Efficacy and safety of fibrin sealant application in patients undergoing thyroidectomy: a systematic review and meta-analysis
BMC Surg. 2024 Apr 24;24(1):122. doi: 10.1186/s12893-024-02414-2.ABSTRACTVarious studies have focused on the application of fibrin sealants (FS) in thyroid surgery. Utilizing a meta-analysis, this systematic review analyzed the findings of recent randomized controlled trials on the safety and efficacy of FS in patients who underwent thyroidectomy. The Cochrane Library, Web of Science, Embase, PubMed, and Medline databases were searched for relevant studies, without any language restrictions. Seven randomized controlled trials were included in the originally identified 69 studies. Overall, 652 patients received FS during th...
Source: Cancer Control - April 24, 2024 Category: Cancer & Oncology Authors: XiaoGang Zheng Fan Wang Yong Cheng Su Chao Yang Xu Ming Zheng Wang Source Type: research

Thyroid Cancer and Endocrine Disruptive Chemicals: A Case-Control Study on Per-fluoroalkyl Substances (PFAS) and Other Persistent Organic Pollutants (POPs)
CONCLUSIONS: Our study suggests, for the first time in a case-control population, that exposure to some PFAS and PCBs associates with TC and some clinical and molecular features. On the contrary, an inverse correlation was found with both PFHxS and pollutants' mixture, likely due to a potential reverse causality.PMID:38657654 | DOI:10.1530/ETJ-23-0192 (Source: Cancer Control)
Source: Cancer Control - April 24, 2024 Category: Cancer & Oncology Authors: Valentina Cirello Marina Lugaresi Claudia Moneta Patrice Dufour Alessandro Manzo Erika Carbone Carla Colombo Laura Fugazzola Corinne Charlier Catherine Pirard Source Type: research

< em > TAF1 < /em > is needed for the proliferation and maturation of thyroid follicle cells < em > via < /em > Notch signaling
This study showed that TAF1 promoted Notch signaling and that this association played a pivotal role in thyroid development.PMID:38656129 | DOI:10.1152/ajpendo.00403.2023 (Source: American Journal of Physiology. Endocrinology and Metabolism)
Source: American Journal of Physiology. Endocrinology and Metabolism - April 24, 2024 Category: Physiology Authors: Caoxu Zhang Liu Yang Haiyang Zhang Fengyao Wu Yue Zhang Kaiwen Zhang Chenyang Wu Rui Li Mei Dong Shuangxia Zhao Huaidong Song Source Type: research

Patterns in the Reporting of Aggressive Histologic Subtypes in Papillary Thyroid Cancer
CONCLUSIONS: Aggressive subtypes of PTC are associated with worse outcomes. Academic and other facilities in the Middle Atlantic were more likely to report aPTC. This suggests the need for further evaluation of environmental or geographic factors versus a need for increased awareness and more accurate diagnosis of these subtypes.PMID:38657351 | DOI:10.1016/j.jss.2024.03.023 (Source: Cell Research)
Source: Cell Research - April 24, 2024 Category: Cytology Authors: Yeon J Lee Caitlin E Egan Jacques A Greenberg Teagan Marshall Abhinay Tumati Brendan M Finnerty Toni Beninato Rasa Zarnegar Thomas J Fahey Minerva A Romero Arenas Source Type: research

Effectiveness of prognostic nutritional index in predicting overall survival and evaluating immunotherapy response in anaplastic thyroid carcinoma
ConclusionPNI is an independent predictor of overall survival and holds the potential to serve as a valuable indicator for assessing and predicting immunotherapy efficacy in ATC patients. (Source: Endocrine)
Source: Endocrine - April 24, 2024 Category: Endocrinology Source Type: research