Synergistic antibacterial effect and mechanism between Cu < sub > 2 < /sub > O nanoparticles and quaternary ammonium salt in moisture-curable acrylic coatings
Colloids Surf B Biointerfaces. 2024 Apr 12;238:113914. doi: 10.1016/j.colsurfb.2024.113914. Online ahead of print.ABSTRACTCombining with various antibacterial mechanisms is the preferred strategy to fabricate coatings with effective antibacterial performance. Herein, Cu2O nanoparticles and dimethyloctadecyl [3-(trimethoxysilyl) propyl] ammonium chloride, a kind of quaternary ammonium salt (QAS), were simultaneously incorporated into a moisture-curable acrylic resin in order to achieve both contact-killing and release-killing abilities for antibacterial coatings. The surface morphology, surface composition and basic propert...
Source: Colloids and Surfaces - April 25, 2024 Category: Biotechnology Authors: Haofeng Xiao Shuxue Zhou Source Type: research
Exploring the antifungal potential of Annona muricata leaf extract-loaded hydrogel in treating vulvovaginal candidiasis
This study presents an innovative hydrogel formulation containing the ethanolic extract from A. muricata leaves designed to control C. albicans in an in vivo model of vulvovaginal candidiasis. Here, we report the development, thermal, physicochemical and rheological characterization of a Carbopol®-based hydrogel containing A. muricata extract. Furthermore, we evaluated its activity in a vulvovaginal candidiasis in vivo model. Thermal analyses indicated that the addition of the extract increased the polymer-polymer and polymer-solvent interactions.Rheological analysis showed a decrease in the viscosity and elasticity of th...
Source: Colloids and Surfaces - April 25, 2024 Category: Biotechnology Authors: Lara Melo Campos Ari S érgio de Oliveira Lemos Priscila de Lima Paula Vin ícius Novaes da Rocha Marcelo Gonzaga de Freitas Ara újo Guilherme Diniz Tavares Thais Nogueira Barradas Wesley William Gon çalves Nascimento Angelo M ácio Leite Denadai Luiz F Source Type: research
Hierarchical antibiotic delivery system based on calcium phosphate cement/montmorillonite-gentamicin sulfate with drug release pathways
Colloids Surf B Biointerfaces. 2024 Apr 21;238:113925. doi: 10.1016/j.colsurfb.2024.113925. Online ahead of print.ABSTRACTAntibiotic-loaded calcium phosphate cement (CPC) has emerged as a promising biomaterial for drug delivery in orthopedics. However, there are problems such as the burst release of antibiotics, low cumulative release ratio, inappropriate release cycle, inferior mechanical strength, and poor anti-collapse properties. In this research, montmorillonite-gentamicin (MMT-GS) was fabricated by solution intercalation method and served as the drug release pathways in CPC to avoid burst release of GS, achieving pro...
Source: Colloids and Surfaces - April 24, 2024 Category: Biotechnology Authors: Lei Chen Xiuying Lin Min Wei Bo Zhang Yani Sun Xi Chen Shitong Zhang Hao Zhang Jieyu Zhang Xiaojiao Yu Binghua Yao Kang Zhao Yufei Tang Quanchang Tan Zixiang Wu Source Type: research
Hyaluronic acid functionalized iron-platinum nanoparticles for photothermal therapy and photoacoustic imaging
This study represents an innovative approach to construct multi-functional nanoplatforms for cancer diagnosis and therapy by combining hyaluronic acid (HA) with iron-platinum nanoparticles (FePt NPs). These HA-coated FePt NPs, referred to as FePt@HA NPs, demonstrated remarkable biocompatibility, high absorption, and excellent light-to-heat conversion properties in the near-infrared (NIR) region, making them ideal candidates for photothermal therapy (PTT). In vitro studies revealed their effective cancer cell eradication under NIR laser irradiation, while in vivo experiments on mice showcased their superior heating capabili...
Source: Colloids and Surfaces - April 19, 2024 Category: Biotechnology Authors: Thi Tuong Vy Phan Sudip Mondal Madhappan Santhamoorthy Thi Thuy Truong Thanh Phuoc Nguyen Junghwan Oh Source Type: research
Hyaluronic acid functionalized iron-platinum nanoparticles for photothermal therapy and photoacoustic imaging
This study represents an innovative approach to construct multi-functional nanoplatforms for cancer diagnosis and therapy by combining hyaluronic acid (HA) with iron-platinum nanoparticles (FePt NPs). These HA-coated FePt NPs, referred to as FePt@HA NPs, demonstrated remarkable biocompatibility, high absorption, and excellent light-to-heat conversion properties in the near-infrared (NIR) region, making them ideal candidates for photothermal therapy (PTT). In vitro studies revealed their effective cancer cell eradication under NIR laser irradiation, while in vivo experiments on mice showcased their superior heating capabili...
Source: Colloids and Surfaces - April 19, 2024 Category: Biotechnology Authors: Thi Tuong Vy Phan Sudip Mondal Madhappan Santhamoorthy Thi Thuy Truong Thanh Phuoc Nguyen Junghwan Oh Source Type: research
Recent developments in ureteral stent: Substrate material, coating polymer and technology, therapeutic function
Colloids Surf B Biointerfaces. 2024 Apr 12;238:113916. doi: 10.1016/j.colsurfb.2024.113916. Online ahead of print.ABSTRACTThe ureteral stent is an effective treatment for clinical ureteral stricture following urological surgery, and the functional coating of the stent could effectively inhibit bacterial colonization and other complications. The present review provides an analysis and description of the materials used in ureteral stents and their coatings. Emphasis is placed on the technological advancements of functional coatings, taking into consideration the characteristics of these materials and the properties of their ...
Source: Colloids and Surfaces - April 18, 2024 Category: Biotechnology Authors: Kai-Chao Wen Zheng-An Li Ji-Heng Liu Chuan Zhang Feng Zhang Feng-Qian Li Source Type: research
Recent developments in ureteral stent: Substrate material, coating polymer and technology, therapeutic function
Colloids Surf B Biointerfaces. 2024 Apr 12;238:113916. doi: 10.1016/j.colsurfb.2024.113916. Online ahead of print.ABSTRACTThe ureteral stent is an effective treatment for clinical ureteral stricture following urological surgery, and the functional coating of the stent could effectively inhibit bacterial colonization and other complications. The present review provides an analysis and description of the materials used in ureteral stents and their coatings. Emphasis is placed on the technological advancements of functional coatings, taking into consideration the characteristics of these materials and the properties of their ...
Source: Colloids and Surfaces - April 18, 2024 Category: Biotechnology Authors: Kai-Chao Wen Zheng-An Li Ji-Heng Liu Chuan Zhang Feng Zhang Feng-Qian Li Source Type: research
Tumor microenvironment-responsive size-changeable and biodegradable HA-CuS/MnO < sub > 2 < /sub > nanosheets for MR imaging and synergistic chemodynamic therapy/phototherapy
Colloids Surf B Biointerfaces. 2024 Apr 16;238:113921. doi: 10.1016/j.colsurfb.2024.113921. Online ahead of print.ABSTRACTTumor microenvironment (TME)-responsive size-changeable and biodegradable nanoplatforms for multimodal therapy possess huge advantages in anti-tumor therapy. Hence, we developed a hyaluronic acid (HA) modified CuS/MnO2 nanosheets (HCMNs) as a multifunctional nanoplatform for synergistic chemodynamic therapy (CDT)/photothermal therapy (PTT)/photodynamic therapy (PDT). The prepared HCMNs exhibited significant NIR light absorption and photothermal conversion efficiency because of the densely deposited ultr...
Source: Colloids and Surfaces - April 17, 2024 Category: Biotechnology Authors: Zhen Jin Yunkai Wang Miaomiao Han Li Wang Fei Lin Qianfang Jia Wu Ren Jiawei Xu Wenhao Yang Guo-An Zhao Xuming Sun Changqin Jing Source Type: research
Sulfated glyco-based hydrogels as self-healing, adhesive, and anti-inflammatory dressings for wound healing
Colloids Surf B Biointerfaces. 2024 Apr 12;238:113915. doi: 10.1016/j.colsurfb.2024.113915. Online ahead of print.ABSTRACTHydrogels have emerged as a new type of wound dressing materials that involved in different stages of the healing processes. However, most of the existing wound dressings mainly offer a protective and moisturizing layer to prevent cross-infection, while the anti-inflammatory and anti-oxidative properties are frequently induced by extra addition of other bioactive molecules. Here, a novel type of sulfated glyco-functionalized hydrogels for wound dressing was prepared through the hybrid supramolecular co-...
Source: Colloids and Surfaces - April 17, 2024 Category: Biotechnology Authors: Baotong Ye Guodong Lu Jingjing Zhou Yi Li Yongxin Ma Yan Zhang Jinghua Chen Source Type: research
Biomembrane camouflaged nanoparticles: A paradigm shifts in targeted drug delivery system
Colloids Surf B Biointerfaces. 2024 Apr 4;238:113893. doi: 10.1016/j.colsurfb.2024.113893. Online ahead of print.ABSTRACTTargeted drug delivery has emerged as a pivotal approach within precision medicine, aiming to optimize therapeutic efficacy while minimizing systemic side effects. Advanced biomimetic membrane-coated formulations have garnered significant interest from researchers as a promising strategy for targeted drug delivery, site-specific accumulation and heightened therapeutic outcomes. Biomimetic nanotechnology is able to retain the biological properties of the parent cell thus are able to exhibit superior targe...
Source: Colloids and Surfaces - April 17, 2024 Category: Biotechnology Authors: Saba Asif Qureshi Km Rafiya Sakshi Awasthi Abhishek Jain Arif Nadaf Nazeer Hasan Prashant Kesharwani Farhan Jalees Ahmad Source Type: research
Dendritic polymer prodrug-based unimolecular micelles for pH-responsive co-delivery of doxorubicin and camptothecin with synergistic controlled drug release effect
Colloids Surf B Biointerfaces. 2024 Apr 11;238:113906. doi: 10.1016/j.colsurfb.2024.113906. Online ahead of print.ABSTRACTCombination chemotherapy has been recognized as a more powerful strategy for tumor treatment rather than the single chemotherapy. However, the interactive mechanism of the two hydrophobic chemotherapeutic drugs has not been explored by now. Aiming for a better synergistic effect, such interactive mechanism was investigated in the present work, by designing CPT@DOX-DPUTEA-PEG nanomedicine with encapsulated camptothecin (CPT) and conjugated doxorubicin (DOX). The synergistic controlled drug release effect...
Source: Colloids and Surfaces - April 14, 2024 Category: Biotechnology Authors: Wei Chen Peng Liu Source Type: research
Applications and advancements of polysaccharide-based nanostructures for enhanced drug delivery
Colloids Surf B Biointerfaces. 2024 Mar 30;238:113883. doi: 10.1016/j.colsurfb.2024.113883. Online ahead of print.ABSTRACTGrowing demand for highly effective, site-specific delivery of pharmaceuticals and nutraceuticals using nano-sized carriers has prompted increased scrutiny of carrier biocompatibility and biodegradability. To address these concerns, biodegradable natural polymers have emerged as a transformative domain, offering non-toxic, precisely targetable carriers capable of finely modulating cargo pharmacokinetics while generating innocuous decomposition by-products. This comprehensive review illuminates the emerg...
Source: Colloids and Surfaces - April 14, 2024 Category: Biotechnology Authors: Asra Fatimah Kareemi Sweta Likhitkar Source Type: research
Development of a precision tumor bone metastasis model by a magnetic micro-living-motor system
Colloids Surf B Biointerfaces. 2024 Mar 27;238:113877. doi: 10.1016/j.colsurfb.2024.113877. Online ahead of print.ABSTRACTAn ideal bone metastasis animal model is critical and fundamental for mechanistic research and following development of new drug and treatment. Caudal artery (CA) injection allows bone metastasis in the hindlimb, while in-depth targeted and quantitative studies of bone metastasis require a new model to overcome its limitations. Here, we developed a targeted, quantitative, and highly consistent method for the modeling of bone metastasis with cell-based magnetic micro-living-motor (MLM) system created by ...
Source: Colloids and Surfaces - April 14, 2024 Category: Biotechnology Authors: Jialu Zhang Zhengyuan Wang Dingyi Zhang Qiyan Chen Jiawei Xu Luxia Tang Jinyan Luo Qiusui Mai Xia Lu Leyi Tan Ning Gan Qianli Jiang Source Type: research
Insight into the structural characteristics of self-assembled liposome with epigallocatechin gallate/alcohol dehydrogenase
In this study, the encapsulation and structural characteristics of the self-assembled liposome formed by epigallocatechin gallate (EGCG) and alcohol dehydrogenase (ADH) were studied. According to the results, EGCG significantly increased the catalytic activity of ADH with a 33.33 % activation rate and the liposomes were able to entrap EGCG-ADH with an effectiveness of 88.94 %. The self-assembled monolayers had nanometer-sized particles, and the excellent self-assembled system was demonstrated by the low PDI value and high surface absolute potential. The scanning electron microscope showed that the self-assembled liposome w...
Source: Colloids and Surfaces - April 14, 2024 Category: Biotechnology Authors: Xiaodan Zhang Lili Liu Xueyuan Jiao Kenan Su Weiwei Cheng Baocheng Xu Source Type: research
Coatless modification of 3D-printed Ti6Al4V implants through tailored Cu ion implantation combined with UV photofunctionalization to enhance cell attachment, osteogenesis and angiogenesis
In conclusion, UV/Ti-Cu is a novel attempt to apply two coatless techniques for the surface modification of 3DTi. In addition, it is considered a potential bone substrate for repairing bone defects.PMID:38615392 | DOI:10.1016/j.colsurfb.2024.113891 (Source: Colloids and Surfaces)
Source: Colloids and Surfaces - April 14, 2024 Category: Biotechnology Authors: Jiedong Wang Zehao Jing Chuan Yin Zhengguang Wang Shengxin Zeng Xiaolin Ma Yufeng Zheng Hong Cai Zhongjun Liu Source Type: research
