Correction: Comparative evaluation of shear wave elastography elasticity values in thyroid nodules with cytology results and TI-RADS scoring in differentiation of benign –malignant nodules
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research
PD ‐1 inhibition with retifanlimab and/or arginase inhibition with INCB001158 in Japanese patients with solid tumors: A phase I study
ConclusionRetifanlimab, INCB001158, and their combination had acceptable safety profiles. Promising retifanlimab antitumor activity warrants further investigation in Japanese patients. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Yasutoshi Kuboki,
Takafumi Koyama,
Nobuaki Matsubara,
Yoichi Naito,
Shunsuke Kondo,
Kenichi Harano,
Kan Yonemori,
Kiyotaka Yoh,
Yuan Gu,
Tetsuya Mita,
Xuejun Chen,
Eiji Ueda,
Noboru Yamamoto,
Toshihiko Doi,
Toshio Shimizu Tags: RESEARCH ARTICLE Source Type: research
Obesity and thyroid cancer: unraveling the connection through a systematic review and meta-analysis of cohort studies
ConclusionThe synthesis of 27 studies with diverse designs and populations underscores a robust positive association between adiposity and TC risk, providing compelling evidence for the potential role of increased adiposity in TC development. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 23, 2024 Category: Endocrinology Source Type: research
Intraluminal extension of papillary thyroid carcinoma into the Internal Jugular Vein; a case report
Papillary thyroid carcinoma (PTC), being the most common thyroid malignancy, is a slow-growing tumor and is usually limited to the thyroid. Extra thyroid extension is uncommon; besides, invasion to the vascula... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - April 23, 2024 Category: Endocrinology Authors: Firouze Jafari, Ali Taheri Akerdi, Hossein Abdolrahimzadeh Fard, Mehrdad karajizadeh and Shahram Paydar Tags: Case Report Source Type: research
Growth impairment in children with atrophic autoimmune thyroiditis and pituitary hyperplasia
Atrophic autoimmune thyroiditis (AAT) is a rare phenotype of autoimmune thyroiditis (AT) in pediatric age. AAT occurs without thyroid enlargement leading to a delay in its diagnosis. Growth impairment is infre... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 23, 2024 Category: Pediatrics Authors: Domenico Corica, Tiziana Abbate, Anna Malgorzata Kucharska, Malgorzata Wojcik, Francesco Vierucci, Mariella Valenzise, Alessandra Li Pomi, Giorgia Pepe, Gerdi Tuli, Beata Pyrzak, Tommaso Aversa and Malgorzata Wasniewska Tags: Research Source Type: research
CircPHGDH downregulation decreases papillary thyroid cancer progression through miR-122-5p/PKM2 axis
Although papillary thyroid carcinoma (PTC) has a favorable prognosis, it could affect patient life quality and become a serious threat because of invasion and metastasis. Many investigations have suggested tha... (Source: BMC Cancer)
Source: BMC Cancer - April 23, 2024 Category: Cancer & Oncology Authors: Jiying Shen, Zhirong Ma, Jin Yang, Tianzhen Qu, Yu Xia, Yingjie Xu, Ming Zhou and Weiwei Liu Tags: Research Source Type: research
Unusually elongated superior thyroid cornu associated with recurrent cerebral embolisms
AbstractThe superior thyroid cornu (STC) is a normal anatomic structure that forms part of the thyroid cartilage. Here, we report a patient with unusually elongated and ossified STC that might result in recurrent cerebral embolisms. During a second endovascular therapy for recurrent middle cerebral artery embolism, a segment with an irregular filling defect was noted in the internal carotid artery (ICA), at the C1 level. This defect was unnoticed during the initial endovascular procedure. Three-dimensional computed tomography angiography performed after the second endovascular procedure revealed an ICA segment located betw...
Source: Surgical and Radiologic Anatomy - April 23, 2024 Category: Anatomy Source Type: research
Growth impairment in children with atrophic autoimmune thyroiditis and pituitary hyperplasia
ConclusionsThis is the largest pediatric cohort with severe autoimmune primary hypothyroidism without goiter, but with pituitary hyperplasia in which significant growth impairment was the most evident presenting sign. AAT phenotype might be correlated with this specific clinical presentation. In youths with growth impairment, hypothyroidism should always be excluded even in the absence of clear clinical signs of dysthyroidism. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 23, 2024 Category: Pediatrics Source Type: research
Risks of suboptimal and excessive thyroid hormone replacement across ages
ConclusionSuboptimal and excessive LT4 replacement of the preventable non-communicable disease hypothyroidism requires more focus from the healthcare system and from the global political systems to prevent the personally devastating and socioeconomically challenging consequences. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research
Artificial intelligence in endocrinology: a comprehensive review
ConclusionsBy embracing AI in endocrinology, a future can be envisioned where medical professionals and AI systems synergistically collaborate, ultimately enhancing the lives of individuals affected by endocrine disorders. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research
Experimental rat models for Hashimoto ’s thyroiditis
ConclusionTwo rat models of autoimmune thyroiditis were obtained. EAT caused in Wistar rats by immunization with rat Tg is similar to Hashimoto ’s thyroiditis. EAT induced with porcine Tg was accompanied by oxyphil cell metaplasia in the parathyroids and hypocalcemia. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research
Metabolite signature of human malignant thyroid tissue: A systematic review and meta ‐analysis
ConclusionIt appears that the field of TC metabolomics will experience notable advancement, leading to the discovery of trustworthy diagnostic and prognostic biomarkers. (Source: Cancer Medicine)
Source: Cancer Medicine - April 22, 2024 Category: Cancer & Oncology Authors: S. Adeleh Razavi,
Babak Khorsand,
Pouya Salehipour,
Mehdi Hedayati Tags: REVIEW Source Type: research
Thyroid dysfunction in nonvalvular atrial fibrillation and clinical outcomes
ConclusionLow T3 syndrome are linked to an increased risk of heart failure and all-cause death in individuals with NVAF. And Patients with NVAF and low TT3 levels have a higher risk of thromboembolism. (Source: Endocrine)
Source: Endocrine - April 22, 2024 Category: Endocrinology Source Type: research
Acutely shaky hand
Clinical introduction A 57-year-old man presented acutely with involuntary movements of his left hand. He had hypertension, chronic kidney disease and chronic obstructive pulmonary disease. These movements were best described as sudden, recurrent and arrhythmic loss of tone and power of the left wrist and fingers (video 1). They were most prominent when extending the left wrist, but were absent when the arms were at rest and were not elsewhere. There were no additional neurological deficits. Serum urea, ammonia, sodium, potassium, calcium, magnesium, phosphate and glucose levels were normal. His haematological profile, inf...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Tan, Y.-J., Teo, C. H., Chan, C. Tags: EMJ Image Challenge Source Type: research
Imaging findings of children with PTEN-related hamartoma tumor syndrome: a 20-year multicentric pediatric cohort
ConclusionBrain abnormalities, benign non-vascular soft tissue abnormalities, and vascular anomalies are commonly seen in children and adolescents with PTEN-related hamartoma tumor syndrome. However, malignancies involving the thyroid gland are not uncommon. Familiarity with the phenotype of PTEN-related hamartoma tumor syndrome in the pediatric population can improve diagnosis and prompt appropriate clinical surveillance of abnormal findings that warrant further management.Graphical abstract (Source: Pediatric Radiology)
Source: Pediatric Radiology - April 22, 2024 Category: Radiology Source Type: research
