The rate of endophthalmitis after pars plana vitrectomy and its risk factors
ConclusionOur results indicated low incidence of endophthalmitis after pars plana vitrectomy comparable to previous studies which resulted in poor visual acuity. It seems that not using tamponade might increase the risk of endophthalmitis among these patients. (Source: International Ophthalmology)
Source: International Ophthalmology - May 11, 2018 Category: Opthalmology Source Type: research

Ocular surface squamous neoplasia: analysis based on the 8th American Joint Committee on Cancer classification
AbstractPurposeTo evaluate outcomes of ocular surface squamous neoplasia (OSSN) based on American Joint Committee on Cancer (AJCC), 8th edition classification.MethodsRetrospective, non-randomized interventional case series of 127 patients (136 eyes) with OSSN.ResultsOn the basis of the AJCC (eighth edition), OSSN was classified as per T category as Tis (n = 14, 10%), T1 (n = 0), T2 (n = 4, 3%), T3 (n = 113, 83%), and T4 (n = 5, 4%). The following parameters increased with increasing T category: mean age at presentation at 37 years for Tis, 43 y...
Source: International Ophthalmology - May 10, 2018 Category: Opthalmology Source Type: research

Structural changes of macula and optic disk of the fellow eye in patients with nonarteritic anterior ischemic optic neuropathy
This study included 28 patients and age, sex and refraction-matched 28 control subjects. Mean GCC thickness and peripapillary RNFL thickness in four quadrants measured by cirrus SD-OCT were evaluated in both AE and FE of patients and CE. In addition, optic disk measurements obtained with OCT were evaluated.ResultsMean GCC thickness was significantly lower in AE compared with both FE and CE (P  
Source: International Ophthalmology - May 10, 2018 Category: Opthalmology Source Type: research

Functional and morphological assessment of ocular structures and follow-up of patients with early-stage Parkinson ’s disease
ConclusionStructural and functional disorders shown as electro-physiologically and morphologically exist in different parts of visual pathways in early-stage Parkinson ’s disease. (Source: International Ophthalmology)
Source: International Ophthalmology - May 9, 2018 Category: Opthalmology Source Type: research

Accuracy of ultra-wide-field fundus ophthalmoscopy-assisted deep learning, a machine-learning technology, for detecting age-related macular degeneration
ConclusionA combination of DCNN with Optos images is not better than a medical examination; however, it can identify exudative AMD with a high level of accuracy. Our system is considered useful for screening and telemedicine. (Source: International Ophthalmology)
Source: International Ophthalmology - May 9, 2018 Category: Opthalmology Source Type: research

Microstructural retinal regeneration after internal limiting membrane flap surgery for repair of large macular holes: a 1-year follow-up study
ConclusionsLong-term results show further improvement in the best-corrected visual acuity as well as further microstructural regeneration of the retina and decrease in ellipsoid zone defects over time. The exact mechanism, which promotes closure of the macular hole and reconstruction of the ellipsoid zone after internal Limiting Membrane autograft surgery, still remains unknown. (Source: International Ophthalmology)
Source: International Ophthalmology - May 9, 2018 Category: Opthalmology Source Type: research

Comparison of pain after subepithelial versus conventional accelerated corneal collagen cross-linking for keratoconus
ConclusionsSubepithelial accelerated CXL significantly improved postoperative pain as well as reduced the epithelial healing time for the treatment of keratoconus. (Source: International Ophthalmology)
Source: International Ophthalmology - May 7, 2018 Category: Opthalmology Source Type: research

Comparison of densitometric profile after deep lamellar keratoplasty with two different techniques for treatment of keratoconus
ConclusionDensitometric profiles were identical in both methods in visually important zones so as visual and refractive outcomes. (Source: International Ophthalmology)
Source: International Ophthalmology - May 5, 2018 Category: Opthalmology Source Type: research

Nd:YAG laser for epithelial ingrowth after laser in situ keratomileusis
ConclusionYAG laser is a simple, effective outpatient procedure for the management of epithelial ingrowth after LASIK. (Source: International Ophthalmology)
Source: International Ophthalmology - May 4, 2018 Category: Opthalmology Source Type: research

Pigment dispersion syndrome and pigmentary glaucoma: a review and update
ConclusionsThe differential diagnosis of PDS with other disorders can be challenging and awareness of the condition together with meticulous ophthalmologic examination allows early diagnosis followed by appropriate management strategies. The present review is a comprehensive report on the clinical characteristics, pathogenesis, current management, and status quo of PDS and PG. (Source: International Ophthalmology)
Source: International Ophthalmology - May 2, 2018 Category: Opthalmology Source Type: research

Histomorphometric analysis of the choroid of donkeys, buffalos, camels and dogs
Conclusion In conclusion, these variations might be related to the different lifestyles and visual behavior of the investigated animals. (Source: International Ophthalmology)
Source: International Ophthalmology - May 2, 2018 Category: Opthalmology Source Type: research

Case report: acute hydrops and spontaneous corneal perforation in a patient with keratoconus treated with colchicine for familial Mediterranean fever
ConclusionColchicine treatment may have had a role in the pathogenesis of this rare case. (Source: International Ophthalmology)
Source: International Ophthalmology - April 30, 2018 Category: Opthalmology Source Type: research

The ophthalmic diagnosis and management of four siblings with Werner syndrome
ConclusionFurther study is needed to elucidate the precise role of retinal WRN protein expression in the development of CMO in those with Werner syndrome. A tailored and more successful approach to the treatment of CMO in such patients may result. (Source: International Ophthalmology)
Source: International Ophthalmology - April 28, 2018 Category: Opthalmology Source Type: research

A study of changes in levator muscle in congenital ptosis
ConclusionFibrocollagenous tissue predominated in all the cases, and muscle fibers detected correlated inversely with the severity of ptosis. The absence of degenerating, regenerating fibers and inflammatory cells supported the theory of dysgenesis of muscle. However, internalization of nucleus seen in all the subtypes is a feature favoring dystrophy. (Source: International Ophthalmology)
Source: International Ophthalmology - April 28, 2018 Category: Opthalmology Source Type: research

Keratomycosis due to Tintelnotia destructans refractory to common therapy treated successfully with systemic and local terbinafine in combination with polyhexamethylene biguanide
ConclusionsTerbinafine might be considered as a therapeutic option in severe cases of fungal keratitis refractory to common antifungal therapy. (Source: International Ophthalmology)
Source: International Ophthalmology - April 28, 2018 Category: Opthalmology Source Type: research

Hook and flip technique: for phacoemulsification in non-rotating nuclei and posterior polar cataracts
Conclusion‘Hook and flip technique’ thus proves useful whenever dismantling difficulties are encountered during phacoemulsification. (Source: International Ophthalmology)
Source: International Ophthalmology - April 27, 2018 Category: Opthalmology Source Type: research

Factors influencing stereopsis in patients with both refractive accommodative esotropia and amblyopia
ConclusionIO overaction, BCVA in amblyopic eyes, VAD and AOF were found to be potential risk factors for the development of stereopsis in patients with both RAE and amblyopia. (Source: International Ophthalmology)
Source: International Ophthalmology - April 27, 2018 Category: Opthalmology Source Type: research

Recurrent corneal erosion caused by retained sutures in blepharoplasty
ConclusionsSuture exposure may occur several years after blepharoplasty and could cause RCE. Thorough exploration of the fornix by double eyelid eversion can identify the hidden sutures in such patients. (Source: International Ophthalmology)
Source: International Ophthalmology - April 27, 2018 Category: Opthalmology Source Type: research

Comparison of anterior segment parameters and axial length measurements performed on a Scheimpflug device with biometry function and a reference optical biometer
AbstractPurposeTo compare measurements of axial length (AL), corneal curvature (K), anterior chamber depth (ACD) and white-to-white (WTW) distance on a new device combining Scheimpflug camera and partial coherence interferometry (Pentacam AXL) with a reference optical biometer (IOL Master 500). To evaluate differences between IOL power calculations based on the two biometers.MethodsNinety-seven eyes of 97 consecutive cataract or refractive lens exchange patients were examined preoperatively on IOL Master 500 and Pentacam AXL units. Comparisons between two devices were performed for AL, K, ACD and WTW. Intraocular lens (IOL...
Source: International Ophthalmology - April 26, 2018 Category: Opthalmology Source Type: research

Effect of metronidazole ophthalmic solution on corneal neovascularization in a rat model
AbstractPurposeTo evaluate the effect of metronidazole ophthalmic solutions on corneal neovascularization (CNV) in a rat model.MethodsA chemical burn was created in the right central cornea of 40 rats. Animals were randomized and distributed into four study groups (n = 10 rats per group) designated Met_0.1%, Met_0.5%, sham, and untreated groups. Chemical-burned corneas in the Met_0.1% and Met_0.5% groups received ophthalmic solutions of 0.1 and 0.5% metronidazole, respectively. Corneas in the sham group received phosphate-buffered saline (metronidazole dilu ent). All treated eyes received ophthalmic solution ...
Source: International Ophthalmology - April 26, 2018 Category: Opthalmology Source Type: research

Ocular sebaceous gland carcinoma: an update of the literature
ConclusionOcular SGC is an aggressive tumor associated with poor prognosis. Early identification and appropriate treatment may help improve the prognosis. New insight into its pathogenesis and the immunohistochemical profile may lead to the development of new effective treatment strategies, along with traditional therapies. (Source: International Ophthalmology)
Source: International Ophthalmology - April 25, 2018 Category: Opthalmology Source Type: research

Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma
ConclusionThe additional benefit of single dose of intraoperative bevacizumab was not observed in trabeculectomy with 5-FU in PXG. (Source: International Ophthalmology)
Source: International Ophthalmology - April 25, 2018 Category: Opthalmology Source Type: research

Influence of glaucoma surgery on the ocular surface using oculus keratograph
AbstractPurposeTo investigate the influence of trabeculectomy and phacotrabeculectomy on the ocular surface.DesignRetrospective, case –control study.MethodsEighty-one samples without dry eyes were recruited and divided into three groups, including phacoemulsification group (N = 30) as control group, trabeculectomy group (N = 27) and phacotrabeculectomy group (N = 24) as study groups. Ocular surface parameters, including noninvasive keratograph first (NifBUT) and average (NiaBUT) tear film breakup time, tear meniscus height (TMH) and corneal fluorescein stain (CFS), were estimated preoper...
Source: International Ophthalmology - April 24, 2018 Category: Opthalmology Source Type: research

Ocular surface squamous neoplasia in a setting of fungal keratitis: a rare co-occurrence
(Source: International Ophthalmology)
Source: International Ophthalmology - April 24, 2018 Category: Opthalmology Source Type: research

Trans-epithelial corneal collagen cross-linking with iontophoresis for progressive keratoconus
AbstractPurposeTo evaluate the efficacy of trans-epithelial corneal collagen cross-linking (CXL) with Iontophoresis among patients with progressive keratoconus.MethodsIt is a prospective interventional study, which is based on 41 eyes of 23 patients, suffering from progressive keratoconus and treated with trans-epithelial corneal cross-linking, using iontophoresis with ETDA and trometamol-enriched riboflavin 5 phosphates 0.1% hypotonic solution (Ricrolin+, Soot Italia SpA, Italy).ResultsThe mean of uncorrected distance visual acuity and best corrected distant visual acuity was improved at 6  months with statistically ...
Source: International Ophthalmology - April 19, 2018 Category: Opthalmology Source Type: research

Changes in choroidal thickness following trabeculectomy and its correlation with the decline in intraocular pressure
ConclusionChoroidal thickness appears to increase temporarily after trabeculectomy and these changes were not correlated with the decline in intraocular pressure. Further research is required to fully understand this phenomenon. (Source: International Ophthalmology)
Source: International Ophthalmology - April 16, 2018 Category: Opthalmology Source Type: research

Confocal scanning laser microscopy in patients with postoperative endophthalmitis
AbstractPurposeTo investigate alterations of corneal layers in eyes treated for acute postoperative endophthalmitis.MethodsIn this retrospective, nonrandomized comparative study, eyes treated with 25 gauge pars plana vitrectomy (PPV) for acute post-cataract endophthalmitis (group A) were compared to eyes receiving uneventful cataract surgery (group B) and uneventful 25 gauge PPV for epiretinal membrane (group C). After a minimum follow-up of 8  months from last surgical procedure, laser scanning in vivo confocal microscopy (IVCM) was performed.ResultsTwelve eyes for each group were recruited. Comparing study eyes with...
Source: International Ophthalmology - April 13, 2018 Category: Opthalmology Source Type: research

Evaluation of clinical outcomes following implantation of a sub-2-mm hydrophilic acrylic MICS intraocular lens
ConclusionsThe new MICS IOL provided excellent visual outcomes and was safe and effective for the sub-2-mm procedure. The MICS IOL demonstrated long-term centration, stability and a low rate of PCO development. (Source: International Ophthalmology)
Source: International Ophthalmology - April 13, 2018 Category: Opthalmology Source Type: research

Predictive value of spectral-domain optical coherence tomography features in assessment of visual prognosis in eyes with acute welding arc maculopathy
AbstractObjectiveTo observe spectral-domain optical coherence tomography (SD-OCT) features and to determine whether baseline OCT features can be used as predictors of visual acuity outcome in eyes with acute welding arc maculopathy.MethodsThis retrospective study enrolled twenty-two eyes of eleven subjects with acute welding arc maculopathy. All subjects were evaluated by SD-OCT at baseline and final visit. The involved parameters included best-corrected visual acuity (BCVA), central macular thickness (CMT), the length of ellipsoid zone (EZ) defects, the greatest linear dimension (GLD) of outer retinal lesions, EZ reflecti...
Source: International Ophthalmology - April 12, 2018 Category: Opthalmology Source Type: research

Spare some internal limiting membrane for later: free ILM patch and neurosensory retina graft
DiscussionInternal limiting membrane patch can be considered in chronic macular holes. It may not be an option in cases of over-enlargement of a previous peel; free autologous neurosensory retina patch may be a valid alternative in such cases. (Source: International Ophthalmology)
Source: International Ophthalmology - April 10, 2018 Category: Opthalmology Source Type: research

Endothelial keratoplasty in eyes with a retained angle-supported intraocular lens
ConclusionThe presented short-term outcomes suggest that both DMEK and DSAEK are feasible in eyes with an angle-supported acIOL yielding an acceptable graft survival rate in the first postoperative year. (Source: International Ophthalmology)
Source: International Ophthalmology - April 4, 2018 Category: Opthalmology Source Type: research

Inter- and intraobserver repeatability and reproducibility of choroidal thickness measurements using two different methods
ConclusionChoroidal thickness measurements by EDI-OCT showed a high inter- and intraobserver reproducibility. (Source: International Ophthalmology)
Source: International Ophthalmology - March 31, 2018 Category: Opthalmology Source Type: research

The relation between retrobulbar blood flow and posterior ocular changes measured using spectral-domain optical coherence tomography in patients with obstructive sleep apnea syndrome
ConclusionPI and RI values of the PCA, which supplies the optic nerve, show a linear increase as the apnea hypoxia index values in OSAS. As the grade of OSAS improves, this situation leads to a more serious ischemic optic neuropathy. Furthermore, the prevalence of glaucoma in this study is found to be higher in the severe OSAS group. (Source: International Ophthalmology)
Source: International Ophthalmology - March 29, 2018 Category: Opthalmology Source Type: research

Sterile keratitis after uneventful corneal collagen cross-linking in a patient with Axenfeld-Rieger syndrome
ConclusionsThe mechanism by which the sterile keratitis occurs following CXL remains unclear. For our case, the reason of post-CXL sterile keratitis could be considered as an immune response due to the staphylococcal antigens. Furthermore, the possible developmental disturbance of corneal stroma in ARS might have contributed to the development of post-CXL sterile keratitis. (Source: International Ophthalmology)
Source: International Ophthalmology - March 28, 2018 Category: Opthalmology Source Type: research

Repair of angle recession prevents pupillary capture of intrasclerally fixed intraocular lenses
ConclusionIn select cases, repairing angle recession may be useful for preventing pupillary capture after IOL suturing and intrascleral fixation. (Source: International Ophthalmology)
Source: International Ophthalmology - March 28, 2018 Category: Opthalmology Source Type: research

Ocular surface and respiratory tract damages from occupational, sub-chronic exposure to fluorspar: case report and other considerations
ConclusionsThe present work remarks the importance of using protective equipment for preventing ocular and respiratory tract damages in workers occupationally exposed to the ‘acid-grade fluorite’. (Source: International Ophthalmology)
Source: International Ophthalmology - March 28, 2018 Category: Opthalmology Source Type: research

Case series of coexistence of polypoidal choroidal vasculopathy with other rare fundus diseases
ConclusionWe reported rare fundus comorbidities of PCV in a large Chinese cohort. These comorbidities included myelinated nerve fiber, branch retinal vein occlusion and retinal angiomatous proliferation. The combination might constitute an accidental occurrence. (Source: International Ophthalmology)
Source: International Ophthalmology - March 28, 2018 Category: Opthalmology Source Type: research

Resolution of arterial aneurysms in idiopathic retinal vasculitis, aneurysms and neuroretinitis: a case report and review of literature
ConclusionsThis case demonstrates previously unreported reversibility of arterial aneurysms with steroid therapy alone in early stages of IRVAN. (Source: International Ophthalmology)
Source: International Ophthalmology - March 28, 2018 Category: Opthalmology Source Type: research

Outcomes of presbyopia-correcting intraocular lenses after laser in situ keratomileusis
ConclusionIn conclusion, in post-myopic LASIK eyes, AT LISA tri839MP provides a good visual outcome at both near and distance, but is more predictable at near than at distance. There is a myopic shift in the postoperative SE. Visual quality is satisfactory and has not been exacerbated. Most patients can remain to be spectacles free at all distances. (Source: International Ophthalmology)
Source: International Ophthalmology - March 28, 2018 Category: Opthalmology Source Type: research

The effects of chalazion surgery on intraocular pressure and corneal topography
ConclusionTo the best of our knowledge, this is the first report to suggest that IOP and CKI are decreased after the removal of upper eyelid chalazion. (Source: International Ophthalmology)
Source: International Ophthalmology - March 28, 2018 Category: Opthalmology Source Type: research

Autologous neurosensory retinal free patch transplantation for persistent full-thickness macular hole
ConclusionsANRFP transplantation may represent an innovative technique for persistent iFTMH treatment. (Source: International Ophthalmology)
Source: International Ophthalmology - March 27, 2018 Category: Opthalmology Source Type: research

Epibulbar osseous choristoma: a photo essay case report
ConclusionsEpibulbar osseous choristoma is a rare and benign condition which can present with features similar to dermolipoma. (Source: International Ophthalmology)
Source: International Ophthalmology - March 27, 2018 Category: Opthalmology Source Type: research

Orbital apex syndrome secondary to optic nerve cysticercosis
AbstractA 22-year-old male presented to us with complaints of sudden painful loss of vision in left eye 10  days ago along with inward deviation of the left eye. Best-corrected visual acuity (BCVA) in right eye was 20/20 and 20/50 in left eye. Left eye showed limitation of abduction, a relative afferent pupillary defect, normal anterior segment with optic disc oedema. Contrast-enhanced MRI of the brain and orbit showed thickening of left optic nerve along with a cystic lesion near the orbital apex with a central iso- to hyperintense spot resembling a scolex. A diagnosis of left orbital apex syndrome secondary to optic...
Source: International Ophthalmology - March 26, 2018 Category: Opthalmology Source Type: research

Strabismus surgery for diplopia in chronic progressive external ophthalmoplegia
ConclusionBilateral selective impairment of adduction and intermittent exotropia may be the presenting ocular motility disturbance in chronic progressive external ophthalmoplegia. Properly designed strabismus surgery may provide sustainable, in the midterm, control of alignment and symptomatic relief in selected patients with CPEO. (Source: International Ophthalmology)
Source: International Ophthalmology - March 26, 2018 Category: Opthalmology Source Type: research

Measurement of extraocular horizontal muscle insertion distance via anterior segment optical coherence tomography of healthy children and comparison with healthy adults
ConclusionsIn healthy individuals, different imaging modalities can be used to measure LID, but AS-OCT can be used in pediatric age-groups as a preferred imaging method because it is easy and noninvasive. (Source: International Ophthalmology)
Source: International Ophthalmology - March 26, 2018 Category: Opthalmology Source Type: research

Corneal densitometry after accelerated corneal collagen cross-linking in progressive keratoconus
ConclusionAccelerated CXL results in an increase in corneal densitometry, particularly in the anterior stromal layer within the two central concentric zones (0.0 to 2.0  mm and 2.0 to 6.0 mm) of the cornea at 3 months postoperatively. The changes in corneal densitometry of the anterior stromal layer did not correlate with postoperative visual acuity or central pachymetry. (Source: International Ophthalmology)
Source: International Ophthalmology - March 26, 2018 Category: Opthalmology Source Type: research

Elevated lipocalin-2 level in aqueous humor of patients with central retinal vein occlusion
ConclusionsConcentrations of LCN2 in aqueous humor are increased in CRVO. LCN2 may be part of a pro-catabolic phenotype, and it may play an important role in the dreaded complications of CRVO, such as macular edema, macular ischemia, and neovascularization, which lead to blindness. (Source: International Ophthalmology)
Source: International Ophthalmology - March 23, 2018 Category: Opthalmology Source Type: research

Reversal of retinal pigment epithelial detachment after cessation of topical travoprost therapy
ConclusionHence, clinicians should be aware of this rare incidence of RPED followed by travoprost therapy. First case of RPED following travoprost therapy and complete reattachment upon withdrawal is reported here in this case report. (Source: International Ophthalmology)
Source: International Ophthalmology - March 22, 2018 Category: Opthalmology Source Type: research

Could corneal densitometry be used as a diagnostic and screening tool for ocular involvement in patients with gout?
ConclusionsCorneal densitometry values of the 0 –2 and 2–6 mm zones of the anterior and central layers were higher in patients with gout than those of the control subjects, and the densitometric values increased as uric acid level and disease duration increased. (Source: International Ophthalmology)
Source: International Ophthalmology - March 21, 2018 Category: Opthalmology Source Type: research

Prospective, randomized contralateral eye study of accelerated and conventional corneal cross-linking in pediatric keratoconus
AbstractPurposeTo compare the outcomes of two different cross-linking (CXL) protocols, in pediatric keratoconus eyes.Materials and methodsIn this prospective randomized contralateral eye interventional study, 68 eyes of 34 patients, 9 –16 years old, underwent CXL and enrolled between October 2011 and October 2013. Group A represents conventional riboflavin–ultraviolet A (UVA)-induced CXL with 30 min of exposure to UVA irradiation of 3 mW/cm2. Group B represents accelerated cross-linking with 5  min of continuous UVA irradiation of 18 mW/cm2. In either group, total energy delivered was a...
Source: International Ophthalmology - March 21, 2018 Category: Opthalmology Source Type: research