Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research
Refractory hypothyroidism
DISCUSSION: The LT4 absorption test is a prompt and economical means to rule out true malabsorption, decrease unwarranted subspecialty referrals and validate the weight-adjusted LT4 dose reduction.PMID:38682851 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 29, 2024 Category: Pathology Authors: Y Y Lai S C Thambiah N Mohamed Mokhtar I N Samsudin Source Type: research
Efficacy of the Craniopharyngioma Resection via Expanded Endoscopic Endonasal Transsphenoidal Approach in the Treatment of Complex Craniopharyngioma and Its Effect on Pituitary Function and Complications of Patients
CONCLUSION: The craniopharyngioma resection via EETS has a significant therapeutic effect in complex craniopharyngioma with a high total tumor resection rate and clinical remission rate, which can protect the pituitary function of patients and provide more benefits for patients.PMID:38684506 | DOI:10.62713/aic.3145 (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - April 29, 2024 Category: Surgery Authors: Xiongjian Bu Source Type: research
Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
CONCLUSION: An individualized risk-based approach is recommended. Our study suggests that lymphovascular invasion may be associated with a higher risk of persistence/recurrence and should therefore be considered for decision making in children and adolescents with PTC.PMID:38683018 | DOI:10.4274/jcrpe.galenos.2024.2024-1-25 (Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology)
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - April 29, 2024 Category: Endocrinology Authors: Francisca Marques Puga Laura Correia In ês Vieira Joana Serra Caetano Rita Cardoso Isabel Dinis Alice Mirante Source Type: research
Correction: Assessment of the levels of interleukin-17 and interleukin-38 in thyroid-associated ophthalmopathy patients
(Source: International Ophthalmology)
Source: International Ophthalmology - April 29, 2024 Category: Opthalmology Source Type: research
Regional variations and sex-related differences of stiffness in human tracheal ligaments
ConclusionThese results reveal that there are regional and sex-related differences in the stiffness of human tracheal ligaments. (Source: Surgical and Radiologic Anatomy)
Source: Surgical and Radiologic Anatomy - April 29, 2024 Category: Anatomy Source Type: research
A Study to Evaluate TIRADS Scoring in the Management of Thyroid Nodules
Conclusion: The appropriate utilization of TIRADS can function as a dependable first method for evaluating thyroid nodules, although it is essential to supplement this approach with histological examinations in order to obtain a thorough understanding. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 29, 2024 Category: ENT & OMF Source Type: research
Contribution of CT scan to patient's radiation exposure in parathyroid SPECT/CT scintigraphy
This study aimed to estimate and optimize the contribution of computed tomography (CT) scan and scan range to effective dose (ED) in dual-phase MIBI SPECT/CT parathyroid scintigraphy. (Source: Radiography)
Source: Radiography - April 29, 2024 Category: Radiology Authors: S. Rep, L. Jensterle, U. Zde šar, K. Zaletel, P. Tomše, L. Ležaič Source Type: research
Nuclear features in thyroid cytology: features helpful for a morphological diagnosis in routine practice
This review article describes nuclear features of a range of thyroid lesions to enable confident diagnosis in a multidisciplinary thyroid cancer setting. It is hoped that this will serve as a handy aide-m émoire when faced with diagnosis of thyroid FNA (fine needle aspiration) cytology in day-to-day practice. The existing literature has been reviewed to give the reader an overview of the classification systems in thyroid cytology and various entities described therein. The lesions are broadly catego rised as benign, malignant, and indeterminate. (Source: Diagnostic Histopathology)
Source: Diagnostic Histopathology - April 29, 2024 Category: Pathology Authors: Priya Bhagwat, Sabine Pomplun Tags: Mini-symposium: endocrine pathology Source Type: research
Triiodothyronine Supplementation for Children Undergoing Cardiopulmonary Bypass: A Meta-Analysis
AbstractSpecific pediatric populations have exhibited disparate responses to triiodothyronine (T3) repletion during and after cardiopulmonary bypass (CPB). Objective: To determine if T3 supplementation improves outcomes in children undergoing CPB. We searched randomized controlled trials (RCT) evaluating T3 supplementation in children aged 0 –3 years undergoing CPB between 1/1/2000 and 1/31/2022. We calculated Hazard ratios (HR) for time to extubation (TTE), ICU length of stay (LOS), and hospital LOS. 5 RCTs met inclusion criteria with available patient-level data. Two were performed in United States (US) and 3 in Indon...
Source: Mammalian Genome - April 28, 2024 Category: Genetics & Stem Cells Source Type: research
Biological functions of LncRNA SNHG14 in the development of thyroid cancer cells via targeting miR-206
This study aimed to determine lncRNA SNHG14 and miR-206 in Thyroid Cancer ( TC) and to explore the related mechanisms. Sixty-four samples of thyroid tissue were collected from patients with TC. TC cell lines and a normal human thyroid cell line (HTori-3) were bought. lncRNA SNHG14-siRNA (si-lncRNA SNHG14), lncRNA SNHG14-shRNA (sh-lncRNA SNHG14), blank plasmid (siRNA-NC), miR-206-inhibitor, miR-206-mimics were transfected into BHT101 and Ocut-2C cells. qRT-PCR quantified the expression of lncRNA SNHG14 and miR-206, and the expression of vimentin, Snail, N-cadherin, Slug, E-cadherin and ZO-1 proteins were identified via WB. ...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Yiming Sang Rui Min Tao Huang Jizong Zhang Source Type: research
Naive and regulatory B-cell transcription patterns guide the increased risk of papillary thyroid carcinoma in obesity
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):118-126. doi: 10.14715/cmb/2024.70.4.19.ABSTRACTA growing number of studies suggest a positive association between obesity and the high incidence of papillary thyroid cancer (PTC), suggesting that the abnormal levels of adipokines associated with obesity may be a risk factor for these aggressive thyroid cancers, but the underlying regulatory mechanisms are not yet clear. We downloaded bulk RNA sequence data for subcutaneous adipose tissue (SAT) in obesity and healthy population and tumor tissues of PTC from GEO database. Through analysis of Differential Expression Genes (DE...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Zihui Yu Ziying Xu Shang Li Ziyan Tian Jing Yuan Source Type: research
Cardiac hypertrophy that affects hyperthyroidism occurs independently of the NLRP3 inflammasome
Pflugers Arch. 2024 Apr 29. doi: 10.1007/s00424-024-02965-6. Online ahead of print.ABSTRACTCardiac hypertrophy (CH) is an adaptive response to maintain cardiac function; however, persistent stress responses lead to contractile dysfunction and heart failure. Although inflammation is involved in these processes, the mechanisms that control cardiac inflammation and hypertrophy still need to be clarified. The NLRP3 inflammasome is a cytosolic multiprotein complex that mediates IL-1β production. The priming step of NLRP3 is essential for increasing the expression of its components and occurs following NF-κB activation. Hypert...
Source: Pflugers Archiv : European Journal of Physiology - April 28, 2024 Category: Physiology Authors: Aline Cristina Parletta Gabriela Cavazza Cerri Claudia Ribeiro Borba Gasparini Karine Panico Denival Nascimento Vieira-Junior Larissa Maria Zacarias-Rodrigues Nathalia Senger Amanda de Almeida Silva Marina Fevereiro Gabriela Placon á Diniz Maria Cl áudi Source Type: research
Presacral Neuroendocrine Neoplasms: A Multi-site Review of Surgical Outcomes
CONCLUSION: The study underscores the complex management of PNENs and emphasizes the need for multicenter research to better understand and manage these tumors. It provides valuable insights into surgical outcomes, recurrence rates, and overall survival, guiding future treatment strategies for PNEN patients.PMID:38679679 | DOI:10.1245/s10434-024-15328-3 (Source: Ann Oncol)
Source: Ann Oncol - April 28, 2024 Category: Cancer & Oncology Authors: Tommaso Violante Brenda Murphy Davide Ferrari Rondell P Graham Patrick Navin Amit Merchea David W Larson Eric J Dozois Thorvardur R Halfdanarson William R Perry Source Type: research
From Bench-to-Bedside: How Artificial Intelligence Is Changing Thyroid Nodule Diagnostics
CONCLUSIONS: Models predominantly used ultrasound images to predict malignancy. Of four FDA-approved products, only S-Detect was extensively validated. Implementing an AI model locally requires data sanitization and re-validation to ensure appropriate clinical performance.PMID:38679750 | DOI:10.1210/clinem/dgae277 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 28, 2024 Category: Endocrinology Authors: Vivek R Sant Ashwath Radhachandran Vedrana Ivezic Denise T Lee Masha J Livhits James X Wu Rinat Masamed Corey W Arnold Michael W Yeh William Speier Source Type: research
