe postpartum hemorrhage (PPH). While international trials demonstrated efficacy of 1,000 mg TXA in treating PPH, to our knowledge there are no dose finding studies of TXA in pregnant women for PPH prevention. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 26, 2020 Category: OBGYN Authors: Homa K. AHMADZIA, Naomi L.C. LUBAN, Shuhui LI, Dong GUO, Adam MISZTA, Jogarao V.S. GOBBURU, Jeffrey S. BERGER, Andra H. JAMES, Alisa S. WOLBERG, John VAN DEN ANKER Tags: Original Research: Obstetrics Source Type: research

Assessing the Cognitive and Behavioral Development of 3-Year-Old Children Born from Fathers with Severe Male Infertility
Despite the large number of babies born worldwide following ICSI, concerns about the procedure ’s safety still exist due to the use of suboptimal spermatozoa. Thus, follow-up of ICSI children is highly recommended. We propose the use of parent-administered questionnaires to monitor ICSI offspring development. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 25, 2020 Category: OBGYN Authors: Stephanie Cheung, Queenie V. Neri, Jane Squires, Zev Rosenwaks, Gianpiero D. Palermo Tags: Original Research: Gynecology Source Type: research

Intrauterine fetoscopic laser surgery versus expectant management in stage 1 twin-to-twin transfusion syndrome: an international randomized trial.
ABSTRACT (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 25, 2020 Category: OBGYN Authors: Julien Stirnemann, Femke Slaghekke, Nahla Khalek, Norbert Winer, Anthony Johnson, Liesbeth Lewi, Mona Massoud, Laurence Bussieres, Philippe Aegerter, Kurt Hecher, Marie-Victoire Senat, Yves Ville Tags: Original Research: Obstetrics Source Type: research

Gardnerella vaginalis promotes group B Streptococcus vaginal colonization, enabling ascending uteroplacental infection in pregnant mice
Group B Streptococcus (GBS) is a common vaginal bacterium and leading cause of invasive fetoplacental infections. GBS in the vagina can invade through the cervix to cause ascending uteroplacental infections or can be transmitted to the neonate during vaginal delivery. Some studies have found that women with a “dysbiotic” polymicrobial and/or Lactobacillus-depleted vaginal microbiota are more likely to harbor GBS. Gardnerella vaginalis is often the most abundant bacteria in the vaginas of women with dysbiosis, while being detected at lower levels in most other women, and has been linked with several a dverse pre...
Source: American Journal of Obstetrics and Gynecology - November 25, 2020 Category: OBGYN Authors: Nicole M. Gilbert, Lynne R. Foster, Bin Cao, Yin Yin, Indira U. Mysorekar, Amanda L. Lewis Tags: Original Research: Obstetrics Source Type: research

Quantitative and Qualitative Assessment of an All-Inclusive Postpartum Human Papillomavirus Vaccination Program
A postpartum human papillomavirus (HPV) vaccination program was locally implemented to address low initiation rates among young adults. Within 20 months, the program achieved high vaccine initiation and series completion rates. Based on the program ’s success, it was expanded to all 36 counties served by a public hospital. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 25, 2020 Category: OBGYN Authors: Abbey B. BERENSON, Jacqueline M. HIRTH, Yong-Fang KUO, Richard E. RUPP Tags: Original Research: Gynecology Source Type: research

Maternal risk from thromboembolism needs to be reduced
The publication of the Society for Maternal-Fetal Medicine (SMFM) et  al1 represents an excellent opportunity to review the outcomes of competing clinical strategies for venous thromboembolism (VTE) prophylaxis and to consider the next steps for research that may inform clinical care. In the United States, recommendations from the American College of Obstetricians a nd Gynecologists (which SMFM Consult Series #51 largely aligns with) support perioperative mechanical prophylaxis for cesarean delivery and heparin prophylaxis for high-risk women with thrombophilia or previous VTE events. (Source: American Journal of Obst...
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: Alexander M. Friedman, Mary E. D ’Alton Tags: Editorial Source Type: research

Chorioamnionitis: Are we following diagnostic guidelines?
Chorioamnionitis is an intra-amniotic infection that causes inflammatory changes in the pregnant woman and can be associated with significant neonatal and maternal morbidity. The diagnosis is made through clinical evaluation of multiple signs and symptoms, varying greatly by provider and institution. Recently, a push has been made to narrow diagnostic criteria to reduce unwarranted interventions including overuse of antibiotics, prolonged hospitalization, and separation of mother and infant. A 2015 collaborative workshop with the Eunice Kennedy Shriver Institute, SMFM, ACOG, and AAP outlined recommended diagnostic criteria...
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: B.K. Neuhoff, J. Wells, S. Whitfield, A. Tufton, S. Olister, S. Holman Tags: IDSOG Oral Presentation Source Type: research

Association of chorioamnionitis and patent ductus arteriosus in a national U.S. cohort
Prior data from small clinical cohorts have suggested a possible association between chorioamnionitis and patent ductus arteriosus (PDA) at birth. Our objective was to determine whether chorioamnionitis is associated with PDA in a large national sample. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: C.A. Green, D. Westreich, M. Laughon, D.M. Stamilio, J.J. Reese, E.L. Shelton, K.K. Venkatesh Tags: IDSOG Oral Presentation Source Type: research

Implementing a penicillin allergy de-labelling service for the obstetric population
Given the negative consequences associated with an unverified allergy status and the importance of penicillin during delivery, evaluation of penicillin allergy in the pregnant population is essential. Our study proposes a clinic model to evaluate and de-label penicillin allergy in antenatal women. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: B.Y. Zhang, R. Mak, V. Paquette, M. Watt, A. Albert, C. Elwood Tags: IDSOG Oral Presentation Source Type: research

Postpartum inpatient admissions for pyelonephritis in the United States associated with high rates of severe maternal morbidity
The risks associated with pyelonephritis to pregnant patients are well-appreciated. However, it is not clear whether these risks abate in the postpartum period. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: K. Addae-Konadu, J. Federspiel, L. Wein, R.P. Heine, B. Hughes, S.K. Dotters-Katz Tags: IDSOG Oral Presentation Source Type: research

Influenza and pertussis transplacental antibody transfer in women with and without preeclampsia
To evaluate antibody transplacental transfer ratios of influenza and pertussis-specific IgG1 in women with and without preeclampsia. Secondarily, to evaluate whether time from vaccination to delivery impacted IgG1 transfer ratios. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: N. Teodoro, A.Y. Collier, M. Jennewein, D. Barouch, G. Alter Tags: IDSOG Oral Presentation Source Type: research

Associations between HIV, antiretroviral therapy, and preterm birth in the women ’s interagency HIV study, 1994-2018
The extent to which HIV and antiretroviral therapy (ART) increase the risk of preterm birth (PTB) remains to be fully defined. We evaluated the effects of HIV on PTB, and ART on PTB in the Multicenter AIDS Cohort Study (MACS) / Women ’s Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: K.K. Venkatesh, A. Edmonds, D. Westreich, J. Dionne-Odom, D.J. Weiss, A. Sheth, H. Cejtin, D. Seidman, S. Kassaye, H. Minkoff, J.M. Atrio, L. Rahangdale, A.A. Adimora Tags: IDSOG Oral Presentation Source Type: research

HIV testing after the first antenatal care visit during pregnancy and breastfeeding: Results from the first five quarters in 22 pepfar countries, September 1, 2018 – December 31, 2019
Acquisition of HIV during pregnancy and breastfeeding (BF) is associated with an increased risk of perinatal transmission and accounts for about a third of infant HIV infections in high prevalence areas. Retesting during pregnancy and BF allows for early diagnosis of incident infections, and testing of women missed at first antenatal care visit (ANC1) allows provision of optimal maternal treatment and infant prophylaxis and, if needed, treatment. In October 2018, PEPFAR added a new post-ANC1 disaggregation to its data collection system to monitor and promote increased HIV retesting in PEPFAR-supported programs with high HI...
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: D.H. Watts, J. Albertini, A. Vrazo Tags: IDSOG Oral Presentation Source Type: research

Variation of CD4 count in pregnant women living with HIV
The CD4+ T lymphocyte count gives crucial information on the status of a patient ’s immune system and can be affected by several factors, including pregnancy. In HIV seropositive pregnant women, a steady decline of CD4 percentages has been observed during pregnancy and post-partum. Drastic variations in recommendations for CD4 monitoring among pregnant women living with HIV (W LWHIV) between countries create a necessity for further research on the matter. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: M. Byrns, C. Elwood, P. Capmas, F. Kakkar, M. Boucher, D. Money, I. Boucoiran Tags: IDSOG Oral Presentation Source Type: research

Trichomonas vaginalis infection and preterm birth among a high-risk obstetric cohort in Atlanta, Georgia
Trichomoniasis is highly prevalent but its causal relationship with adverse perinatal outcomes remains disputed. Several studies demonstrate increased risk of preterm birth (PTB) with trichomoniasis, but a randomized control trial found increased risk of PTB after treating asymptomatic women. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: M. Young, K. Wall, E.R. Goggins, D.J. Jamieson, L.B. Haddad Tags: IDSOG Oral Presentation Source Type: research

An evaluation of the performance characteristics of the World Health Organization ’s syndromic diagnosis for c. trachomatis and n. gonorrhoeae infections among high risk women in Mombasa, Kenya
To assess the performance characteristics of the World Health Organization ’s (WHO) syndromic surveillance algorithms for the management of C. trachomatis (CT) and N. gonorrhoeae (GC) compared to nucleic acid amplification testing (NAAT) in a cohort of cisgender women at high risk of sexually transmitted infections (STIs) in Mombasa, Kenya. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: G. Zane, L. Masese, E. Kabare, L. Adala, J. Shafi, G. Manguro, R. Deya, V. Mochache, W. Jaoko, K. Mandaliya, C. Khosropour, R.S. McClelland, J. Balkus Tags: IDSOG Oral Presentation Source Type: research

Effect of bacterial vaginosis on fecundability among HIV-negative Kenyan women planning pregnancies
Bacterial vaginosis (BV) is common among women with infertility and has been associated with poor in vitro fertilization outcomes; its association with non-medically assisted conception has not been thoroughly explored. We assessed the association between BV and fecundability (per-cycle probability of pregnancy). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: E.M. Lokken, L.E. Manhart, J. Kinuthia, J.P. Hughes, C.S. Jisuvei, K. Mwinyikai, C.H. Muller, K. Mandaliya, W. Jaoko, R.S. McClelland Tags: IDSOG Oral Presentation Source Type: research

In vitro activity of ibrexafungerp in pH 7.0 and pH 4.5 testing environments against 187 fluconazole-susceptible and -resistant candida species from vulvovaginal candidiasis patients
Recent studies report a rapidly growing incidence Candida spp. resistance, notably C. glabrata, C. parapsilosis, and C. krusei; and an increase in fluconazole (FLU) resistance observed in C. albicans vaginal isolates in patients with Vulvovaginal Candidiasis (VVC). Previous in vitro studies have shown that fluconazole in low pH testing environments, pH 4.5, has a negative effect on the activity of fluconazole. Ibrexafungerp is an oral anti-fungal agent, that belongs to a novel class of glucan synthase inhibitors, triterpenoids, and has shown activity against azole-resistant Candida species. (Source: American Journal of Obs...
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: J. Sobel, K. Borroto-Esoda, N. Azie, D. Angulo Tags: IDSOG Oral Presentation Source Type: research

Oral ibrexafungerp efficacy and safety in the treatment of vulvovaginal candidiasis: A phase 3, randomized, blinded, study vs. placebo (VANISH-303)
We present the first of two phase 3 studies evaluating the safety and efficacy of oral ibrexafungerp in VVC. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: J.R. Schwebke, V. Sorkin-Wells, N. Azie, D. Angulo, J. Sobel Tags: IDSOG Oral Presentation Source Type: research

Pattern of anti-fungal resistance among vulvovaginal candida species
This study aims to examine the resistance of candida to anti-fungal medications, including new generations of anti-fungals. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: A.M. Boyd-Tressler, MengYao, G. Procop, T. Goje Tags: IDSOG Oral Presentation Source Type: research

A phase 3, multi-center, prospective, randomized, placebo-controlled, delayed treatment, double-blind study to evaluate the effectiveness and safety of a single oral dose of 2 grams of secnidazole for the treatment of trichomoniasis in women
The objective of this study was to evaluate the efficacy and safety of single-dose secnidazole 2g oral granules in women with trichomoniasis. (Secnidazole is approved by the FDA to treat bacterial vaginosis). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: C.A. Muzny, J.R. Schwebke, P. Nyirjesy, G. Kaufman, L.A. Mena, G.B. Lazenby, O.T. Van Gerwen, K.J. Graves, J. Arbuckle, B.A. Carter, C.P. McMahon, J. Shaw, B. Pandey, S.E. Chavoustie Tags: IDSOG Oral Presentation Source Type: research

Loss of function of nitric oxide reductase associated with neisseria gonorrhoeae infection in women
Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection gonorrhea, must adapt to the variable selective pressures in the anatomical sites it infects. Previous work has shown that sexual behavior —heterosexual and men-who-have-sex-with-men networks—has influenced N. gonorrhoeae population structure and that genetic variants influencing antibiotic susceptibility are adaptive for infection in particular body sites. We aimed to identify genetic variation associated with sexual behavior and site of infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: T.D. Mortimer, K.C. Ma, Y.H. Grad Tags: IDSOG Oral Presentation Source Type: research

Macrophage production of matrix metalloproteases in the setting of chorioamnionitis
The objective of this project is to determine whether maternal cytotrophoblasts (CTBs) decrease macrophage expression of tissue-remodeling MMPs in the setting of GBS infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: E. Vrana, D. Aronoff, A. Eastman Tags: IDSOG Oral Presentation Source Type: research

Lactobacillus iners growth inhibition by cystine uptake inhibitors is a target for shifting cervicovaginal microbiota towards lactobacillus crispatus-dominant communities
Cervicovaginal microbiota domination by Lactobacillus crispatus is associated with beneficial health outcomes, whereas Lactobacillus iners dominance has more adverse associations. However bacterial vaginosis (BV) treatment typically leads to domination by L. iners rather than L. crispatus. L. iners differs from other lactobacilli by its inability to grow in Lactobacillus MRS media. We hypothesized that investigating this growth difference would identify targets for selective L. iners inhibition. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: S.M. Bloom, N.A. Mafunda, B.M. Woolston, M.R. Hayward, J.F. Frempong, J. Xu, A. Mitchell, X. Westergaard, J.K. Rice, N. Choksi, E.P. Balskus, C.M. Mitchell, D.S. Kwon Tags: IDSOG Oral Presentation Source Type: research

Characterization of meconium-associated microbiota by cpn60-based microbiome profiling underscores the need for robust negative controls in the study of low microbial biomass samples
Many studies of placental, meconium or amniotic fluid microbiomes fail to account for the low-level contamination present in all sequencing experiments and do not implement adequate negative controls when interpreting results. We aimed to define and quantify the microbial content of meconium under properly controlled conditions. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: S.J. Dos Santos, Z. Pakzad, C. Elwood, A. Albert, J.E. Hill, D. Money, The Maternal Microbiome Legacy Project Team Tags: IDSOG Oral Presentation Source Type: research

Metagenomic next generation sequencing analysis of vaginal microbiome composition in patients with bacterial vaginosis treated with lactin-v (Lactobacillus crispatus CTV-05) versus placebo
BV affects 15% –50% of women, frequently recurs after antibiotic treatment and is associated with an increased risk of acquiring sexually transmitted infections including HIV, and preterm birth. We recently completed a Phase 2B placebo-controlled trial of LACTIN-V (formulated vaginal Lactobacillus crispatus CTV- 05) dosed over 11 weeks that demonstrated efficacy in the prevention of recurrent BV following use of vaginal metronidazole. In the intervention arm, 79% of participants were colonized with L. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: S.L. Hao, G.R. Castaneda, C.R. Cohen, A. Hemmerling, E.D. Crawford Tags: IDSOG Oral Presentation Source Type: research

Late-season influenza: Don't let your guard down!
Influenza season traditionally lasts 3-4 months, starting in December, lasting through March. Increasing data suggest that as the time since vaccination increases, vaccine efficacy decreases. With many pregnant women getting influenza vaccines in September and October, they may have increased risk for late-season influenza. Additionally, outside traditional influenza season, providers may be less apt to suspect influenza, leading to delay in diagnosis. Data regarding the incidence and morbidity associated with late-season influenza in pregnancy is not well described. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: A.J. Darling, J. Federspiel, L. Wein, G.K. Swamy, S.K. Dotters-Katz Tags: IDSOG Oral Presentation Source Type: research

Assessing influenza vaccination behaviors among medically underserved obstetric patients
To examine rates of influenza vaccine uptake among medically underserved obstetric patients. To compare reasons for vaccine refusal among women who consistently refused vaccination and women who accepted after refusing initially. To explore variations in vaccine uptake by concordance of patient and provider race/ethnicity. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: E.R. Goggins, R. Williams, T.G. Kim, J.C. Adams, M.J. Davis, M. McIntosh, M. Uzor, F. Geary, D.J. Jamieson, S. Boulet Tags: IDSOG Oral Presentation Source Type: research

Canadian surveillance of COVID-19 in pregnancy: Epidemiology and maternal and infant outcomes
To describe the Canadian approach to rapid epidemic surveillance through the CANCOVID-Preg network. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: E. McClymont, D.B. Fell, A. Albert, G.D. Alton, J. Barrett, D. El-Chaar, J. Harrold, M. Krajden, N. Lipsky, E. Maan, A.K. Malinowski, M. Othman, A. Raeside, J. Ray, A. Roberts, G. Ryan, M. Sadarangani, L. Sauve, J. van Schalkwyk, P. Shah, J.W. Snelgrove, Tags: IDSOG Oral Presentation Source Type: research

Health disparities among pregnant women with sars-cov-2 infection at a university medical center in northern California
We describe the prevalence of SARS-CoV2 and characteristics in pregnant women at a university medical center in Northern California to identify potential risk factors for infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: I. Igbinosa, K.B. Lee, A.M. Oakeson, E. Riley, S. Melchor, J. Birdsong, L. Tran, Y. Weng, W.J. Collins, G. Abir, Y.K. Bianco, Z. He, M. Desai, R. Mathew, G. Lee, N. Ahuja, D. Lyell, R. Gibbs, N. Aziz Tags: IDSOG Oral Presentation Source Type: research

Perspectives of women receiving treatment for hepatitis c virus during pregnancy
Describe the perspectives of pregnant women with chronic HCV infection receiving ledipasvir/sofosbuvir (LDV/SOF) therapy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: Y. Kislovskiy, J. Chang, E. Flaherty, M.E. Hamm, F. de Abril Cameron, E.E. Krans, C.A. Chappell Tags: IDSOG Oral Presentation Source Type: research

Withdrawn
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Tags: IDSOG Oral Presentation Source Type: research

Chagas disease screening using point of care testing in an at-risk obstetric population
Chagas Disease (CD) has emerged as a public health concern in non-endemic countries including the US where congenital transmission is the most common mode of transmission. Approximately 40,000 women of childbearing age are infected in the US. Women with CD transmit the disease to their babies during pregnancy at a rate of 1-10%, resulting in congenital Chagas. Most individuals infected are asymptomatic making CD challenging to diagnose and treat. If untreated, 20-30% will progress to the “determinate” disease form, characterized by irreversible and debilitating heart and gastrointestinal disease. (Source: Ameri...
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: L.E. Zamora, F. Palacio, D.S. Kozlowski, K. Doraivelu, C.M. Dude, D.J. Jamieson, L.B. Haddad Tags: IDSOG Oral Presentation Source Type: research

Use of fertility awareness methods as a safer conception strategy for women in HIV serodiscordant relationships
To assess the use of fertility awareness methods [FAM] and evaluate the drivers of alignment between indicators of fertility and sexual behavior among HIV serodiscordant couples attempting pregnancy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: Y. Zia, J. Velloza, L. Oluoch, R. Momanyi, S. Mbugua, J. Njoroge, S. Gakuo, E. Mugo, N. Thuo, C. Kiptinness, N. Njuguna, K. Ngure, N. Mugo, R. Heffron Tags: IDSOG Oral Presentation Source Type: research

Positive participant experiences with smart-phone based enhanced visualization with acetic acid for cervical cancer screening in mysore, India
The goal of this study was to evaluate the experiences of participants screened with a smart-phone based imaging system for enhanced visualization with acetic acid (VIA) for cervical cancer screening where Pap smears are not feasible in semi-urban and rural Mysore, India. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: S. Herbst de Cortina, V. Srinivas, P. Jayakrishna, A. Khan, K. Ravi, P. Adsul, P. Madhivanan Tags: IDSOG Oral Presentation Source Type: research

Expedited partner therapy in school-based health centers: The right choice for the right patient
The objective of this study was to assess the implementation and acceptability of EPT delivery in SBHCs. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: L. Adkins, J. Bell, A. Tilea, N. Speck, A. Kuznia, O. Mmeje Tags: IDSOG Poster Presentation Source Type: research

Using thinprep ® pap smear samples to evaluate sexually transmitted infection screening practices
Pap smear samples run through transcription-mediated amplification technology could enable efficient, accurate, and robust screening for sexually transmitted infections (STIs) in women. The study objective was to evaluate the use of ThinPrep ® samples obtained during Pap tests as a screening tool for STIs. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: S. Bell, M.E. Rowe, E.K. Kobernik, K. McKee, W. LeBar, J. Bell Tags: IDSOG Poster Presentation Source Type: research

A qualitative comparison of society guidelines for syphilis screening in pregnancy
A qualitative comparison of society guidelines from stakeholders who care for pregnant women and/or children potentially affected by syphilis or congenital syphilis was conducted to evaluate for potential modifications and recommendations. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: P.K. Bradley, I. Sandquist, M. Silio Tags: IDSOG Poster Presentation Source Type: research

Testing for three common sexually transmitted infections with a single FDA-cleared amplified molecular assay
Trichomonas vaginalis (TV), Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) are the most common non-viral sexually transmitted infections in the United States in young women, with higher TV prevalence often noted in older women. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: B. Van Der Pol, M. Broache, E. Torres-Chavolla, S. Taylor, M. Augenbraun, K. Fife, T. Davis, C.A. Gaydos Tags: IDSOG Poster Presentation Source Type: research

Inflammatory pathways within specific mucosal cell populations shed light on microbiome-associated inflammation in the female genital tract mucosa
The microbiome of the female genital tract (FGT) has been implicated in a variety of reproductive health outcomes, including HIV acquisition. A microbiome dominated by Lactobacillus crispatus is associated with low levels of mucosal inflammation, while diverse microbial communities rich in anaerobes are associated with inflammation and increased HIV acquisition risk. It is unclear how these microbial communities interact with the local mucosal immune environment in a way that might generate an inflammatory response and thereby heighten HIV acquisition risk. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: E.H. Byrne, M. Farcasanu, S.M. Bloom, N. Xulu, J. Xu, S.A. Handley, J. Bramante, C.M. Mitchell, A.-C. Villani, D.S. Kwon Tags: IDSOG Poster Presentation Source Type: research

Adjustable algorithmic tool for assessing the effectiveness of maternal respiratory syncytial virus (RSV) vaccination on infant mortality in developing countries
Acute lower respiratory infection (ALRI) due to RSV, is a common cause of global infant mortality, with most cases occurring in developing countries. Using data specific to priority countries as designated by the United States Agency for Independent Development (USAID), we created an adjustable algorithmic tool for visualizing the effectiveness of maternal RSV vaccination on infant mortality. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: R. Cevigney, C. Leary, B. Gonik Tags: IDSOG Poster Presentation Source Type: research

Listeria in pregnancy: What are the maternal outcomes?
The fetal and neonatal outcomes associated with Listeria infection in pregnancy are well known. Maternal outcomes are incompletely described. We sought to describe the maternal morbidity associated with Listeria infection in pregnancy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: A.M. Craig, J. Federspiel, L. Wein, J.L. Thompson, S.K. Dotters-Katz Tags: IDSOG Poster Presentation Source Type: research

The impact of anemia on infectious and obstetric outcomes of women with pyelonephritis
To determine if pregnant patients with both pyelonephritis and anemia have an increased risk of adverse pregnancy outcomes compared with pyelonephritis patients without anemia. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: H.M. Cunningham, J.J. Federspiel, L. Wein, A.E. DeNoble, R.P. Heine, S.K. Dotters-Katz Tags: IDSOG Poster Presentation Source Type: research

Secondary infertility and bacterial sexually transmitted infections in Cameroon, Africa
The goal of this study was to examine independent correlates of secondary infertility among women in Cameroon where STI screening is infrequent. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: C.E. Mbah, A. Jasani, K.J. Aaron, W. Geisler, B. Van Der Pol, A. Tita, J.N. Assob, J. Dionne-Odom Tags: IDSOG Poster Presentation Source Type: research

Comparison of lactate and procalcitonin levels in pregnant women with vs without intraamniotic infection during the peripartum period: The serum biomarkers of infection in labor evaluation (SMILE)
Serum biomarkers are used to diagnose and manage severe infections, but data on their utility during labor are limited. We compared lactate and procalcitonin levels in women with vs without intraamniotic infection (IAI) to determine if they are useful biomarkers. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: S.C. Do, H. Miller, S.A. Leonard, I. Datoc, A. Girsen, S. Kappagoda, R. Gibbs, N. Aziz Tags: IDSOG Poster Presentation Source Type: research

Evaluating the effect of mandatory prenatal syphilis screening laws on primary and secondary syphilis among women over time
To evaluate the association between state-specific prenatal syphilis screening laws and rates of primary and secondary syphilis among women over time. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: Y. Fomina, A. Chacko, D.D. McIntire, E.H. Adhikari Tags: IDSOG Poster Presentation Source Type: research

Identification of differentially expressed genes in metronidazole-resistant trichomonas vaginalis isolates
Trichomonas vaginalis is the most common non-viral sexually transmitted infection. 5-nitroimidazoles (i.e., metronidazole [MTZ] and tinidazole) are the only FDA-approved medications. Resistance to MTZ has ranged from 2-10%, but the true prevalence is unknown due to lack of surveillance data. We aimed to analyze gene-expression patterns of MTZ-resistant and MTZ-sensitive T. vaginalis isolates to gain insight into resistance mechanisms. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: K.J. Graves, A.P. Ghosh, J.R. Schwebke, J. Novak, C.A. Muzny Tags: IDSOG Poster Presentation Source Type: research

"Coronavirus has changed everything ”: experiences of pregnancy and birth among women impacted by the COVID-19 pandemic
The Coronavirus (COVID-19) pandemic has introduced an unprecedented context of global uncertainty, which may have a unique impact on pregnant and postpartum women. This work seeks to characterize the pregnancy, birth, and postpartum experiences of women impacted by the COVID-19 pandemic. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - November 24, 2020 Category: OBGYN Authors: E. Jaffe, K. Sullivan, N. Spach, A. Munson, I. Goldfarb Tags: IDSOG Poster Presentation Source Type: research