In vitro corrosion and cytocompatibility of Mg-Zn-Ca alloys coated with FHA
This study aims to improve the degradation behavior of Mg-Zn-Ca alloys by electrodepositing fluorohydroxyapatite (FHA). We investigated the microstructure and bond strength of the deposition, as well as degradation and cellular reactions. After 15-30 days of degradation in Hanks solution, FHA deposited alloys showed enhanced stability and less pH change. The strong interfacial bond between FHA and the Mg-Zn-Ca substrate was verified through scratch tests (Critical loads: 10.73 ± 0.014 N in Mg-Zn-0.5Ca alloys). Cellular studies demonstrated that FHA-coated alloys exhibited good cytocompatibility and promoted the growth of ...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Weiwei Lan Jun Li Zhenjun Lv Shuang Liu Ziwei Liang Di Huang Xiaochun Wei Weiyi Chen Source Type: research
Combating infections from drug-resistant bacteria: Unleashing synergistic broad-spectrum antibacterial power with high-entropy MXene/CDs
Colloids Surf B Biointerfaces. 2024 Mar 26;238:113874. doi: 10.1016/j.colsurfb.2024.113874. Online ahead of print.ABSTRACTThe growing resistance of bacteria to antibiotics has posed challenges in treating associated bacterial infections, while the development of multi-model antibacterial strategies could efficient sterilization to prevent drug resistance. High-entropy MXene has emerged as a promising candidate for antibacterial synergy with inherent photothermal and photodynamic properties. Herein, a high-entropy nanomaterial of MXene/CDs was synthesized to amplify oxidative stress under near-infrared laser irradiation. We...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Panyong Wang Qiannan You Yulu Liu Huimin Miao Wen-Fei Dong Li Li Source Type: research
Dual targetable drug delivery system based on cell membrane camouflaged liposome for enhanced tumor targeting and improved anti-tumor efficiency
Colloids Surf B Biointerfaces. 2024 Apr 3;238:113892. doi: 10.1016/j.colsurfb.2024.113892. Online ahead of print.ABSTRACTReceptor and ligand binding mediated targeted drug delivery systems (DDS) sometimes fail to target to tumor sites, and cancer cell membrane (CCM) coating can overcome the dilemma of immune clearance and nonspecific binding of DDS in vivo. In order to enhance the targeting ability and improve the anti-tumor effect, a dual targeting DDS was established based on U87MG CCM mediated homologous targeting and cyclic peptide RGD mediated active targeting. The DDS was prepared by coating RGD doped CCM onto doxoru...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Meitao Duan Dan Zhou Junfang Ke Yan Chen Wenfeng Wu Yue Li Jungang Ren Li Wang Zhiqiang Zhang Chen Wang Source Type: research
In-situ growth of CeO < sub > 2 < /sub > on biofilms: Innovative nanoparticles for photothermal therapy & amp; multi-pronged attack on Alzheimer's disease
This study pioneered the in situ growth of cerium oxide nanoparticles on macrophage membranes (Ce-RAW). Further, carbon quantum dots (CQD) were biomimetically modified by Ce-RAW, leading to the synthesis of a multifunctional nanocomposite (CQD-Ce-RAW). Within the framework of this research, CQD-Ce-RAW was strategically combined with photothermal therapy (PTT), aiming to achieve a more significant therapeutic effect. The macrophage membrane confers the system with anti-phagocytic and anti-inflammatory biological functions. More importantly, the ultra-small size of cerium oxide grown on the membrane acts as a reactive oxygen...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Mingyuan Chi Jichun Liu Lianxin Li Yuewen Zhang Meng Xie Source Type: research
In vitro corrosion and cytocompatibility of Mg-Zn-Ca alloys coated with FHA
This study aims to improve the degradation behavior of Mg-Zn-Ca alloys by electrodepositing fluorohydroxyapatite (FHA). We investigated the microstructure and bond strength of the deposition, as well as degradation and cellular reactions. After 15-30 days of degradation in Hanks solution, FHA deposited alloys showed enhanced stability and less pH change. The strong interfacial bond between FHA and the Mg-Zn-Ca substrate was verified through scratch tests (Critical loads: 10.73 ± 0.014 N in Mg-Zn-0.5Ca alloys). Cellular studies demonstrated that FHA-coated alloys exhibited good cytocompatibility and promoted the growth of ...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Weiwei Lan Jun Li Zhenjun Lv Shuang Liu Ziwei Liang Di Huang Xiaochun Wei Weiyi Chen Source Type: research
Combating infections from drug-resistant bacteria: Unleashing synergistic broad-spectrum antibacterial power with high-entropy MXene/CDs
Colloids Surf B Biointerfaces. 2024 Mar 26;238:113874. doi: 10.1016/j.colsurfb.2024.113874. Online ahead of print.ABSTRACTThe growing resistance of bacteria to antibiotics has posed challenges in treating associated bacterial infections, while the development of multi-model antibacterial strategies could efficient sterilization to prevent drug resistance. High-entropy MXene has emerged as a promising candidate for antibacterial synergy with inherent photothermal and photodynamic properties. Herein, a high-entropy nanomaterial of MXene/CDs was synthesized to amplify oxidative stress under near-infrared laser irradiation. We...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Panyong Wang Qiannan You Yulu Liu Huimin Miao Wen-Fei Dong Li Li Source Type: research
Dual targetable drug delivery system based on cell membrane camouflaged liposome for enhanced tumor targeting and improved anti-tumor efficiency
Colloids Surf B Biointerfaces. 2024 Apr 3;238:113892. doi: 10.1016/j.colsurfb.2024.113892. Online ahead of print.ABSTRACTReceptor and ligand binding mediated targeted drug delivery systems (DDS) sometimes fail to target to tumor sites, and cancer cell membrane (CCM) coating can overcome the dilemma of immune clearance and nonspecific binding of DDS in vivo. In order to enhance the targeting ability and improve the anti-tumor effect, a dual targeting DDS was established based on U87MG CCM mediated homologous targeting and cyclic peptide RGD mediated active targeting. The DDS was prepared by coating RGD doped CCM onto doxoru...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Meitao Duan Dan Zhou Junfang Ke Yan Chen Wenfeng Wu Yue Li Jungang Ren Li Wang Zhiqiang Zhang Chen Wang Source Type: research
In-situ growth of CeO < sub > 2 < /sub > on biofilms: Innovative nanoparticles for photothermal therapy & amp; multi-pronged attack on Alzheimer's disease
This study pioneered the in situ growth of cerium oxide nanoparticles on macrophage membranes (Ce-RAW). Further, carbon quantum dots (CQD) were biomimetically modified by Ce-RAW, leading to the synthesis of a multifunctional nanocomposite (CQD-Ce-RAW). Within the framework of this research, CQD-Ce-RAW was strategically combined with photothermal therapy (PTT), aiming to achieve a more significant therapeutic effect. The macrophage membrane confers the system with anti-phagocytic and anti-inflammatory biological functions. More importantly, the ultra-small size of cerium oxide grown on the membrane acts as a reactive oxygen...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Mingyuan Chi Jichun Liu Lianxin Li Yuewen Zhang Meng Xie Source Type: research
In vitro corrosion and cytocompatibility of Mg-Zn-Ca alloys coated with FHA
This study aims to improve the degradation behavior of Mg-Zn-Ca alloys by electrodepositing fluorohydroxyapatite (FHA). We investigated the microstructure and bond strength of the deposition, as well as degradation and cellular reactions. After 15-30 days of degradation in Hanks solution, FHA deposited alloys showed enhanced stability and less pH change. The strong interfacial bond between FHA and the Mg-Zn-Ca substrate was verified through scratch tests (Critical loads: 10.73 ± 0.014 N in Mg-Zn-0.5Ca alloys). Cellular studies demonstrated that FHA-coated alloys exhibited good cytocompatibility and promoted the growth of ...
Source: Colloids and Surfaces - April 6, 2024 Category: Biotechnology Authors: Weiwei Lan Jun Li Zhenjun Lv Shuang Liu Ziwei Liang Di Huang Xiaochun Wei Weiyi Chen Source Type: research
Formation mechanism of a novel core-shell with tetradecyl dimethyl benzyl ammonium-modified montmorillonite interlayer nanofibrous membrane and its antimicrobial properties
Colloids Surf B Biointerfaces. 2024 Mar 31;238:113889. doi: 10.1016/j.colsurfb.2024.113889. Online ahead of print.ABSTRACTA novel core-shell with a tetradecyl dimethyl benzyl ammonium chloride-modified montmorillonite (TDMBA/MMT) interlayer silk fibroin (SF)/poly(lactic acid) (PLLA) nanofibrous membrane was fabricated using a simple conventional electrospinning method. Scanning electron microscopy and pore size analyses revealed that this core-shell with TDMBA/MMT interlayer maintained its nanofibrous morphology and larger pore structure more successfully than SF/PLLA nanofibrous membranes after treatment with 75% ethanol ...
Source: Colloids and Surfaces - April 4, 2024 Category: Biotechnology Authors: Qi Gu Changfa Zhu Ruobing Cheng Junlong Zhou Jintao He Tanlong Liu Yuxin Yang Yuan Lian Kuihua Zhang Source Type: research
Light-triggered AND logic tetrapeptide dynamic covalent assembly
Colloids Surf B Biointerfaces. 2024 Apr 1;238:113885. doi: 10.1016/j.colsurfb.2024.113885. Online ahead of print.ABSTRACTWe demonstrate light-triggered dynamic covalent assembly of a linear short tetrapeptide containing two terminal cysteine residues in an AND logic manner. A photobase generator is introduced to accomplish light-mediated pH regulation to increase the reduction potential of thiols in the tetrapeptide, which activates its oxidative polymerization through disulfide bonds. Interestingly, it is elucidated that under light irradiation, mere co-existence of photobase generator and the oxidizing agent permits the ...
Source: Colloids and Surfaces - April 4, 2024 Category: Biotechnology Authors: Yuhua Tang Liang Gao Jinbo Fei Source Type: research
Formation mechanism of a novel core-shell with tetradecyl dimethyl benzyl ammonium-modified montmorillonite interlayer nanofibrous membrane and its antimicrobial properties
Colloids Surf B Biointerfaces. 2024 Mar 31;238:113889. doi: 10.1016/j.colsurfb.2024.113889. Online ahead of print.ABSTRACTA novel core-shell with a tetradecyl dimethyl benzyl ammonium chloride-modified montmorillonite (TDMBA/MMT) interlayer silk fibroin (SF)/poly(lactic acid) (PLLA) nanofibrous membrane was fabricated using a simple conventional electrospinning method. Scanning electron microscopy and pore size analyses revealed that this core-shell with TDMBA/MMT interlayer maintained its nanofibrous morphology and larger pore structure more successfully than SF/PLLA nanofibrous membranes after treatment with 75% ethanol ...
Source: Colloids and Surfaces - April 4, 2024 Category: Biotechnology Authors: Qi Gu Changfa Zhu Ruobing Cheng Junlong Zhou Jintao He Tanlong Liu Yuxin Yang Yuan Lian Kuihua Zhang Source Type: research
Light-triggered AND logic tetrapeptide dynamic covalent assembly
Colloids Surf B Biointerfaces. 2024 Apr 1;238:113885. doi: 10.1016/j.colsurfb.2024.113885. Online ahead of print.ABSTRACTWe demonstrate light-triggered dynamic covalent assembly of a linear short tetrapeptide containing two terminal cysteine residues in an AND logic manner. A photobase generator is introduced to accomplish light-mediated pH regulation to increase the reduction potential of thiols in the tetrapeptide, which activates its oxidative polymerization through disulfide bonds. Interestingly, it is elucidated that under light irradiation, mere co-existence of photobase generator and the oxidizing agent permits the ...
Source: Colloids and Surfaces - April 4, 2024 Category: Biotechnology Authors: Yuhua Tang Liang Gao Jinbo Fei Source Type: research
Mucoadhesive phenylboronic acid-grafted carboxymethyl cellulose hydrogels containing glutathione for treatment of corneal epithelial cells exposed to benzalkonium chloride
Colloids Surf B Biointerfaces. 2024 Mar 29;238:113884. doi: 10.1016/j.colsurfb.2024.113884. Online ahead of print.ABSTRACTBenzalkonium chloride (BAK) is the most commonly-used preservative in topical ophthalmic medications that may cause ocular surface inflammation associated with oxidative stress and dry eye syndrome. Glutathione (GSH) is an antioxidant in human tears and able to decrease the proinflammatory cytokine release from cells and reactive oxygen species (ROS) formation. Carboxymethyl cellulose (CMC), a hydrophilic polymer, is one of most commonly used artificial tears and can promote the corneal epithelial cell ...
Source: Colloids and Surfaces - April 2, 2024 Category: Biotechnology Authors: Yung-Hsin Cheng Hao-Pai Huang Hsin-Ho Chen Source Type: research
Hybrid nanostructures of nitrogen-doped carbon dots and aromatic amino acids: Synthesis, interactions at interfaces and optical properties
Colloids Surf B Biointerfaces. 2024 Mar 30;238:113878. doi: 10.1016/j.colsurfb.2024.113878. Online ahead of print.ABSTRACTNitrogen-doped carbon dots (NCD) were synthesized using a simple and fast hydrothermal route, employing citric acid and urea as precursors. The resulting NCDs were non-covalently functionalized (conjugated) with aromatic amino acids, namely phenylalanine (Phe) and tryptophan (Trp). Atomic force microscopy revealed that the NCDs exhibit a disk-like morphology with an average diameter of approximately 60 nm and an average height of about 0.5 nm. Following conjugation, the particle height increased to arou...
Source: Colloids and Surfaces - April 2, 2024 Category: Biotechnology Authors: Djordje Trpkov Du šan Sredojević Jelena Pajovi ć Dragana To šić Du šan K Božanić Vladimir Djokovi ć Source Type: research
