The predictive and diagnostic ability of IL-6 for postoperative urosepsis in patients undergoing percutaneous nephrolithotomy
AbstractThe aim of this study is to investigate the predictive and diagnostic ability of interleukin-6 (IL-6) for postoperative urosepsis in patients undergoing percutaneous nephrolithotomy (PCNL). 90 patients undergoing PCNL between April 2019 and September 2019 were studied. 16 patients progressed to urosepsis (EXP1 group,n = 16) and 74 patients did not (CON group,n = 74); demographic and perioperative data were compared between these two groups. 25 patients who progressed to postoperative urosepsis without receiving the test of IL-6 between March 2018 and March 2019 were enrolled (EXP2 group,...
Source: Urolithiasis - January 13, 2021 Category: Urology & Nephrology Source Type: research

How does pre-operative antimicrobial treatment influence the intra-operative culture results and infectious complications in patients with positive baseline bladder urine culture undergoing ureteroscopic lithotripsy?
We examined intra-operative cultures (ICs), including bladder urine culture, renal pelvic urine culture and stone culture, in all cases. We studied the association between the results of PBUC, ICs and infectious complications in both groups. A total of 67 and 95 patients had positive and negative PBUC, respectively. In the positive PBUC group, 19 (28.4%) patients still had positive bladder urine culture after the antibiotic treatment. Positive ICs (43.3% vs. 3.2%,p 
Source: Urolithiasis - January 11, 2021 Category: Urology & Nephrology Source Type: research

Effect of parathyroidectomy on renal stone recurrence
AbstractParathyroidectomy (PTX) is routinely performed in hypercalciuric renal stone patients with primary hyperparathyroidism (PHPT). However, some data indicate a persistent stone activity following PTX, raising the issue of the link between PHPT and stone disease. We performed an observational study on 30 renal stone patients diagnosed with PHPT. Patients were selected among 1448 hypercalciuric patients referred in our department for a diagnostic evaluation. Patients with no parathyroid surgery or any biological follow-up were excluded. Clinical and biological data (including 24-h urine collection and a calcium load tes...
Source: Urolithiasis - January 9, 2021 Category: Urology & Nephrology Source Type: research

Can ultrasound guidance reduce radiation exposure significantly in percutaneous nephrolithotomy in pediatric patients?
In this study, we aimed to compare clinical and technical outcomes between pediatric patients who underwent percutaneous nephrolithotomy (PCNL) under fluoroscopy (FL) and those that underwent this procedure under FL with ultrasound assistance (FLUSA). The data of 66 PCNL patients were analyzed retrospectively. Renal puncture was successful in 22 patients in the FLUSA group and 44 patients in the FL group. In all cases, FL was used for tract dilation and confirmation of ureteral catheter positioning at the beginning of the procedure. The sample consisted of 46 males and 20 females with a mean age of 7.2  ±&thi...
Source: Urolithiasis - January 8, 2021 Category: Urology & Nephrology Source Type: research

The impact of the number of lifetime stone events on quality of life: results from the North American Stone Quality of Life Consortium
AbstractTo evaluate the impact of chronic stone recurrence on an individual ’s quality of life using the validated Wisconsin Stone Quality of Life (WISQOL) questionnaire. We collected cross-sectional data on patients with kidney stones from 14 institutions in North America. A stone event was defined as renal colic, stone-related procedure or emergency department visit. Th e regression analyses using general linear models and pairwise comparison determined the impact of the number of stone events on quality of life. The median number of stone events among the 2205 patients who completed the questionnaire was 3 (IQR 1&...
Source: Urolithiasis - January 6, 2021 Category: Urology & Nephrology Source Type: research

Correction to: Is health ‑related quality of life of patients after single‑use flexible ureteroscopy superior to extracorporeal shock wave lithotripsy? A randomised prospective study
The original article can be found online. (Source: Urolithiasis)
Source: Urolithiasis - January 5, 2021 Category: Urology & Nephrology Source Type: research

The Comprehensive Complication Index (CCI) for improved reporting of complications in endourological stone treatment
AbstractThe Clavien-Dindo Classification (CDC) lacks a combined score of multiple complications in one patient. The comprehensive complication index (CCI) circumvents this problem making it a valuable instrument to optimize quality control. We aimed to introduce and validate CCI in the treatment of urolithiasis. 60  day postoperative complications of 327 consecutive patients undergoing percutaneous nephrolitholapaxy (PNL) and ureterorenoscopy (URS) between 2017 and 2019 were retrospectively assessed and graded according to CDC. CCI was calculated for each patient. Overall morbidity scores of CCI and CDC were compared....
Source: Urolithiasis - January 3, 2021 Category: Urology & Nephrology Source Type: research

Predictive value of ureteral wall thickness (UWT) assessment on the success of internal ureteral stent insertion in cases with obstructing ureteral calculi
AbstractTo evaluate the possible role of ureteral wall thickness (UWT) assessment in the prediction of the success for stent placement in cases with obstructing ureteric stones. 227 adult patients with a single unilateral obstructing ureteral stone requiring internal ureteral stent placement were included. In addition to stone size, the ureteric wall thickness at the impacted stone site and the degree of hydronephrosis were also assigned on CT images. Patients were divided into two subgroups: Group 1: patients in whom internal ureteral stent could not be passed beyond the stone and Group 2: patients in whom an internal ure...
Source: Urolithiasis - January 2, 2021 Category: Urology & Nephrology Source Type: research

Association between time to lithotripsy and stone-free rate in patients with ureteral stones undergoing shock wave lithotripsy
In conclusion, time to lithotripsy is a strong predictive factor for stone-free status following shock wave lithotripsy. Urgent shock wave lithotripsy did not improve stone-free rate if performed within 1 month. However, time to shock wave litho tripsy >  2 months reduced likelihood of stone-free status. (Source: Urolithiasis)
Source: Urolithiasis - January 2, 2021 Category: Urology & Nephrology Source Type: research

LITHORISK.COM: the novel version of a software for calculating and visualizing the risk of renal stone
AbstractEstimation of state of saturation with stone-forming salt represents a reliable tool to assess the overall risk. The available methods are based on computer-assisted ab initio calculations. Our earlier method URSUS was subsequently substituted by Lithorisk ®, a software including visualization of risk profiles. Unfortunately, Lithorisk does not adapt to new versions of Windows® and Macintosh® Apple, neither runs on smartphones or tablets. We propose a novel version of the software which can be directly used online on any device equipped by differen t operating systems. Upon online connection and after r...
Source: Urolithiasis - November 27, 2020 Category: Urology & Nephrology Source Type: research

Modifications regarding diagnostic approach and therapeutic management of urinary stones ’ disorders during COVID-19 pandemic
(Source: Urolithiasis)
Source: Urolithiasis - November 18, 2020 Category: Urology & Nephrology Source Type: research

Does antibiotic use explain the discrepancy of urolithiasis prevalence between countries?
(Source: Urolithiasis)
Source: Urolithiasis - November 16, 2020 Category: Urology & Nephrology Source Type: research

Klotho gene polymorphism in renal stone formers from Northwestern India
AbstractKlotho gene is an important gene involved in calcium homeostasis, and polymorphisms of this gene may render the individual prone to renal stone formation. We evaluated G395A single nucleotide polymorphisms (SNPs) of Klotho gene at rs1207568 in renal stone patients of North India. This was a prospective study involving 150 patients of renal stone disease (aged 15 –60 years) and 100 age- and sex-matched controls. The DNA was isolated and subjected to polymerase chain reaction (PCR) for identifying the G395A Klotho SNPs at rs1207568. Confronting two pair primers were used, and gel electrophoresis showing tw...
Source: Urolithiasis - November 11, 2020 Category: Urology & Nephrology Source Type: research

Ultra-mini flexible percutaneous nephrolithotomy in the treatment of moderate-size kidney stones: a new instrument, a preliminary prospective study
AbstractUltra-mini PNL is increasingly preferred in the treatment of kidney stones. Unlike routine applications of the ultra-mini PNL technique, we aimed to perform kidney stones treatment with an epiduroscopic device that can pass through 11 –13-Fr ureteral access sheaths with a flexible structure and which is routine in neurosurgical practice. The study was planned prospectively. The study included 52 patients with mid-sized kidney stones who had presented to our clinic between July 2017 and January 2019. The ultra-mini percutaneous nephrolithotomy was carried out with epiduroscopy routinely used in neurosurgery pr...
Source: Urolithiasis - November 10, 2020 Category: Urology & Nephrology Source Type: research

Is health-related quality of life of patients after single-use flexible ureteroscopy superior to extracorporeal shock wave lithotripsy? A randomised prospective study
AbstractThe aims of the study were to compare the change in the Wisconsin Stone Quality of Life (WISQOL) score in patients who underwent retrograde intrarenal surgery (RIRS) single-use ureteroscope or extracorporeal shock wave lithotripsy (ESWL) with a calculation of quality-adjusted life-years (QALYs). 158 patients treated with urinary stone disease were randomly divided into 80 patients in the validation and 78 patients in the intervention arm. Patients in the intervention arm were randomly divided into the RIRS or the ESWL group. Linguistic validation of the WISQOL into the Slovak language was performed using a  st...
Source: Urolithiasis - November 9, 2020 Category: Urology & Nephrology Source Type: research

Air vs contrast pyelogram for initial puncture access in percutaneous nephrolithotomy: a randomized controlled trial
Conclusion: Air pyelogram is a feasible, safe, cost effective and efficient access alternative to contrast pyelogram and in difficult situation a mixture of both is better th an using one. (Source: Urolithiasis)
Source: Urolithiasis - November 7, 2020 Category: Urology & Nephrology Source Type: research

Kidney stone formation and the gut microbiome are altered by antibiotics in genetic hypercalciuric stone-forming rats
AbstractAntibiotics can alter the gut microbiome (GMB), which may be associated with stone disease. We sought to determine the effect that antibiotics have on the GMB, urine ion excretion and stone formation in genetic hypercalciuric stone-forming (GHS) rats. 116th generation GHS rats were fed a fixed amount of a normal calcium (1.2%) and phosphate (0.65%) diet, and divided into three groups (n = 10): control (CTL) diet, or supplemented with ciprofloxacin (Cipro, 5 mg/day) or Bactrim (250 mg/day). Urine and fecal pellets were collected over 6, 12 and 18 weeks. Fecal DNA was amplified across the...
Source: Urolithiasis - November 7, 2020 Category: Urology & Nephrology Source Type: research

A different perspective on the filtration barrier after kidney stone formation: An immunohistochemical and biochemical study
AbstractThe aim of this study is to investigate whether the filtration barrier is affected by experimental kidney stone formation. Thirty-two rats divided into 4 equally groups (n = 8) at random. Group I control; Group II 1% ethylene glycol; Group III 1% Ethylene glycol + 0.25% Ammonium chloride; Group IV 1% Ethylene glycol + 0.5% Ammonium chloride group. Tissues applied hematoxylin–eosin, periodic-acid-Schiff, Pizzolato's staining. Immunohistochemically staine d with integrin α3β1, type IV collagen, laminin, nephrin, CD2-associated protein (CD2AP) and podocin to s...
Source: Urolithiasis - November 5, 2020 Category: Urology & Nephrology Source Type: research

Re: Gul A, Gul M. Intracutaneous sterile water injection for pain relief during extracorporeal shock wave lithotripsy: comparison with diclofenac sodium. Urolithiasis. 2020 Apr;48(2):103 –108. doi:10.1007/s00240-019-01147-9. Epub 2019 Jul 5
(Source: Urolithiasis)
Source: Urolithiasis - October 29, 2020 Category: Urology & Nephrology Source Type: research

ENIUS. European Network of multidisciplinary research to Improve the Urinary Stents. COSTS Actions. CA16217. European Cooperation in Science & amp; Technology
(Source: Urolithiasis)
Source: Urolithiasis - October 28, 2020 Category: Urology & Nephrology Source Type: research

Usability of shear wave elastography to predict the success of extracorporeal shock-wave lithotripsy: prospective pilot study
AbstractThe present study is intended to investigate the usability of shear wave elastography (SWE) in predicting the success of extracorporeal shock-wave lithotripsy (ESWL) used in kidney stone treatment. ESWL was performed on a total number of 52 patients diagnosed with kidney stones between May 2019 and July 2020. The presence of a residual stone greater than 4  mm was accepted as failure. The patients were divided into two groups as ESWL success and ESWL failure. SWE and Hounsfield unit (HU) measurements of stones were performed in all patients before ESWL. The two groups were compared in terms of age, gender, sto...
Source: Urolithiasis - October 26, 2020 Category: Urology & Nephrology Source Type: research

The effect of shock wave lithotripsy and retrograde intrarenal surgery on health-related quality of life in 10 –20 mm renal stones: a prospective randomized pilot study
AbstractThe effects of treatment modalities such as retrograde intrarenal surgery (RIRS) and shock wave lithotripsy (SWL) on health-related quality of life (HRQoL) were determined in patients with renal stones between 10 and 20  mm. A total of 120 patients were included in the study and prospectively randomized to RIRS or SWL group. A total of 39 patients experienced treatment failure and finally 81 patients (45 patients in the RIRS group, 36 patients in the SWL group) were analyzed for HRQoL. SF-36 survey was used to det ermine HRQoL pre-operatively, post-operative day 1 and 1 month. The patient and stone charac...
Source: Urolithiasis - October 19, 2020 Category: Urology & Nephrology Source Type: research

Urine and stone analysis for the investigation of the renal stone former: a consensus conference
AbstractThe Consensus Group deliberated on a number of questions concerning urine and stone analysis over a period of months, and then met to develop consensus. The Group concluded that analyses of urine and stones should be routine in the diagnosis and treatment of urinary stone diseases. At present, the 24-h urine is the most useful type of urine collection, and accepted methods for analysis are described. Patient education is also important for obtaining a proper urine sample. Graphical methods for reporting urine analysis results can be helpful both for the physician and for educating the patient as to proper dietary c...
Source: Urolithiasis - October 13, 2020 Category: Urology & Nephrology Source Type: research

Multimodal imaging reveals a unique autofluorescence signature of Randall ’s plaque
AbstractKidney stones frequently develop as an overgrowth on Randall ’s plaque (RP) which is formed in the papillary interstitium. The organic composition of RP is distinct from stone matrix in that RP contains fibrillar collagen; RP in tissue has also been shown to have two proteins that are also found in stones, but otherwise the molecular constituents of RP are unstudied. We hypothesized that RP contains unique organic molecules that can be differentiated from the stone overgrowth by fluorescence. To test this, we used micro-CT-guided polishing to expose the interior of kidney stones for multimodal imaging with mu...
Source: Urolithiasis - October 6, 2020 Category: Urology & Nephrology Source Type: research

In-vitro and in-vivo new evidence for Flexor ® Vue™ deflecting endoscopic system use: optimization of the stone free rate (SFR) after flexible ureteroscopy and Ho:YAG laser lithotripsy
We reported no relevant complications (Clavien–Dindo >  2); one patient had fever and was treated with antibiotics. The experimental in-vitro model demonstrated the efficacy of FVDES, allowing the removal of about 90% of fragments.Our study showed that FVDES is effective when used as a tool for retrieval of residual fragments at the end of f-URS. This technology could ensure a complete cleaning of the intrarenal collecting system and represent a safe alternative to basketing. (Source: Urolithiasis)
Source: Urolithiasis - September 30, 2020 Category: Urology & Nephrology Source Type: research

CT-related parameters and Framingham score as predictors of spontaneous passage of ureteral stones  ≤ 10 mm: results from a prospective, observational, multicenter study
AbstractTo investigate the reliability of newly defined CT-related parameters and cardiovascular risk factors in groups adjusted for stone size and location to predict spontaneous stone passage (SP) of uncomplicated ureteral stones  ≤ 10 mm. The data of 280 adult patients with solitary unilateral ureteral stones ≤ 10 mm in diameter in non-contrast computed tomography were prospectively recorded. All patients undergoing a four-week observation protocol with medical expulsive therapy using tamsulosin were divided i nto two groups according to SP or no SP. Demographic, clinical and ...
Source: Urolithiasis - September 26, 2020 Category: Urology & Nephrology Source Type: research

The utility of automated volume analysis of renal stones before and after shockwave lithotripsy treatment
This study aimed to evaluate the additional utility of an automated method of estimating volume for stones being treated with shockwave lithotripsy (SWL) using computed tomography (CT) images compared to manual measurement. Utility was assessed as the ability to accurately measure stone burden before and  after SWL treatment, and whether stone volume is a better predictor of SWL outcome than stone diameter. 72 patients treated with SWL for a renal stone with available CT scans before and after treatment were included. Stone axes measurement and volume estimation using ellipsoid equations were comp ared to volume ...
Source: Urolithiasis - September 13, 2020 Category: Urology & Nephrology Source Type: research

Surface analysis of ureteral stent before and after implantation in the bodies of child patients
AbstractThe aim of this work was to determine which part of a double-J ureteral stent (DJ stents) showed the highest tendency to crystal, calculi, and biofilm deposition after ureterorenoscopic-lithotripsy procedure (URS-L) to treat calcium oxalate stones. Additionally, the mechanical strength and the stiffness of DJ stents were evaluated before and after exposure to urine. Obtained results indicated that the proximal (renal pelvis) and distal (urinary bladder) part is the most susceptible for post-URS-L fragments and urea salt deposition. Both, the outer and inner surfaces of the DJ ureteral stents were completely covered...
Source: Urolithiasis - September 8, 2020 Category: Urology & Nephrology Source Type: research

Trends in the prevalence of kidney stones in the United States from 2007 to 2016
In conclusion, there was substantial variability in KS prevalence across individual 2-year time periods. This variation of period-specific prevalence values emphasizes the im portance of looking at long-term trends and using more than a single 2-year cycle in analyses to increase the precision of the estimate. However, there was an overall increase in the prevalence of KS over 2007-2016. (Source: Urolithiasis)
Source: Urolithiasis - August 31, 2020 Category: Urology & Nephrology Source Type: research

In Memoriam: Jose Manuel Reis dos Santos
(Source: Urolithiasis)
Source: Urolithiasis - August 28, 2020 Category: Urology & Nephrology Source Type: research

The feasibility of multiple-tract mini-percutaneous nephrolithotomy as an overnight surgery for the treatment of complex kidney stones
AbstractTo demonstrate the feasibility of applying multiple-tract percutaneous nephrolithotomy (PCNL) as an overnight surgery for treatment of complex kidney stones. We reviewed a prospectively collected database of all multiple-tract PCNL planned as overnight surgery performed by a single surgeon since 2018. A clinical pathway including the removal of nephrostomy tube and discharge on the morning after surgery was carried out. A definition for tube removal was outlined. Ability to adhere to the pathway and achieving the described parameters and whether any resulting complications occurred were determined. A total of 136 c...
Source: Urolithiasis - August 23, 2020 Category: Urology & Nephrology Source Type: research

A comparative study of endoscopic combined intrarenal surgery (ECIRS) in the galdakao-modified supine valdivia (GMSV) position and minimally invasive percutaneous nephrolithotomy for complex nephrolithiasis: a retrospective single-center study
AbstractThe aim of this research is to compare the efficiency and safety between endoscopic combined intrarenal surgery (ECIRS) in the Galdakao-modified Supine Valdivia (GMSV) position and minimally invasive percutaneous nephrolithotomy (Mini-PCNL) in a single session for the treatment of complex nephrolithiasis. 140 consecutive patients who were diagnosed with multiple pyelocaliceal stones or staghorn renal calculi were enrolled and reviewed retrospectively. Demographic, clinical information and surgical outcomes were collected and analyzed. Demographic variables and stone characteristics did not show statistically differ...
Source: Urolithiasis - August 9, 2020 Category: Urology & Nephrology Source Type: research

Decreased hemoglobin as a quantifiable indicator of renal arterial embolization in post-percutaneous nephrolithotomy hemorrhage
AbstractTo determine quantifiable indicators for post-percutaneous nephrolithotomy (PCNL) renal arterial embolization. A total of 2043 patients who underwent PCNL from September 2012 to March 2018 were reviewed retrospectively. Post-operative hemorrhage patients were extracted and divided into two groups according to treatment methods (conservative methods or super-selective renal arterial embolization [SRAE]). Demographic characteristics and hemorrhage outcomes were compared between the two groups by univariable analysis. Multivariable logistic regression was used to reveal the association between hemorrhage outcome facto...
Source: Urolithiasis - August 7, 2020 Category: Urology & Nephrology Source Type: research

Oral chemolysis is an effective, non-invasive therapy for urinary stones suspected of uric acid content
AbstractDespite the possible benefit from avoiding stone surgery with all its possible complications, oral chemolysis is rarely performed in patients with urinary stones suspected of uric acid content. Among the reasons for its limited use is the sparse and low-quality data on its efficacy and the lack of reliable factors predicting its outcome. We thus performed a retrospective single-center cohort study of 216 patients (median patient age 63  years) with 272 renal (48%) and/or ureteral (52%) stones treated with oral chemolysis from 01/2010 to 12/2019. Patients with low urine pH (
Source: Urolithiasis - August 6, 2020 Category: Urology & Nephrology Source Type: research

SIRS following percutaneous nephrolithotomy is unpreventable by intensive therapeutic antibiotics in patients with positive urine culture: too soon to conclude
(Source: Urolithiasis)
Source: Urolithiasis - August 4, 2020 Category: Urology & Nephrology Source Type: research

Preoperative risk factors for complications of percutaneous nephrolithotomy
This study was conducted to evaluate preoperative risk factors for development of complications of percutaneous nephrolithotomy (PCNL). All consecutive patients aged  ≥ 16 years who underwent PCNL during 2015 were retrospectively reviewed. Non-contrast CT (NCCT) was performed for all patients to evaluate stone complexity. The technique of PCNL was the same for all patients. Intra-operative and postoperative complications were recorded and classified based on modified Clavien system. The differences in preoperative data (patients, renal and stone characteristics including Guy’s and STONE scores) ...
Source: Urolithiasis - July 31, 2020 Category: Urology & Nephrology Source Type: research

Calcium oxalate crystal deposition in the kidney: identification, causes and consequences
AbstractCalcium oxalate (CaOx) crystal deposition within the tubules is often a perplexing finding on renal biopsy of both native and transplanted kidneys. Understanding the underlying causes may help diagnosis and future management. The most frequent cause of CaOx crystal deposition within the kidney is hyperoxaluria. When this is seen in native kidney biopsy, primary hyperoxaluria must be considered and investigated further with biochemical and genetic tests. Secondary hyperoxaluria, for example due to enteric hyperoxaluria following bariatric surgery, ingested ethylene glycol or vitamin C overdose may also cause CaOx de...
Source: Urolithiasis - July 26, 2020 Category: Urology & Nephrology Source Type: research

Characteristics of the genotype and phenotype in Chinese primary hyperoxaluria type 1 populations
Conclusions: heterogeneity between genotype and phenotype was observed and described in Chinese PH1 patients. c.815_816insGA and c.33_34insC which were recognized asAGXT mutation hotspot regions in China implied a poor prognosis. And c.1049G>A was not determined as the race-specific mutation of Pakistani. (Source: Urolithiasis)
Source: Urolithiasis - June 17, 2020 Category: Urology & Nephrology Source Type: research

A single center ’s experience in pediatric cystine stone disease management: what changed over time?
AbstractThe authors aimed to evaluate the factors affecting clinical outcomes of cystine stone disease in children and to understand the change in disease management over time. Between January 1991 and September 2017, the demographic and clinical data of pediatric patients with documented cystine stone disease were retrospectively analyzed. Patients with at least 12-month follow-up were included. Disease management and clinical outcomes were compared between the first and second 35 patients managed during the study ’s time frame. A total of 70 patients were included. The female to male ratio was 30/40. The mean age a...
Source: Urolithiasis - June 16, 2020 Category: Urology & Nephrology Source Type: research

Simple dietary advice targeting five urinary parameters reduces urinary supersaturation in idiopathic calcium oxalate stone formers
AbstractAmong 208 kidney stone patients referred within 2  years, 75 patients (66 men, nine women) with truly idiopathic calcium oxalate stones (ICSF) were recruited. Dietary advice (DA) aimed at (1) urine dilution, (2) reduced crystallization promotion (lowering oxalate), and (3) increased crystallization inhibition (increasing citrate). We recommended h igher intakes of fluid and calcium with meals/snacks (reducing intestinal oxalate absorption) as well as increased alkali and reduced meat protein (acid) for increasing urinary citrate. The intended effects of DA were elevations in urine volume, calcium (U-Ca) and ci...
Source: Urolithiasis - June 9, 2020 Category: Urology & Nephrology Source Type: research

Plasma oxalate: comparison of methodologies
AbstractMeasurement of oxalate in the blood is essential for monitoring primary hyperoxaluria patients with progressive renal impairment and on dialysis prior to transplantation. As no external quality assurance scheme is available for this analyte, we conducted a sample exchange scheme between six laboratories specifically involved with the investigation of primary hyperoxaluria to compare results. The methodologies compared were gas chromatography/mass spectrometry (GCMS), ion chromatography with mass spectrometry (ICMS), and enzymatic methods using oxalate oxidase and spectrophotometry. Although individual laboratories ...
Source: Urolithiasis - May 28, 2020 Category: Urology & Nephrology Source Type: research

How urinary stone emergencies changed in the time of COVID-19?
(Source: Urolithiasis)
Source: Urolithiasis - May 27, 2020 Category: Urology & Nephrology Source Type: research

Editorial comment
(Source: Urolithiasis)
Source: Urolithiasis - May 25, 2020 Category: Urology & Nephrology Source Type: research

Derivation of a clinical predicting rule for obstructive urolithiasis and alternative diagnosis requiring urgent intervention: the CLAD score
AbstractMost patients with renal colic are discharged from the emergency department (ED) after evaluation and pain alleviation. These patients may not require urgent imaging by computed tomography. We derived a clinical prediction score in patients with renal colic to identify those at very low risk for complications and alternative diagnoses requiring urgent intervention. This retrospective chart review was carried out in 2 ED at an urban university hospital from January to December 2015. All patients with a diagnosis of renal colic were included. The primary outcome was an intervention required for renal colic or alterna...
Source: Urolithiasis - May 19, 2020 Category: Urology & Nephrology Source Type: research

How does the COVID-19 pandemic affect the preoperative evaluation and anesthesia applied for urinary stones? EULIS eCORE –IAU multicenter collaborative cohort study
In this study it is aimed to identify the up-to-date practice patterns related to preoperative evaluation and anesthesia for stone disease interventions during COVID-19 pandemic. The data of 473 patients from 11 centers in 5 different countries underwent interventions for urinary stones during the Covid-19 pandemic was collected and analyzed retrospectively. Information on the type of the stone related conditions, management strategies, anesthesiologic evaluation, anesthesia methods, and any alterations related to COVID-19 pandemic was collected. During the preoperative anesthesia evaluation thorax CT was performed in 268 ...
Source: Urolithiasis - May 19, 2020 Category: Urology & Nephrology Source Type: research

The surgeon ’s role on chemical investigations of the composition of urinary stones
AbstractThe chemical analysis of an urolith is often interpreted as “stone’s composition”. However, it must be taken into consideration, that in most cases, only a fragment of the stone has been sent to the laboratory. In some recurrent patients, stone compositions either vary considerably between episodes or the analytical result obtained from the stone fragm ent does not fit with the data of e.g. current 24 h-urinalysis or urinary pH-records. The question arises, whether this outcome may be the result of an improper stone sampling scheme. On a simple layered 2D-stone model composed of two mine...
Source: Urolithiasis - May 19, 2020 Category: Urology & Nephrology Source Type: research

Are conventional stone analysis techniques reliable for the identification of 2,8-dihydroxyadenine kidney stones? A case series
The objective of this study was to examine the accuracy of stone analysis for identification of DHA. Medical records of patients referred to the APRT Deficiency Research Program of the Rare Kidney Stone Consortium in 2010 –2018 with a diagnosis of APRT deficiency based on kidney stone analysis were reviewed. The diagnosis was verified by measurement of APRT enzyme activity or genetic testing. Attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectra of pure crystalline DHA and a kidney stone obtaine d from one of the confirmed APRT deficiency cases were generated. The ATR-FTIR spectrum of the kidney s...
Source: Urolithiasis - May 11, 2020 Category: Urology & Nephrology Source Type: research

Gender-related differences in the performance of sequential organ failure assessment (SOFA) to predict septic shock after percutaneous nephrolithotomy
AbstractThe study aims to identify whether gender differences exist in the sequential organ failure assessment (SOFA) score to the extent of affecting its predictive accuracy for septic shock after percutaneous nephrolithotomy (PCNL). A retrospective study of 612 patients undergoing PCNL was performed. The SOFA scores of male and female groups were compared to identify any gender differences. The ROC curve was used to find differences between the original and adjusted SOFA scores. Postoperative septic shock developed in 21 (3.43%) cases. A marginally significant discrepancy in median SOFA scores between genders was discove...
Source: Urolithiasis - May 4, 2020 Category: Urology & Nephrology Source Type: research

Quality of life in patients with kidney stones: translation and validation of the Spanish Wisconsin Stone Quality of Life Questionnaire
AbstractThe Spanish version of the Wisconsin Stone Quality of Life (WISQOL) questionnaire was developed and validated. A double-back translation of the WISQOL was conducted and syntactic amendments were made, resulting in the Spanish version of the WISQOL (S-WISQOL) which then went through a readability analysis. Stone formers from two hospitals in Mexico (Merida and Monterrey) filled in the S-WISQOL and the Short Form 36 (SF36). Convergent validity was assessed by the correlation of both questionnaires. Internal consistency was evaluated by Cronbach ’sα, and external validity by comparing between centers. The ...
Source: Urolithiasis - May 4, 2020 Category: Urology & Nephrology Source Type: research

Correction to: Nutrients, vitamins, probiotics and herbal products: an update of their role in urolithogenesis
The original version of this article unfortunately contained a mistake. (Source: Urolithiasis)
Source: Urolithiasis - April 27, 2020 Category: Urology & Nephrology Source Type: research