Effect of filtering bleb dimensions on postoperative intraocular pressure in deep sclerectomy with collagen implant: a comparative study
ConclusionUsing collagen implant in DS significantly increases conjunctival bleb dimensions, which reflects on lower postoperative IOP. (Source: International Ophthalmology)
Source: International Ophthalmology - July 18, 2019 Category: Opthalmology Source Type: research

A comparison of Icare PRO and Perkins tonometers in anesthetized children
AbstractAimTo compare intraocular pressure (IOP) measurements obtained with the Perkins applanation tonometer and Icare PRO (ICP) rebound tonometer in anesthetized aphakic or strabismus children. Furthermore, intra-operator correlation and inter-operator correlation have been evaluated, along with the effects of central corneal thickness (CCT) on IOP measurements.MethodsSeventy children undergoing examination under anesthesia with sevoflurane for aphakic patients and for surgery for strabismus were included. IOP have been measured twice immediately after anesthesia induction with both Perkins applanation tonometer (PAT) an...
Source: International Ophthalmology - July 16, 2019 Category: Opthalmology Source Type: research

The value of nutritional supplements in treating Age-Related Macular Degeneration: a review of the literature
ConclusionThe data regarding nutritional supplements in preventing AMD progression are inconclusive, and therefore recommendations should be based on risk factors and demographic data. (Source: International Ophthalmology)
Source: International Ophthalmology - July 16, 2019 Category: Opthalmology Source Type: research

Assessment of tear meniscus by optical coherence tomography in patients with canalicular laceration repair
AbstractPurposeTo analyze tear meniscus measurements with optical coherence tomography (OCT) in patients with canalicular laceration repair.MethodsThirty-four consecutive patients who underwent unilateral canalicular repair due to canalicular laceration between January 2014 and December 2018 were included. All patients had canalicular repair followed by monocanalicular or annular silicone tube intubation. Anatomic patency of canalicular system was tested with probing and irrigation, while functional patency was evaluated with Munk score. Tear meniscus measurements of all patients were obtained following tube removal by spe...
Source: International Ophthalmology - July 15, 2019 Category: Opthalmology Source Type: research

Appearance of herpes simplex keratitis on anterior segment optical coherence tomography
ConclusionHerpetic keratouveitis has characteristic features on AS-OCT images. This study demonstrates that herpetic keratitis also has characteristic AS-OCT features, including sub-epithelial infiltration and specific stromal hyper-reflective patterns. These features are not unique to herpetic keratitis, but AS-OCT imaging may provide useful supplementary information for diagnosing and monitoring herpetic keratitis. (Source: International Ophthalmology)
Source: International Ophthalmology - July 15, 2019 Category: Opthalmology Source Type: research

Six-month results of suprachoroidal adipose tissue-derived mesenchymal stem cell implantation in patients with optic atrophy: a phase 1/2 study
ConclusionEven though the sample size is small, the improvements were still encouraging. Stem cell treatment with suprachoroidal implantation of ADMSCs seems to be safe and effective in the treatment for optic nerve diseases that currently have no curative treatment options. (Source: International Ophthalmology)
Source: International Ophthalmology - July 15, 2019 Category: Opthalmology Source Type: research

Combined retro-peribulbar and subconjunctival anesthesia for evisceration surgery
AbstractPurposeTo evaluate the efficacy of retro-peribulbar and subconjunctival anesthesia associated with intravenous sedation in patients undergoing evisceration and orbital implant placement.MethodsThe charts of 217 patients who underwent evisceration with trans-scleral implant placement were reviewed. Midazolam and fentanyl were used for intravenous sedation. For local anesthesia, a combination of lidocaine with epinephrine and bupivacaine was injected into the retrobulbar, upper peribulbar, and subconjunctival areas. The intraoperative pain and need for supplemental anesthetic injection were recorded prospectively.Res...
Source: International Ophthalmology - July 13, 2019 Category: Opthalmology Source Type: research

Intrachoroidal cavitation in myopic eyes
ConclusionICC is seen in 55.8% of highly myopic eyes with the presence of focal CRA or myopic conus and/or presence of intrascleral vessels near the cavitation. These findings suggest that patchy atrophy affects the scleral contour within posterior staphyloma beyond the funduscopically identified patchy atrophy by ICC. The presence of intrascleral vessels could also contribute to the ICC development. Eyes with patchy CRA or myopic conus needs to be checked on further follow-up visits for the development of macular or peripapillary ICC. (Source: International Ophthalmology)
Source: International Ophthalmology - July 12, 2019 Category: Opthalmology Source Type: research

Investigating the effects of glaucomatous damage on the multifocal visual evoked potential parameters
AbstractPurposeTo investigate the effects of glaucomatous damage on the mfVEP parameters of patients suffering from primary open-angle glaucoma (POAG).MethodsFifteen healthy subjects and 15 patients with unilateral POAG participated in this study. In addition, routine ophthalmological examinations including visual acuity, anterior segment examination, posterior segment examination, intraocular pressure, mfVEP with electrophysiological system, RETI-port/Scan 21, and visual field test with automated Humphrey ZEISS HFA II 750i Perimeter were also performed.ResultsThe results show that there was a strong correlation between th...
Source: International Ophthalmology - June 21, 2019 Category: Opthalmology Source Type: research

The efficacy of standard versus accelerated epi-off corneal cross-linking protocols: a systematic review and sub-group analysis
ConclusionsIn other words, efficacy is comparable among different CXL protocols, so it is recommended to use the standard method in cases where maximum flattening is expected, such as young people and severe cases. (Source: International Ophthalmology)
Source: International Ophthalmology - June 20, 2019 Category: Opthalmology Source Type: research

Therapeutic penetrating keratoplasty for acanthamoeba keratitis: a review of cases, complications and predictive factors
ConclusionTPK is a procedure with significant postoperative complications but is required by some patients with AK. Eyes with higher risk for needing TPK can be identified earlier and thus provided more intensive treatment and closer follow-up care. (Source: International Ophthalmology)
Source: International Ophthalmology - June 18, 2019 Category: Opthalmology Source Type: research

Role of in vivo confocal microscopy in the diagnosis of infectious keratitis
ConclusionIVCM is an non-invasive imaging modality that can rapidly and accurately diagnose IK even for experienced corneal specialists. In complex cases of polymicrobial infection, IVCM may guide the correct clinical diagnosis and initiation of the appropriate treatment. (Source: International Ophthalmology)
Source: International Ophthalmology - June 17, 2019 Category: Opthalmology Source Type: research

Correction to: Pigment dispersion syndrome and pigmentary glaucoma: a review and update
In the original publication, introduction section under Abstract was published incorrectly. The correct version is given below. (Source: International Ophthalmology)
Source: International Ophthalmology - June 6, 2019 Category: Opthalmology Source Type: research

Presbyopic lens exchange (PRELEX) cataract surgery outcomes with implantation of a rotationally asymmetric refractive multifocal intraocular lens: femtosecond laser-assisted versus manual phacoemulsification
AbstractPurposeTo compare the visual and refractive outcomes obtained with the implantation of a rotationally asymmetric refractive multifocal IOL after femtosecond laser-assisted cataract surgery (FLACS) and conventional lens extraction (CLE).MethodsA total of 78 eyes of 58 patients that had undergone conventional phacoemulsification (36 eyes, CLE group) or FLACS (37 eyes, FLACS group) with the implantation of the toric multifocal IOL LU-313 MF30T (Oculentis, Germany) were enrolled in this retrospective study. Mean age was 57.0  years at the time of surgery, ranging from 44 to 69 years. Visual and refractive out...
Source: International Ophthalmology - June 5, 2019 Category: Opthalmology Source Type: research

Higher expression of cation transport regulator-like protein 1 (CHAC1) predicts of poor outcomes in uveal melanoma (UM) patients
ConclusionsOur results suggested that CHAC1 functioned as a facilitator in UM cell proliferation and migration and possessed the potential to be a predictor as well as a therapeutic target for UM patients. (Source: International Ophthalmology)
Source: International Ophthalmology - June 3, 2019 Category: Opthalmology Source Type: research

Clinical diversity in macular corneal dystrophy: an optical coherence tomography study
ConclusionsMCD exhibits a clinically diverse presentation as revealed on the clinical and optical coherence tomography study. Immunophenotype and genotype –phenotype correlation may further help in understanding various clinical presentations of MCD. (Source: International Ophthalmology)
Source: International Ophthalmology - June 3, 2019 Category: Opthalmology Source Type: research

Association of Ramadan daytime fasting with ocular surface inflammation and dry eye
ConclusionRamadan fasting has a significant impact on TBUT and ocular surface inflammation detected by Inflamma Dry testing. Patients who suffer from dry eye disease and those who develop symptoms during Ramadan are advised to consult with a physician before or during Ramadan fasting. (Source: International Ophthalmology)
Source: International Ophthalmology - May 31, 2019 Category: Opthalmology Source Type: research

Deep topical anesthesia with ropivacaine-soaked sponge for phacoemulsification
ConclusionsDeep topical anesthesia with ropivacaine-soaked sponges performed as well as topical oxybuprocaine regarding safety and efficacy. It provided a lower patient pain score, favorable surgeon satisfaction, and long-lasting anesthesia. (Source: International Ophthalmology)
Source: International Ophthalmology - May 31, 2019 Category: Opthalmology Source Type: research

Vision-related quality of life after pars plana vitrectomy with or without combined cataract surgery for idiopathic macular hole patients
AbstractPurposeTo evaluate the influence of vision-related quality of life (VR-QOL) after pars plana vitrectomy (PPV) with or without combined cataract surgery for idiopathic macular hole (IMH) patients.MethodsThis prospective consecutive case series study included 53 eyes of 53 consecutive IMH patients who were divided into two groups: 34 eyes underwent PPV combined with cataract surgery (combined group), 19 eyes only underwent PPV (vitrectomy group). Clinical data were collected at baseline and 3 and 6  months after surgery, respectively, including VR-QOL evaluated by The National Eye Institute 25-Item Visual Functi...
Source: International Ophthalmology - May 29, 2019 Category: Opthalmology Source Type: research

Probucol promotes high glucose-induced proliferation and inhibits apoptosis by reducing reactive oxygen species generation in M üller cells
AbstractPurposeTo explore the protective effect of probucol on human retinal M üller cells cultured in high glucose.MethodsPrimary M üller cells from human retinas were cultured in complete DMEM. Third-generation Müller cells were identified using glutamine synthetase (GS) antibody and randomly divided into three groups: normoglycemia (NG, 5.5 mmol/L); hyperglycemia (HG, 30 mmol/L); and hyperglycemia (30 mmol/L) with probuco l (10 μmol/L; HGPB). After a 24-h intervention, cell proliferation, apoptosis, and cellular reactive oxygen species (ROS) were measured with a CCK-8 kit, flow cyto...
Source: International Ophthalmology - May 29, 2019 Category: Opthalmology Source Type: research

Perfluoro- n -octane-assisted autologous internal limiting membrane plug for refractory macular hole surgery
ConclusionsThis surgical technique using PFO-assisted autologous ILM plug may provide an option for the treatment of refractory MH. (Source: International Ophthalmology)
Source: International Ophthalmology - May 28, 2019 Category: Opthalmology Source Type: research

Effect of intracameral human cord blood-derived stem cells on lasered rabbit trabecular meshwork
ConclusionsThere was a relative preservation of cellularity and architecture of the trabecular meshwork in eyes injected with human cord blood stem cells, as compared to lasered control eyes up to 12  weeks, without significant inflammation. This suggests a probable role for such stem cells in eyes with glaucoma, having trabecular dysfunction. (Source: International Ophthalmology)
Source: International Ophthalmology - May 28, 2019 Category: Opthalmology Source Type: research

Choroidal binarization analysis: clinical application
ConclusionBinarization of choroidal images seems to represent a promising approach to study choroid subcomponents in an increasingly detailed manner. (Source: International Ophthalmology)
Source: International Ophthalmology - May 28, 2019 Category: Opthalmology Source Type: research

Evaluation of biometry and corneal astigmatism in cataract surgery patients in Northern United Arab Emirates
ConclusionsResults of this study provide normative data for cataract surgery as an informative reference in Northern UAE, the Middle East. This study showed higher corneal astigmatism in Northern UAE than those in other countries. (Source: International Ophthalmology)
Source: International Ophthalmology - May 27, 2019 Category: Opthalmology Source Type: research

Corneal power measurement with a new aberrometer/corneal topographer in eyes after small incision lenticule extraction for myopia
ConclusionsThe ECCP provided with OPD SCAN III could be used as an alternative option for the CHM after specific modifications in eyes with previous myopic SMILE surgery when the preoperative data are unavailable considering the narrowest agreement between the modified ECCP and the CHM. Otherwise, caution must be raised considering the wide LOA. (Source: International Ophthalmology)
Source: International Ophthalmology - May 27, 2019 Category: Opthalmology Source Type: research

Clinical features of anterior uveitis caused by three different herpes viruses
ConclusionClinical findings of HSV-AU and VZV-AU were similar; however, more inflammatory findings were observed in VZV-AU. Iris atrophy morphologically differed in HSV-AU and VZV-AU. Inflammatory findings in CMV-AU were mild, and clinical features of iritis differed from those of the two former groups. A difference in the etiology between CMV-AU and P –S syndrome was observed. (Source: International Ophthalmology)
Source: International Ophthalmology - May 27, 2019 Category: Opthalmology Source Type: research

Corneal biomechanical changes after trabeculectomy with mitomycin C in primary open-angle glaucoma and pseudoexfoliation glaucoma
This study aimed to examine the effect of trabeculectomy with mitomycin C on corneal biomechanical characteristics in PEXG and POAG patients.MethodsIn this prospective comparative case series study, 32 glaucoma patients of whom 17 patients were suffering from PEXG and 15 patients from POAG were enrolled. All patients underwent complete ocular examination, CCT using ultrasound pachymetry and corneal biomechanical study using ORA. The patients were hospitalized, and trabeculectomy surgery with mitomycin was done. Three months after surgery, patients were examined and ORA was obtained again.ResultsThe mean CH in patients with...
Source: International Ophthalmology - May 27, 2019 Category: Opthalmology Source Type: research

Reduced vascular perfusion density in idiopathic epiretinal membrane compared to macular pseudohole
AbstractPurposeTo investigate the retinal capillary perfusion density by means of optical coherence tomography angiography (OCT-A) in idiopathic epiretinal membrane (ERM) and macular pseudoholes (MPH).MethodsThis observational cross-sectional study examined consecutive patients affected by ERM and MPH presenting between June 2017 and December 2017, as well as the 30 eyes of 30 healthy subjects. All patients underwent swept-source OCT-A examination. For each patient, vessel perfusion density and foveal avascular zone (FAZ) area were measured.ResultsTwenty-five eyes of 20 patients with ERM and 28 eyes of 24 patients with MPH...
Source: International Ophthalmology - May 27, 2019 Category: Opthalmology Source Type: research

Ocular manifestations in patients with cerebrovascular accidents in India: a cross-sectional observational study
ConclusionsOphthalmic manifestations were seen in 90% of stroke survivors. Their presence in majority of the patients in our cohort suggests that earliest routine ophthalmic examination should be mandatory in all patients with acute stroke. (Source: International Ophthalmology)
Source: International Ophthalmology - May 25, 2019 Category: Opthalmology Source Type: research

Results of pars plana vitrectomy for primary rhegmatogenous retinal detachment with PVR grades A and B in high-myopic eyes
ConclusionThe anatomical success of primary PPV for RRD did not differ between high-myopic and non-high-myopic eyes in PVR grades A and B. However, functional results of high-myopic eyes are worse compared to eyes without high axial myopia. (Source: International Ophthalmology)
Source: International Ophthalmology - May 25, 2019 Category: Opthalmology Source Type: research

Optical coherence tomography angiography analysis of macular vessel density before and after anti-VEGF therapy in eyes with diabetic retinopathy
ConclusionsIn this study, macular vessel density remained statistically unchanged following up to three intravitreal injections of any anti-VEGF agent. This indicates that there may not be an early effect of anti-VEGF treatment on macular vessel density and its effect on macular perfusion may not be a direct change in microvascular flow. (Source: International Ophthalmology)
Source: International Ophthalmology - May 22, 2019 Category: Opthalmology Source Type: research

Local allergic conjunctivitis: a phenotype of allergic conjunctivitis
ConclusionsThese results suggest the existence of LAC that is a candidate of a phenotype of AC. (Source: International Ophthalmology)
Source: International Ophthalmology - May 15, 2019 Category: Opthalmology Source Type: research

Small-incision lenticule addition in ex vivo model of ectatic human corneas
AbstractPurposeTo investigate the feasibility of intrastromal lenticule insertion to restore corneal shape in a model of ectatic human cornea.MethodsFor this experimental ex vivo study on 34 human corneas unsuitable for transplantation, 17 corneas were thinned by decentralized posterior excimer laser ablation to 200  μm thickness and 6.5 mm diameter and then inflated up to 100 mm Hg to expose the ectasias (recipient corneas). Pachimetry and topography were obtained. Stromal lenticules of the same diameter and thickness as the ectasias were shaped with a femtosecond laser from the remaining 17 donor cornea...
Source: International Ophthalmology - May 13, 2019 Category: Opthalmology Source Type: research

Ocular inflammation associated with relapsing polychondritis in Japanese patients: a review of 11 patients
ConclusionsOcular inflammation is often bilateral and recurring. Patients with ocular inflammation must be questioned regarding systemic symptoms so that the signs of relapsing polychondritis are not overlooked. Early diagnosis and prompt, appropriate treatment are important because relapsing polychondritis is a potentially lethal disease. (Source: International Ophthalmology)
Source: International Ophthalmology - May 10, 2019 Category: Opthalmology Source Type: research

Swept source-OCT and swept source-OCT angiography findings in posterior microphthalmos
AbstractPurposeTo describe swept source-OCT (SS-OCT) and swept source-OCT angiography (SS-OCTA) findings in eyes with posterior microphthalmos (PM).MethodsTwelve eyes (six patients) with PM were evaluated using SS-OCT and SS-OCTA. Structural changes, subfoveal choroidal thickness (SFCT), and perifoveal capillary changes with qualitative and quantitative assessments were analyzed. Twenty eyes served as control group.ResultsSS-OCT findings included elevated retinal papillo-macular fold (75%), retinal pigment epithelium folds (83%), macular cystoid spaces (42%), subretinal fluid (17%), and increased visibility of posterior vi...
Source: International Ophthalmology - May 10, 2019 Category: Opthalmology Source Type: research

Association of KIF26B and COL4A4 gene polymorphisms with the risk of keratoconus in a sample of Iranian population
ConclusionOur results did prove a statistical association of both rs2228557 and rs12407427 genotypes (TT and CT  + CC) and allele (T) with KTCN susceptibility in Iranian population. Further studies in other ethnicities are required to verify our results. (Source: International Ophthalmology)
Source: International Ophthalmology - May 10, 2019 Category: Opthalmology Source Type: research

Retinal perfusion 6  months after trabeculectomy as measured by optical coherence tomography angiography
AbstractPurposeTo investigate potential changes of vessel density (VD) at the optic nerve head (ONH) and the macula 6  months after trabeculectomy (TE).MethodsIn a prospective monocentric study, 19 eyes with open-angle glaucoma were treated with TE  + MMC (mitomycin C). At four different time points multiple morphological papillary parameters were measured by OCT, and the ONH VD in the radial peripapillary capillary layer and the superficial and deep plexuses of the macula was determined by OCTA (optical coherence tomography angiography, R TVue-XR, Optovue). The mean defect was determined by visual field...
Source: International Ophthalmology - May 9, 2019 Category: Opthalmology Source Type: research

Long-term changes in retinal layers in patients undergoing intravitreal ranibizumab for neovascular age-related macular degeneration
ConclusionsSignificant changes were observed in the thickness of the inner RLs after 1-year treatment with IVRs for n-AMD. A significant decrease in RPE thickness confined to the first months disappeared at month-12. (Source: International Ophthalmology)
Source: International Ophthalmology - May 8, 2019 Category: Opthalmology Source Type: research

Diabetes mellitus is associated with dry eye syndrome: a meta-analysis
AbstractBackgroundDry eye is the most common eye disorder of tears and ocular surface. However, the extent to which diabetes mellitus may confer risk of dry eye remains uncertain. The aim of this study was to perform a meta-analysis that synthesizes the association between diabetes mellitus and dry eye.MethodsCase –control studies were selected from the Medline, Embase, Cochrane database from January 2000 to March 2018. Two reviewers screened potential studies, and eligible studies were included according to keywords and predefined criteria. We calculated the overall risk estimates by using a fixed-effect m odel or a...
Source: International Ophthalmology - May 7, 2019 Category: Opthalmology Source Type: research

Choroidal thickness in macular holes
AbstractPurposeTo determine the association between choroidal thickness (CT) and anatomic success in closed and open macular holes (MHs) following surgery.MethodsOne hundred and thirty-six eyes of 136 patients who underwent surgery due to primary MH were included in this study. Choroidal thickness was measured from various points (subfoveal, temporal, nasal, superior and inferior 1500  µm from the center of the fovea) in both eyes with MH and fellow eyes. We determined associations among the duration of symptoms, MH dimensions and CTs from various points with anatomic success and correlations between CT and MH d...
Source: International Ophthalmology - May 7, 2019 Category: Opthalmology Source Type: research

Comparison of Samfilcon A and Lotrafilcon B silicone hydrogel bandage contact lenses in reducing postoperative pain and accelerating re-epithelialization after photorefractive keratectomy
In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit biomicroscopy was performed to assess epithelial defect size in the postoperative examinations. The subjective evaluation of pain and visual symptoms was recorded on postoperative days 1, 2 and 3.ResultsAnalysis was made of 68 eyes of 34 patients who fulfilled the criteria and had PRK for correction of low to moderate myopia/astigmatism. On postoperative days 1 and 2, pain and epiphora scores were significantly lower ...
Source: International Ophthalmology - May 7, 2019 Category: Opthalmology Source Type: research

Aqueous humor IL-8, IL-10, and VEGF levels in Fuchs ’ uveitis syndrome and Behçet’s uveitis
This study investigated the levels of interleukin (IL)-8, IL-10, and vascular endothelial growth factor (VEGF) in the aqueous humor (AqH) of patients with Beh çet’s uveitis (BU) and Fuchs’ uveitis syndrome (FUS) during an inactive period and compared these levels with those in the AqH of noninflammatory healthy control subjects.MethodsThis prospective and case –control study included 33 patients (16 patients with BU and 17 patients with FUS) and 35 control subjects. IL-8, IL-10, and VEGF levels in the AqH were quantified by performing sandwich enzyme-linked immunosorbent assay. Kruskal–Wallis...
Source: International Ophthalmology - May 7, 2019 Category: Opthalmology Source Type: research

Geometrical characterization of the corneo-scleral transition in normal patients with Fourier domain optical coherence tomography
ConclusionsThe CSAn presents a more concave profile for the normal population, whereas the CSAt presents a planar-convex profile with a great influence of age. In particular, the older the patient, the more convex the CSAt is. This age-related evolution of the CSAt and the concavity on the nasal direction must be considered when prescribing scleral contact lenses or when performing limbal incisions during refractive interventions. (Source: International Ophthalmology)
Source: International Ophthalmology - May 7, 2019 Category: Opthalmology Source Type: research

Genetic polymorphisms associated with the prevalence of retinal vein occlusion in a Greek population
ConclusionsAGTR1 A1166C andGpla/lla C807T/G873A polymorphisms are likely to be risk factors for CRVO.Adiponectin + 276 G/T SNP is likely to predispose to RVO in older subjects. (Source: International Ophthalmology)
Source: International Ophthalmology - May 7, 2019 Category: Opthalmology Source Type: research

Very late-onset flap margin corneal ulcer following laser in situ keratomileusis
ConclusionsLASIK may be associated with an increased risk of late-onset corneal ulcer occurring years after the procedure. Instability of the flap margin, blepharitis and dry eye are possible causes of epithelial disturbance and may account for this complication. (Source: International Ophthalmology)
Source: International Ophthalmology - April 13, 2019 Category: Opthalmology Source Type: research

Multimodal imaging including optical coherence tomography angiography in patients with type B Niemann –Pick disease
ConclusionMultimodal imaging including OCTA is a useful technique for the identification of different types of accumulation patterns, diagnosis and follow-up of type B Niemann –Pick patients. (Source: International Ophthalmology)
Source: International Ophthalmology - April 11, 2019 Category: Opthalmology Source Type: research

Lensectomy after radial keratotomy: 1-year follow-up
ConclusionsPseudophakic monofocal IOL implantation offers good visual acuity recovery and acceptable refractive correction in RK patients after 1-year follow-up. (Source: International Ophthalmology)
Source: International Ophthalmology - April 11, 2019 Category: Opthalmology Source Type: research

Rhodopsin gene mutation analysis in Iranian patients with autosomal dominant retinitis pigmentosa
ConclusionsOur study showed that mutations of the rhodopsin gene are relatively frequent in Iranian patients with ADRP and could be considered in further researches in the future. The novel p.L95P variant may be associated with a specific pattern of retinal degeneration in this population. (Source: International Ophthalmology)
Source: International Ophthalmology - April 10, 2019 Category: Opthalmology Source Type: research

Configuration of recipient corneal cut after mechanical trephination in keratoconus
This study enrolled 85 eyes with keratoconus that underwent DALK. Recipient corneas were partially trephined using a new, unused, disposable Hessburg-Barron suction trephine. Photographs that best represented the recipient corneal cut were selected, and ImageJ software was used to evaluate the roundness of recipient bed. The effect of potential variables on the roundness of cuts was investigated using the univariate analyses.ResultsThe mean patient age was 31.0  ± 9.0 years. The mean recipient trephine size was 8.04 ± 0.29 mm (range 7.5–8.50 mm). The recipient ...
Source: International Ophthalmology - April 9, 2019 Category: Opthalmology Source Type: research

Intraocular pressure measurement with Corvis ST in comparison with applanation tonometry and Tomey non-contact tonometry
AbstractPurposeIntraocular pressure (IOP) measurement can be performed with different methods. Newer methods have to be compared to the standard method, the Goldmann applanation tonometry (GAT). We herein compare two air-puff tonometers, the non-contact tonometer (Tomey NCT) and the Corvis ST (CST) with GAT in eyes with a broad spectrum of IOP.MethodsTwo hundred and forty-nine eyes of 249 patients (with diagnosis of either glaucoma or ocular hypertension) were included in this monocenter prospective cohort study. Each eye underwent IOP measurements via GAT, NCT and CST. Bland –Altman plots were calculated to compare ...
Source: International Ophthalmology - April 9, 2019 Category: Opthalmology Source Type: research