Diagnostic performance of laser speckle flowgraphy in glaucoma: a systematic review and meta-analysis
ConclusionsGlaucoma is closely related to ocular blood flow changes. This meta-analysis suggests that LSFG is a feasible diagnostic tool for glaucoma. However, further longitudinal prospective studies are needed. (Source: International Ophthalmology)
Source: International Ophthalmology - October 22, 2021 Category: Opthalmology Source Type: research

Impact of age, sex and refractive error on conjunctival and Tenon ’s capsule thickness dimensions by swept-source optical coherence tomography in a large population
AbstractPurposeTo evaluate conjunctival and Tenon ’s capsule thickness (CTT) in a large healthy population using swept-source optical coherence tomography (SS-OCT), investigating the impact of age, sex and refractive error.Methods630 healthy participants underwent a complete ophthalmological examination. CTT was manually measured in the temporal and nasal quadrants at 0, 1, 2 and 3  mm from the scleral spur using SS-OCT (CTT0, CTT1, CTT2 and CTT3, respectively). These dimensions were then assessed for associations in a multivariate regression model with age, sex, refractive error and anterior scleral thickness (...
Source: International Ophthalmology - October 22, 2021 Category: Opthalmology Source Type: research

Increased serum cortisol is associated with alterations in cross-sectional and topographic OCT parameters in diabetic retinopathy: a preliminary study
This study for the first time evaluated the association of serum cortisol with spectral domain optical coherence tomography (SD-OCT)-based cross-sectional and topographic parameters with severity of diabetic retinopathy (DR).MethodsA tertiary care center-based preliminary study was undertaken. Fourteen consecutive cases of DR and fifteen healthy controls were included. Cases were graded according to ETDRS classification: non-proliferative DR (NPDR,n = 8) and proliferative DR (PDR,n = 6). All study subjects underwent complete ophthalmological evaluation. Serum cortisol was analyzed using chemilum...
Source: International Ophthalmology - October 22, 2021 Category: Opthalmology Source Type: research

MicroRNA-93-5p participates in type 2 diabetic retinopathy through targeting Sirt1
ConclusionMiR-93-5p, via targeting Sirt1, could affect the vascular permeability and acellular capillaries and mitigate the inflammation and oxidative stress in the retinas, which may play a critical role in DR. (Source: International Ophthalmology)
Source: International Ophthalmology - October 22, 2021 Category: Opthalmology Source Type: research

Regional analysis of segmented-macular structure in patients with myopic anisometropia
ConclusionWhile the fovea is less affected by myopia, thinning becomes remarkable in the perifoveal quadrants. Despite thinning in many layers, especially INL and OPL, NFL thickening may be seen due to myopia. (Source: International Ophthalmology)
Source: International Ophthalmology - October 22, 2021 Category: Opthalmology Source Type: research

Ocular manifestations of HLA B 27 associated uveitis: a study of 255 cases from a tertiary eye care centre from South India
ConclusionHLA-B27-associated uveitis can be associated with higher number of posterior segment involvement than it is estimated and aggressive therapy in moderate-to-severe uveitis can prevent severe visual impairment in these patients. (Source: International Ophthalmology)
Source: International Ophthalmology - October 22, 2021 Category: Opthalmology Source Type: research

Evaluation of systemic immune-inflammation index level as a novel marker for severity of noninfectious uveitis
AbstractPurposeTo evaluate the association of systemic immune-inflammation index (SII) levels, neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) with severity ofnoninfectious uveitis.MethodsThis retrospective study included 46 patients with noninfectious uveitis (uveitis group) and 46 age- and sex-matched healthy subjects (control group). The demographic and ocular findings, localization, and activity of uveitis were recorded at the time of onset evaluation. SII, NLR, and PLR levels of patients were compared between the groups.ResultsSII, NLR, and PLR levels were significantly higher in uveitis group w...
Source: International Ophthalmology - October 22, 2021 Category: Opthalmology Source Type: research

Associated risk factors of postoperative pain after glaucoma surgery: a prospective study
ConclusionPatients undergoing glaucoma surgery tend to experience postoperative pain in the early postoperative period. Anxiety level and surgery types of cyclophotocoagulation and phacotrabeculectomy are risk factors for postoperative pain. Patients with diabetes and/or hypertension are less likely to develop postoperative pain. (Source: International Ophthalmology)
Source: International Ophthalmology - October 21, 2021 Category: Opthalmology Source Type: research

Juvenile idiopathic arthritis-associated  uveitis in the era of biological therapy: how the disease changed in more than 20 years of observation in a tertiary referral center in Rome (Italy)
AbstractObjectivesTo describe the ophthalmological characteristics in a Juvenile idiopathic arthritis (JIA) cohort and to evaluate how therapeutic advances have changed the course of the uveitis.MethodsAnalysis of a retrospective cohort study of consecutive JIA pediatric patients including JIA-associated uveitis (JIA-U) and comparison with a previous study in the same uveitis center assessed before the wide-spread of biological therapy.ResultsThe total of 49 JIA patients were analyzed, of whom 18 JIA-U, compared with a JIA-U past cohort of 66 patients. Systemic corticosteroids were used significantly less in the current JI...
Source: International Ophthalmology - October 20, 2021 Category: Opthalmology Source Type: research

Refractive changes with post-rotatory nystagmus in healthy individuals
ConclusionsThese findings suggest that the accommodation was functional during the post-rotatory nystagmus to compensate for the retinal image slip, and the accommodative convergence can help weaken the nystagmus. (Source: International Ophthalmology)
Source: International Ophthalmology - October 19, 2021 Category: Opthalmology Source Type: research

Fixation stability improvement after occlusion treatment for severe amblyopia
AbstractBackgroundTo investigate the improvement of fixation stability of severe amblyopia with traditional patching treatment by the MP-1 microperimeter.MethodsEighteen patients with severe unilateral amblyopia were enrolled and received prescribed 6  h per day of patching of the fellow eye with optical correction if needed. Fixation test was performed on eighteen severe unilateral amblyopia patients by the MP-1 microperimeter in baseline, 3-month and 6-month after treatment. The bivariate contour ellipse area (BCEA, deg2) was used to quantify fixation stability.ResultsThe RMANOVA showed that significant differences ...
Source: International Ophthalmology - October 19, 2021 Category: Opthalmology Source Type: research

A retrospective review of XEN implant surgery: efficacy, safety and the effect of combined cataract surgery
AbstractObjectivesTo investigate the safety and efficacy of glaucoma XEN stent implantation and examine the effect of undergoing combined phacoemulsification and XEN versus XEN implant alone.MethodsA retrospective case note review of patients who underwent XEN implantation by a single surgeon over a 24-month period was performed. Outcomes included changes in IOP and medication use after XEN implant insertion as well as complications post-surgery. Subgroup analysis was also performed, separating phaco-XEN (phacoemulsification and XEN implantation) and stand-alone XEN implantation.Results186 XEN implant procedures were inclu...
Source: International Ophthalmology - October 19, 2021 Category: Opthalmology Source Type: research

Comparison of obstructive sleep apnea syndrome and keratoconus patients on elevation maps
ConclusionThe study reveals the tomographic corneal characteristics and topometric and pachymetric indices of patients with severe OSAS at the time of diagnosis; these findings statistically significantly differ from the control group. In addition to the known association of floppy eyelid in OSAS patients, the suspicion of keratoconus should be kept in mind. (Source: International Ophthalmology)
Source: International Ophthalmology - October 18, 2021 Category: Opthalmology Source Type: research

Evaluation of a uniplanar pupil expansion ring in small-pupil cataract surgery: a feasibility study
AbstractPurposeThe aim of this study was to evaluate the effectiveness of a disposable uniplanar pupil expansion device in small-pupil cataract surgery.MethodsThis is a feasibility study carried out at the Rothschild Foundation, Paris, France. Patients undergoing routine cataract surgery with a dilated pupil size  
Source: International Ophthalmology - October 16, 2021 Category: Opthalmology Source Type: research

Assessment of eye drop instillation techniques among patients with primary open angle glaucoma in a Nigerian tertiary hospital
This study was a cross-sectional observational study conducted among 130 participants. Systematic sampling technique was used. Inclusion criteria were the presence of POAG, in individuals  ≥ 18 years, and self-instilling their ocular hypotensive medications for at least 6 months. Demographic data and clinical characteristics were obtained using an interviewer-administered questionnaire and clinical examination. All participants underwent eye drop instillation of sterile water . Administration techniques were observed and graded using a comprehensive grading scheme. Patients with poor techniques w...
Source: International Ophthalmology - October 16, 2021 Category: Opthalmology Source Type: research

12-Month Outcomes of Combined Phacoemulsification and iStent Inject in Asian Eyes with Normal Tension Glaucoma: A Single-Centre Experience
AbstractPurposeTo evaluate efficacy and safety of the iStent inject combined with phacoemulsification in Asian eyes with normal-tension glaucoma (NTG) up to 12  months after surgery.Study designRetrospective case series.MethodsRetrospective case series of eyes undergoing surgery from April 2017 to August 2019. Outcome measures included intraocular pressure (IOP), number of topical glaucoma medications and adverse outcomes. Data were retrieved from the post-operative day 1 (POD1), week 1 (POW1), month 1 (POM1), month 3 (POM3), month 6 (POM6) and month 12 (POM12) timepoints. Data were analysed at each timepoint for eyes...
Source: International Ophthalmology - October 15, 2021 Category: Opthalmology Source Type: research

Outcomes of flanged IOL fixation combined with microhook trabeculotomy
ConclusionsThis study showed that flanged intraocular lens fixation combined with microhook trabeculotomy might be effective for exfoliation glaucoma with subluxated lens or intraocular lens. (Source: International Ophthalmology)
Source: International Ophthalmology - October 15, 2021 Category: Opthalmology Source Type: research

Evaluation of primary Ahmed Glaucoma valve implantation in post-traumatic angle recession glaucoma in Indian eyes
This study included 52 patients of angle recession glaucoma, who presented between Mar 2006 to Feb 2016, out of which 38 patients had undergone primary AGV implantation, while the rest were managed with topical anti-glaucoma medications. Preoperative data included age, sex, type and mode of injury, duration of injury, assessment of best-corrected visual acuity (BCVA) and intraocular pressure (IOP). The extent of angle recession was observed by gonioscopy. The intraocular pressure, visual acuity, and the number of anti-glaucoma medications were measured postoperatively. The success of this technique was analyzed by using a ...
Source: International Ophthalmology - October 14, 2021 Category: Opthalmology Source Type: research

Nomogram for single-pass automated microkeratome graft preparation for ultrathin Descemet stripping automated endothelial keratoplasty
AbstractPurposeTo create a nomogram including the translational speed of the microkeratome blade, microkeratome head size and precut tissue thickness to predict the postcut thickness for Descemet stripping automated endothelial keratoplasty to obtain the thinnest possible graft.MethodsThis prospective study incorporated 48 grafts for DSAEK from March 2017 to June 2020. Corneal tissue for DSAEK was prepared by 3 experienced physicians using the Moria Evolution 3E (Moria Inc, Antony, France) microkeratome with 400, 450 and 500  μm head sizes. Precut central corneal thickness was measured with a DGH 550 handheld pachy...
Source: International Ophthalmology - October 13, 2021 Category: Opthalmology Source Type: research

Pars plana subcapsulotomy to remove condense subcapsular opacification in combined surgery of silicone oil removal and phacoemulsification
AbstractPurposeBecause of the direct contact of intravitreal silicone oil (SO) with the subcapsular membrane, cataract is one of the main SO-related complications. In a group of patients, condense subcapsular opacification occurs, which adds difficulty and risk when having sequential treatment of it. The aim of the current study is to assess the long-term outcomes of pars plana subcapsulotomy to remove condense subcapsular opacification in combined surgery of SO removal and phacoemulsification.MethodsRetrospective cohort study. Consecutive patients who were scheduled to have combined surgery of SO removal and phacoemulsifi...
Source: International Ophthalmology - October 13, 2021 Category: Opthalmology Source Type: research

Graft survival and clinical outcomes of Descemet membrane endothelial keratoplasty: long-term results
ConclusionAlthough DMEK is effective and safe in long term, visual results and graft survival rates are better in cases with FECD. (Source: International Ophthalmology)
Source: International Ophthalmology - October 12, 2021 Category: Opthalmology Source Type: research

Altered peripapillary vessel density and nerve fiber layer thickness in thyroid-associated ophthalmopathy using optical coherence tomography angiography
AbstractObjectiveTo measure the peripapillary vessel density (VD) and retinal nerve fiber layer thickness (RNFLT) in thyroid-associated ophthalmopathy (TAO) and dysthyroid optic neuropathy (DON) patients using optical coherence tomography angiography (OCTA), and determine their prognostic relevance.MethodsForty-three TAO patients with or without DON (82  eyes in total) and 26 healthy subjects (52 eyes) were enrolled. All participants underwent ophthalmology and endocrinology tests. The peripapillary VD in retinal peripapillary capillary layer and RNFLT were analyzed using OCTA images. Multiple linear regression analys...
Source: International Ophthalmology - October 12, 2021 Category: Opthalmology Source Type: research

Understanding the role of corneal biomechanics-associated genetic variants by bioinformatic analyses
AbstractPurposeTo analyze functions of corneal biomechanical properties (CBP)-related variants as corneal resistance factor (CRF) and corneal hysteresis (CH).MethodsRelated single nucleotide polymorphisms (SNPs) and genes were identified from NHGRI-EBI GWAS catalog, GWASdb v2 and possible data in published studies. HaploReg v4.1 was used to find linkage SNPs. Functional annotations were performed by GWAVA, CADD and RegulomeDB. GTEx Portal database was used to find out expression quantitative trait locus (eQTL) association. Enrichr was used to annotate the function of GWAS gene and the associated signal pathway. STING (v11....
Source: International Ophthalmology - October 12, 2021 Category: Opthalmology Source Type: research

Wide-field vitreoretinal surgery in eyes with Boston type 1 keratoprosthesis
ConclusionIn eyes with a Boston KPro, wide-angle viewing systems helped handling peripheral retinal problems successfully during PPV, with no observed inadequacy of imaging. Despite anatomical success in most cases, visual prognosis depends on vitality of the macula and the optic disc. (Source: International Ophthalmology)
Source: International Ophthalmology - October 12, 2021 Category: Opthalmology Source Type: research

Comparison of the effect of removing bandage contact lens on the days 3 and 5 following photorefractive keratectomy
AbstractAimTo compare the outcomes of removing bandage contact lens (BCL) on days 3 and 5 after photorefractive keratectomy (PRK).MethodsOne hundred patients who underwent PRK (a total of 200 eyes) were enrolled in the present study. The subjects were assigned to two groups. Group 1 consisted of the right eyes of subjects and bandage contact lenses removal were on the 3rd day; Group 2 consisted of the fellow eyes of same subjects and removed bandage contact lenses on the 5th day after PRK. Then, data obtained from both groups were compared. To evaluate complications, the subjects underwent a slit-lamp examination in all vi...
Source: International Ophthalmology - October 12, 2021 Category: Opthalmology Source Type: research

The use of fixed dose drug combinations for glaucoma in clinical settings: a retrospective, observational, single-centre study
ConclusionMore than 60% of the combinations were used together with other anti-glaucoma drugs. The advantages of these fixed dose combinations in improving patient compliance need to be reassessed in real-word settings. Prescriptions containing duplicated ingredients were common. However, they were not necessarily considered unreasonable because the dosage forms were administered at different times. For prescriptions containing repetitive ingredients, pharmacists should judge the rationale by evaluating the dosing frequency and drug indications and explain the appropriate administration to patients. (Source: International Ophthalmology)
Source: International Ophthalmology - October 12, 2021 Category: Opthalmology Source Type: research

Correlation of optical coherence tomography and Doppler ultrasonography findings in pseudoexfoliation syndrome
AbstractPurposeWe aimed to investigate the correlation between the color Doppler imaging (CDI) results and parameters determined by spectral domain optical coherence tomography (SD-OCT) in cases with pseudoexfoliation syndrome (XFS).Methods99 participants were included in this prospective study. Retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), optic nerve head (ONH) measurements were recorded. Perfusions of the ophthalmic artery (OA) and central retinal artery (CRA) were determined and resistivity indices (RI) were calculated.ResultsNo statistically significant differences were determined between the groups r...
Source: International Ophthalmology - October 11, 2021 Category: Opthalmology Source Type: research

Use of corneal hysteresis and corneal resistance factor in target intraocular pressure estimation in patients with early primary open-angle glaucoma
AbstractPurposeTo introduce a new method for estimation of the target intraocular pressure (TIOP) in na ïve eyes with early primary open-angle glaucoma (POAG) using corneal hysteresis (CH) and corneal resistance factor (CRF).MethodsA prospective quasi-experimental study was conducted on na ïve 90 eyes of 45 patients who were newly diagnosed with early primary open-angle glaucoma (POAG). They were compared to 72 eyes of 36 normal subjects. The TIOP was determined for each eye. The IOP Goldmann (IOPg), IOP corneal-compensated (IOPcc), CH and CRF were estimated by ocular response analyz er (ORA, Reichert) device. Me...
Source: International Ophthalmology - October 11, 2021 Category: Opthalmology Source Type: research

Optical coherence tomography angiography characteristics and correlated factors with visual acuity in retinal arterial occlusion
AbstractPurposeTo reveal the characteristics of vascular changes in retinal arterial occlusion (RAO) using optical coherence tomography angiography (OCTA) and determine the correlated factors with best-corrected visual acuity (BCVA).MethodsThis retrospective study recruited 54 RAO patients and 27 healthy individuals. Ophthalmic examinations including BCVA and OCTA were performed in all the patients and individuals. The OCTA outcomes were analyzed using SPSS software, and the characteristics of vascular changes and BCVA-related factors were summarized.ResultsThe vessel density in all areas except fovea of both superficial c...
Source: International Ophthalmology - October 11, 2021 Category: Opthalmology Source Type: research

Outcomes of the infantile cataract surgery: case series with a 5-year follow-up
ConclusionDue to high prevalence rates of amblyopia, strabismus, and glaucoma after the infantile cataract surgery, specific attention should be paid to these complications in each follow-up examination. (Source: International Ophthalmology)
Source: International Ophthalmology - October 11, 2021 Category: Opthalmology Source Type: research

Circ_0075804 promotes the malignant behaviors of retinoblastoma cells by binding to miR-138-5p to induce PEG10 expression
ConclusionCirc_0075804 promoted RB progression via miR-138-5p-dependent regulation of PEG10, which provided new insight in RB therapy. (Source: International Ophthalmology)
Source: International Ophthalmology - October 11, 2021 Category: Opthalmology Source Type: research

Comparative analysis of two optical biometry devices: high wavelength swept source OCT versus partial coherence interferometry
AbstractPurposeTo study the reproducibility of measurements performed with a recently developed multimodal high resolution swept source optical coherence tomography (SSOCT) and to make comparisons with a partial coherence interferometry (PCI) biometer.MethodsOne hundred and fifty-two eyes of 152 subjects were involved in this study with a mean age of 65.71  ± 13.86 years (26–85 years). Anterior surface keratometry (K), anterior chamber depth (ACD), white-to-white (WTW) and axial length (AL) values were recorded by the SSOCT (ANTERION, Heidelberg Engineering Ltd, Germany) and PCI (IOLMas...
Source: International Ophthalmology - October 11, 2021 Category: Opthalmology Source Type: research

Ahmed glaucoma valve implantation with the tube placement in the ciliary sulcus: short-term results
AbstractPurposeTo evaluate the clinical outcomes of pseudophakic/aphakic eyes with uncontrolled glaucoma that underwent Ahmed glaucoma valve implantation with the tube placement in the ciliary sulcus.MethodsMedical records of the patients who underwent Ahmed glaucoma valve implantation through the ciliary sulcus, between December 2017 and June 2019, were reviewed retrospectively. Patients ’ age, gender, glaucoma diagnosis, visual acuity, intraocular pressure levels, and complications were recorded.ResultsForty-seven eyes of 43 patients with glaucoma were enrolled. The mean age was 54.5  ± 19.9&nb...
Source: International Ophthalmology - October 10, 2021 Category: Opthalmology Source Type: research

Five-year outcomes after intravitreal bevacizumab of treatment-naive eyes with macular edema secondary to CRVO in routine clinical practice: Results of the Pan-American Collaborative Retina Study (PACORES) group
AbstractPurposeThe purpose of this study was to report the 5-year outcomes of treatment-naive eyes with cystoid macular edema secondary to central retinal vein occlusion treated with intravitreal bevacizumab in routine clinical practice.MethodsWe conducted multicenter retrospective non-comparative case series of 102 eyes. The main outcome measured was the change in best-corrected visual acuity (BCVA) at 5  years. Secondary outcomes included the number of injections and the change in CMT at 5 years.ResultsAt 5  years, the mean BCVA improved from 1.22 ± 0.58 (Snellen 20/428) at baseline to...
Source: International Ophthalmology - October 9, 2021 Category: Opthalmology Source Type: research

Comparison of clinical usefulness of central 30 –2 and 24–2 threshold tests using SITA strategy
AbstractPurposeTo compare the clinical utilities of the SITA-based central 24 –2 and 30–2 threshold tests.MethodsThree hundred sixty-five (365) eyes of 183 glaucoma and glaucoma suspect patients who had undergone both central 30 –2 and 24–2 threshold testing using the Swedish interactive threshold algorithm (SITA) standard strategy were retrospectively reviewed. The tests were performed in patients with a minimum visual acuity of LogMAR best-corrected visual acuity (BCVA) 0.3. We compared test time, fixation loss (%), f alse-positive error rate (%), and false-negative error rate (%), all of which ar...
Source: International Ophthalmology - October 9, 2021 Category: Opthalmology Source Type: research

Clinical variations and therapeutic challenges in the management of symptomatic retinal artery macroaneurysm: a tertiary center experience
ConclusionWith regard to its presentation, which can vary tremendously, there are no approved guidelines for its treatment. The present study reinforces the need for a treatment guideline development. Customization of treatment should be considered depending on the clinical presentation of each case. (Source: International Ophthalmology)
Source: International Ophthalmology - October 9, 2021 Category: Opthalmology Source Type: research

Evaluation of early retinal vascular changes by optical coherence tomography angiography in children with type 1 diabetes mellitus without diabetic retinopathy
ConclusionIn children with T1DM without clinically apparent DR, VD in SCP and DCP was decreased and OCTA is a valuable imaging technique for detecting early vascular changes. The metabolic parameters such as mean HbA1c, IGF-1 SDS and Hcy affect the macular VD in diabetic children.Trial registration number: 2011-KAEK-2, 2021/4,Trial registration date: 02.04.2021. (Source: International Ophthalmology)
Source: International Ophthalmology - October 8, 2021 Category: Opthalmology Source Type: research

Fovea sparing versus complete internal limiting membrane peeling for myopic traction maculopathy: a meta-analysis
ConclusionFSIP resulted in similar anatomic outcomes compared to CIP, but resulted in better visual acuity and lower rates of postoperative MH development. (Source: International Ophthalmology)
Source: International Ophthalmology - October 8, 2021 Category: Opthalmology Source Type: research

Multifocal IOL explantation in patients with opaque lentis after refractive lens exchange
We describe the outcomes of intraocular lens (IOL) explantation in a cluster of opaque multifocal Lentis LS-313 following refractive lens exchange (RLE).MethodsSingle-centre, single-surgeon, retrospective case series.ResultsThe study enrolled 10 eyes of 10 patients, 6 male and 4 female. All patients had uneventful RLE with multifocal IOL implantation. The mean patient age at the time of RLE was 53  years ± 2.52 (SD). Two eyes had YAG laser capsulotomy prior to explantation. The mean interval between the initial RLE and IOL explantation was 5.4 years ± 1.4 (SD). IOL exchan...
Source: International Ophthalmology - October 8, 2021 Category: Opthalmology Source Type: research

Increasing metabolic variability increases the risk for vitrectomy in proliferative diabetic retinopathy
AbstractPurposeProliferative diabetic retinopathy (PDR) can be treated by retinal photocoagulation, but in some cases, the treatment is initiated too late or is insufficient so that the disease advances to a stage requiring vitrectomy. There is a need to identify risk factors that can predict if patients with PDR will develop complications in need for vitrectomy.MethodsSurvival analysis with death as competing risk was used to study systemic risk factors for PDR progression to a complication in need for vitrectomy in right eyes of all 1288 diabetic patients from the Aarhus area, Denmark, who had developed proliferative ret...
Source: International Ophthalmology - October 8, 2021 Category: Opthalmology Source Type: research

A meta-analysis of prognostic biomarkers in neonatal retinal hemorrhage
ConclusionThe identified prognostic gene biomarkers may help to understand disease pathogenesis and provide a better diagnosis, prognosis, and treatment of neonatal RH. (Source: International Ophthalmology)
Source: International Ophthalmology - October 8, 2021 Category: Opthalmology Source Type: research

Comparison of the clinical features between posterior scleritis with exudative retinal detachment and Vogt –Koyanagi–Harada disease
ConclusionThere are characteristic differences in multimodal imaging parameters and clinical course between VKH and PS with ERD. (Source: International Ophthalmology)
Source: International Ophthalmology - October 8, 2021 Category: Opthalmology Source Type: research

Interocular asymmetry in distribution of leaks in central serous chorioretinopathy
AbstractPurposeTo study interocular asymmetry in distribution of leaks in central serous chorioretinopathy (CSC).Material and methodsPatients with unilateral CSC were included in this retrospective multicenter study. All patients received multimodal imaging. The prevalence of leaks within 1 disk diameter (DD) peripapillary area and the mean shortest distance between a leak and the optic disk edge was analyzed for the right and left eyes separately based on FA images. Clinical and morphological characteristics were collected and compared between eyes with a peripapillary leak and eyes with a leak elsewhere.ResultsIn total, ...
Source: International Ophthalmology - October 7, 2021 Category: Opthalmology Source Type: research

Age norms for grating acuity and contrast sensitivity in children using eye tracking technology
ConclusionsDIVE is an automatic, objective and reliable tool to assess several visual function parameters in children, and it has good agreement with classical VA tests, especially for the first stage of life. (Source: International Ophthalmology)
Source: International Ophthalmology - October 7, 2021 Category: Opthalmology Source Type: research

A novel technique of full-thickness scleral debridement in fulminant necrotising infectious scleritis and its outcomes —a consecutive case series
ConclusionThis study highlights the fulminant and relentlessly progressive clinical course, that infectious scleritis can metamorphose into, despite specific antimicrobial therapy, if inadvertent corticosteroid therapy is administered. Full-thickness debridement without scleral patch graft, could achieve elimination of infectious foci, with favourable long-term anatomical and visual outcome. This technique could offer a potential last-resort approach in such cases where standard therapeutic modalities have not been successful. (Source: International Ophthalmology)
Source: International Ophthalmology - October 6, 2021 Category: Opthalmology Source Type: research

The effect of topical bimatoprost on corneal clarity in primary open-angle glaucoma: a longitudinal prospective assessment
ConclusionsTopical bimatoprost administration might result in a decrease in corneal densitometry measurement. It is of clinical importance that topical bimatoprost administration can affect corneal transparency and cause a possible alteration in corneal properties. (Source: International Ophthalmology)
Source: International Ophthalmology - October 6, 2021 Category: Opthalmology Source Type: research

Pupil responses in patients with COVID-19
This study included 58 COVID-19 cases (mean age 47.23  ± 1.1 years). The scotopic, mesopic and photopic diameters were noted. Pupil diameters were noted at the 0, 1st, 2nd, 4th, 6th, 8th, and 10th seconds in reflex pupil dilation after the termination of a light. The average dilation speed was calculated at the 1st, 2nd, 4th, 6th, 8th, and 10th s econds. Pupil responses measured during COVID-19 infection and 3 months later were compared.ResultsThe mean scotopic and mesopic pupil diameter value of during COVID-19 infection was found lower than the 3rd month post-infection. (p = 0...
Source: International Ophthalmology - October 6, 2021 Category: Opthalmology Source Type: research

Diagnostic accuracy of Immulite ® TSI immunoassay for thyroid-associated orbitopathy in patients with recently diagnosed Graves’ hyperthyroidism
ConclusionsAlthough Immulite ® TSI level was higher in the presence of TAO, it showed poor diagnostic accuracy and no correlation with clinical markers of TAO severity or activity. (Source: International Ophthalmology)
Source: International Ophthalmology - October 6, 2021 Category: Opthalmology Source Type: research

Antibacterial effects of octadecyl trimethylammonium micelle –clay complex against bacterial eye pathogens: potential as a contact lens disinfectant
ConclusionRapid and potent antibacterial effects of ODTMA micelle –clay complex were observed in vitro; however, research is needed to determine precise formulation of contact lens disinfectants comprising ODTMA micelle–clay complex. Additionally, studies should be conducted using in vivo models of keratitis, progressing to pre-clinical and clinical trials. OD TMA micelle–clay complex is an ideal candidate to be incorporated in a novel contact lens disinfectant given the cost-effectiveness and ease of application and can be incorporated as an effective preventative strategy. (Source: International Ophthalmology)
Source: International Ophthalmology - October 6, 2021 Category: Opthalmology Source Type: research

Silodosin as a predisposing factor of intraoperative floppy iris syndrome (IFIS): an observational propensity score-matching cohort study
ConclusionSilodosin has been demonstrated as a predisposing factor, strongly correlated with IFIS development. These results should increase cataract surgeons ’ awareness to assess their patients preoperatively for exposure to silodosin carefully and employ the appropriate prophylactic measures to ameliorate the impact of silodosin intake on the surgical outcome. (Source: International Ophthalmology)
Source: International Ophthalmology - October 5, 2021 Category: Opthalmology Source Type: research