Giants in Obstetrics and Gynecology Series: a profile of Linda C. Giudice, MD, PhD, MSc
Linda C. Giudice, MD, PhD, MSc, is Distinguished Professor, Chair Emerita, and the Robert B. Jaffe, MD, Endowed Professor in the Reproductive Sciences at the University of California, San Francisco (UCSF). Dr Giudice has conducted pioneering research in endocrinology of the endometrium, and she has made major contributions to our understanding of the biology of the menstrual cycle, thus laying the foundation for the implementation of precision medicine in reproductive disorders involving the endometrium. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 29, 2021 Category: OBGYN Authors: Roberto Romero Tags: Giants in Obstetrics and Gynecology Source Type: research

Table of Contents
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 29, 2021 Category: OBGYN Source Type: research

Information for readers
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 29, 2021 Category: OBGYN Source Type: research

AJOG MFM Table of Contents
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 29, 2021 Category: OBGYN Source Type: research

SMFM Fetal Anomalies Consult Series #4: Genitourinary Anomalies
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 27, 2021 Category: OBGYN Authors: Society for Maternal-Fetal Medicine (SMFM), Mary E. Norton, Yvonne Cheng, Shilpa Chetty, Jacquelyn K. Chyu, Katherine Connolly, Neda Ghaffari, Linda M. Hopkins, Angie Jelin, Anne Mardy, Sarah S. Osmundson, Teresa N. Sparks, Jeffrey Sperling, Kate Swanson, Tags: SMFM Consult Series Source Type: research

Coagulation assessment with viscoelastic testing in asymptomatic post-partum patients with SARS-CoV-2 infection: a pilot study
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 27, 2021 Category: OBGYN Authors: Luis D. PACHECO, Marissa BERRY, Antonio F. SAAD, Sean G. YATES, George R. SAADE Tags: Research Letter Source Type: research

Neonatal morbidity and mortality by mode of delivery in very preterm neonates
The safest mode of delivery for very preterm infants is an ongoing topic of debate. There are many reasons for cesarean delivery (CD) in extremely preterm and very preterm infants, including labor, fetal distress, maternal indications, and malpresentation. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 27, 2021 Category: OBGYN Authors: Leilah D. Zahedi-Spung, Nandini Raghuraman, George A. Macones, Alison G. Cahill, Joshua I. Rosenbloom Tags: Original Research: Obstetrics Source Type: research

Exome sequencing versus targeted gene panels for the evaluation of nonimmune hydrops fetalis
Next generation sequencing is increasingly used in prenatal diagnosis. Targeted gene panels and exome sequencing are both available, but the comparative diagnostic yields of these approaches are not known. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 27, 2021 Category: OBGYN Authors: Mary E. NORTON, Jessica VAN. ZIFFLE, Billie R. LIANOGLOU, Ugur HODOGLUGIL, W. Patrick DEVINE, Teresa N. SPARKS Tags: Original Research: Obstetrics Source Type: research

Association between pregnancy and long-term cardiac outcomes in women with congenital heart disease
As early life interventions for congenital heart disease (CHD) improve, more patients are living to adulthood and considering pregnancy. Scoring and classification systems predict maternal cardiovascular risk of pregnancy in the context of congenital heart disease but these scoring systems do not assess the potential subsequent risks following pregnancy. Data on long-term cardiac outcomes after pregnancy are unknown for most lesion types. This limits healthcare practitioners ’ ability to thoroughly counsel patients considering pregnancy in the setting of congenital heart disease. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 27, 2021 Category: OBGYN Authors: Shannon L. SON, Lauren L. HOSEK, Miranda C. STEIN, Amanda A. ALLSHOUSE, Anna B. CATINO, Arvind K. HOSKOPPAL, Daniel A. COX, Kevin J. WHITEHEAD, Ian M. LINDSAY, Sean ESPLIN, Torri D. METZ Tags: Original Research: Obstetrics Source Type: research

SMFM Special Statement: Surgical Safety Checklists for Cesarean Delivery
The routine use of surgical safety checklists can reduce perioperative complications. Generic surgical checklists are insufficient for cesarean delivery because each cesarean delivery involves two patients (mother and fetus/newborn), each with separate care teams and health and safety considerations. To address the added complexity of care coordination and communication inherent in cesarean delivery, the Society for Maternal-Fetal Medicine presents example standard surgical safety checklists for cesarean surgery that include elements of care for both the mother and newborn. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 26, 2021 Category: OBGYN Authors: Patient Safety and Quality Committee, Society for Maternal-Fetal Medicine, C. Andrew Combs, Brett D. Einerson, Lorraine E. Toner Tags: SMFM Statement Source Type: research

SARS-COV-2 infection during pregnancy and risk of preeclampsia: a systematic review and meta-analysis
To examine the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and the risk of preeclampsia. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 20, 2021 Category: OBGYN Authors: Agustin Conde-Agudelo, Roberto Romero Tags: Systematic Review Source Type: research

Association Between the Urogenital Microbiome and Surgical Treatment Response in Women Undergoing Mid-urethral Sling Surgery for Mixed Urinary Incontinence
The urogenital microbiome is associated with urgency and mixed urinary incontinence symptoms and differential treatment response to pharmacotherapy for urgency urinary incontinence. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 20, 2021 Category: OBGYN Authors: Holly E. Richter, Megan U. Carnes, Yuko M. Komesu, Emily S. Lukacz, Lily Arya, Megan Bradley, Rebecca G. Rogers, Vivian W. Sung, Nazema Y. Siddiqui, Benjamin Carper, Donna Mazloomdoost, Darryl Dinwiddie, Marie G. Gantz, NICHD Pelvic Floor Disorders Networ Tags: Original Research: Gynecology Source Type: research

Underestimation of SARS-CoV-2 infection in placental samples
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 20, 2021 Category: OBGYN Authors: Nazeeh HANNA, Xinhua LIN, Kristen THOMAS, Anthony VINTZILEOS, Martin CHAVEZ, Thomas PALAIA, Louis RAGOLIA, Sourabh VERMA, Poonam KHULLAR, Iman HANNA Tags: Research Letter Source Type: research

Trajectories of antenatal depression and adverse pregnancy outcomes
Antenatal depression affects approximately one in seven pregnancies, with an increasing prevalence across gestation. Data regarding the associations between antenatal depression and adverse pregnancy outcomes yield conflicting results. However, previous studies evaluated the cross-sectional prevalence of depression at various time points, and not the trajectory of depressive symptoms across gestation. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 16, 2021 Category: OBGYN Authors: Emily S. MILLER, George R. SAADE, Hyagriv N. SIMHAN, Catherine MONK, David M. HAAS, Robert M. SILVER, Brian M. MERCER, Samuel PARRY, Deborah A. WING, Uma M. REDDY, William A. GROBMAN Tags: Original Research: Obstetrics Source Type: research

Human papillomavirus vaccination history and diagnosis of cervical intraepithelial neoplasia grade 2 or more severe lesions among a cohort of colposcoped women in Kaiser Permanente Southern California
Risk of a high-grade lesion in women undergoing colposcopy following an abnormal screening result may be different by human papillomavirus (HPV) vaccination status, since vaccinated women are presumably less likely to harbor HPV 16 and 18. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 14, 2021 Category: OBGYN Authors: Neal M. Lonky, Lanfang Xu, Diane M. Dasilva, Juan C. Felix, Chun Chao Tags: Original Research: Gynecology Source Type: research

Association between COVID-19 infection at the time of admission for birth and adverse pregnancy outcomes: evolving evidence to aid decision-making
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 12, 2021 Category: OBGYN Authors: Jan VAN DER MEULEN, Asma KHALIL Source Type: research

Endometrioma surgery - A systematic review and meta-analysis of the effect on antral follicle count and anti-M üllerian hormone
Accurate pre-operative counseling regarding whether endometriotic cystectomy has a detrimental effect on the ovarian reserve has been a considerable challenge, as studies assessing antral follicle counts (AFC) and anti-M üllerian hormone (AMH) levels have reported conflicting results. Our objective was to explore the impact of endometriotic cystectomy on both AMH and AFC measurements, but focusing on prospective studies where both were measured for each woman concurrently (overcoming unmeasured confounding), in the same setting (overcoming surgical technique differences) and at the same three postoperative time points...
Source: American Journal of Obstetrics and Gynecology - July 12, 2021 Category: OBGYN Authors: Johnny S. Younis, Nora Shapso, Yval Ben-Sira, Scott M. Nelson, Ido Izhaki Tags: Systematic Review Source Type: research

Reply: Why does fetal head rotation occur in spontaneous labor?
We appreciate the interest shown by Drs Ross and Gemert in our recent publication on the ultrasound study of fetal head rotation during spontaneous labor in nulliparous women.1 The combined use of transabdominal and transperineal ultrasound methods opens up a new and more detailed way of studying the rotation of the fetal head, including the possible effects of epidural analgesia on this mechanism. The points specifically raised in the letter considered the effect epidural analgesia may have on the pelvic floor, relaxing the muscles and thereby, reducing the resistance provided by the pelvic floor. (Source: American Journa...
Source: American Journal of Obstetrics and Gynecology - July 9, 2021 Category: OBGYN Authors: Hulda Hjartard óttir, Torbjørn M. Eggebø Tags: Letter to the Editors Source Type: research

Unindicated Cervical Cancer Screening in Adolescent Females within a Large Healthcare System in the United States
Current consensus recommendations are to not initiate cervical cancer screening for immunocompetent adolescent females prior to age 21 years. This is in part due to very low rate of 0.8 per 100,000 new cervical cancer cases diagnosed among women ages 20 to 24 years. Timely HPV vaccination further decreases incidence of cervical cancer to 4 cases per 100,000 persons by the age of 28 years. Screening prior to age 21 has demonstrated no clear benefit in cancer risk reduction or outcomes. Additionally, unindicated screening among adolescents can lead to patient harm and increasing cost to the healthcare system. (Source: Americ...
Source: American Journal of Obstetrics and Gynecology - July 9, 2021 Category: OBGYN Authors: Hillary Hosier, Sangini S. Sheth, Carlos R. Oliveira, Lauren E. Perley, Alla Vash-Margita Tags: Original Research: Gynecology Source Type: research

Why does fetal head rotation occur in spontaneous labor?
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 9, 2021 Category: OBGYN Authors: Michael G. ROSS, Martin J.C. van GEMERT Tags: Letter to the Editors Source Type: research

Why does fetal head rotation occur in spontaneous labor?: reply
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 9, 2021 Category: OBGYN Authors: Hulda HJARTARDOTTIR, Torbj ørn M. EGGEBØ Source Type: research

Blastocyst morphology is associated with the incidence of monozygotic twinning in assisted reproductive technology
An increased incidence of monozygotic twinning following blastocyst transfer has been previously reported in assisted reproductive technology treatment. It is uncertain whether this phenomenon is due to the extended culture time, culture medium, or inherent blastocyst parameters. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 7, 2021 Category: OBGYN Authors: Wenhao Shi, Lei Jin, Jiayin Liu, Cuilian Zhang, Yang Mi, Juanzi Shi, Hui Wang, Xiaoyan Liang Tags: Original Research: Gynecology Source Type: research

Placenta Accreta Spectrum Treatment with Intraoperative Multivessel Embolization: The PASTIME Protocol
Multidisciplinary care for placenta accreta spectrum (PAS) improves pregnancy outcomes, but the specific components of such multidisciplinary collaboration varies between institutions. As experience with PAS increases, assessing new surgical techniques and protocols is crucial to help improve maternal outcomes and to advocate for hospital resources. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 7, 2021 Category: OBGYN Authors: Dora J. Melber, Zachary T. Berman, Marni B. Jacobs, Andrew C. Picel, Charlotte L. Conturie, Kathy Zhang-Rutledge, Pratibha S. Binder, Ramez N. Eskander, Anne C. Roberts, Michael T. Mchale, Gladys A. Ramos, Jerasimos Ballas, Thomas F. Kelly Tags: Meeting Papers: SMFM Papers Source Type: research

Preterm Labor is a Distinct Process from Term Labor following Computational Analysis of Human Myometrium.
The onset of term human parturition involves myometrial gene expression changes to transform the uterus from a quiescent to a contractile phenotype. It is uncertain whether the same changes occur in the uterus during preterm labor. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 7, 2021 Category: OBGYN Authors: Jason Phung, Carol Wang, Jocelyn Reeders, Eng-Cheng Chan, Carlos Riveros, Tamas Zakar, Jonathan W. Paul, Craig Pennell, Roger Smith Tags: Original Research: Obstetrics Source Type: research

Postpartum preeclampsia or eclampsia: defining its place and management among the  hypertensive disorders of pregnancy
High blood pressure in the postpartum period is most commonly seen in women with antenatal hypertensive disorders, but it can develop de novo in the postpartum time frame. Whether postpartum preeclampsia or eclampsia represents a separate entity from preeclampsia or eclampsia with antepartum onset is unclear. Although definitions vary, the diagnosis of postpartum preeclampsia should be considered in women with new-onset hypertension 48 hours to 6 weeks after delivery. New-onset postpartum preeclampsia is an understudied disease entity with few evidence-based guidelines to guide diagnosis and management. (Source: American J...
Source: American Journal of Obstetrics and Gynecology - July 6, 2021 Category: OBGYN Authors: Alisse Hauspurg, Arun Jeyabalan Tags: Expert Review Source Type: research

Cost Effectiveness of Behavioral and Pelvic Floor Muscle Therapy Combined With Midurethral Sling Surgery vs Surgery Alone Among Women With Mixed Urinary Incontinence: Results of the ESTEEM Randomized Trial
Urinary incontinence is prevalent among women, and it has a significant economic impact. Mixed urinary incontinence, with both stress and urgency urinary incontinence, has a greater adverse impact on quality of life and is more complex to treat compared to either stress or urgency urinary incontinence alone. Studies evaluating the cost-effectiveness of treating both the stress and urgency components simultaneously are lacking. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 6, 2021 Category: OBGYN Authors: Heidi S. Harvie, Vivian W. Sung, Simon J. Neuwahl, Amanda A. Honeycutt, Isuzu Meyer, Christopher J. Chermansky, Shawn Menefee, Whitney K. Hendrickson, Gena C. Dunivan, Donna Mazloomdoost, Sarah J. Bass, Marie G. Gantz, NICHD Pelvic Floor Disorders Network Tags: Original Research: Gynecology Source Type: research

Microvascular placental alterations in a maternal COVID-19 infection
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 3, 2021 Category: OBGYN Authors: Maximilian Ackermann, Danny D. Jonigk Tags: Images in Obstetrics Source Type: research

Women ’s Preventive Services Initiative: Fertility counseling overlooked
The 2021 Women ’s Preventive Services Initiative (WPSI) Well Woman Chart outlines a framework for incorporating preventive health services recommended by the WPSI, U.S. Preventive Services Task Force (USPSTF), and Bright Futures based on age, health status, and risk factors. In accordance with previous guideline s for preventive care, this document fails to offer recommendations or guidelines for infertility screening and fertility counseling in the course of well-woman care. Healthcare providers may be less likely to address fertility with their patients in the absence of clear, evidence-based recommendati ons, pote...
Source: American Journal of Obstetrics and Gynecology - July 3, 2021 Category: OBGYN Authors: Jennifer B. BAKKENSEN, Kara N. GOLDMAN Tags: Clinical Opinion Source Type: research

"Dr Isaac Schiff, Professor and Chair of the Vincent Department of Obstetrics and Gynecology at Massachusetts General Hospital/Harvard Medical School reopens the Obstetrical Service closed since the Second World War
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 2, 2021 Category: OBGYN Authors: Roberto Romero Tags: Letter to the Editors Source Type: research

Association of pharmacist prescription and 12-month contraceptive continuation rates
States have passed legislation to expand the scope of pharmacists to directly prescribe contraception. It is thought that pharmacist prescription of contraception may promote correct and consistent use of contraception by reducing barriers to access. However, it is not known how this may impact ongoing contraceptive use. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Maria I. Rodriguez, Megan Skye, Alison B. Edelman, Lorinda Anderson, Blair G. Darney Tags: Original Research Source Type: research

A partial salpingectomy paper should not be considered in a meta-analysis for salpingectomy
I read with great interest the systematic review and meta-analysis by Mills et  al1 on salpingectomy vs tubal ligation for sterilization. The authors refer to Committee Opinion number 774, in which salpingectomy is described as removal of the tube completely from its fimbriated end up to the uterotubal junction.2 However, the authors include in the studies (Table) a study by Rodriguez et al3 that compares partial salpingectomy with bilateral tubal ligation. They also present data on the risk of postoperative pregnancy (Figure 9), and they do not specify in the text that this refers to partial salpingectomy. ...
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Miltiadis Pitsos Tags: Letter to the Editors Source Type: research

Efficacy of combined oral contraceptives for depressive symptoms and overall symptomatology in premenstrual syndrome: pairwise and network meta-analysis of randomized trials
Combined oral contraceptives are often considered a treatment option for women with premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) also seeking contraception, but evidence for this treatment is scarce. We aimed to determine 1) the level of evidence for the efficacy of combined oral contraceptives in managing premenstrual depressive symptoms and overall premenstrual symptomatology, and 2) the comparative efficacy of combined oral contraceptives (PROSPERO registration number CRD42020205510). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Anouk E. DE WIT, Ymkje Anna DE VRIES, Marrit K. DE BOER, Celeste SCHEPER, Ante FOKKEMA, Catharina AH. JANSSEN, Erik J. GILTAY, Robert A. SCHOEVERS Tags: Systematic Review Source Type: research

Association between peripartum hysterectomy and venous thromboembolism
The risk of venous thromboembolism (VTE) postpartum is modified by mode of delivery, with the risk of VTE being higher after cesarean compared to vaginal delivery. The risk of VTE following peripartum hysterectomy is largely unknown. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Logan C. MAUNEY, William H. BARTH, Mark A. CLAPP Tags: Original Research: Obstetrics Source Type: research

The Optimal Strategy for Pertussis Vaccination: A Systematic Review and Meta-analysis of Randomized Control Trials and Real-World Data
Severe pertussis infection has been reported in infants prior to receiving routine immunization series. This problem could be solved by vaccinating mothers during pregnancy or children at birth. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Hung Song Nguyen, Nguyen-Phong Vo, Shih-Yen Chen, Ka-Wai Tam Tags: Systematic Review Source Type: research

“A partial salpingectomy paper should not be considered in a meta-analysis for salpingectomy.”
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Miltiadis Pitsos Tags: Letter to the Editors Source Type: research

Association of pharmacist prescription and 12 month contraceptive continuation rates
States have passed legislation to expand the scope of pharmacists to directly prescribe contraception. It is thought that pharmacist prescription of contraception may promote correct and consistent use of contraception, by reducing barriers to access. However,it is not known how this may impact ongoing contraceptive use. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Maria I. RODRIGUEZ, Megan SKYE, Alison B. EDELMAN, Lorinda ANDERSON, Blair G. DARNEY Tags: Original Research: Gynecology Source Type: research

Neonatal Outcomes of Births in Freestanding Birth Centers and Hospitals in the United States 2016-2019
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 1, 2021 Category: OBGYN Authors: Amos Gr ünebaum, Laurence B. McCullough, Eran Bornstein, Erez Lenchner, Adi Katz, Lisa B. Spiryda, Risa Klein, Frank A. Chervenak Tags: Original Research: Obstetrics Source Type: research

Obstetrical, fetal, and lactation pharmacology —a crisis that can no longer be ignored
The data available to inform pregnant and lactating women about drug safety and efficacy are woefully inadequate. This lack of information encompasses every aspect of pharmaceutics, including limited human data about the embryonic risk, limited pharmacokinetic and pharmacodynamic information during and after pregnancy to ensure proper dosing, and a dearth of new medications to treat obstetrical and lactation disorders. This state of affairs has been longstanding and can be attributed to several realities, most of which have withstood any efforts to modify them. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Authors: Steve N. Caritis, Raman Venkataramanan Tags: Expert Reviews Source Type: research

Prescription medications for use in pregnancy –perspective from the US Food and Drug Administration
Obstetrical healthcare providers frequently field questions about the safety of medications recommended or prescribed to their pregnant patients. Most women use as least 1 medication during pregnancy; however, there is little information about the safety or appropriate dosing of many medications during this phase of life. In addition, the development of drugs for use in pregnant women trails behind the development of drugs intended for other sectors of the population. Our goal is to inform the obstetrics community about the US Food and Drug Administration authority and their role in approving drugs for marketing. (Source: ...
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Authors: Barbara D. Wesley, Catherine A. Sewell, Christina Y. Chang, Kimberly P. Hatfield, Christine P. Nguyen Tags: Expert Reviews Source Type: research

Women and babies are dying from inertia: a collaborative framework for obstetrical drug development is urgently needed
Obstetrical complications, often referred to as the “great obstetrical syndromes,” are among the most common global causes of mortality and morbidity in young women and their infants. However, treatments for these syndromes are underdeveloped compared with other fields of medicine and are urgently needed. This current paucity of treatments for ob stetrical complications is a reflection of the challenges of drug development in pregnancy. The appetite of pharmaceutical companies to invest in research for obstetrical syndromes is generally reduced by concerns for maternal, fetal, and infant safety, poor definition...
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Authors: Edith Roset Bahmanyar, Henk J. Out, Marcel van Duin Tags: Clinical Opinion Source Type: research

Table of Contents
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Source Type: research

Information for Readers
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Source Type: research

AJOG MFM Table of Contents
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Source Type: research

SMFM Divider Page
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Source Type: research

The incorporation of telehealth in high-risk pregnancy follow-up needs tailored optimized care scheduled in a strict care protocol
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Authors: L. Carbillon, A. Benbara, M. Fermaut Tags: Letter to the Editors Source Type: research

Reply to: The incorporation of telehealth in high-risk pregnancy follow-up needs tailored optimized care scheduled in a strict care protocol
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Authors: Alex F. PEAHL, Michelle H. MONIZ Tags: Letter to the Editors Source Type: research

Misclassification bias and unnecessary anxiety
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Authors: Marian KNIGHT, Elizabeth DRAPER, Jennifer J. KURINCZUK, MBRRACE-UK Tags: Letter to the Editors Source Type: research

Perinatal outcomes after bariatric surgery
Bariatric surgery is a widespread treatment for obesity that often provides long-term weight control and health benefits. Although a growing number of women are becoming pregnant after bariatric surgery, few population-based studies have assessed its impact on perinatal outcomes. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 30, 2021 Category: OBGYN Authors: Darios Getahun, Michael J. Fassett, Steven J. Jacobsen, David A. Sacks, Sameer B. Murali, Morgan R. Peltier, Wudeneh Mulugeta, Vicki Y. Chiu, Deborah A. Wing, Karen J. Coleman Tags: Original Research: Obstetrics Source Type: research

Reply to a question regarding ovarian cancer prevention with partial salpingectomy vs complete
Dr Pitsos brings up a good point that has already been answered, at least partially, in the literature.1 Several studies, most notably Lessard-Anderson et  al,2 have shown that a partial salpingectomy, or even just a distal fimbriectomy, does reduce the risk of epithelial ovarian cancer more than nonexcising procedures. Clearly, this begs the next question, which is how much of the tube needs to be removed to gain this advantage. Although it is true that Committee Opinion 7743 does recommend removal up to the uterotubal junction, the opinion acknowledges that there are interstitial portions of the tube that will not b...
Source: American Journal of Obstetrics and Gynecology - June 29, 2021 Category: OBGYN Authors: Greg Marchand, Kerry Mills, Kelly Ware Tags: Letter to the Editors Source Type: research

Reply to a question regarding ovarian cancer prevention with partial salpingectomy versus complete.
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 29, 2021 Category: OBGYN Authors: Greg Marchand, Kerry Mills, Kelly Ware Source Type: research