Visual performance and patient preference with bilateral implantation of an extended depth of focus or combined implantation of an extended depth of focus/trifocal intraocular lens
ConclusionsA combined implantation approach (AT LARA in the distance dominant eye/AT LISA tri in the non-dominant eye) produced similar CDVA outcomes but better UCNVA as bilateral implantation with the AT LARA. UIVA was comparable between groups. No new safety concerns were reported. (Source: International Ophthalmology)
Source: International Ophthalmology - February 14, 2024 Category: Opthalmology Source Type: research
Review of lipocalin-2-mediated effects in diabetic retinopathy
ConclusionsIn conclusion, LCN2, involved in the development of diabetic retinopathy, is a key factor in diabetic retinal microangiopathy, neurodegeneration, and retinal inflammation. LCN2 is likely to be a novel molecular target leading to DR, and a more in-depth study of the pathogenesis of DR caused by LCN2 may provide considerable benefits for clinical research and potential drug development. (Source: International Ophthalmology)
Source: International Ophthalmology - February 14, 2024 Category: Opthalmology Source Type: research
Impact of removing soft contact lenses 1 day versus 1 month before surgery on the outcomes of microkeratome laser in situ keratomileusis
ConclusionWith the absence of corneal warpage, no statistical or clinical difference in microkeratome LASIK outcomes and safety was spotted between the groups despite the difference in SCL discontinuation time before the procedure. (Source: International Ophthalmology)
Source: International Ophthalmology - February 14, 2024 Category: Opthalmology Source Type: research
Visual-functional impact of people affected by severe ocular trauma during social protests in Chile in 2019
ConclusionThe use of kinetic weapons for crowd control resulted in high and extreme VFIP and, in most cases, monocular blindness, causing major difficulties in work, study, and development of hobbies and pastimes in the affected population, highlighting the urgent need for effective rehabilitative care, which requires special attention in order to generate an adequate rehabilitation program. The use of kinetic weapons for crowd control contravenes international goals, policies, and plans set by the WHO and the International Agency for the Prevention of Blindness on strategies to prevent avoidable blindness worldwide until ...
Source: International Ophthalmology - February 14, 2024 Category: Opthalmology Source Type: research
Investigation of optic nerve function in Beh çet’s patients with optic disc hyperfluorescence in fundus fluorescein angiography
ConclusionAs far as we know, this is the first publication that investigates optic nerve function in BD patients with isolated OD hyperfluorescence in FA. Assessment with FA of asymptomatic BD patients with visual complaints and low contrast sensitivity may be helpful at early detection of inflammatory optic neuropathy by close follow-up in patients with OD hyperfluorescence. (Source: International Ophthalmology)
Source: International Ophthalmology - February 13, 2024 Category: Opthalmology Source Type: research
Higher incidence of meibomian gland dysfunction in postmenopausal women with primary acquired nasolacrimal duct obstruction
ConclusionsOur study revealed a prodominantly high incidence of MGD in postmenopausal women with PANDO, especially in a complete PANDO or aged < 70 years. Ophthalmologists need to pay close attention to MGD in postmenopausal women with PANDO. (Source: International Ophthalmology)
Source: International Ophthalmology - February 13, 2024 Category: Opthalmology Source Type: research
Zone 1 trauma: wound dehiscence compared to primary trauma
ConclusionZone 1 open globe injuries due to wound dehiscence may exhibit worse prognosis compared to primary trauma open globe injury. More important than the zone of injury may be the source. (Source: International Ophthalmology)
Source: International Ophthalmology - February 13, 2024 Category: Opthalmology Source Type: research
Unexpected findings: loss of corneal endothelial cells in Uygur patients with exfoliation syndrome
ConclusionsECD is reduced in XFS/XFG patients compared with age-related cataract subjects. It is crucial to remain vigilant to enhance surgical safety in XFS/XFG patients and prevent complications proactively. (Source: International Ophthalmology)
Source: International Ophthalmology - February 13, 2024 Category: Opthalmology Source Type: research
Long-term ocular surface stability in conjunctivolimbal autograft and ocular surface safety in the donor eyes
ConclusionsCLAU tissues provide ocular surface stability with a successful vision result in the long term. CLAU theoretically carries risks including limbal stem cell deficiency in the donor eye. In the long-term follow-up of donor eyes after CLAU, ectasia and limbal stem cell deficiency were observed in one eye. (Source: International Ophthalmology)
Source: International Ophthalmology - February 13, 2024 Category: Opthalmology Source Type: research
An alternative method to establish an early acute ocular toxoplasmosis model for experimental tests
ConclusionInfection of C57BL6 mice via intraperitoneal with 104 tachyzoites of the ME49-GFP strain from cell culture is a suitable model for acute ocular toxoplasmosis. This model has great reproducibility in establishing the ocular lesion since day 5 post-infection. This model can be suitable for experimental tests of chemotherapy and the investigation of the role of the immune response on the development of uveitis. (Source: International Ophthalmology)
Source: International Ophthalmology - February 13, 2024 Category: Opthalmology Source Type: research
Ochratoxin A induces mitochondrial dysfunction, oxidative stress, and apoptosis of retinal ganglion cells (RGCs), leading to retinal damage in mice
ConclusionOchratoxin A induces mitochondrial dysfunction, oxidative stress, and RGCs death in mice. (Source: International Ophthalmology)
Source: International Ophthalmology - February 13, 2024 Category: Opthalmology Source Type: research
Effects of injectable platelet-rich fibrin (i-PRF) on pterygium surgery with conjunctival autograft
ConclusionsThanks to its platelets-derived growth factors, i-PRF can be a safe and effective adjuvant therapy for faster healing of conjunctival autograft and in the prevention of recurrence. (Source: International Ophthalmology)
Source: International Ophthalmology - February 12, 2024 Category: Opthalmology Source Type: research
Effect of refractive errors on the results of botulinum neurotoxin administration in patients with infantile esotropia
ConclusionsBNT injection is a preferred method in IE. Higher hypermetropic values seem to increase the success of BNT injection. (Source: International Ophthalmology)
Source: International Ophthalmology - February 12, 2024 Category: Opthalmology Source Type: research
Pediatric keratoconus epidemiology: a systematic scoping review
ConclusionsRecent epidemiological studies with better methodologies demonstrated increased prevalence rates in comparison to the older literature. This effect may be due to better diagnostic methods and better sample selection than those in historical studies. Diagnosis remains a major challenge as the early disease is usually asymptomatic. Economic and social aspects of pediatric KC remain understudied in the pediatric literature. Global, inclusive, and proactive screening studies in schools are imperative to better understand the great impact of this disease in the young. (Source: International Ophthalmology)
Source: International Ophthalmology - February 12, 2024 Category: Opthalmology Source Type: research
High-throughput screening of transient receptor potential (TRP) channels in pterygium
ConclusionCollectively, TRP channel proteins appear to play pivotal roles in both the development and progression of pterygium, making them promising candidates for future therapeutic interventions in patients afflicted by this condition. (Source: International Ophthalmology)
Source: International Ophthalmology - February 12, 2024 Category: Opthalmology Source Type: research
