Definition Development and Prevalence of New Persistent Opioid Use Following Hysterectomy
Opioids used for postoperative pain control after surgery have been associated with an increased risk of chronic opioid use. Hysterectomy is the most common major gynecologic procedure in the United States; however, we lack a data-driven definition of new persistent opioid use specific to hysterectomy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 18, 2018 Category: OBGYN Authors: Carolyn W. Swenson, Neil S. Kamdar, Kristian Seiler, Daniel M. Morgan, Paul Lin, Sawsan As-Sanie Source Type: research

Diagnostic accuracy of 4th generation ARCHITECT HIV Ag/Ab Combo assay and utility of signal-to-cutoff ratio to predict false positive HIV tests in pregnancy
False positive HIV screening tests in pregnancy may lead to unnecessary interventions in labor. In 2014, the Centers for Disease Control and Prevention released a new algorithm for HIV diagnosis using a 4th generation screening test, which detects antibodies to HIV as well as p24 antigen and has a shorter window period compared with prior generations. A reactive screen requires a differentiation assay, and supplemental qualitative RNA testing is necessary for nonreactive differentiation assay. One screening test, the ARCHITECT Ag/Ab Combo assay, is described to have 100% sensitivity and>99% specificity in non-pregnant p...
Source: American Journal of Obstetrics and Gynecology - June 15, 2018 Category: OBGYN Authors: Emily H. Adhikari, Devin Macias, Donna Gaffney, Sarah White, Vanessa L. Rogers, Donald D. McIntire, Scott W. Roberts Source Type: research

Implementation of an Urogynecology-Specific Enhanced Recovery After Surgery (ERAS) Pathway
ERAS protocols were developed for colorectal surgery to hasten post-op recovery. Variations of the protocol are being adopted for gynecologic procedures despite limited population and procedure-specific outcome data. Our objective was to evaluate if implementation of an ERAS pathway would facilitate reduced length of admission in an urogynecology population. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 15, 2018 Category: OBGYN Authors: Charelle M. Carter-Brooks, Angela L. Du, Kristine M. Ruppert, Anna L. Romanova, Halina M. Zyczynski Source Type: research

Low dose aspirin is associated with reduced spontaneous preterm birth in nulliparous women
Preterm birth (PTB) is one of the leading causes of perinatal morbidity and mortality. Clinical data suggests that low dose aspirin may decrease the rate of overall PTB, but investigators have speculated that this is likely due to a decrease in medically indicated PTB through its effect on the incidence of preeclampsia and other placental disease. We hypothesized that low dose aspirin may also impact the mechanism of spontaneous preterm labor. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 15, 2018 Category: OBGYN Authors: Maria Andrikopoulou, Stephanie E. Purisch, Roxane Handal-Orefice, Cynthia Gyamfi-Bannerman Source Type: research

Longitudinal changes in pelvic floor muscle strength among parous women
There is limited knowledge of the effects of time on change in pelvic floor muscle strength after childbirth. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 11, 2018 Category: OBGYN Authors: Emily N.B. Myer, Jennifer L. Roem, David A. Lovejoy, Melinda G. Abernethy, Joan L. Blomquist, Victoria L. Handa Source Type: research

Randomized Controlled Trial of Belladonna and Opiate Suppository during Intravesical Onabotulinum Toxin A Injection
Intravesical injection with onabotulinum toxin A (BTX-A) injection can be performed in-office under local anesthesia. Rectally administered pain medication presents a potentially feasible and previously uninvestigated adjunct to office-based anesthesia protocols. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 11, 2018 Category: OBGYN Authors: Edgar L. Leclaire, Jennifer Duong, Rachel M. Wykes, Kevin E. Miller, Tessa L. Winterton, Milan Bimali Source Type: research

Timing of Gestational Exposure to Zika Virus is Associated with Postnatal Growth Restriction in a Murine Model
Vertical transmission of Zika virus (ZIKV) leads to infection of neuroprogenitor cells and destruction of brain parenchyma. Recent evidence suggests that the timing of infection as well as host factors may affect vertical transmission. As a result, congenital ZIKV infection may only become clinically apparent in the postnatal period. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 11, 2018 Category: OBGYN Authors: Gregory C. Valentine, Maxim D. Seferovic, Stephanie W. Fowler, Angela M. Major, Rodion Gorchakov, Rebecca Berry, Alton G. Swennes, Kristy O. Murray, Melissa A. Suter, Kjersti M. Aagaard Source Type: research

A Conceptual Framework for the Impact of Obesity on Risk of Cesarean Delivery
Cesarean deliveries accounted for 32.2% of nearly 4 million births in the United States in 2014. Obesity affects a third of reproductive age women and is associated with worse cesarean delivery outcomes. Studies have shown that increasing maternal body mass index correlates linearly with cesarean delivery rates, but little is known about the potential mediating and moderating mechanisms. Thus, a conceptual framework for understanding how obesity correlates with risk of cesarean delivery is crucial to determining safe ways to reduce the cesarean delivery rate among obese gravidas. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 11, 2018 Category: OBGYN Authors: Anna Joy G. Rogers, Lorie M. Harper, Giancarlo Mari Tags: Clinical Opinion Source Type: research

Postponing Early intrauterine Transfusion with Intravenous immunoglobulin Treatment; the PETIT study on severe hemolytic disease of the fetus and newborn
Intrauterine transfusion for severe alloimmunization in pregnancy performed before 20 weeks ’ gestation is associated with a higher fetal death rate. Intravenous immunoglobulins may prevent hemolysis and could therefore be a non-invasive alternative for early transfusions.Objective(s): We evaluated whether maternal treatment with intravenous immunoglobulins defers the development of seve re fetal anemia and its consequences in a retrospective cohort to which 12 fetal therapy centers contributed. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 11, 2018 Category: OBGYN Authors: Carolien Zwiers, Johanna G. van der Bom, Inge L. van Kamp, Nan Van Geloven, Enrico Lopriore, John Smoleniec, Roland Devlieger, Pauline E. Sim, Marie Anne Ledingham, Eleonor Tiblad, Kenneth J. Moise, Karl-Philip Gloning, Mark D. Kilby, Timothy G. Overton, Source Type: research

Use of non-steroidal anti-inflammatory drugs during pregnancy and the risk of miscarriage
Non-steroidal anti-inflammatory drugs (NSAIDs) remain one of the medications most widely used by pregnant women, and previous studies reported an increased risk of miscarriage associated with NSAID use during pregnancy. Although the findings have not always been consistent, there is a well-established mechanism for the association: NSAIDs inhibit the production of prostaglandin, which is essential for successful embryonic implantation. Abnormal implantation increases the risk of miscarriage. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 8, 2018 Category: OBGYN Authors: De-Kun LI, Jeannette R. Ferber, Roxana Odouli, Charles Quesenberry Tags: Original Research: Gynecology Source Type: research

Uterine arteriolar injuries in chronic hypertension
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 6, 2018 Category: OBGYN Authors: Mj Quinn Tags: Letter to the Editors Source Type: research

Reply
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 6, 2018 Category: OBGYN Authors: Samuel Parry Tags: Letter to the Editors Source Type: research

Is fetal heart rate “deceleration-area” the silver bullet for detection of acidemia?
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 6, 2018 Category: OBGYN Authors: Shashikant L. Sholapurkar Tags: Letter to the Editors Source Type: research

Uterine artery Doppler studies in the early second trimester to predict abnormal pregnancy outcome in nulliparous women
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 6, 2018 Category: OBGYN Authors: Roger A. Mcmaster-Fay, Jonathan A. Hyett Tags: Letter to the Editors Source Type: research

Application of a preeclampsia screening algorithm in a low-risk nulliparous population
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 6, 2018 Category: OBGYN Authors: Fionnuala Mone, Fergal D. Malone, Fionnuala M. Mcauliffe Tags: Letter to the Editors Source Type: research

Letter to the editor
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 6, 2018 Category: OBGYN Authors: T.K.J. Groenhof, W. Ganzevoort, A.T. Lely Tags: Letter to the Editors Source Type: research

Utilization of Ovarian Transposition for Fertility Preservation among Young Women with Pelvic Malignancies Who Undergo Radiotherapy
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 5, 2018 Category: OBGYN Authors: Jessica Selter, Yongmei Huang, Lisa C. Grossman Becht, Cande V. Ananth, Alfred I. Neugut, Dawn L. Hershman, Jason D. Wright Tags: Research Letter Source Type: research

Prenatal therapy with pyrimethamine  + sulfadiazine vs spiramycin to reduce placental transmission of toxoplasmosis: a multicenter, randomized trial
The efficacy of prophylaxis to prevent prenatal toxoplasmosis transmission is controversial, without any previous randomized clinical trial. In France, spiramycin is usually prescribed for maternal seroconversions. A more potent pyrimethamine  + sulfadiazine regimen is used to treat congenital toxoplasmosis and is offered in some countries as prophylaxis. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 2, 2018 Category: OBGYN Authors: Laurent Mandelbrot, Fran çois Kieffer, Rémi Sitta, Hélène Laurichesse-Delmas, Norbert Winer, Louis Mesnard, Alain Berrebi, Gwenaëlle Le Bouar, Jean-Paul Bory, Anne-Gaëlle Cordier, Yves Ville, Franck Perrotin, Jean-Marie Jouannic, Florence Biquard, C Tags: Original Research Source Type: research

Prenatal therapy with pyrimethamine + sulfadiazine versus spiramycin to reduce placental transmission of toxoplasmosis : A multicenter, randomized trial
The efficacy of prophylaxis to prevent prenatal toxoplasmosis transmission is controversial, without any previous randomized clinical trial. In France, spiramycin (S) is usually prescribed for maternal seroconversions. A more potent pyrimethamine + sulfadiazine (PS) regimen is used to treat congenital toxoplasmosis and is offered in some countries as prophylaxis. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 2, 2018 Category: OBGYN Authors: Laurent Mandelbrot, Fran çois Kieffer, Rémi Sitta, Hélène Laurichesse-Delmas, Norbert Winer, Louis Mesnard, Alain Berrebi, Gwenaëlle Le Bouar, Jean-Paul Bory, Anne-Gaëlle Cordier, Yves Ville, Franck Perrotin, Jean-Marie Jouannic, Florence Biquard, C Tags: Original Research: Obstetrics Source Type: research

Six-month expulsion of postplacental copper intrauterine devices placed after vaginal delivery
Immediate placement of an intrauterine device (IUD) after vaginal delivery is safe and convenient, but longitudinal data describing clinical outcomes have been limited. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 2, 2018 Category: OBGYN Authors: Elizabeth P. Gurney, Sarita Sonalkar, Arden Mcallister, Mary D. Sammel, Courtney A. Schreiber Tags: Original Research: Gynecology Source Type: research

Is there Evidence of a July Effect among Patients Undergoing Hysterectomy Surgery?
It is hypothesized that the quality of health care decreases during trainee turnovers at the beginning of the academic year. The influx of new gynecology and surgery residents into hospitals in this setting may be associated with poorer surgical outcomes, known as the July Effect. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 2, 2018 Category: OBGYN Authors: Sanskriti Varma, Ambar Mehta, Susan Hutfless, Rebecca L. Stone, Stephanie L. Wethington, Amanda N. Fader Tags: Original Research: Gynecology Source Type: research

A prospective cohort study of meat and fish consumption and endometriosis risk
Only two case-control studies have examined the associations between consumption of meat products and endometriosis risk with inconsistent results. Consumption of animal products has the potential to influence endometriosis risk through effects on steroid hormones levels. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 2, 2018 Category: OBGYN Authors: Ayae Yamamoto, Holly R. Harris, Allison F. Vitonis, Jorge E. Chavarro, Stacey A. Missmer Tags: Original Research: Gynecology Source Type: research

Human term amniotic fluid: A novel source of stem cells for regenerative medicine
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 2, 2018 Category: OBGYN Authors: Cara D. Dolin, Michael K. Chan, Ross S. Basch, Bruce K. Young Tags: Research Letter Source Type: research

December 2017 (vol. 217, no. 6, pages 678.e1-9)
Schwebke JR, Morgan FG Jr, Koltun W, et  al. A phase-3, double-blind, placebo-controlled study of the effectiveness and safety of single oral doses of secnidazole 2 g for the treatment of women with bacterial vaginosis. Am J Obstet Gynecol 2017;217:678.e1-9. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 31, 2018 Category: OBGYN Tags: Correction Source Type: research

A rare case of endometriosis invading external iliac vein causing deep vein thrombosis
A 25 year old nulliparous woman presented with a 3 day duration of fever, lower abdominal pain, and shortness of breath. On physical examination, there was a 14 week –sized pelvic mass. A computerized tomography scan showed bilateral multiloculated adnexal masses with compression on the left external iliac vein and a hypodensity within the vein suggesting a thrombus (Figure 1). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 30, 2018 Category: OBGYN Authors: Ma Li, Kailun Chen, Yoke Fai Fong Tags: Images in Gynecology Source Type: research

Clinical and metabolic outcomes in pregnant women at risk for Gestational Diabetes Mellitus supplemented with myo-inositol. A secondary analysis from 3 RCTs
Gestational Diabetes Mellitus (GDM) is defined as carbohydrate intolerance that; begins or it is first recognized during pregnancy. Insulin sensitizing substances as Myo-inositol have been considered for the prevention of GDM and related complications. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 30, 2018 Category: OBGYN Authors: A. Santamaria, A. Alibrandi, A. Di Benedetto, B. Pintaudi, F. Corrado, F. Facchinetti, R. D ’Anna Tags: Original Research Source Type: research

A rare case of endometriosis encasing external iliac vein causing deep vein thrombosis
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 30, 2018 Category: OBGYN Authors: Ma Li, Kailun Chen, Yoke Fai Fong Tags: Images in Gynecology Source Type: research

To the point: gender differences in the obstetrics and gynecology  clerkship
Gender differences in performance on the obstetrics and gynecology clerkship have been reported, with female students outperforming male students. Male students report that their gender negatively affects their experience during the clerkship. Additionally, there are fewer male students applying for obstetric/gynecology residency. This “To The Point” article by the Association of Professors of Gynecology and Obstetrics Undergraduate Medical Education Committee will describe the gender differences that have been found, examine factors that could be contributing to these issues, and propose measures to correct th...
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: LaTasha B. Craig, Samantha D. Buery-Joyner, Susan Bliss, Elise N. Everett, David A. Forstein, Scott C. Graziano, Brittany S. Hampton, Margaret L. McKenzie, Helen Morgan, Sarah M. Page-Ramsey, Archana Pradhan, Laura Hopkins, Undergraduate Medical Education Tags: Expert Review Source Type: research

Reply
We thank Dr Priver for his letter, which raises the issues of quality of life, sexual functioning, subsequent surgery, and cancer risks and asked about our clinical experience. As high-volume surgeons who actively see patients daily, our manuscript is intended to guide best practices, based on the best available data for the removal or conservation of ovaries at the time of hysterectomy. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Marisa R. Adelman, Howard T. Sharp Tags: Letter to the Editors Source Type: research

Removing ovaries at hysterectomy
With regard to the article by Adelman and Sharp,1 I am struck by my sense that their conclusion that ovarian conservation at hysterectomy is better than elective oophorectomy must have been written by people who have spent little time actually listening to and putting their hands on patients. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: David Priver Tags: Letter to the Editors Source Type: research

Extending the safety evidence for opportunistic salpingectomy in prevention of ovarian cancer: A cohort study from British Columbia, Canada
Recent evidence has suggested that the fallopian tube may often be the site of origin for the most common and lethal form of ovarian cancer. As a result, many Colleges of Obstetrics& Gynecology, including ACOG, are recommending surgical removal of the fallopian tube (bilateral salpingectomy) at the time of other gynecologic surgeries (particularly hysterectomy and tubal sterilization) in women at general population risk for ovarian cancer, collectively referred to as opportunistic salpingectomy (OS). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Gillian E. Hanley, Janice S. Kwon, Sarah J. Finlayson, David G. Huntsman, Dianne Miller, Jessica N. McAlpine Tags: Original Research: Gynecology Source Type: research

To the Point: Gender differences in the Obstetrics and Gynecology clerkship
Gender differences in performance on the Obstetrics and Gynecology (Ob/Gyn) clerkship have been reported, with females outperforming males. Males report that their gender negatively affects their experience during the clerkship. Additionally, there are fewer males applying for Ob/Gyn residency. This “To The Point” article by the Association of Professors of Gynecology and Obstetrics (APGO) Undergraduate Medical Education Committee (UMEC) will describe the gender differences that have been found, examine factors that could be contributing to these issues and propose measures to correct these disparities. (Source...
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: LaTasha B. Craig, Samantha D. Buery-Joyner, Susan Bliss, Elise N. Everett, David A. Forstein, Scott C. Graziano, Brittany S. Hampton, Margaret L. Mckenzie, Helen Morgan, Sarah M. Page-Ramsey, Archana Pradhan, Laura Hopkins, Undergraduate Medical Education Tags: Expert Review Source Type: research

Uterine and Cervical Cancer with Irreducible Pelvic Organ Prolapse
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Christopher P. Chung, Stephen J. Lee, Mark T. Wakabayashi Source Type: research

Ovarian Conservation Versus Removal at the Time of Benign Hysterectomy: Reply
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Marisa R. Adelman, Howard T. Sharp Tags: Letter to the Editors Source Type: research

Letter to the Editor “Removing ovaries at hysterectomy”
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: David Priver Tags: Letter to the Editors Source Type: research

Injury-related maternal mortality
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Joel G. Ray, Jonathan Zipursky, Alison L. Park Tags: Research Letter Source Type: research

Is amniotic fluid of women with uncomplicated term pregnancies free of bacteria?
The “sterile womb” paradigm is debated. Recent evidence suggests that the offspring’s first microbial encounter is before birth in term uncomplicated pregnancies. The establishment of a healthy microbiota early in life might be crucial for reducing the burden of diseases later in life. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Eva Maria Rehbinder, Karin C. L ødrup Carlsen, Anne Cathrine Staff, Inga Leena Angell, Linn Landrø, Katarina Hilde, Peter Gaustad, Knut Rudi Tags: Original Research: Obstetrics Source Type: research

Preterm premature rupture of membranes at 22-25 weeks ’ gestation: perinatal and 2-year outcomes within a national population-based study (EPIPAGE-2)
Most clinical guidelines state that with early preterm premature rupture of membranes, obstetric and pediatric teams must share a realistic and individualized appraisal of neonatal outcomes with parents and consider their wishes for all decisions. However, we currently lack reliable and relevant data, according to gestational age at rupture of membranes, to adequately counsel parents during pregnancy and to reflect on our policies of care at these extreme gestational ages. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Elsa Lorthe, H éloïse Torchin, Pierre Delorme, Pierre-Yves Ancel, Laetitia Marchand-Martin, Laurence Foix-L’helias, Valérie Benhammou, Catherine Gire, Claude D’Ercole, Norbert Winer, Loïc Sentilhes, Damien Subtil, François Goffinet, Gilles Kayem Tags: Original Research: Obstetrics Source Type: research

Prospective chromosome analysis of 3429 amniocentesis samples in China using copy number variation sequencing
Next generation sequencing (NGS) is emerging as a viable alternative to chromosome microarray analysis for the diagnosis of chromosome disease syndromes. One NGS methodology, copy number variation sequencing (CNV-Seq), has been shown to deliver high reliability, accuracy and reproducibility for detection of fetal CNVs in prenatal samples. However, its clinical utility as a first tier diagnostic method has yet to be demonstrated in a large cohort of pregnant women referred for fetal chromosome testing. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 28, 2018 Category: OBGYN Authors: Jing Wang, Lin Chen, Cong Zhou, Li Wang, Hanbin Xie, Yuanyuan Xiao, Hongmei Zhu, Ting Hu, Zhu Zhang, Qian Zhu, Zhiying Liu, Shanlin Liu, He Wang, Mengnan Xu, Zhilin Ren, Fuli Yu, David S. Cram, Hongqian Liu Source Type: research

Perinatal anxiety: approach to diagnosis and management in the obstetric  setting
Anxiety is common in women during the perinatal period, manifests with various symptoms and severity, and is associated with significant maternal morbidity and adverse obstetric and neonatal outcomes. Given the intimate relationship and frequency of contact, the obstetric provider is positioned optimally to create a therapeutic alliance and to treat perinatal anxiety. Time constraints, absence of randomized controlled trials, mixed quality of data, and concern for potential adverse reproductive outcomes all limit the clinician ’s ability to initiate informed risk-benefit discussions. (Source: American Journal of Obst...
Source: American Journal of Obstetrics and Gynecology - May 24, 2018 Category: OBGYN Authors: Katie R. Thorsness, Corey Watson, Elizabeth M. Larusso Tags: Expert Review Source Type: research

Fetal Growth Velocity: the NICHD Fetal Growth Studies
Accurately identifying pregnancies with accelerated or diminished fetal growth is challenging and generally based on cross-sectional percentile estimates of fetal weight. Longitudinal growth velocity might improve identification of abnormally grown fetuses. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 24, 2018 Category: OBGYN Authors: Katherine L. Grantz, Sungduk Kim, William A. Grobman, Roger Newman, John Owen, Daniel Skupski, Jagteshwar Grewal, Edward K. Chien, Deborah A. Wing, Ronald J. Wapner, Angela C. Ranzini, Michael P. Nageotte, Stefanie N. Hinkle, Sarah Pugh, Hanyun Li, Karin Tags: Original Research: Obstetrics Source Type: research

Perinatal Anxiety: Approach to Diagnosis & Management in the Obstetric Setting
Anxiety is common in women during the perinatal period, manifests with various symptomatology and severity, and is associated with significant maternal morbidity and adverse obstetrical and neonatal outcomes. Given the intimate relationship and frequency of contact, the obstetric provider is optimally positioned to create a therapeutic alliance and manage perinatal anxiety. Time constraints, absence of randomized controlled trials, mixed quality of data, and concern for potential adverse reproductive outcomes all limit clinicians' ability to initiate informed risk-benefit discussions. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 24, 2018 Category: OBGYN Authors: Katie R. Thorsness, Corey Watson, Elizabeth M. Larusso Tags: Expert Review Source Type: research

Electronic fetal monitoring or cardiotocography, 50 years later: what's  in a name?
Almost 350 years ago, fetal heart sounds were first described by the French physician Marsac, but it took another 150 years before fetal auscultation using mechanical stethoscopes entered routine clinical practice in western Europe and North America.1 (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Authors: Diogo Ayres-de-Campos Tags: Editorial Source Type: research

Pain relief: determining the safety of ibuprofen with postpartum preeclampsia
Hypertensive disorders effect up to 10% of pregnancies.1 They are a significant contributor to maternal and perinatal morbidity and mortality worldwide.2 Hypertensive disease that originates or persists into the postpartum period contributes to prolonged hospitalizations and hospital readmissions.3 Presence of these conditions in the peripartum period has also been linked to lifelong cardiovascular risk.4 (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Authors: Jonathan S. Hirshberg, Alison G. Cahill Tags: Editorial Source Type: research

Table of Contents
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Source Type: research

Information for Readers
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Source Type: research

Neonatal outcomes of elective early-term births after demonstrated fetal lung maturity
Studies of early-term birth after demonstrated fetal lung maturity show that respiratory and other outcomes are worse with early-term birth (370 –386 weeks) even after demonstrated fetal lung maturity when compared with full-term birth (390–406 weeks). However, these studies included medically indicated births and are therefore potentially limited by confounding by the indication for delivery. Thus, the increase in adverse outcomes might be due to the indication for early-term birth rather than the early-term birth itself. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Authors: Alan T.N. Tita, Kathleen A. Jablonski, Jennifer L. Bailit, William A. Grobman, Ronald J. Wapner, Uma M. Reddy, Michael W. Varner, John M. Thorp, Kenneth J. Leveno, Steve N. Caritis, Jay D. Iams, George Saade, Yoram Sorokin, Dwight J. Rouse, Sean C. Blackw Tags: Original Research Source Type: research

Reply
We would like to thank Dr Middelkoop and Dr Huirne for their comments related to our recent publication.1 Their letter raises several issues that we would like to address. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Authors: Sukhbir S. Singh, Liane Belland, Nicholas Leyland, Sarah von Riedemann, Ally Murji Tags: Letter to the Editors Source Type: research

Neonatal Outcomes of Elective Early Term Births after Demonstrated Fetal Lung Maturity
Studies of early term birth after demonstrated fetal lung maturity show that respiratory and other outcomes are worse with early term birth (370-386) even after demonstrated fetal lung maturity when compared with full term birth (390-406). However these studies included medically indicated births and are therefore potentially limited by confounding by the indication for delivery. Thus the increase in adverse outcomes might be due to the indication for early term birth rather than the early term birth itself. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Authors: Alan T.N. Tita, Kathleen A. Jablonski, Jennifer L. Bailit, William A. Grobman, Ronald J. Wapner, Uma M. Reddy, Michael W. Varner, John M. Thorp, Kenneth J. Leveno, Steve N. Caritis, Jay D. Iams, George Saade, Yoram Sorokin, Dwight J. Rouse, Sean C. Blackw Tags: Original Research: Obstetrics Source Type: research

Re: The past, present, and future of selective progesterone receptor modulators in the management of uterine fibroids
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 22, 2018 Category: OBGYN Authors: Mei-An Middelkoop, Judith A.F. Huirne Tags: Letter to the Editors Source Type: research