Cu-MSNs and ZnO nanoparticles incorporated poly(ethylene glycol) diacrylate/sodium alginate double network hydrogel for simultaneous enhancement of osteogenic differentiation
In this study, a double network (DN) hydrogel was synthesized using poly(ethylene glycol) diacrylate (PEGDA) and sodium alginate (SA), incorporating copper-doped mesoporous silica nanospheres (Cu-MSNs) and zinc oxide nanoparticles (ZnO NPs). The blending of PEGDA and SA (PS) facilitates the double network and improves the less porous microstructure of pure PEGDA hydrogel. Furthermore, the incorporation of ZnO NPs and Cu-MSNs into the hydrogel network (PS@ZnO/Cu-MSNs) improved the mechanical properties of the hydrogel (Compressive strength = ⁓153 kPa and Young's modulus = ⁓ 1.66 kPa) when compared to PS hydrogel alone (...
Source: Colloids and Surfaces - March 1, 2024 Category: Biotechnology Authors: Esensil Man Hia Se Rim Jang Bikendra Maharjan Jeesoo Park Chan Hee Park Source Type: research
Tumor microenvironment-activatable nanocatalysts with chemodynamic therapy and enhanced autophagy for specific treatment of oral squamous cell carcinoma
This study presents a targeted treatment strategy for OSCC tumors while sparing normal cells, offering a potential alternative in the realm of adjuvant therapy.PMID:38422665 | DOI:10.1016/j.colsurfb.2023.113713 (Source: Colloids and Surfaces)
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Hongtao Xu Chongyang Zheng Zhiyuan Zhang Xiaojuan Huang Source Type: research
Enhancing immune modulation and bone regeneration on titanium implants by alleviating the hypoxic microenvironment and releasing bioactive ions
Colloids Surf B Biointerfaces. 2024 Feb 17;236:113805. doi: 10.1016/j.colsurfb.2024.113805. Online ahead of print.ABSTRACTBone implantation inevitably causes damage to surrounding vasculature, resulting in a hypoxic microenvironment that hinders bone regeneration. Although titanium (Ti)-based devices are widely used as bone implants, their inherent bioinert surface leads to poor osteointegration. Herein, a strontium peroxide (SrO2)-decorated Ti implant, Ti_P@SrO2, was constructed through coating with poly-L-lactic acid (PLLA) to alleviate the hypoxic microenvironment and transform the bioinert surface of the implant into a...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Dongdong Zhang Han Liu Xiaodong Xue Feihong Liu Jun Wu Feng Peng Donghui Wang Haobo Pan Mei Li Source Type: research
Development of pH-freshness smart label based on gellan gum film incorporated with red cabbage anthocyanins extract and its application in postharvest mushroom
Colloids Surf B Biointerfaces. 2024 Feb 28;236:113830. doi: 10.1016/j.colsurfb.2024.113830. Online ahead of print.ABSTRACTNovel colorimetric films based on gellan gum (GG) containing red cabbage anthocyanins extract (RCAE) were prepared as pH-freshness smart labels for real-time visual detection of mushroom freshness. The GG/RCAE films had excellent pH and ammonia sensitivity. The GG/RCAE-0.2-0.3 films had the highest sensitivity to acetic acid. The SEM micrographs, AFM images, FT-IR and XRD spectra demonstrated that RCAE were successfully combined into the film-forming substrate. The incorporation of RCAE resulted in the ...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Shouqing Zhan Fangxuan Yi Fanyun Hou Lisha Song Xiuxiu Chen Hai Jiang Xiangbo Han Xia Sun Zhanli Liu Source Type: research
Ferrocene-functionalized polydopamine film timely mediates M1-to-M2 macrophage polarization through adaptive wettability
Colloids Surf B Biointerfaces. 2024 Feb 25;236:113825. doi: 10.1016/j.colsurfb.2024.113825. Online ahead of print.ABSTRACTDynamical control of macrophage polarization from M1 (pro-inflammatory) to M2 (anti-inflammatory) at implant surfaces is essential for balancing innate immunity and tissue repair. In this aspect, the design of orthopedic implant that can response to inflammation microenvironment with transformation in surface properties has shown promising in timely driving M1-to-M2 macrophage transition. Considering excessive reactive oxygen species (ROS) contribute to macrophage M1 polarization and progression of infl...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Ying Shu Kai Li Jieping Li Yi Ding Guangzhi Yang Xuebin Zheng Source Type: research
A Cu( Ⅱ)-eluting coating through silk fibroin film on ZE21B alloy designed for in situ endotheliazation biofunction
In this study, the coating of copper loaded in silk fibroin is fabricated on biodegradable ZE21B alloy. Importantly, the different content of copper is set to investigate the effects of on the degradation performance and cell behavior of magnesium alloy. Through electrochemical and immersion experiments, it is found that high content of copper will accelerate the corrosion of magnesium alloy. The reason is the spontaneous micro-batteries between copper and magnesium with the different standard electrode potentials, that is, the galvanic corrosion accelerates the corrosion of magnesium alloy. Moreover, the coating formed th...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Qianying Jia Qinggong Jia Shijie Zhu Yufeng Zheng Shaokang Guan Source Type: research
Tumor microenvironment-activatable nanocatalysts with chemodynamic therapy and enhanced autophagy for specific treatment of oral squamous cell carcinoma
This study presents a targeted treatment strategy for OSCC tumors while sparing normal cells, offering a potential alternative in the realm of adjuvant therapy.PMID:38422665 | DOI:10.1016/j.colsurfb.2023.113713 (Source: Colloids and Surfaces)
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Hongtao Xu Chongyang Zheng Zhiyuan Zhang Xiaojuan Huang Source Type: research
Enhancing immune modulation and bone regeneration on titanium implants by alleviating the hypoxic microenvironment and releasing bioactive ions
Colloids Surf B Biointerfaces. 2024 Feb 17;236:113805. doi: 10.1016/j.colsurfb.2024.113805. Online ahead of print.ABSTRACTBone implantation inevitably causes damage to surrounding vasculature, resulting in a hypoxic microenvironment that hinders bone regeneration. Although titanium (Ti)-based devices are widely used as bone implants, their inherent bioinert surface leads to poor osteointegration. Herein, a strontium peroxide (SrO2)-decorated Ti implant, Ti_P@SrO2, was constructed through coating with poly-L-lactic acid (PLLA) to alleviate the hypoxic microenvironment and transform the bioinert surface of the implant into a...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Dongdong Zhang Han Liu Xiaodong Xue Feihong Liu Jun Wu Feng Peng Donghui Wang Haobo Pan Mei Li Source Type: research
Development of pH-freshness smart label based on gellan gum film incorporated with red cabbage anthocyanins extract and its application in postharvest mushroom
Colloids Surf B Biointerfaces. 2024 Feb 28;236:113830. doi: 10.1016/j.colsurfb.2024.113830. Online ahead of print.ABSTRACTNovel colorimetric films based on gellan gum (GG) containing red cabbage anthocyanins extract (RCAE) were prepared as pH-freshness smart labels for real-time visual detection of mushroom freshness. The GG/RCAE films had excellent pH and ammonia sensitivity. The GG/RCAE-0.2-0.3 films had the highest sensitivity to acetic acid. The SEM micrographs, AFM images, FT-IR and XRD spectra demonstrated that RCAE were successfully combined into the film-forming substrate. The incorporation of RCAE resulted in the ...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Shouqing Zhan Fangxuan Yi Fanyun Hou Lisha Song Xiuxiu Chen Hai Jiang Xiangbo Han Xia Sun Zhanli Liu Source Type: research
Ferrocene-functionalized polydopamine film timely mediates M1-to-M2 macrophage polarization through adaptive wettability
Colloids Surf B Biointerfaces. 2024 Feb 25;236:113825. doi: 10.1016/j.colsurfb.2024.113825. Online ahead of print.ABSTRACTDynamical control of macrophage polarization from M1 (pro-inflammatory) to M2 (anti-inflammatory) at implant surfaces is essential for balancing innate immunity and tissue repair. In this aspect, the design of orthopedic implant that can response to inflammation microenvironment with transformation in surface properties has shown promising in timely driving M1-to-M2 macrophage transition. Considering excessive reactive oxygen species (ROS) contribute to macrophage M1 polarization and progression of infl...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Ying Shu Kai Li Jieping Li Yi Ding Guangzhi Yang Xuebin Zheng Source Type: research
A Cu( Ⅱ)-eluting coating through silk fibroin film on ZE21B alloy designed for in situ endotheliazation biofunction
In this study, the coating of copper loaded in silk fibroin is fabricated on biodegradable ZE21B alloy. Importantly, the different content of copper is set to investigate the effects of on the degradation performance and cell behavior of magnesium alloy. Through electrochemical and immersion experiments, it is found that high content of copper will accelerate the corrosion of magnesium alloy. The reason is the spontaneous micro-batteries between copper and magnesium with the different standard electrode potentials, that is, the galvanic corrosion accelerates the corrosion of magnesium alloy. Moreover, the coating formed th...
Source: Colloids and Surfaces - February 29, 2024 Category: Biotechnology Authors: Qianying Jia Qinggong Jia Shijie Zhu Yufeng Zheng Shaokang Guan Source Type: research
Highly efficient GPCR immobilization with enhanced fouling resistance, salt tolerance, and chromatographic performance
Colloids Surf B Biointerfaces. 2024 Feb 22;236:113818. doi: 10.1016/j.colsurfb.2024.113818. Online ahead of print.ABSTRACTThe feasibility of immobilized protein-based biodetection relies critically on the activity of the immobilized proteins as well as the biocompatibility of the protein surface. Although many protein immobilization strategies have been developed with satisfied detection readout signals. Non-specific interactions caused by the protein-coating surface are still of great concern since they often interfere with or affect the reliability of detection. Herein, we developed a highly efficient G protein-coupled r...
Source: Colloids and Surfaces - February 28, 2024 Category: Biotechnology Authors: Sai Qiao Xinxin Zheng Yuanyuan Ou Ting Li Xue Zhao Jia Quan Xinfeng Zhao Qian Li Source Type: research
Instability of membranes containing ionizable cationic lipids: Effects of the repulsive range of headgroups and tail structures
Colloids Surf B Biointerfaces. 2024 Feb 20;236:113807. doi: 10.1016/j.colsurfb.2024.113807. Online ahead of print.ABSTRACTThe stability of membranes formed by ionizable cationic lipids, which constitute the primary components in lipid nanoparticles capable of endosomal escape, is explored using coarse-grained dissipative particle dynamics. Three types of ionizable model lipids with different tail structures are considered. Endosome acidification causes the ionization of lipids, leading to an increased repulsive range between their headgroups. When electrostatic repulsion is modeled as a conservative force with a long-range...
Source: Colloids and Surfaces - February 28, 2024 Category: Biotechnology Authors: Hao-Chun Huang Chih-Jung Lin Yu-Jane Sheng Heng-Kwong Tsao Source Type: research
Highly efficient GPCR immobilization with enhanced fouling resistance, salt tolerance, and chromatographic performance
Colloids Surf B Biointerfaces. 2024 Feb 22;236:113818. doi: 10.1016/j.colsurfb.2024.113818. Online ahead of print.ABSTRACTThe feasibility of immobilized protein-based biodetection relies critically on the activity of the immobilized proteins as well as the biocompatibility of the protein surface. Although many protein immobilization strategies have been developed with satisfied detection readout signals. Non-specific interactions caused by the protein-coating surface are still of great concern since they often interfere with or affect the reliability of detection. Herein, we developed a highly efficient G protein-coupled r...
Source: Colloids and Surfaces - February 28, 2024 Category: Biotechnology Authors: Sai Qiao Xinxin Zheng Yuanyuan Ou Ting Li Xue Zhao Jia Quan Xinfeng Zhao Qian Li Source Type: research
Instability of membranes containing ionizable cationic lipids: Effects of the repulsive range of headgroups and tail structures
Colloids Surf B Biointerfaces. 2024 Feb 20;236:113807. doi: 10.1016/j.colsurfb.2024.113807. Online ahead of print.ABSTRACTThe stability of membranes formed by ionizable cationic lipids, which constitute the primary components in lipid nanoparticles capable of endosomal escape, is explored using coarse-grained dissipative particle dynamics. Three types of ionizable model lipids with different tail structures are considered. Endosome acidification causes the ionization of lipids, leading to an increased repulsive range between their headgroups. When electrostatic repulsion is modeled as a conservative force with a long-range...
Source: Colloids and Surfaces - February 28, 2024 Category: Biotechnology Authors: Hao-Chun Huang Chih-Jung Lin Yu-Jane Sheng Heng-Kwong Tsao Source Type: research
