Optical coherence tomography angiography analysis of fabry disease
ConclusionDecreased VD and an enlarged foveal avascular area suggest possible changes in the retinal microvasculature of patients with FD. OCT-A can serve as a  useful, noninvasive, quantitative tool for diagnosing FD and monitoring its progression. (Source: International Ophthalmology)
Source: International Ophthalmology - October 13, 2020 Category: Opthalmology Source Type: research

Quantitative and objective diagnosis of color vision deficiencies based on steady-state visual evoked potentials
AbstractPurposeTraditional color vision tests depend on subjective judgments and are not suitable for infant children and subjects with cognitive dysfunction. We aimed to explore an objective and quantitative color vision testing method based on sweep steady-state visual evoked potentials (sweep SSVEPs) and compare the results with subjective Farnsworth –Munsell (FM) 100-hue test results.MethodsA red-green SSVEP pattern reversal checkboard paradigm at different luminance ratios was used to induce visual evoked potentials (VEPs) from 15 color vision deficiencies (CVDs) and 11 normal color vision subjects. After electr...
Source: International Ophthalmology - October 12, 2020 Category: Opthalmology Source Type: research

Clinical application of ultra-widefield fundus autofluorescence
ConclusionUWF-FAF can detect abnormalities that traditional fundus autofluorescence cannot; therefore, it can be used to better elucidate disease pathogenesis, analyze genotype –phenotype correlations, diagnose and monitor disease. (Source: International Ophthalmology)
Source: International Ophthalmology - October 11, 2020 Category: Opthalmology Source Type: research

Comparison between bilateral implantation of a trifocal intraocular lens (Alcon Acrysof IQ ® PanOptix) and extended depth of focus lens (Tecnis® Symfony® ZXR00 lens)
ConclusionBoth strategies were able to provide good vision for far, intermediate and near distances. (Source: International Ophthalmology)
Source: International Ophthalmology - October 10, 2020 Category: Opthalmology Source Type: research

Persistent subretinal fluid following diabetic tractional retinal detachment repair: risk factors, natural history, and management outcomes
AbstractPurposeTo study the natural history, anatomical and functional outcomes of persistent subretinal fluid (SRF) after pars plana vitrectomy (PPV) for diabetic tractional retinal detachment (TRD) and combined traction-rhegmatogenous retinal detachment (TRRD).MethodsRetrospective interventional case series of 43 patients (46 eyes) with persistent SRF following PPV for diabetic TRD or combined TRRD from January 2010 to December 2017 at single tertiary institution. Primary outcomes included best corrected visual acuity (BCVA) and central foveal thickness (CFT).ResultsThirty-one eyes (67.4%) had macula-off TRD, 5 (10.9%) h...
Source: International Ophthalmology - October 9, 2020 Category: Opthalmology Source Type: research

Vision function of pseudophakic eyes with posterior capsular opacification under different speed and spatial frequency
AbstractPurposeTo investigate the characteristics of dynamic visual acuity (DVA) and contrast sensitivity (CS) in pseudophakic patients with posterior capsular opacification (PCO).MethodsFifty-four eyes (36 patients) with PCO planned for laser capsulotomy were recruited. They underwent examinations of static visual acuity (SVA), DVA, CS and optical quality analysis (OQAS) before and one week after the laser treatment. Improvements in each index after laser treatment were analyzed. The visual quality of patients with good initial vision was studied separately.ResultsSVA, DVA and CS all significantly increased after capsulotomy (P 
Source: International Ophthalmology - October 8, 2020 Category: Opthalmology Source Type: research

The effects of epiretinal membranes on the treatment outcomes of intravitreal aflibercept injection in diabetic macular edema: a real-life study
AbstractPurposeTo evaluate the effects of epiretinal membrane (ERM) formation on the anatomic and functional results of subjects with diabetic macular edema (DME) who are receiving intravitreal aflibercept injections (IAIs).Materials and methodsThis retrospective comparative study includes 29 eyes with DME (Group 1) and 43 eyes with DME and ERM (Group 2). After three consecutive monthly 2.0  mg IAIs, subjects received monthly follow-ups and retreatment was performed if needed. Corrected visual acuity (CVA), central macular thickness (CMT), and central macular volume (CMV) parameters were recorded tri-monthly, and the ...
Source: International Ophthalmology - September 20, 2020 Category: Opthalmology Source Type: research

Xen implantation in patients with primary open-angle glaucoma: comparison of two different techniques
AbstractPurposeTo compare retrospectively two different techniques of Xen implantation, which are transconjunctival (ab-externo) and standard (ab-interno) techniques.MethodsForty-three eyes of 43 patients with primary open-angle glaucoma (POAG) who had Xen implantation operation via transconjunctival (ab-externo) technique comprised Group 1. Of the 43 patients, 20 (46.5%) were males and 23 (53.5%) were females. Their mean age was 61.76  ± 8.81 (41–74) years. Forty-four eyes of 44 patients with POAG who had Xen implantation operation via standard (ab-interno) technique comprised Group 2. Of the 44...
Source: International Ophthalmology - September 20, 2020 Category: Opthalmology Source Type: research

Keratoconus: a potential risk factor for osteoarthritis
This study was undertaken to compare the distal femoral cartilage thickness in patients with keratoconus (KC) with that of age- and sex-matched healthy controls, in order to identify a potential risk factor for early osteoarthritis in patients with KC and to allow initiation of early rehabilitation.MethodsThirty-six KC patients between 18 and 35 years of age and 36 healthy controls were included in this study. Keratometry readings (K1,K2), central corneal thickness (CCT), anterior chamber depth (ACD), iridocorneal angle (ICA), and corneal volumes (CV) were measured using a Sirius imaging system (Costruzioni Strumenti Oftal...
Source: International Ophthalmology - September 20, 2020 Category: Opthalmology Source Type: research

Agreement in central corneal thickness measurement between Corvis ST and ocular response analyzer
AbstractPurposeTo evaluate the agreement and interchangeability of noncontact devices of ocular response analyzer (ORA) and the Corvis ST in central corneal thickness measurement.MethodsIn this prospective comparative study, central corneal thickness (CCT) readings of 284 healthy, nonglaucoma subjects, without previous ocular surgery, were measured with ORA and Corvis ST. Only data from right eyes were analyzed. The mean values of CCT measurements by the ORA versus Corvis ST were compared with the paired samplet test. Bland –Altman plots and 95% limits of agreement (95% LOA) were used to assess the agreement between ...
Source: International Ophthalmology - September 20, 2020 Category: Opthalmology Source Type: research

Hydroxychloroquine and chloroquine retinal safety concerns during COVID-19 outbreak
ConclusionA possible future clinical perspective for patients with COVID-19 treated with HCQ/CQ could reside in the multidisciplinary collaboration between ophthalmologists monitoring the risk of HCQ/CQ-related retinal toxicity and those physicians treating COVID-19 infection. (Source: International Ophthalmology)
Source: International Ophthalmology - September 17, 2020 Category: Opthalmology Source Type: research

Optical coherence tomography indices for diagnosis of chronic glaucoma in patients with diabetes mellitus: a pilot study
AbstractPurposeTo evaluate optical coherence tomography (OCT) parameters in patients with concomitant type-2 diabetes mellitus (DM) and primary open angle glaucoma (POAG) compared with patients with either of these diseases.MethodsSixty eyes (52 patients) were divided into three groups. The first group included nonglaucomatous diabetic patients, the second included patients with POAG without DM, and the third included patients with both POAG and DM. Spectral domain OCT evaluation of the retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and optic disc parameters was performed. Visual field (VF) was measured for...
Source: International Ophthalmology - September 17, 2020 Category: Opthalmology Source Type: research

Excisional penetrating keratoplasty for fungal interface keratitis after endothelial keratoplasty: surgical timing and visual outcome
ConclusionTPK with removal of the sequestered infection is advocated as a safe and effective measure to treat a post-EK infection. Early surgery allows a reduced exposure time to infection and therefore may result in better visual outcomes and lower risk of complications caused by prolonged inflammation. (Source: International Ophthalmology)
Source: International Ophthalmology - September 16, 2020 Category: Opthalmology Source Type: research

Hemodynamics of the temporal and nasal short posterior ciliary arteries in pseudoexfoliation syndrome
ConclusionThere were significant decreases in temporal SPCA hemodynamic parameters in patients with pseudoexfoliation syndrome. These findings suggest that temporal SPCA ocular blood flow measurements have greater diagnostic value than those of the nasal SPCA. (Source: International Ophthalmology)
Source: International Ophthalmology - September 14, 2020 Category: Opthalmology Source Type: research

Ocular involvement in coronavirus disease 2019 (COVID-19): a clinical and molecular analysis
ConclusionsAmong patients admitted to a tertiary referral center with confirmed COVID-19, active conjunctival injection was noted in one out of five cases, and was associated with loss of smell and taste. Conjunctival swabs for viral RNA were negative in patients with and without ocular involvement. (Source: International Ophthalmology)
Source: International Ophthalmology - September 13, 2020 Category: Opthalmology Source Type: research

A novel splice site mutation in the SDCCAG8 gene in an Iranian family with Bardet –Biedl syndrome
ConclusionsThis study was conducted to show the aberrant alternative splicing as one of the single splicing mutations identified can cause BBS by affecting the function of SDCCAG8 protein. (Source: International Ophthalmology)
Source: International Ophthalmology - September 13, 2020 Category: Opthalmology Source Type: research

Evaluation of radial peripapillary capillary density in patients with newly diagnosed iron deficiency anemia
ConclusionIt is important to identify changes in retinal vascularity to prevent possible ocular problems in patients with IDA. Specifically, the significant positive correlations between RPCvd values and hematological values suggest that anemia treatment is important for optic nerve perfusion. (Source: International Ophthalmology)
Source: International Ophthalmology - September 12, 2020 Category: Opthalmology Source Type: research

The relationship between major intrinsic protein genes and cataract
ConclusionThese single-base mutations and single nucleotide polymorphisms might be importantly involved in the pathogenesis of congenital cataract and age-related cataract, respectively. This review provides a significant reference for clinical trials and theoretical studies. (Source: International Ophthalmology)
Source: International Ophthalmology - September 11, 2020 Category: Opthalmology Source Type: research

Explantation of phakic intraocular lenses: causes and outcomes
AbstractPurposeTo describe reasons for explantation of anterior and posterior chamber phakic intraocular lenses (pIOLs), as well as outcomes of the surgery.MethodsThe medical files of patients who underwent pIOL explantation due to complications were reviewed. All patients were divided into three groups based on the type of explanted pIOL: anterior chamber angle-supported (AS pIOL), anterior chamber iris-fixated (IF pIOL), and posterior chamber (PC pIOL).ResultsSixty-two eyes of 41 patients were evaluated. There were 26 (41.9%), 16 (25.8%), and 20 (32.2%) eyes in the AS pIOL, IF pIOL, and PC pIOL groups, respectively. The ...
Source: International Ophthalmology - September 10, 2020 Category: Opthalmology Source Type: research

Comparison of reading performance with low add bifocal and extended depth of focus intraocular lenses implanted with mini-monovision
ConclusionsWhen implanted with mini-monovision, although functional near visual acuity and a high degree of spectacle independence at near distances were achieved with both IOLs, patients implanted with the EDOF IOL preferred closer reading distance than those implanted with the low add diffractive multifocal IOL. (Source: International Ophthalmology)
Source: International Ophthalmology - September 10, 2020 Category: Opthalmology Source Type: research

Transepithelial phototherapeutic keratectomy for the treatment of severe band keratopathy
ConclusionsTransepithelial PTK is an effective treatment to eliminate corneal opacity and alleviate symptoms in patients with severe band keratopathy. This technique could be an alternative approach to managing severe band keratopathy. (Source: International Ophthalmology)
Source: International Ophthalmology - September 10, 2020 Category: Opthalmology Source Type: research

Full- versus partial-thickness sutures: experimental models of corneal injury repair
ConclusionsThe FT group presented less corneal edema at week 8 with a more linear and less opaque scar. Histopathology showed a better-organized scar and endothelialization without the formation of a fibrous membrane. (Source: International Ophthalmology)
Source: International Ophthalmology - September 10, 2020 Category: Opthalmology Source Type: research

Pars plana vitrectomy for posteriorly dislocated intraocular lenses: risk factors and surgical approach
ConclusionPosterior intraocular lens dislocation is becoming more prevalent. The main underlying causes found in this series were previous vitrectomy, myopia and recurrent intra-vitreal substance injections. Visual acuity improved in most cases after lens repositioning; however visual outcome is often limited due to associated ocular co-morbidities despite adequate lens position. Despite complete lack of zonular support, a posteriorly dislocated IOL can often be preserved by repositioning and fixation of the lens in the posterior chamber. Pathologies primarily associated with this type of lens malposition include history o...
Source: International Ophthalmology - September 10, 2020 Category: Opthalmology Source Type: research

Glaucoma patients have an increased level of trimethylamine, a toxic product of gut bacteria, in the aqueous humor: a pilot study
ConclusionTMA, but not TMAO or betaine level, is increased in the aqueous humor of patients with glaucoma. TMA might play a role in pathogenesis of glaucoma; however, prospective studies are needed to confirm our findings. (Source: International Ophthalmology)
Source: International Ophthalmology - September 10, 2020 Category: Opthalmology Source Type: research

Ocular surgery after herpes simplex and herpes zoster keratitis
ConclusionsWithin the article, we discuss the available evidence for HSK/HZO prophylaxis in ocular surgery. Additional studies would be required to define the real risk of HSK/HZO recurrence following eye surgeries, and particularly cataract surgery, and to confirm the utility of perioperative HSK/HZO prophylaxis. (Source: International Ophthalmology)
Source: International Ophthalmology - September 9, 2020 Category: Opthalmology Source Type: research

Correction of pseudophakic presbyopia using Lasik with aspheric ablation profiles and a micro-monovision protocol
This study included 50 pseudophakic eyes of 25 patients. Full ophthalmic examination, dominant eye tests and tests for tolerance of anisometropia (1 or 2  diopters) were done preoperatively. All cases were treated by Lasik with laser-blended vision technique. The dominant eye corrected to plano, and the nondominant eye corrected with near add in the range from 1.50 to 2.00 diopters. Excimer laser ablation was done using the MEL90 with a 250-Hz puls e rate (Carl Zeiss Meditec, Jena, Germany, Triple-A profile, Lasik mode). The follow-up period was 6 months with visits at 1, 3 and 6 months postoperatively....
Source: International Ophthalmology - September 8, 2020 Category: Opthalmology Source Type: research

Evaluating the effectiveness of localized sub-Tenon ’s anesthesia in 23-gauge vitreoretinal surgery
ConclusionLocalized sub-Tenon ’s anesthesia is as effective as retrobulbar anesthesia in many steps of vitreoretinal surgery for providing pain control. It can be considered an alternative form of local anesthesia. (Source: International Ophthalmology)
Source: International Ophthalmology - September 8, 2020 Category: Opthalmology Source Type: research

Comparison between aberration-free transepithelial photorefractive keratectomy and small incision lenticule extraction for correction of myopia and myopic astigmatism
AbstractPurposeTo evaluate the clinical outcomes of small incision lenticule extraction (SMILE) and aberration-free transepithelial photorefractive keratectomy (AF t-PRK) in patients with low to moderate  myopic astigmatism, including visual acuity, refractive outcomes, astigmatic vector analysis and corneal aberrometric changes.MethodThis retrospective comparative case series study involved 110 right eyes of 110 patients who underwent either SMILE (55 eyes) or AF t-PRK (55 eyes). Visual acuity, manifest refractive error and corneal higher-order aberrations (HOAs) were measured and analyzed at baseline, 1  month ...
Source: International Ophthalmology - September 7, 2020 Category: Opthalmology Source Type: research

Ocular microcirculation changes, measured with laser speckle flowgraphy and optical coherence tomography angiography, in branch retinal vein occlusion with macular edema treated by ranibizumab
This study searched for early predictive vascular biomarkers for visual outcomes in eyes with macular edema caused by branch retinal vein occlusion (BRVOME).MethodsTwenty-four eyes of 24 subjects with BRVOME were treated with the intravitreal injection of ranibizumab (IVR) for at least 6  months. We measured mean blur rate (MBR) in the optic nerve head (ONH) and vessel density (VD) in the macula with laser speckle flowgraphy and optical coherence tomography angiography, respectively.ResultsSix-month post-IVR best-corrected visual acuity (BCVA) was correlated positively with age, pre-IVR BCVA, 1-month post-IVR BCVA, 3-...
Source: International Ophthalmology - September 6, 2020 Category: Opthalmology Source Type: research

Comparison of new monofocal innovative and standard monofocal intraocular lens after phacoemulsification
ConclusionTecnis® Eyhance appears to be an effective option for both patients and surgeons regarding better intermediate visual acuities and more forgiving for residual refractive errors relative to the standard monofocal intraocular lenses. However, longer follow-up studies with larger group of patients are needed to evaluate the effectiveness of Tecnis® Eyhance intraocular lens. (Source: International Ophthalmology)
Source: International Ophthalmology - September 5, 2020 Category: Opthalmology Source Type: research

Sensitivity and specificity of choroidal thickness measurement by EDI-OCT for central serous chorioretinopathy diagnosis
AbstractPurposeTo evaluate the utility of choroidal thickness (CT) measurement by enhanced depth imaging optical coherence tomography (EDI-OCT) for central serous chorioretinopathy (CSC) diagnosis.MethodsCross-sectional comparative study of 62 consecutive patients: 38 with acute CSC and 24 with macular subretinal fluid from differential diagnoses (DD). Subfoveolar choroidal thickness was measured using EDI 9-mm horizontal protocol. We evaluated sensitivity, specificity and intraclass correlation coefficient.ResultsMean subfoveolar CT was greater in CSC group than in DD group (465.45  ± 115.42 μ...
Source: International Ophthalmology - September 3, 2020 Category: Opthalmology Source Type: research

Ocular tropism of coronavirus (CoVs): a comparison of the interaction between the animal-to-human transmitted coronaviruses (SARS-CoV-1, SARS-CoV-2, MERS-CoV, CoV-229E, NL63, OC43, HKU1) and the eye
ConclusionsData aggregation for coronaviruses shows a relatively low eye-tissue tropism. Conjunctival congestion is an uncommon manifestation of COVID-19 similar to all human coronaviruses ’ infections. In a low percentage of patients, the virus can be excreted in ocular fluids at different stages of the infection, regardless of positive SARS-Cov-2 throat swab. Albeit high viral loads in ocular tissue seem to have relatively low prevalence, the eye should be regarded as a potential source of infection dissemination for COVID-19. (Source: International Ophthalmology)
Source: International Ophthalmology - September 2, 2020 Category: Opthalmology Source Type: research

The effect of spleen tyrosine kinase inhibitor R406 on diabetic retinopathy in experimental diabetic rats
ConclusionSyk inhibitor R406 could attenuate retinal inflammation in DR rats via the repression of NF- κB activation. (Source: International Ophthalmology)
Source: International Ophthalmology - August 31, 2020 Category: Opthalmology Source Type: research

Characteristics of genotype and phenotype in Chinese patients with Bardet –Biedl syndrome
ConclusionsThis study showed the phenotypic and genotypic spectrum of BBS patients from China, and the findings underscore the importance of obtaining comprehensive clinical observations and molecular analyses for ciliopathies. (Source: International Ophthalmology)
Source: International Ophthalmology - August 31, 2020 Category: Opthalmology Source Type: research

Diurnal fluctuations of macular vessel density in patients with primary open-angle glaucoma and healthy subjects
ConclusionsWhether it is a max –min or a CV assessment method, the POAG eyes had more significant diurnal fluctuations of macular VD than healthy controls, suggesting impaired vascular autoregulation in POAG eyes. (Source: International Ophthalmology)
Source: International Ophthalmology - August 31, 2020 Category: Opthalmology Source Type: research

Syphilitic retinitis presentations: punctate inner retinitis and posterior placoid chorioretinitis
AbstractPurposeTo describe two distinct presentations of syphilitic fundus features in a series of patients with ocular syphilis.MethodsThis is a retrospective, interventional case series of 22 eyes from 16 serology confirmed cases. Clinical examination, fluorescein angiography, and optical coherence tomography were performed at presentation and following high-dose intravenous penicillin G.ResultsIn our cohort, the mean age was 47.6  years (range 24–59 years) and 14 patients were male (87.5%), 11 patients were positive for human immunodeficiency virus (68.8%), and 6 had bilateral involvement (37.5%). Mean b...
Source: International Ophthalmology - August 31, 2020 Category: Opthalmology Source Type: research

The efficacy of gonioscopy-assisted transluminal trabeculectomy combined with phacoemulsification
AbstractPurposeTo investigate the efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) with or without cataract extraction (CE) in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEX) patients.MethodsA retrospective, non-randomized study included 108 eyes of 108 patients, with a mean age of 65.96  ± 14.84 years, who underwent GATT to treat open-angle glaucoma. We have compared two groups, GATT alone or GATT combined with CE and followed-up minimum for 12 months. Preoperative intraocular pressure (IOP), best-corrected visual acuity (BCVA) compared wit...
Source: International Ophthalmology - August 30, 2020 Category: Opthalmology Source Type: research

Molecular and clinical characterization of Thai patients with achromatopsia: identification of three novel disease-associated variants in the CNGA3 and CNGB3 genes
ConclusionsThis study demonstrated the first molecular and clinical characterization of ACHM in Thai patients. The identification of disease-associated genes in a specific population leads to a personalized gene therapy benefiting those affected patients. (Source: International Ophthalmology)
Source: International Ophthalmology - August 30, 2020 Category: Opthalmology Source Type: research

Two-staged surgery as an alternative to buckle –vitrectomy for rhegmatogenous retinal detachment complicated by choroidal detachment
ConclusionSurgical outcomes were similar in both the groups. No clinically apparent toxicity was seen with post-operative short-term PFCL tamponade. Two-staged surgery is a good alternative to buckle –vitrectomy for eyes with RRD associated with CD. (Source: International Ophthalmology)
Source: International Ophthalmology - August 27, 2020 Category: Opthalmology Source Type: research

Ophthalmic artery resistance index after peribulbar block in the presence of epinephrine
ConclusionsA decrease in RI was observed in the OA after peribulbar block with a vasoconstrictor, an effect that could be a benefit in some ocular surgeries. (Source: International Ophthalmology)
Source: International Ophthalmology - August 27, 2020 Category: Opthalmology Source Type: research

Agreement of white-to-white measurements with swept-source OCT, Scheimpflug and color LED devices
AbstractPurposeTo assess the interchangeability of different devices for measuring white-to-white (WTW) distance.MethodsWTW distance was measured in 53 eyes of 53 patients using Anterion swept-source optical coherence topographer (SS-OCT), IOLMaster 700 SS-OCT, Pentacam HR Scheimpflug and Cassini color LED. Statistical analysis was done by means of the Friedman test and the post hoc Tukey test. The Bland –Altman analysis was applied to carry out pairwise comparisons with the average difference, 95% confidence interval of the average difference and limits of agreement 95% (LoA).ResultsWTW values obtained by the Anteri...
Source: International Ophthalmology - August 27, 2020 Category: Opthalmology Source Type: research

The impact of hybrid contact lenses on keratoconus progression after accelerated transepithelial corneal cross-linking
ConclusionThe CDVA significantly improved, and KCN progression was halted in patients wearing HCL 12  months after A-TE CXL. Besides, FCAsym indices can be considered for follow-up of the HCL-wearing patients as an assistive parameter to AS-OCT measurements. (Source: International Ophthalmology)
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

Is optical coherence tomography angiography a useful tool in the screening of hydroxychloroquine retinopathy?
AbstractPurposeTo detect the early changes in retinal vasculature via optical coherence tomography angiography (OCTA) by comparing the quantitative OCTA parameters in the group of patients who were using hydroxychloroquine (HCQ) or not.MethodsThis was a cross-sectional, comparative, and observational study. The patients who were newly or previously prescribed HCQ for an autoimmune disease were included. OCTA imaging was performed via OCT RT XR Avanti with AngioVue software (Optivue Inc, Freemont, CA). The study group had two groups: a control group (patients newly diagnosed and who were not taking any medication) and a tre...
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

Effect of phacoemulsification surgery on intraocular pressure and function of bleb after trabeculectomy
AbstractPurposeTo evaluate the effect of phacoemulsification (PE) surgery on intraocular pressure (IOP) control and morphology of filtering bleb in eyes that have previously had trabeculectomy in the long-term.MethodsThis retrospective study included 98 eyes of 93 patients who had undergone trabeculectomy first and then PE surgery. The IOP, morphology of bleb, the number of glaucoma medication of each patient before PE, and 1  day, 1 month, 3 months, 1 year, 2 years after PE, and at the last visit were recorded. The need for additional glaucoma medication or glaucoma surgery were noted. Surgical su...
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

Comparison of trabectome and microhook surgical outcomes
AbstractBackgroundSeveral methods can be applied for a trabeculotomy, including the uses of thread, a blade, cauterization, and a hook. We compared the outcomes of trabectome surgery and microhook surgery.MethodsWe analyzed the cases of 133 eyes that underwent trabectome (72 eyes) or microhook (61 eyes) surgery and were followed for>  1 year. We defined failure as a
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

Correction to: Visual, refractive and topographic outcomes of progressive thickness intrastromal corneal ring segments for keratoconic eyes
In the original publication, the Results paragraph of the abstract was published incorrectly. The correct version should read as follows. (Source: International Ophthalmology)
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

The association between exposure to radiation and the incidence of cataract
AbstractObjectiveTo examine the association between exposure to radiation from computed tomography (CT) studies and the incidence of cataract.MethodsIn a nested case –control study, all cataract cases and their matched controls were sampled from a retrospective cohort of Israeli residents who underwent CT scans or ultrasonic tests in Soroka Medical Center, Beer-Sheva, Israel, between the years 1996 and 2014. The risk of cataract associated with head, neck or t he rest of the body CT was assessed using Poisson survival analysis.ResultsThe nested matched sample included 3841 cataract cases and their age- and sex-matche...
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

Pentacam corneal densitometry-guided treatment of adenoviral corneal subepithelial infiltrates: a comparative study between transepithelial phototherapeutic keratectomy and topical tacrolimus
ConclusionTe-PTK and topical tacrolimus are effective methods for the treatment of adenoviral corneal SEIs improving visual acuity, corneal densitometry, and corneal HOA. The densitometry program of the Pentacam may give an objective guide for the treatment of adenoviral corneal SEIs.Trial registration: ClinicalTrials.gov ID is NCT04267991. (Source: International Ophthalmology)
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

The role of primary needle revision after Ahmed glaucoma valve (AGV) implantation
AbstractPurposeTo evaluate the efficacy and safety of primary needle revision after Ahmed Glaucoma Valve (AGV) implantation in comparison with glaucoma medication use.MethodsIn this interventional case series, 23 eyes of 23 patients who underwent AGV implantation were enrolled. Needle revision was performed when the intraocular pressure was higher than the target pressure before glaucoma medications. Using a 30-gauge needle, the Tenon ’s capsule over the plate was incised and the bleb was reformed. Patients were examined on a postoperative day one, weekly (for four weeks), and every 1–3 months. Two criteri...
Source: International Ophthalmology - August 26, 2020 Category: Opthalmology Source Type: research

Comparison of vessel density in macular and peripapillary regions between primary open-angle glaucoma and pseudoexfoliation glaucoma using OCTA
ConclusionPXG eyes were found to have lesser values in terms of VD in the macular area, especially in the parafoveal and FD-300 regions, compared to POAG eyes which had similar functional and structural glaucomatous damage. Patients whose etiology was PXG and who seemed to have the same functional damage as those with POAG were actually found to have greater macular vascular damage. In addition, it was observed that macular vascular parameters correlated with peripapillary vascular parameters. (Source: International Ophthalmology)
Source: International Ophthalmology - August 25, 2020 Category: Opthalmology Source Type: research