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APTES-mediated Cu 2 (OH) 3 (NO 3 ) nanomaterials on the surface of silicone catheters for abscess
This study presents a straightforward method for synthesizing antimicrobial silicone catheters containing copper nanomaterials using copper ions.PMID:38181690 | DOI:10.1016/j.colsurfb.2023.113734 (Source: Colloids and Surfaces)
Source: Colloids and Surfaces - January 5, 2024 Category: Biotechnology Authors: Yayun Wu Wanyue Fu Lin Liu Yechun Jiang Nian Liu Ming Fang Haoming Ye Jun Li Zhaoyou Chu Haisheng Qian Min Shao Source Type: research

Quality by design fostered fabrication of cabazitaxel loaded pH-responsive Improved nanotherapeutics against prostate cancer
Colloids Surf B Biointerfaces. 2023 Dec 27;234:113732. doi: 10.1016/j.colsurfb.2023.113732. Online ahead of print.ABSTRACTCabazitaxel has been approved for the treatment of prostate cancer since 2010. However, its poor solubility and permeability pitfalls prevent its accumulation at the target site and promote severe adverse effects. About 90% of prostate cancer (PCa) patients suffer from bone metastasis. This advent reports the development of CBZ-loaded pH-responsive polydopamine nanoparticles (CBZ NP) against metastatic PCa cells. Quality by design (QbD) and multivariate analysis tools were employed for the optimization ...
Source: Colloids and Surfaces - January 5, 2024 Category: Biotechnology Authors: Saurabh Shah Paras Famta Rahul Kumar Anamika Sharma Ganesh Vambhurkar Giriraj Pandey Gurpreet Singh Prakash Kumar Ankit Mehra Atul Mourya Dadi A Srinivasarao Akshay Shinde Sajja Bhanu Prasad Dharmendra Kumar Khatri Jitender Madan Saurabh Srivastava Source Type: research

The art of simplicity: Water-soluble porphyrin-like carbon dots self-assemble into mesmerizing red glow
Colloids Surf B Biointerfaces. 2023 Dec 22;234:113719. doi: 10.1016/j.colsurfb.2023.113719. Online ahead of print.ABSTRACTIn this new study, we present an intriguing development in the field of theranostics: the simplistic self-assembly of red-emissive amphiphilic porphyrin-like carbon dots (P-CDs). By harnessing their exceptional photophysical properties, we have revealed a strong candidate as the ideal photosensitizer (PS) for applications, particularly in the realm of imaging. Spanning a remarkable size average between 1-4 nm, these particles exhibit both highly stable and unparalleled emission characteristics between 6...
Source: Colloids and Surfaces - January 5, 2024 Category: Biotechnology Authors: Justin B Domena Braulio C L B Ferreira Jiuyan Chen M Bartoli A Tagliaferro Steven Vanni Regina M Graham Roger M Leblanc Source Type: research

Axial assembly of AuNR for tumor theranostics via Zn 2+ -GSH chelation induced degradation of AuNR@ZIF-8 heterostructures
Colloids Surf B Biointerfaces. 2023 Dec 12;234:113706. doi: 10.1016/j.colsurfb.2023.113706. Online ahead of print.ABSTRACTTumor microenvironment responsive photothermal ablation is a noninvasive and accurately targeted approach for cancer therapy. Herein, an intracellular directional assembly strategy for enhanced photothermal therapy (PTT) was realized by using ZIF-8 encapsulated Au nanorod (AuNR) heterostructure as the precursor of photothermal convertible material. The ZIF-8 shell selectively degraded in tumor cells upon the chelation between GSH and Zn2+, while the as-formed Zn(SG) connected the released AuNR in end-to...
Source: Colloids and Surfaces - January 4, 2024 Category: Biotechnology Authors: Tianyu Du Zewen Shi Xianbo Mou Yabin Zhu Source Type: research

Development of microemulgel formulations with varied permeation enhancers for transungual delivery of luliconazole in onychomycosis management
Colloids Surf B Biointerfaces. 2023 Dec 20;234:113718. doi: 10.1016/j.colsurfb.2023.113718. Online ahead of print.ABSTRACTLuliconazole-loaded microemulgels containing different permeation enhancers were formulated for transungual drug delivery for the management of onychomycosis, onychomycosis, which affects nails. The physicochemical properties like droplet size, zeta potential, pH, viscosity, spreadability, extrudability, oil binding capacity, drug content, and microscopic study were evaluated. The Pseudo-ternary phase diagram was constructed for the formulation of microemulsions (MEs) by keeping the Km ratio constant at...
Source: Colloids and Surfaces - January 4, 2024 Category: Biotechnology Authors: Yashwant Giri Sk Habibullah Pradyumna Kumar Dixit Gyanranjan Mahalik Biswaranjan Mohanty Amulyaratna Behera Source Type: research

Titanium-based substrate modified with nanoenzyme for accelerating the repair of bone defect
In conclusion, the modified Ti implant presented here had the effect of reducing OS and promoting osseointegration. Relevant research ideas and results provide new methods for the research and development of functional implants, which have potential application value in the field of orthopedics.PMID:38176336 | DOI:10.1016/j.colsurfb.2023.113737 (Source: Colloids and Surfaces)
Source: Colloids and Surfaces - January 4, 2024 Category: Biotechnology Authors: Yingying Tan Yao Ding Shaopeng Liu Peng Liu Kaiyong Cai Source Type: research

Design of fluorinated stealth poly( ε-caprolactone) nanocarriers
Colloids Surf B Biointerfaces. 2023 Dec 26;234:113730. doi: 10.1016/j.colsurfb.2023.113730. Online ahead of print.ABSTRACTThe covalent functionalization of polymers with fluorinated moieties represents a promising strategy for the development of multimodal systems. Moreover, polymer fluorination often endows the resulting nanocarriers with improved colloidal stability in the biological environment. In this work, we developed fluorinated pegylated (PEG) biodegradable poly(ε-caprolactone) (PCL) drug nanocarriers showing both high colloidal stability and stealth properties, as well as being (19F)-Nuclear Magnetic Resonance (...
Source: Colloids and Surfaces - January 4, 2024 Category: Biotechnology Authors: Beatrice Lucia Bona Prescillia Lagarrigue Cristina Chirizzi Maria Isabel Martinez Espinoza Christian Pipino Pierangelo Metrangolo Francesco Cellesi Francesca Baldelli Bombelli Source Type: research

Folic acid functionalized gadolinium-doped carbon dots as fluorescence / magnetic resonance imaging contrast agent for targeted imaging of liver cancer
This study provides a new idea for the application of Gd-CDs in FL and MR targeting imaging of liver cancer.PMID:38176338 | DOI:10.1016/j.colsurfb.2023.113721 (Source: Colloids and Surfaces)
Source: Colloids and Surfaces - January 4, 2024 Category: Biotechnology Authors: Jinglei Du Shizhao Zhou Yihua Ma Yingying Wei Qiang Li Hui Huang Lin Chen Yongzhen Yang Shiping Yu Source Type: research

The importance of cell uptake in photothermal treatments mediated by biomimetic magnetic nanoparticles
In this study, three different situations for photothermal treatments have been simulated to disentangle the effect of BMNPs cell uptake on cell viability after photothermal treatments. Human hepatoblastoma (HepG2) cell line was treated with suspensions of BMNPs, and protocols were developed to have only intracellular BMNPs, only extracellular BMNPs or both, followed by photothermal exposure of the treated cell cultures. Our data demonstrate that: (1) Although the heating efficiency of the photothermal agent is not altered by its location (intra/extracellular), the intracellular location of BMNPs is crucial to ensure the c...
Source: Colloids and Surfaces - December 31, 2023 Category: Biotechnology Authors: M L ázaro P Lupi áñez A Sola-Leyva T Pozo-Gualda F Oltolina M Jimenez-Carretero C Jimenez-Lopez M P Carrasco-Jim énez G R Iglesias Source Type: research

Dried blood drops on vertical surfaces
We present an experimental study of patterns formed by evaporating water-diluted blood droplets on a vertical surface. Three significant morphological features were observed in vertical droplet deposits: (1) The highest concentration of non-volatile molecules is consistently deposited in the lower part of the droplet, regardless of erythrocyte concentration. (2) The central region of deposits decreases rapidly with hematocrit; (3) At high erythrocyte concentrations (36-40% HCT), a broad coating of blood serum is produced in the upper part of the deposit. These findings are supported by the radial intensity profile, the rel...
Source: Colloids and Surfaces - December 31, 2023 Category: Biotechnology Authors: Roxana Belen P érez Hidalgo Jos ías N Molina-Courtois Yojana J P Carre ón Orlando D íaz-Hernández Jorge Gonz ález-Gutiérrez Source Type: research